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A ground-breaking and practical treatment of probability and stochastic processes A Modern Theory of Random Variation is a new and radical re-formulation of the mathematical underpinnings of subjects as diverse as investment, communication engineering, and quantum mechanics. Setting aside the classical theory of probability measure spaces, the book utilizes a mathematically rigorous version of the theory of random variation that bases itself exclusively on finitely additive probability distribution functions. In place of twentieth century Lebesgue integration and measure theory, the author uses the simpler concept of Riemann sums, and the non-absolute Riemann-type integration of Henstock. Readers are supplied with an accessible approach to standard elements of probability theory such as the central limmit theorem and Brownian motion as well as remarkable, new results on Feynman diagrams and stochastic integrals. Throughout the book, detailed numerical demonstrations accompany the discussions of abstract mathematical theory, from the simplest elements of the subject to the most complex. In addition, an array of numerical examples and vivid illustrations showcase how the presented methods and applications can be undertaken at various levels of complexity. A Modern Theory of Random Variation is a suitable book for courses on mathematical analysis, probability theory, and mathematical finance at the upper-undergraduate and graduate levels. The book is also an indispensible resource for researchers and practitioners who are seeking new concepts, techniques and methodologies in data analysis, numerical calculation, and financial asset valuation. Patrick Muldowney, PhD, served as lecturer at the Magee Business School of the UNiversity of Ulster for over twenty years. Dr. Muldowney has published extensively in his areas of research, including integration theory, financial mathematics, and random variation.
This book is an ideal resource on the subject of systems practice for busy managers whose time is scarce. It provides a rapid introduction to straightforward, yet powerful ideas that enable users to address real world problems. Systems theory and practice is predominantly a framework for thinking about the World, in which holistic views are maintained. In this respect it contrasts with some familiar techniques of management science, in which problem situations are broken down into their constituent parts with resultant loss of coherence.
Epilepsy is a common chronic neurological disorder characterised by recurrent unprovoked seizures, and affects 50 million people worldwide. Approximately 30% of these do not have seizure control even with the best available medications, hence renewed and increasing interest in the use of dietary treatments to treat epilepsy. These treatments include the traditional ketogenic diets but also the newer modified Atkins diet and low glycaemic index treatment. The ketogenic diet is a high-fat, adequate-protein, low-carbohydrate diet that in medicine is used primarily to treat refractory epilepsy in children, and requires the dedicated support of a multi-disciplinary team including doctors and dietitians. Dietary Treatment of Epilepsy: Practical Implementation of Ketogenic Therapy provides comprehensive and practical training on all aspects of implementing and managing dietary treatments for epilepsy, with key chapters on assessment, calculations, implementation, monitoring and complications. Edited by a highly respected expert in the field supported by a strong team of contributors, this is a must-have resource for paediatric dietitians and other members of the therapy team.
Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe.Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human applicationIncludes evaluation of vaccine efficacy and safetyDetails clinical trial design, including regulatory requirementsDiscusses the emerging field of active cellular immunotherapyVaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.
This is the first book primarily about the satellite payload of satellite communications systems. It represents a unique combination of practical systems engineering and communications theory. It tells about the satellites in geostationary and low-earth orbits today, both the so-called bent-pipe payloads and the processing payloads. The on-orbit environment, mitigated by the spacecraft bus, is described. The payload units (e.g. antennas and amplifiers), as well as payload-integration elements (e.g. waveguide and switches) are discussed in regard to how they work, what they do to the signal, their technology, environment sensitivity, and specifications. At a higher level are discussions on the payload as an entity: architecture including redundancy; specifications--what they mean, how they relate to unit specifications, and how to verify; and specification-compliance analysis ("budgets") with uncertainty. Aspects of probability theory handy for calculating and using uncertainty and variation are presented. The highest-level discussions, on the end-to-end communications system, start with a practical introduction to physical-layer communications theory. Atmospheric effects and interference on the communications link are described. A chapter gives an example of optimizing a multibeam payload via probabilistic analysis. Finally, practical tips on system simulation and emulation are provided. The carrier frequencies treated are 1 GHz and above. Familiarity with Fourier analysis will enhance understanding of some topics. References are provided throughout the book for readers who want to dig deeper.Payload systems engineers, payload proposal writers, satellite-communications systems designers and analysts, and satellite customers will find that the book cuts their learning time. Spacecraft-bus systems engineers, payload unit engineers, and spacecraft operators will gain insight into the overall system. Students in systems engineering, microwave engineering, communications theory, probability theory, and communications simulation and modelling will find examples to supplement theoretical texts.
Praise for the First Edition"The attention to detail is impressive. The book is very well written and the author is extremely careful with his descriptions . . . the examples are wonderful." --The American StatisticianFully revised to reflect the latest methodologies and emerging applications, Applied Regression Modeling, Second Edition continues to highlight the benefits of statistical methods, specifically regression analysis and modeling, for understanding, analyzing, and interpreting multivariate data in business, science, and social science applications.The author utilizes a bounty of real-life examples, case studies, illustrations, and graphics to introduce readers to the world of regression analysis using various software packages, including R, SPSS, Minitab, SAS, JMP, and S-PLUS. In a clear and careful writing style, the book introduces modeling extensions that illustrate more advanced regression techniques, including logistic regression, Poisson regression, discrete choice models, multilevel models, and Bayesian modeling.In addition, the Second Edition features clarification and expansion of challenging topics, such as:Transformations, indicator variables, and interactionTesting model assumptionsNonconstant varianceAutocorrelationVariable selection methodsModel building and graphical interpretationThroughout the book, datasets and examples have been updated and additional problems are included at the end of each chapter, allowing readers to test their comprehension of the presented material. In addition, a related website features the book's datasets, presentation slides, detailed statistical software instructions, and learning resources including additional problems and instructional videos.With an intuitive approach that is not heavy on mathematical detail, Applied Regression Modeling, Second Edition is an excellent book for courses on statistical regression analysis at the upper-undergraduate and graduate level. The book also serves as a valuable resource for professionals and researchers who utilize statistical methods for decision-making in their everyday work.
Mobility Models for Next Generation Wireless Networks: Ad Hoc, Vehicular and Mesh Networks provides the reader with an overview of mobility modelling, encompassing both theoretical and practical aspects related to the challenging mobility modelling task. It also:Provides up-to-date coverage of mobility models for next generation wireless networksOffers an in-depth discussion of the most representative mobility models for major next generation wireless network application scenarios, including WLAN/mesh networks, vehicular networks, wireless sensor networks, and opportunistic networksDemonstrates the practices for designing effective protocol/applications for next generation wireless networksIncludes case studies showcasing the importance of properly understanding fundamental mobility model properties in wireless network performance evaluation
Clinical Pharmacology and Therapeutics Lecture Notes provides a clear and accessible overview of all the key prescribing topics needed for medical finals and beyond. Detailed coverage and discussion of pharmacology in a clinical context, combined with an easy-to-understand, readable style, helps improve and test understanding of pharmacological principles and reasoning on rotation and into the foundation years.Key features for this edition include:* Clinical scenarios to root each chapter firmly in a real-life setting* Prescribing points flagging up important issues of clinical relevance* Expanded sections on drugs you may need in a hurry, prescribing and its pitfalls, and paediatric prescribing* A self-assessment section to test your knowledge and help prepare for examinations Clinical Pharmacology and Therapeutics Lecture Notes is an ideal resource for all medical students, junior doctors, and other prescribers, whether learning how pharmacological principles relate to clinical situations, brushing up on the basics while on rotation, or looking for a comprehensive overview of prescribing and therapeutics.
Textbook of Pharmacoepidemiology, Second Edition, provides an introduction to pharmacoepidemiology and the methodologies, data sources and applications used in clinical practice, the pharmaceutical industry and regulatory agencies. This second edition includes new and updated learning features, case examples and key points, as well as information on the new pharmacoepidemiology databases and how to use them.
This comprehensively updated new edition provides a thorough and dynamically-illustrated overview of the female reproductive organs, care of the female during pregnancy, childbirth and the postnatal period. It is clinically relevant, with a focus on diagnosing, managing and treating disorders and abnormalities and is fully aligned with medical school curricula.Obstetrics and Gynecology at a Glance:* Recaps basic history taking, anatomy and endocrinology and focuses on clinically relevant information* Covers each topic in a double-page spread, packed with charts, graphs, photographs and visuals* Includes thoroughly updated sections on reproductive endocrinology, infertility and urogynecologyThe companion website at www.ataglanceseries.com/obgyn features interactive flashcards, case studies and multiple-choice questions (MCQs).Obstetrics and Gynecology at a Glance is the perfect guide for medical students, junior doctors and midwives, and is ideal for those embarking on clinical rotations and the clerkship.
Management of Pregnant and Neonatal Dogs, Cats, and Exotic Pets is a comprehensive yet practical reference on small animal neonatology. Covering reproductive physiology of pregnancy and parturition, normal neonatology, and neonatal disorders in dogs, cats, and small exotic mammals, the book gives special emphasis to fetal well-being, parturition, normal physical parameters, behavior, common disorders and defects, emergency care, and orphan management. Information on nutritional and environmental considerations for both the dam and offspring is included, as well as guidance on offering advice to breeders providing neonatal care at home.Well illustrated throughout, Management of Pregnant and Neonatal Dogs, Cats, and Exotic Pets is a complete resource for the successful management of pregnant and newborn pets. Veterinary practitioners, students, technicians, and professional breeders all will find the book's how-to, clinically relevant approach to small animal neonatology invaluable.
Mediterranean mountains exhibit many similarities in their biotic ecological, physical and environmental characteristics. There are also many differences in terms of their human colonization pattern, historic land uses and current anthopogenic pressures. This book provides an introduction to these environments of mountainous areas in the Mediterranean and their changes in time and space in relation to both natural and cultural factors.Mediterranean Mountain Environments places its emphasis on physical geography while adopting an integrated approach to the whole subject area. The book draws examples from a wide range of environments, demonstrating the interaction between human and physical processes responsible for shaping mountain areas. Risks and conflicts, as well as methods and tools for the conservation and management of both the natural and cultural environment are covered in the light of future challenges for the sustainable development of the Mediterranean mountains.Emphasis on both mainland and island mountain rangesCombines natural and cultural approach in the topicIntegrated approach: facing future challenges based on the study and understanding of the historical processes that have shaped the Mediterranean mountainsKey references at the end of each chapter
A comprehensive guide to understanding and auditing modern information systemsThe increased dependence on information system resources for performing key activities within organizations has made system audits essential for ensuring the confidentiality, integrity, and availability of information system resources. One of the biggest challenges faced by auditors is the lack of a standardized approach and relevant checklist. Understanding and Conducting Information Systems Auditing brings together resources with audit tools and techniques to solve this problem.Featuring examples that are globally applicable and covering all major standards, the book takes a non-technical approach to the subject and presents information systems as a management tool with practical applications. It explains in detail how to conduct information systems audits and provides all the tools and checklists needed to do so. In addition, it also introduces the concept of information security grading, to help readers to implement practical changes and solutions in their organizations.Includes everything needed to perform information systems auditsOrganized into two sections--the first designed to help readers develop the understanding necessary for conducting information systems audits and the second providing checklists for auditsFeatures examples designed to appeal to a global audienceTaking a non-technical approach that makes it accessible to readers of all backgrounds, Understanding and Conducting Information Systems Auditing is an essential resource for anyone auditing information systems.
An illustrated, easy-to-read guide to advanced options tradingIn Getting Started in Advanced Options, Illustrated Edition, bestselling author Michael C. Thomsett uses nontechnical, easy-to-follow language to demystify the options markets, distinguishing the imagined risks from the real ones and arming investors with the facts they need to make more informed decisions. This illustrated edition includes colourful illustrations, including charts and graphs that make complex subject matter easy to understand. Fully updated to cover the latest changes in the markets, the book introduces advanced strategies and concepts that every successful trader needs. It covers how options can reduce risk, spread strategies, hedges and straddles, swing trading with options, options on futures and indexes, synthetic positions based on options, risks and taxes, choosing stocks for options trading, and more.An ideal illustrated companion volume to Michael C. Thomsett's Getting Started in Advanced OptionsUpdated to include the latest changes and newest information on the marketsLoaded with easy-to-understand graphs, charts, and other illustrationsThis new illustrated addition to the Getting Started In series makes advanced options trading easy to understand with clear examples, handy illustrations, and plain-English explanations.
The Hunt for the Parathyroid Gland is a part fact, part fiction overview of the discovery of the parathyroid gland by a Swedish scientist in 1880.The discovery of the parathyroid gland in humans in 1880 by an unknown Swedish medical student, Ivar Viktor Sandström, ended a 30 year search for its exact location within the human body, following its discovery in an Indian rhino 30 years before. It is one of the most engaging and remarkable stories in the history of medicine. This book offers a fascinating insight into its discovery.Endocrinologists and ENT health professionals, both in clinical practice and researchers, as well as anyone with an interest in the history of medicine, will find this a fascinating insight into one of the 19th century's key medical discoveries.
Optical waveguides take a prominent role in photonics because they are able to trap and to transport light efficiently between a point of excitation and a point of detection. Moreover, waveguides allow the management of many of the fundamental properties of light and allow highly controlled interaction with other optical systems. For this reason waveguides are ubiquitous in telecommunications, sensing, spectroscopy, light sources, and high power light delivery. Nanostructured and subwavelength waveguides have additional advantages; they are able to confine light at a length scale below the diffraction limit and enhance or suppress light-matter interaction, as well as manage fundamental properties of light such as speed and direction of energy and phase propagation.This book presents semi-analytical theory and practical applications of a large number of subwavelength and nanostructured optical waveguides and fibers operating in various regions of the electromagnetic spectrum including visible, near and mid-IR and THz. A large number of approximate, while highly precise analytical expressions are derived that describe various modal properties of the planar and circular isotropic, anisotropic, and metamaterial waveguides and fibers, as well as surface waves propagating on planar, and circular interfaces. A variety of naturally occurring and artificial materials are also considered such as dielectrics, metals, polar materials, anisotropic all-dielectric and metal-dielectric metamaterials.Contents are organized around four major themes:Guidance properties of subwavelength waveguides and fibers made of homogeneous, generally anisotropic materials Guidance properties of nanostructured waveguides and fibers using both exact geometry modelling and effective medium approximationDevelopment of the effective medium approximations for various 1D and 2D nanostructured materials and extension of these approximations to shorter wavelengthsPractical applications of subwavelength and nanostructured waveguides and fibers Nanostructured Subwavelengths and Waveguides is unique in that it collects in a single place an extensive range of analytical solutions which are derived in various limits for many practically important and popular waveguide and fiber geometries and materials.
Superconductivity is a quantum phenomenon that manifests itself in materials showing zero electrical resistance below a characteristic temperature resulting in the potential for an electric current to run continually through such a material without the need for a power source. Such materials are used extensively in medical and power applications, e.g. MRI and NMR machines. Discovering Superconductivity uses a series of practical and investigative activities, which can be used as tutor demonstrations or as student lab exercises. This highly illustrated text features the following sections: Introduction - including a brief history of superconductivitySuperconductivity - an explanation of the phenomenon and its effectsSuperconducting materials - including High & Low temperature superconductorsApplications - how superconductivity is used in medical imaging, at CERN and in the Maglev trainsThis text will serve as an excellent introduction for students, with or without a physics background, to superconductivity. With a strong practical, experimental emphasis, it provides readers with an overview of the topic preparing them for more advanced texts used in advanced undergraduate and post-graduate courses. PowerPoint files of the figures presented within this text are available at: http://booksupport.wiley.comA word from the author: "The intention of this text is to introduce the reader to the study of superconductivity via a minds-on approach......... The minds-on approach takes this a stage further by requiring the learner to engage with the process to a greater extent."
Beautifully illustrated throughout, Ophthalmology Lecture Notes concentrates on the most common eye problems that health practitioners are expected to diagnose and manage.The book begins with a brief introduction to ocular anatomy and eye examination, and then focuses on core conditions in ophthalmology. The highly structured text includes self assessment material at the end of each chapter, as well as a series of clinical cases at the end of the book - all designed to facilitate easy access to information, making the book an ideal resource for both study and revision, while the brand new companion website at www.wiley.com/go/james/ophthalmology features all of the book's illustrations and images.Whether you need to develop your knowledge for clinical practice, or refresh that knowledge in the run up to examinations, Ophthalmology Lecture Notes will help foster a systematic approach to the clinical situation for all medical students and hospital doctors.
This Second Edition of the go-to reference combines the classical analysis and modern applications of applied mathematics for chemical engineers. The book introduces traditional techniques for solving ordinary differential equations (ODEs), adding new material on approximate solution methods such as perturbation techniques and elementary numerical solutions. It also includes analytical methods to deal with important classes of finite-difference equations. The last half discusses numerical solution techniques and partial differential equations (PDEs). The reader will then be equipped to apply mathematics in the formulation of problems in chemical engineering. Like the first edition, there are many examples provided as homework and worked examples.
Search has changed everything. Has your business harnessed its full potential?A business's search strategy can have a dramatic impact on how consumers interact with that business. But even more importantly, search engine activity provides amazingly useful data about customer behavior, needs, and motivations. In this non-technical book for executives, business owners, and marketers, search engine strategy guru Vanessa Fox--who created Google's portal for site owners, Google Webmaster Central--explains what every marketer or business owner needs to understand about search rankings, search data, comprehensive search strategies, and integrating your strategy into the businesses processes.Updated statistics, tools, and recommendations Details about the latest changes from Google, Bing, and the overall search landscapeExplanation and recommendations related to Google's substantial new search algorithm, know as "Panda"Discussion of the changing landscape of the integration of search and social media, including the addition of Google+ to the mixTraditional marketing isn't enough anymore. Businesses need to evolve as customer behavior evolves. Marketing in the Age of Google shows you how.
All the latest tools needed to plan and perform the synthesis of complex bioactive moleculesFocusing on organic, organometallic, and bio-oriented processes, this book explores the impact and use of the latest synthetic tools for the synthesis of complex biologically active compounds. Readers will discover step by step how these synthetic tools have provided new, elegant solutions to many synthetic puzzles. Moreover, they will discover innovative methods that make it possible to control the exact connectivity of atoms within a molecule in order to set precise three-dimensional arrangements.Modern Tools for the Synthesis of Complex Bioactive Molecules features sixteen chapters, each one written by one or more leading experts in organic synthesis from around the world. It covers a broad range of topics that enable readers to take advantage of the latest methods for synthesizing complex molecules, including:Modern catalysis, emphasizing key transformations such as C-H functionalizations, cross-couplings, gold-catalyzed reactions, metathesis-based syntheses, and asymmetric organocatalysisEco-compatible transformations, including rearrangements and domino reactionsTools for the synthesis of carbohydrates and alkaloidsNew techniques, including the use of fluorous tags and engineered biosynthesisThe last two chapters explore target- and diversity-oriented organic synthesis as well as the use of DNA-based asymmetric catalysis, which are all promising tools for the successful synthesis of complex bioactive molecules.Modern Tools for the Synthesis of Complex Bioactive Molecules is ideal for students and researchers who need to plan and perform the synthesis of complex molecules as efficiently as possible. The book's expert advice will help these readers quickly resolve a broad range of problems that can arise in organic syntheses.
Drawing on major research developments in the field, Vihman has updated and extensively revised the 1996 edition of her classic text to provide a thorough and stimulating overview of current studies of child production and perception and early word learning.Offers a full survey of the thinking on how babies develop phonological knowledgeProvides a much needed update on the field - one in which this book remains unique, and in which there have also been dramatic developments since the publication of the first editionSurveys what has been learned about phonological development and raises questions for further studyThe only book that includes balanced treatment of research in perception and production and attempts a synthesis of these fields, which have generally developed in isolation from one anotherIncludes a new chapter providing an overview of communicative and attentional development, as well as perceptual and vocal development, in the first 18 months, with additional focus on both implicit and explicit learning mechanisms
Discover the inventions that have made our world what it is todayA great invention opens the door to a new era in human history. The stone axe, for example, invented some 2 million years ago in East Africa, enabled us to enter the human path of endless improvements through inventions. The taming of fire enabled us to cook food as well as leave the warmth of Africa and move to the frigid lands of the North. From the stone axe to the computer and the Internet, this book provides a fascinating tour of the most important inventions and inventors throughout history. You'll discover the landmark achievements and the men and women that made the world what it is today.Great Inventions That Changed the World is written by Professor James Wei, a renowned educator and engineer who holds several patents for his own inventions. Following an introductory chapter examining the role of inventors and inventions in fueling innovation and global advancement, the book is organized to show how inventions are spurred by human needs and desires, including:WorkFood, clothing, and housingHealth and reproductionSecurity As you progress through the book, you'll not only learn about inventions and inventors, but also the impact they have had on our lives and the society and environment in which we live today. Inventions solve problems, but as this book so expertly demonstrates, they can also directly or indirectly create new problems as well, from pollution to global warming to bioterrorism. By enabling us to understand the impact of inventions throughout history, this book can help guide the next generation of citizens, decision makers, and inventors.
Sustainable Healthcare sets out a vision for medical care of high quality, manageable cost and low impact on the planetary systems which sustain us.In tackling the major challenges of our age, such as resource depletion, loss of biodiversity and climate change, health services can play a central role, moving from being part of the problem to becoming part of the solution. Sustainable Healthcare explores questions such as:What is the relevance of sustainability in healthcare?How does climate change threaten human health?How can we create low carbon care pathways?How can healthcare organizations deal better with their waste?How can death and dying become more sustainable?How can we engage ourselves and others with this agenda?Written by an international team combining clinical, educational, practical and policy expertise in sustainability and health, this book provides a synopsis of our current predicaments, and explores some of the emerging solutions. Containing case studies and resources for further information and action, Sustainable Healthcare is a practical guide to making healthcare more sustainable for all healthcare professionals, managers and students."Once in a while one comes across a book that makes a deep impact. Sustainable Healthcare is such a book and very timely in the context of modern healthcare and developing green policies... The book is clear in ideas of critical thinking, scientific evidence and practical suggestions for transformative action... An additional strength in this book are the summary key papers and reports including key points from the chapters. In addition, there is a comprehensive list of references in each chapter... The authors cut through the jargon and challenge the rhetoric of both fear and denial... The authors give examples of how we can engage with sustainability such as, diet and exercise, prescription management, contraception management and family planning and end of life care... The book provides useful sources, references and key actions for individuals, healthcare organisations and policy making departments." - A review by Prof Davinder Sandhu, Postgraduate Dean, Health Education South West, Severn Deanery, UK
Psychobiological Approaches for Anxiety Disorders presents a comprehensive overview of the latest empirical evidence and research results on combining pharmacological agents and CBT techniques for the treatment of anxiety disorders.The first book to focus on the issue of enhancing CBT with pharmacological agents Features chapters from leading authors in the fields of psychiatry, pharmacology, clinical psychology, neuroscience, and emotion researchContributes significantly to the field by summarizing the contemporary research in combination treatments in anxiety disordersA valuable resource for clinicians in training, as well as experienced clinicians seeking to help patients with anxiety disorders