Anita Blake works as an animator, someone who can raise zombies from the dead. As if that isn't unusual enough, she also works as a vampire hunter, trying to rid Saint Louis of those vampires that would like to do humans harm. Since the supreme court has given vampires equal rights, Anita lives in a world where the supernatural is everywhere. Most vampires are peaceful and live by the rules, but there's a few who do not, and Anita is there to stop them in their tracks. But this time Anita is given the task of keeping vampires alive. A serial killer is murdering vampires, and it's up to Anita to solve the mystery before there's another death.