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Computational Neuroscience

by Panos M. Pardalos Petros Xanthopoulos Wanpracha Chaovalitwongse

This volume includes contributions from diverse disciplines including electrical engineering, biomedical engineering, industrial engineering, and medicine, bridging a vital gap between the mathematical sciences and neuroscience research. Covering a wide range of research topics, this volume demonstrates how various methods from data mining, signal processing, optimization and cutting-edge medical techniques can be used to tackle the most challenging problems in modern neuroscience.

Sensors: Theory, Algorithms, and Applications

by Panos M. Pardalos Vladimir L. Boginski Yinyu Ye Clayton W. Commander

The objective of this book is to advance the current knowledge of sensor research particularly highlighting recent advances, current work, and future needs. The goal is to share current technologies and steer future efforts in directions that will benefit the majority of researchers and practitioners working in this broad field of study.

Atlas of Implantable Therapies for Pain Management

by Timothy R Deer

This Atlas serves as a guide to beginning implanters, intermediate implanters, and the most advanced practitioners. The author covers the process of implanting and managing spinal cord stimulators, peripheral nerve stimulators, and intrathecal pumps from the beginning of the process to long term management. The book also discusses the recognition, prevention, and management of complications. The Atlas is a must for any physician hoping to improve their skills in any segment of this important area of interventional pain treatment. The combination of instructional photographs and detailed instructions makes each segment a great learning event.

Practical Handbook of Thoracic Anesthesia

by Philip M. Hartigan

This comprehensive handbook delivers "bottom line," evidence-based guidance in the practice of thoracic anesthesia. Chapters are short and practical and include actionable technical pearls not available elsewhere. The editor and contributors are academic faculty who work at one of the busiest thoracic surgical programs in North America, and their aim has been to integrate essential concepts with practical decision-making. *Detailed guidance for performing more than 30 thoracic surgical procedures *Relevant surgical insights from a senior thoracic surgeon included for each procedure *Full range of modern thoracic anesthetic challenges covered *Essential foundation concepts digested and simplified *Technical aspects sufficiently detailed to be useful *An efficient resource for skilled generalists and trainees

Traumatic Brain Injury

by Jack W. Tsao

Traumatic brain injury (TBI) is a major cause of disability worldwide. Each year 1.7 million new TBIs occur in the United States, and it is also considered a signature injury of the Iraq and Afghanistan conflicts. Despite the relatively high incidence-within both civilian and military populations-the diagnosis and treatment, particularly of mild TBI/concussion, remains an inexact science. Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation is a concise guide designed for neurologists, primary care, and sports physicians and other medical providers, psychologists and neuropsychologists, and athletic trainers who may evaluate and care for patients with TBI. The book features summaries of the most pertinent areas of diagnosis and therapy, which can be readily accessed by the busy clinician/professional. In addition, the book's treatment algorithms provide a highly practical reference to cutting edge therapies. A superb contribution to the literature, Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation offers a well-designed, well-written, useful resource for all providers who treat patients with TBI.

American Hungers

by Gavin Jones

Social anxiety about poverty surfaces with startling frequency in American literature. Yet, as Gavin Jones argues, poverty has been denied its due as a critical and ideological framework in its own right, despite recent interest in representations of the lower classes and the marginalized. These insights lay the groundwork for American Hungers, in which Jones uncovers a complex and controversial discourse on the poor that stretches from the antebellum era through the Depression. Reading writers such as Herman Melville, Theodore Dreiser, Edith Wharton, James Agee, and Richard Wright in their historical contexts, Jones explores why they succeeded where literary critics have fallen short. These authors acknowledged a poverty that was as aesthetically and culturally significant as it was socially and materially real. They confronted the ideological dilemmas of approaching poverty while giving language to the marginalized poor--the beggars, tramps, sharecroppers, and factory workers who form a persistent segment of American society. Far from peripheral, poverty emerges at the center of national debates about social justice, citizenship, and minority identity. And literature becomes a crucial tool to understand an economic and cultural condition that is at once urgent and elusive because it cuts across the categories of race, gender, and class by which we conventionally understand social difference. Combining social theory with literary analysis, American Hungers masterfully brings poverty into the mainstream critical idiom.

Theory of Stochastic Processes

by Dmytro Gusak Andrey Pilipenko Alexander Kukush Yuliya Mishura Alexey Kulik

This book is a collection of exercises covering all the main topics in the modern theory of stochastic processes and its applications, including finance, actuarial mathematics, queuing theory, and risk theory. The aim of this book is to provide the reader with the theoretical and practical material necessary for deeper understanding of the main topics in the theory of stochastic processes and its related fields. The book is divided into chapters according to the various topics. Each chapter contains problems, hints, solutions, as well as a self-contained theoretical part which gives all the necessary material for solving the problems. References to the literature are also given. The exercises have various levels of complexity and vary from simple ones, useful for students studying basic notions and technique, to very advanced ones that reveal some important theoretical facts and constructions. This book is one of the largest collections of problems in the theory of stochastic processes and its applications. The problems in this book can be useful for undergraduate and graduate students, as well as for specialists in the theory of stochastic processes.

Implicit Functions and Solution Mappings

by R. Tyrrell Rockafellar Assen L. Dontchev

The implicit function theorem is one of the most important theorems in analysis and its many variants are basic tools in partial differential equations and numerical analysis. This book treats the implicit function paradigm in the classical framework and beyond, focusing largely on properties of solution mappings of variational problems. The purpose of this self-contained work is to provide a reference on the topic and to provide a unified collection of a number of results which are currently scattered throughout the literature. The first chapter of the book treats the classical implicit function theorem in a way that will be useful for students and teachers of undergraduate calculus. The remaining part becomes gradually more advanced, and considers implicit mappings defined by relations other than equations, e.g., variational problems. Applications to numerical analysis and optimization are also provided. This valuable book is a major achievement and is sure to become a standard reference on the topic.

Mathematical Foundations of Neuroscience

by David H. Terman G. Bard Ermentrout

This book applies methods from nonlinear dynamics to problems in neuroscience. It uses modern mathematical approaches to understand patterns of neuronal activity seen in experiments and models of neuronal behavior. The intended audience is researchers interested in applying mathematics to important problems in neuroscience, and neuroscientists who would like to understand how to create models, as well as the mathematical and computational methods for analyzing them. The authors take a very broad approach and use many different methods to solve and understand complex models of neurons and circuits. They explain and combine numerical, analytical, dynamical systems and perturbation methods to produce a modern approach to the types of model equations that arise in neuroscience. There are extensive chapters on the role of noise, multiple time scales and spatial interactions in generating complex activity patterns found in experiments. The early chapters require little more than basic calculus and some elementary differential equations and can form the core of a computational neuroscience course. Later chapters can be used as a basis for a graduate class and as a source for current research in mathematical neuroscience. The book contains a large number of illustrations, chapter summaries and hundreds of exercises which are motivated by issues that arise in biology, and involve both computation and analysis. Bard Ermentrout is Professor of Computational Biology and Professor of Mathematics at the University of Pittsburgh. David Terman is Professor of Mathematics at the Ohio State University. "This excellent 422 page hardcover publication is an accessible and concise monograph. ... Mathematical Foundations is a timely contribution that will prove useful to mathematics graduate students and faculty interested in the application of dynamical systems theory to cellular and systems neuroscience. ... welcome addition to the pedagogical literature. ... For mathematics graduate students who are investigating the field of computational neuroscience, I would highly recommend Mathematical Foundations of Neuroscience as their first computational neuroscience text." (Gregory D. Smith, The Mathematical Association of America, December, 2010) "...it is a good substitute for a lengthy regime of abstract maths classes, but it is also well integrated into the field of neuroscience. Ermentrout and Terman's book conveys much of the advanced mathematics used in theoretical neuroscience today." (Vincent A. Billock, Nature)

Essentials of Pain Management

by Richard D. Urman Nalini Vadivelu Roberta L. Hines

This concise, evidence-based text contains essential topics important for every pain management student, trainee, and practitioner. Both acute and chronic pain management principles and techniques are discussed, while numerous case vignettes help reinforce basic concepts and improve clinical decision making. Throughout, a multidisciplinary approach to pain is stressed. Behavioral and physical therapies, plus ethical considerations, are also discussed in this indispensable guide for anyone involved in the management of pain.

Textbook of Pulmonary Vascular Disease

by Stephen L. Archer Charles A. Hales Stuart Rich Jason X. Yuan Joe G.N. Garcia John B. West

Textbook of Pulmonary Vascular Diseases combines basic scientific knowledge on the pulmonary circulatory system at levels of the molecule, cell, tissue, and organ with clinical diagnosis and treatment of pulmonary vascular diseases. State-of-the-art techniques and their potential applications in research, diagnosis, and treatment of pulmonary vascular diseases are also covered.

Observing the Messier Objects with a Small Telescope

by Philip Pugh

Observing the Messier Objects with a Small Telescope contains descriptions and photographs of the 103 Messier objects, with instructions on how to find them without a computerized telescope or even setting circles. The photographs show how the objects appear through a 127mm Maksutov (and other instruments, where applicable). The visual appearance of a Messier object is often very different from what can be imaged with the same telescope, and a special feature of this book is that it shows what you can see with a small telescope. It will also contain binocular descriptions of some objects. Messier published the final version of his catalog in 1781 (it contains 103 different objects), a catalog so good that it is still in common use today, well over two centuries later. In making a catalog of all the 'fixed' deep-sky objects that observers might confuse with comets, Messier had succeeded in listing all the major interesting deep-sky objects that today are targets for amateur astronomers. Messier's telescope (thought to be a 4-inch) was, by today's amateur standards, small. It also had rather poor optics by modern standards. Thus - and despite the fact that he was a master observer - all the things Messier saw can be found and observed by any observer using a commercial 127 mm (5-inch) telescope. Observing the Messier Objects with a Small Telescope lets the reader follow in Messier's footsteps by observing the Messier objects more or less as the great man saw them himself!

Skin of Color

by Andrew F. Alexis Victoria H. Barbosa

A concise practical guide to treatment and diagnosis of skin related disorders for skin of color patients.

Structure and Geometry of Lie Groups

by Joachim Hilgert Karl-Hermann Neeb

This self-contained text is an excellent introduction to Lie groups and their actions on manifolds. The authors start with an elementary discussion of matrix groups, followed by chapters devoted to the basic structure and representation theory of finite dimensinal Lie algebras. They then turn to global issues, demonstrating the key issue of the interplay between differential geometry and Lie theory. Special emphasis is placed on homogeneous spaces and invariant geometric structures. The last section of the book is dedicated to the structure theory of Lie groups. Particularly, they focus on maximal compact subgroups, dense subgroups, complex structures, and linearity. This text is accessible to a broad range of mathematicians and graduate students; it will be useful both as a graduate textbook and as a research reference.

Encyclopedia of Clinical Neuropsychology

by Bruce Caplan Jeffrey Kreutzer John Deluca

This encyclopedia serves as a unified, comprehensive reference for professionals involved in the diagnosis, evaluation, and rehabilitation of adult patients and children with neuropsychological disorders. It addresses psychological, psychosocial, and psychiatric aspects of an array of neurological disorders, emphasizing treatment and rehabilitation, not just assessment and diagnosis.

Bedside Procedures for the Intensivist

by Bennett P. Deboisblanc Heidi L. Frankel

Bedside Procedures for the Intensivist delivers practical tips and clear, step-by-step instruction on the most common procedures in the ICU. The convenient and portable handbook focuses on ultrasound-guided techniques, including an introduction to ultrasound physics and principles, while individual chapters provide concise "how-to" text supplemented with numerous full-color figures and tables that summarize key content. Residents, fellows, and trainees in critical care will benefit from the detailing of indications and contraindications for performing core procedures, while more experienced intensivists will find the book a reliable source of review material. Key procedures described include: * Ultrasound-guided vascular access * Ultrasound-guided drainage * Focused echocardiography * Airway management * Dialysis and apheresis * Pericardiocentesis * Insertion of vena cava filters * Percutaneous dilational tracheostomy * Open tracheostomy * Transbronchial biopsy * Percutaneous endoscopic gastrostomy * Intracranial monitoring

Carbon-based Membranes for Separation Processes

by Takeshi Matsuura Dipak Rana Ahmad Fauzi Ismail Henry C. Foley

This book provides a significant overview of carbon-related membranes. It will cover the development of carbon related membranes and membrane modules from its onset to the latest research on carbon mixed matrix membranes. After reviewing progress in the field, the authors indicate future research directions and prospective development. The authors also attempt to provide a guideline for the readers who would like to establish their own laboratories for carbon membrane research. For this purpose, detailed information on preparation, characterization and testing of various types of carbon membrane is provided. Design and construction of carbon membrane modules are also described in detail.

Handbook of Disease Burdens and Quality of Life Measures

by Victor R. Preedy Ronald R. Watson

This handbook features in-depth reviews of disability-adjusted life years (DALYs), quality-adjusted life years (QALYs), quality of life and financial measures for over 120 diseases and conditions. Its editors have organized this critical information for maximum access and ease of use, with abstracts, definitions of key terms, summary points, and dozens of figures and tables that can enhance the text or stand alone.

Safety of Nanoparticles

by Thomas J. Webster

In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.

The China Information Technology Handbook

by Miltiadis D. Lytras Patricia Ordóñez de Pablos

This handbook is a reference for those interested in information technologies and emerging management practices in China. The emphasis on information technologies and management provides a unique proposition and gives characteristics of flexibility and adoption to diverse audiences. The subject area is a combination of global information technology and management along with strategic management of IT. The handbook exploits state-of-the-art and emerging trends in theory and technology. This handbook is primarily designed for a professional and academic audience.

Critical Care Study Guide

by Gerard J. Criner Gilbert E. D'Alonzo Rodger E. Barnette

The second edition of this best-selling study guide and text covers all aspects of critical care medicine. Written by a diverse group of physicians and health care personnel, it is of interest to all professionals who care for the ICU patient. The unique format includes key points highlighted in the margins for quick reference and self-assessment questions and answers at the end of each chapter. The text is supported by case studies, tables, and numerous illustrations that detail key procedures. The new edition has been revised substantially to reflect the most current research and guidelines, and new chapters have been added to make this the most practical and comprehensive study guide and text available today.

Chance Rules

by Brian Everitt

Chance continues to govern our lives in the 21st Century. From the genes we inherit and the environment into which we are born, to the lottery ticket we buy at the local store, much of life is a gamble. In business, education, travel, health, and marriage, we take chances in the hope of obtaining something better. Chance colors our lives with uncertainty, and so it is important to examine it and try to understand about how it operates in a number of different circumstances. Such understanding becomes simpler if we take some time to learn a little about probability, since probability is the natural language of uncertainty. This second edition of Chance Rules again recounts the story of chance through history and the various ways it impacts on our lives. Here you can read about the earliest gamblers who thought that the fall of the dice was controlled by the gods, as well as the modern geneticist and quantum theory researcher trying to integrate aspects of probability into their chosen speciality. Example included in the first addition such as the infamous Monty Hall problem, tossing coins, coincidences, horse racing, birthdays and babies remain, often with an expanded discussion, in this edition. Additional material in the second edition includes, a probabilistic explanation of why things were better when you were younger, consideration of whether you can use probability to prove the existence of God, how long you may have to wait to win the lottery, some court room dramas, predicting the future, and how evolution scores over creationism. Chance Rules lets you learn about probability without complex mathematics.

Chemical Communication in Crustaceans

by Thomas Breithaupt Martin Thiel

The crustaceans are ecologically and economically important organisms. They constitute one of the dominant invertebrate groups on earth, particularly within the aquatic realm. Crustaceans include some of the preferred scientific model organism, profitable aquaculture specimen, but also invasive nuisance species threatening native animal communities throughout the world. Chemoreception is the most important sensory modality of crustaceans, acquiring important information about their environment and picking up the chemical signals that mediate communication with conspecifics. Significant advances have been made in our understanding of crustacean chemical communication during the past decade. This includes knowledge about the identity, production, transfer, reception and behavioral function of chemical signals in selected crustacean groups. While it is well known that chemical communication is an integral part of the behavioral ecology of most living organisms, the intricate ways in which organisms allocate chemicals in communication remains enigmatic. How does the environment influence the evolution of chemical communication? What are the environmental cues that induce production or release of chemicals? How do individuals economize production and utilization of chemicals? What is the importance of molecule specificity or mix of a molecule cocktail in chemical communication? What is the role of chemical cues in multimodal communication? How does the ontogenetic stage, the sex or the physiological status of an individual affect its reaction to chemical cues? Many of these questions still represent important challenges to biologists.

The Little Black Book of Neuropsychology

by Mike R. Schoenberg James G. Scott

From translating the patient's medical records and test results to providing recommendations, the neuropsychological evaluation incorporates the science and practice of neuropsychology, neurology, and psychological sciences. The Little Black Book of Neuropsychology brings the practice and study of neuropsychology into concise step-by-step focus--without skimping on scientific quality. This one-of-a-kind assessment reference complements standard textbooks by outlining signs, symptoms, and complaints according to neuropsychological domain (such as memory, language, or executive function), with descriptions of possible deficits involved, inpatient and outpatient assessment methods, and possible etiologies. Additional chapters offer a more traditional approach to evaluation, discussing specific neurological disorders and diseases in terms of their clinical features, neuroanatomical correlates, and assessment and treatment considerations. Chapters in psychometrics provide for initial understanding of brain-behavior interpretation as well as more advanced principals for neuropsychology practice including new diagnostic concepts and analysis of change in performance over time. For the trainee, beginning clinician or seasoned expert, this user-friendly presentation incorporating 'quick reference guides' throughout which will add to the practice armentarium of beginning and seasoned clinicians alike. Key features of The Black Book of Neuropsychology: Concise framework for understanding the neuropsychological referral. Symptoms/syndromes presented in a handy outline format, with dozens of charts and tables. Review of basic neurobehavioral examination procedure. Attention to professional issues, including advances in psychometrics and diagnoses, including tables for reliable change for many commonly used tests. Special "Writing Reports like You Mean It" section and guidelines for answering referral questions.Includes appendices of practical information, including neuropsychological formulary. The Little Black Book of Neuropsychology is an indispensable resource for the range of practitioners and scientists interested in brain-behavior relationships. Particular emphasis is provided for trainees in neuropsychology and neuropsychologists. However, the easy to use format and concise presentation is likely to be of particular value to interns, residents, and fellows studying neurology, neurological surgery, psychiatry, and nurses. Finally, teachers of neuropsychological and neurological assessment may also find this book useful as a classroom text. "There is no other book in the field that covers the scope of material that is inside this comprehensive text. The work might be best summed up as being a clinical neuropsychology postdoctoral residency in a book, with the most up to date information available, so that it is also an indispensible book for practicing neuropsychologists in addition to students and residents...There is really no book like this available today. It skillfully brings together the most important foundationsof clinical neuropsychology with the 'nuts and bolts' of every facet of assessment. It also reminds the more weathered neuropsychologists among us of the essential value of neuropsychological assessment...the impact of the disease on the patient's cognitive functioning and behavior may only be objectively quantified through a neuropsychological assessment." Arch Clin Neuropsychol (2011) first published online June 13, 2011 Read the full review acn.oxfordjournals.org

Combinatorial Computational Biology of RNA

by Christian Reidys

In this monograph, new combinatorial and computational approaches in the study of RNA structures are presented which enhance both mathematics and computational biology. It begins with an introductory chapter, which motivates and sets the background of this research. In the following chapter, all the concepts are systematically developed. The reader will find * integration of more than forty research papers covering topics like, RSK-algorithm, reflection principle, singularity analysis and random graph theory * systematic presentation of the theory of pseudo-knotted RNA structures including their generating function, uniform generation as well as central and discrete limit theorems * computational biology of pseudo-knotted RNA structures, including dynamic programming paradigms and a new folding algorithm * analysis of neutral networks of pseudo knotted RNA structures and their random graph theory, including neutral paths, giant components and connectivity All algorithms presented are freely available through springer.com and implemented in C. A proofs section at the end contains the necessary technicalities. This book will serve graduate students and researchers in the fields of discrete mathematics, mathematical and computational biology. It is suitable as a textbook for a graduate course in mathematical and computational biology.

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