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The Portrait

by Glenn Rand Tim Meyer

Glenn Rand, longtime photographic educator and Program Director for Graduate Programs at Brooks Institute, and Tim Meyer, Portrait Division Chair at Brooks Institute, have collaborated to create a thorough and balanced textbook on the modern techniques and practice of portrait photography. They have avoided the single-style viewpoint common to so many books on portraiture and have crafted a definitive resource for professionals, as well as students and avid amateurs, wishing to advance their skills in this discipline. Topics include: Quality of light and the portrait Ambient, continuous, and strobe light sources Understanding light modifiers and enhancers Mastering lighting ratios Importance and selection of backgrounds Extensive coverage of lighting setups Understanding light meters and metering in portraiture Lighting patterns on the human face Facial analysis Composition in portraiture Eliciting the appropriate expression The fine art portrait Portraiture for the masses

Shaping Light

by Glenn Rand Tim Meyer

Whether shooting portraits or products, skillful lighting can be the difference between a bland snapshot and a stunning, well-defined image. Capturing the ideal photograph requires many technical factors to work in tandem, the most fundamental of which is lighting. While we may take it for granted that light is required to create a photograph, light by itself usually does not produce the style, energy, emotion or feeling that makes a photograph exceptional. It is the way the light has been modified and shaped that gives the photographer the ability to create an image that communicates their feeling about the subject. It's necessary to understand how light works in order to know how to modify it in the most desirous way.Beginning with simplified light concepts, Rand delves into the basics of light. Light's natural tendency is to go off in all directions. To give a better understanding of how to control the light that you use in your photographs, Rand guides the reader through a series of discussions defining the light itself, the surfaces that will interact with the light in the photographs, the look of light that we wish to create and the tools, modifiers and shapers that are commonly available for use. Whether you want to add contrast with highlights and shadows or use the softness of diffuse light to add volume to the subject, the fundamentals of these concepts are covered here. Images, diagrams and descriptions are used to illustrate the manners in which light can be modified.From there, the book moves onto the main tools of light modification. Rand discusses the primary functions of each tool and defines the issues of the light's characteristics after the modification. Techniques are presented for using reflectors, spotlights, softboxes, diffusers, umbrellas, barndoors, gels, scrims, shoots and more. Each chapter is highly illustrated with images of the tools being discussed, diagrams, and examples for the use of these tools in both commercial and portrait photography. Variations in control and problems that may occur with specific modifiers are discussed as well.The goal of this book is to show the effect of modifiers and shapers on the quality of light rather than to discuss the merits of a particular light source. By focusing on the methods to shape light, the photographer is open to improvise in scenarios where they may not have control over the light source. Whether you shoot commercial or portrait photography, this book provides you with the basis for not only successfully, but elegantly shaping light to create your desired result.

Shaping Light

by Glenn Rand Tim Meyer

Whether shooting portraits or products, skillful lighting can be the difference between a bland snapshot and a stunning, well-defined image. Capturing the ideal photograph requires many technical factors to work in tandem, the most fundamental of which is lighting. While we may take it for granted that light is required to create a photograph, light by itself usually does not produce the style, energy, emotion or feeling that makes a photograph exceptional. It is the way the light has been modified and shaped that gives the photographer the ability to create an image that communicates their feeling about the subject. It's necessary to understand how light works in order to know how to modify it in the most desirous way.Beginning with simplified light concepts, Rand delves into the basics of light. Light's natural tendency is to go off in all directions. To give a better understanding of how to control the light that you use in your photographs, Rand guides the reader through a series of discussions defining the light itself, the surfaces that will interact with the light in the photographs, the look of light that we wish to create and the tools, modifiers and shapers that are commonly available for use. Whether you want to add contrast with highlights and shadows or use the softness of diffuse light to add volume to the subject, the fundamentals of these concepts are covered here. Images, diagrams and descriptions are used to illustrate the manners in which light can be modified.From there, the book moves onto the main tools of light modification. Rand discusses the primary functions of each tool and defines the issues of the light's characteristics after the modification. Techniques are presented for using reflectors, spotlights, softboxes, diffusers, umbrellas, barndoors, gels, scrims, shoots and more. Each chapter is highly illustrated with images of the tools being discussed, diagrams, and examples for the use of these tools in both commercial and portrait photography. Variations in control and problems that may occur with specific modifiers are discussed as well.The goal of this book is to show the effect of modifiers and shapers on the quality of light rather than to discuss the merits of a particular light source. By focusing on the methods to shape light, the photographer is open to improvise in scenarios where they may not have control over the light source. Whether you shoot commercial or portrait photography, this book provides you with the basis for not only successfully, but elegantly shaping light to create your desired result.

Vascular Disruptive Agents for the Treatment of Cancer

by Tim Meyer

Tumour survival and growth is critically dependent on an independent blood supply. As such tumour vasculature presents an ideal target for cancer therapy that is widely applicable, accessible and genetically stable rendering it less prone to resistance. Two approaches have been explored for cancer therapy; firstly the prevention of new vessel formation with inhibitors of angiogenesis, and secondly the destruction of existing tumour blood vessels with so called vascular disruptive agents (VDAs). While the first approach appears to delay tumour progression, the second has the potential to cause massive cell death and tumour regression. It si the second approach of vascular targeting that is the focus of this review. Since the tubulin binding agent combretastatin, derived from the bark of the African bush willow, was discovered by George R Pettit to have antimitotic properties over twenty years ago, the field of vascular targeting has expanded steadily. Coincident with the preclinical and clinical development of these agents, there have been advances in our understanding of their mechanism of action and in the technology required to assess their effects.

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