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The book addresses the problems that couples experience through the life cycle. Each chapter includes an up-to-date review of the literature pertinent to the topic, with a focus on practical interventions which are generally based upon, but not limited to, cognitive and rational emotive behavioral principles. Case studies or vignettes further illustrate application of principles. Worksheets, checklists, or other resources that would be useful in working with couples are also included where relevant. This book presents interventions based upon research, theory, and most of all on practice. And is relevant to marriage and family therapists, mental health counselors, psychologists and psychiatrists, nurse practitioners, family law experts, social workers and relationship coaches. In addition, it can serve as a textbook for students in marriage and family therapy.
This volume is a collection of research surveys on the Distance Geometry Problem (DGP) and its applications. It will be divided into three parts: Theory, Methods and Applications. Each part will contain at least one survey and several research papers. The first part, Theory, will deal with theoretical aspects of the DGP, including a new class of problems and the study of its complexities as well as the relation between DGP and other related topics, such as: distance matrix theory, Euclidean distance matrix completion problem, multispherical structure of distance matrices, distance geometry and geometric algebra, algebraic distance geometry theory, visualization of K-dimensional structures in the plane, graph rigidity, and theory of discretizable DGP: symmetry and complexity. The second part, Methods, will discuss mathematical and computational properties of methods developed to the problems considered in the first chapter including continuous methods (based on Gaussian and hyperbolic smoothing, difference of convex functions, semidefinite programming, branch-and-bound), discrete methods (based on branch-and-prune, geometric build-up, graph rigidity), and also heuristics methods (based on simulated annealing, genetic algorithms, tabu search, variable neighborhood search). Applications will comprise the third part and will consider applications of DGP to NMR structure calculation, rational drug design, molecular dynamics simulations, graph drawing and sensor network localization. This volume will be the first edited book on distance geometry and applications. The editors are in correspondence with the major contributors to the field of distance geometry, including important research centers in molecular biology such as Institut Pasteur in Paris.
Over the past two decades, the face of the world consumer has truly changed. Goods are more available, information about these goods is more open and accessible, and the ability to buy these goods from any corner of the earth has become possible. As a result, international marketing is more important now than ever before. In this book, Josh Samli explores the challenges facing modern international marketers. He explains what it is to have successful communication with the target market: using social media to share consistent information about products and services, communicating directly with culture-driven consumers who already communicate online amongst themselves and with competitors, and mastering people-to-people communication with both privileged and non-privileged consumers. Any company dealing with international marketing must learn how to handle these new challenges in order to survive in the 21st century.
Breast cancer is the most common malignancy among the female population. With advances in systemic therapies and modern radiotherapy techniques, breast cancer patients can have a long life-expectancy. However, it is crucial that radiation therapy is carried out with minimum complications and with the utmost efficiency. Principles and Practice of Modern Radiotherapy Techniques in Breast Cancer provides practical and current theoretical knowledge to the planning and implementation of breast cancer radiation therapy. All aspects of breast cancer are covered, including epidemiology, molecular and biological basis and integrating systemic therapies during all steps of treatment. The illustrated section of this book identifies anatomical structures in daily practice by presenting target and critical structures in actual treatment positions. These images show and mark the anatomical points of the patient lying in the position that breast radiation therapy would be performed. This text serves as a valuable resource for clinicians, residents and fellows practicing and learning breast cancer radiotherapy.
The wide-ranging scope of the Handbook of Life-Course Criminology covers genetics and environment, child offenders and late bloomers, the impact of school and peers, lifelong and time-limited criminal careers, and qualitative and quantitative methodologies. This unique Handbook is further set apart by its dual coverage of the leading edge of current research and innovative directions for future work in the field. Pathways to crime have been a central concept of criminology from its inception. Accordingly, a lifespan approach to the field has replaced earlier biological and sociological perspectives with a more nuanced understanding of offender behavior and a wider lens of study. The contributions to this Handbook break down issues of criminal and antisocial behavior from early childhood to late adulthood, examining developmentally targeted prevention and intervention strategies and reviewing emerging trends in research. Among the topics: · Childhood: including physical aggression in childhood, pre- and peri-natal development, and environment. · Adolescence: the impact of schooling, unstructured time with peers, gang membership and peer networks. · Adulthood: Adult onset crime, unemployment in emerging adulthood, crime and adult outcomes. · Prevention and Intervention: community programs, lifetime intervention strategies, re-entry. This volume will be a valuable piece for researchers in Criminology and Criminal Justice as well as related disciplines such as Sociology, Developmental Psychology, and Social Policy. It will serve as an important reference for the current state of research, as well as a roadmap for future scholars. -- "This impressive Handbook provides comprehensive coverage of key developmental and life course issues in criminology from birth to adulthood, including biology, genetics, gangs, schools, neighborhoods, adult onset, desistance, and interventions. The research recommendations in each chapter are especially important, and they should stimulate advances in knowledge for many years to come. This Handbook should be required reading for all criminologists." David P. Farrington, Professor of Psychological Criminology, Cambridge University, Cambridge, UK "In just a few decades developmental criminology has become the dominant intellectual force in criminology. This volume demonstrates why. It provides incisive reviews of important themes in developmental criminology. More importantly, it lays out rich agendas for future research that should inspire the next generation of developmental criminologists." Daniel S. Nagin, Teresa and H. John Heinz III University Professor of Public Policy and Statistics, Carnegie Melon University, Pittsburgh, PA, USA
This book highlights a neglected area in the field of rehabilitation of female offenders with AIDS. It provides data to show how women, working as HIV peer educators in prison, utilize their peer experiences as a transition point for rehabilitation both inside and outside of the penitentiary. HIV and prison are inextricably linked and education has proved to be the one constant that mitigates the spread of both HIV and crime. Research on female inmates in general is not frequent and this book presents unique qualitative data that includes rich accounts from the women themselves. It illustrates the benefits derived by female inmates who work in an HIV prison-based peer program, while adding to the criminology literature on female patterns of criminality and rehabilitation. It provides a greater understanding of how prison programs affect the processes of criminal desistance and behavioral changes for female inmates. Women involved in such programming are able to change the criminal trajectory of their life direction. contributing to reduced levels of recidivism and institutional disciplinary infractions. The implications for these programs is relevant within the broader perspective of women, HIV and incarceration.
GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chan's group in 2002. These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA degradation. The detailed biological functions of these cytoplasmic structures are still being uncovered and the idea for this book is to provide the history of the discovery and the major work from different laboratories that has led to the characterization and elucidation of the structure and function of these new multiple subcellular structures.
Bayesian Networks and Influence Diagrams: A Guide to Construction and Analysis, Second Edition, provides a comprehensive guide for practitioners who wish to understand, construct, and analyze intelligent systems for decision support based on probabilistic networks. This new edition contains six new sections, in addition to fully-updated examples, tables, figures, and a revised appendix. Intended primarily for practitioners, this book does not require sophisticated mathematical skills or deep understanding of the underlying theory and methods nor does it discuss alternative technologies for reasoning under uncertainty. The theory and methods presented are illustrated through more than 140 examples, and exercises are included for the reader to check his or her level of understanding. The techniques and methods presented for knowledge elicitation, model construction and verification, modeling techniques and tricks, learning models from data, and analyses of models have all been developed and refined on the basis of numerous courses that the authors have held for practitioners worldwide.
Ordinary people, community leaders, and even organizations and corporations still do not fully comprehend the interconnected, "big picture" dynamics of sustainability theory and action. In exploring means to become more sustainable, individuals and groups need a reference in which to frame discussions so they will be relevant, educational, and successful when implemented. This book puts ideas on sustainable communities into a conceptual framework that will promote striking, transformational effects on decision-making. In this book practitioners and community leaders will find effective, comprehensive tools and resources at their finger-tips to facilitate sustainable community development (SCD). The book content examines a diverse range of SCD methods; assessing community needs and resources; creating community visions; promoting stakeholder interest and participation; analyzing community problems; designing and facilitating strategic planning; carrying out interventions to improve
Dynamical System Synchronization (DSS) meticulously presents for the first time the theory of dynamical systems synchronization based on the local singularity theory of discontinuous dynamical systems. The book details the sufficient and necessary conditions for dynamical systems synchronizations, through extensive mathematical expression. Techniques for engineering implementation of DSS are clearly presented compared with the existing techniques.
This book presents some recent systems engineering and mathematical tools for health care along with their real-world applications by health care practitioners and engineers. Advanced approaches, tools, and algorithms used in operating room scheduling and patient flow are covered. State-of-the-art results from applications of data mining, business process modeling, and simulation in healthcare, together with optimization methods, form the core of the volume. Systems Analysis Tools for Better Health Care Delivery illustrates the increased need of partnership between engineers and health care professionals. This book will benefit researchers and practitioners in health care delivery institutions, staff members and professionals of specialized hospital units, and lecturers and graduate students in engineering, applied mathematics, business administration and health care.
Circadian rhythms are such an innate part of our lives that we rarely pause to speculate why they even exist. Some studies have suggested that the disruption of the circadian system may be causal for obesity and manifestations of Metabolic Syndrome (MetS). Shift-work, sleep-deprivation and bright-light-exposure at night are related to increased adiposity (obesity) and prevalence of MetS. It has been provided evidence of clock genes expression in human adipose tissue and demonstrated its association with different components of the MetS. Moreover, current studies are illustrating the particular role of different clock genes variants and their predicted haplotypes in MetS. The purpose of "Chronobiology and Obesity" is to describe the mechanisms implicated in the interaction between chonodisruption and metabolic-related illnesses, such as obesity and MetS, with different approaches.
This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.
Advances in digital technology led to the development of digital x-ray detectors that are currently in wide use for projection radiography, including Computed Radiography (CR) and Digital Radiography (DR). Digital Imaging Systems for Plain Radiography addresses the current technological methods available to medical imaging professionals to ensure the optimization of the radiological process concerning image quality and reduction of patient exposure. Based on extensive research by the authors and reference to the current literature, the book addresses how exposure parameters influence the diagnostic quality in digital systems, what the current acceptable radiation doses are for useful diagnostic images, and at what level the dose could be reduced to maintain an accurate diagnosis. The book is a valuable resource for both students learning the field and for imaging professionals to apply to their own practice while performing radiological examinations with digital systems.
ESA's Venus Express Mission has monitored Venus since April 2006, and scientists worldwide have used mathematical models to investigate its atmosphere and model its circulation. This book summarizes recent work to explore and understand the climate of the planet through a research program under the auspices of the International Space Science Institute (ISSI) in Bern, Switzerland. Some of the unique elements that are discussed are the anomalies with Venus' surface temperature (the huge greenhouse effect causes the surface to rise to 460°C, without which would plummet as low as -40°C), its unusual lack of solar radiation (despite being closer to the Sun, Venus receives less solar radiation than Earth due to its dense cloud cover reflecting 76% back) and the juxtaposition of its atmosphere and planetary rotation (wind speeds can climb up to 200 m/s, much faster than Venus' sidereal day of 243 Earth-days).
This volume presents a selection of survey and research articles based on invited lectures and contributed talks presented at the Workshop on Fluid Dynamics in Porous Media that was held in Coimbra, Portugal, in September 12-14, 2011. The contributions are devoted to mathematical modeling, numerical simulation and their applications, providing the readers a state-of-the-art overview on the latest findings and new challenges on the topic. The book includes research work of worldwide recognized leaders in their respective fields and presents advances in both theory and applications, making it appealing to a vast range of audience, in particular mathematicians, engineers and physicists.
Sensors: An Introductory Course provides an essential reference on the fundamentals of sensors. The book is designed to help readers in developing skills and the understanding required in order to implement a wide range of sensors that are commonly used in our daily lives. This book covers the basic concepts in the sensors field, including definitions and terminologies. The physical sensing effects are described, and devices which utilize these effects are presented. The most frequently used organic and inorganic sensors are introduced and the techniques for implementing them are discussed.
This book describes a unique approach to smart receiver system design. It starts with the analysis of a very basic, single-path receiver structure, then using similar methods, extends the analysis to a more complicated multi-path receiver. Within the multi-path structure, two different types of phased -array architectures are discussed: Analog beam-forming, and digital beam-forming. The pros and cons are studied, and the gaps are identified. Whereas previous books in this area focus mainly on phased-array circuit implementations, this book fills a gap by providing a system-level approach and introduces new methods for developing smart systems.
In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.
This book offers thorough coverage of emergencies in dermatology, from the basics of critical care for dermatologic emergencies, to neonatal and pediatric emergencies, infectious emergencies, drug eruptions and HIV-AIDS-related emergencies, among many others.
Continuum Mechanics of Anisotropic Materials(CMAM) presents an entirely new and unique development of material anisotropy in the context of an appropriate selection and organization of continuum mechanics topics. These features will distinguish this continuum mechanics book from other books on this subject. Textbooks on continuum mechanics are widely employed in engineering education, however, none of them deal specifically with anisotropy in materials. For the audience of Biomedical, Chemical and Civil Engineering students, these materials will be dealt with more frequently and greater accuracy in their analysis will be desired. Continuum Mechanics of Anisotropic Materials' author has been a leader in the field of developing new approaches for the understanding of anisotropic materials.
Mathematical Statistics for Economics and Business, Second Edition, provides a comprehensive introduction to the principles of mathematical statistics which underpin statistical analyses in the fields of economics, business, and econometrics. The selection of topics in this textbook is designed to provide students with a conceptual foundation that will facilitate a substantial understanding of statistical applications in these subjects. This new edition has been updated throughout and now also includes a downloadable Student Answer Manual containing detailed solutions to half of the over 300 end-of-chapter problems. After introducing the concepts of probability, random variables, and probability density functions, the author develops the key concepts of mathematical statistics, most notably: expectation, sampling, asymptotics, and the main families of distributions. The latter half of the book is then devoted to the theories of estimation and hypothesis testing with associated examples and problems that indicate their wide applicability in economics and business. Features of the new edition include: a reorganization of topic flow and presentation to facilitate reading and understanding; inclusion of additional topics of relevance to statistics and econometric applications; a more streamlined and simple-to-understand notation for multiple integration and multiple summation over general sets or vector arguments; updated examples; new end-of-chapter problems; a solution manual for students; a comprehensive answer manual for instructors; and a theorem and definition map. This book has evolved from numerous graduate courses in mathematical statistics and econometrics taught by the author, and will be ideal for students beginning graduate study as well as for advanced undergraduates.
Nanoscale Applications for Information and Energy Systems presents nanotechnology fundamentals and applications in the key research areas of information technology (electronics and photonics) and alternative (solar) energy: plasmonics, photovoltaics, transparent conducting electrodes, silicon electroplating, and resistive switching. The three major technology areas - electronics, photonics, and solar energy - are linked on the basis of similar applications of nanostructured materials in research and development. By bridging the materials physics and chemistry at the atomic scale with device and system design, integration, and performance requirements, tutorial chapters from worldwide leaders in the field provide a coherent picture of theoretical and experimental research efforts and technology development in these highly interdisciplinary areas.
Handbook of Endovascular Interventions presents a step-wise approach to the techniques of peripheral vascular interventions. Covering interventions in all major organ systems, this concise and comprehensive resource provides the rationale on why these approaches have been adopted by most practicing vascular interventionalists. This volume also presents key information on intervention techniques and pitfalls, complications and their management, surgical management options, as well as landmark papers on the topic. Unique to this book is the inclusion of sections building an endovascular suite, and coding as well as international training paradigms across the globe. Authored by international experts from around the globe, Handbook of Endovascular Interventions is a true how-to book for the busy interventionalist.
Many statistical innovations are linked to applications in food science. For example, the student t-test (a statistical method) was developed to monitor the quality of stout at the Guinness Brewery and multivariate statistical methods are applied widely in the spectroscopic analysis of foods. Nevertheless, statistical methods are most often associated with engineering, mathematics, and the medical sciences, and are rarely thought to be driven by food science. Consequently, there is a dearth of statistical methods aimed specifically at food science, forcing researchers to utilize methods intended for other disciplines. The objective of this Brief will be to highlight the most needed and relevant statistical methods in food science and thus eliminate the need to learn about these methods from other fields. All methods and their applications will be illustrated with examples from research literature.
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