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ith a list of suggested original research articles and reviews for further investigation of individual topics. Presenting our most current understanding of metalloproteins, Chemistry of Metalloproteins is recommended for students and researchers in coordination chemistry, biology, and medicine. Each volume of the Wiley Series in Protein and Peptide Science addresses a specific facet of the field, reviewing the latest findings and presenting a broad range of perspectives. The volumes in this series constitute essential reading for biochemists, biophysicists, molecular biologists, geneticists, cell biologists, and physiologists as well as researchers in drug design and development, proteomics, and molecular medicine with an interest in proteins and peptides.
Probabilistic Design for Optimization and Robustness: Presents the theory of modeling with variation using physical models and methods for practical applications on designs more insensitive to variation. Provides a comprehensive guide to optimization and robustness for probabilistic design. Features examples, case studies and exercises throughout. The methods presented can be applied to a wide range of disciplines such as mechanics, electrics, chemistry, aerospace, industry and engineering. This text is supported by an accompanying website featuring videos, interactive animations to aid the readers understanding.
ASP.NET MVC insiders cover the latest updates to the technology in this popular Wrox referenceMVC 5 is the newest update to the popular Microsoft technology that enables you to build dynamic, data-driven websites. Like previous versions, this guide shows you step-by-step techniques on using MVC to best advantage, with plenty of practical tutorials to illustrate the concepts. It covers controllers, views, and models; forms and HTML helpers; data annotation and validation; membership, authorization, and security.MVC 5, the latest version of MVC, adds sophisticated features such as single page applications, mobile optimization, and adaptive renderingA team of top Microsoft MVP experts, along with visionaries in the field, provide practical advice on basic and advanced MVC topicsCovers controllers, views, models, forms, data annotations, authorization and security, Ajax, routing, ASP.NET web API, dependency injection, unit testing, real-world application, and much moreProfessional ASP.NET MVC 5 is the comprehensive resource you need to make the best use of the updated Model-View-Controller technology.
Zoo Animal and Wildlife Immobilization and Anesthesia, Second Edition is a fully updated and revised version of the first comprehensive reference on anesthetic techniques in captive and free-ranging wildlife. Now including expanded coverage of avian and aquatic species, this exhaustive resource presents information on the full range of zoo and wildlife species. Covering topics ranging from monitoring and field anesthesia to CPR and euthanasia, the heart of the book is devoted to 53 species-specific chapters providing a wealth of information on little-known and common zoo and wildlife animals alike. In addition to new species chapters, the new edition brings a new focus on pain management, including chronic pain, and more information on species-specific physiology. Chapters on airway management, monitoring, emergency therapeutics, and field procedures are all significantly expanded as well. This update to Zoo Animal and Wildlife Immobilization and Anesthesia is an invaluable addition to the library of all zoo and wildlife veterinarians.
A comprehensive, accessible guide to the policies and practicesof risk management in higher education Student affairs staff at all types of colleges and universitiesneed to be equipped to help manage risk and protect theirinstitutions, the people they serve, and their resources fromunintended consequences. Risk Management in Student Affairs:Foundations for Safety and Success helps practitionersunderstand the sources of risk in their work, and the practices andstrategies they can employ to help mitigate that risk.Written for those without legal training, the book is accessibleto new and mid-level professionals as well as students preparing toenter the profession. It teaches how to limit, control, and respondto risk in order to protect oneself and one's institution. The bookcovers all aspects of risk management in higher education,including:Tort liability (such as damage due to negligence, accidents oncampus, injuries resulting from alcohol use, and incidents duringstudy-abroad trips)Contracts (such as off-campus incidents, contracts for eventsand activities, and employment and disciplinary issues)State and federal violations (including the freedoms of speech,religion, and the press, search and seizure, due process, OSHA,Title IX, FERPA, and ADA)Resource protection (including information and data security,facilities, financial resources, and physical environments)Managing risk is an integral part of the work of studentaffairs, and the ability to manage risk well can save time, money,and personnel at a time when resources can be scarce. Whether youwork in a public or private institution, and whether you managepersonal or institutional risk, no other book addresses riskmanagement within higher education in such a focused, comprehensivemanner.
The only manual for faculty and staff who work directlywith student organizations Advising Student Groups and Organizations is aone-of-a-kind book that equips faculty members and administratorsto competently and confidently serve as advisers to clubs and otherstudent groups. The second edition is here to help colleges anduniversities keep up with the skyrocketing number of student groupsand shifts in the legal landscape. New chapters on crucial topics,updated case studies, and a full suite of practical resourcessimplify the process of navigating student organizations.With Advising Student Groups and Organizations, educatorscan turn the chore of advising into a rewarding activity thatbenefits everyone. Challenges like student apathy, universitypolitics, and budgetary restrictions can be overcome with the ideasand activities presented here. And in this fully updated edition,new chapters contain everything you need to know about:Advising fraternities and sororitiesNavigating laws such as FERPA, Title IX, and the Clery ActWorking with online distance students and using social media asan advising toolConflict mediation and training student advisorsYou'll want to keep this guide handy so you can take advantageof tools like reflection questions, activities, checklists, andsample forms. Advising Student Groups and Organizations evencovers the use of assessments such as True Colors andStrengthsFinder. Now you'll be able to cut through bureaucracy tomake the student advising experience truly transformative.
Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Modelsby Jill Fiedler-Kelly Joel S. Owen
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis. * Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects * Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment * Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control * Has datasets, programming code, and practice exercises with solutions, available on a supplementary website
ABC of Anxiety and Depression is a practical guide to the assessment, treatment and management of patients with anxiety and depression as they commonly present in primary care.It begins with an introduction to views on the understanding of anxiety and depression. The following chapters cover how anxiety and depression present in different patient groups such as children and young people, adults, older people and during antenatal/postnatal periods. It then addresses anxiety and depression as comorbidities with chronic illness, and within special populations and settings.The options for treatment and management of anxiety and depression are considered with guidance on when referral to secondary care may be appropriate and the current best practice in psychological therapies, drug treatment and social interventions. Cases are used to illustrate the complexities of managing patients with anxiety and depression.The title concludes with an important chapter on practitioner well-being.ABC of Anxiety and Depression is a practical resource all general practitioners and family physicians working with patients with anxiety and depressive disorders. It is also relevant for primary health care professionals who are part of clinical teams treating patients with anxiety and depression, and conditions where anxiety and depression are common comorbidities, as well as psychologists, counsellors, social workers, and medical and nursing students.
An all-weather, tactical approach to asset management utilizingExchange Traded Funds (ETFs) In Asset Rotation, portfolio management pioneer MatthewP. Erickson demonstrates a time-tested approach to asset managementthat has worked throughout the history of capital markets, in goodtimes and bad. Providing investors with strong participation inrising markets, but more importantly with a discipline to reduceparticipation in prolonged declines. Over time this revolutionaryapproach has yielded superior returns, with significantly reducedlevels of risk; providing the engine for true, long-termsustainable growth.The investment world as we know it has changed, and the paradigmhas shifted. What has worked in the past may no longer work in thefuture. No longer may bonds be regarded as a safe haven assetclass, as for the first time in generations, investors in fixedincome face losses as interest rates rise from historical all-timelows. For those adhering to a conventional Modern Portfolio Theorybased investment approach to asset management, what was onceregarded as safe and stable, may very well soon become our greatestimpediment.Asset Rotation provides investors with a practicalsolution for today's real world problems. This tactical approach toasset management provides us with concrete proof that there isindeed a better way.We are standing on the precipice of an InvestmentRenaissance. What was previously impossible, is now possible.Find out how.Presents an easy-to-understand price momentum-based approach toinvestingIllustrates the benefits of asset rotationOffers a systematic approach for securing a sound financialfutureProvides further insights as to how to customize your own assetrotation portfolioMatthew Erickson gives investors a hands-on resource for how tonavigate an increasingly difficult investment landscape, byproviding them with keen insights into the most rapidly growingsegment of the investment markets.
Join the digital audio revolution! Tens of millions of users are embracing digital music, and with Digital Audio Essentials , you can, too. Nearly every personal computer built in the last few years contains a CD-burning drive; MP3 and other portable player sales dominate the consumer electronics industry; and new networkable stereo equipment lets you use your digital music collection to power your home entertainment system. Whether it's downloading music, ripping CDs, organizing, finding, and creating higher quality music files, buying music players and accessories, or constructing a home stereo system, Digital Audio Essentials helps you do get it done. An indispensable reference for music enthusiasts, digital archivists, amateur musicians, and anyone who likes a good groove, Digital Audio Essentials helps you avoid time-consuming, costly trial and error in downloading audio files, burning CDs, converting analog music to digital form, publishing music to and streaming from the Web, setting up home stereo configurations, and creating your own MP3 and other audio files. The book--for both Mac and PC users--includes reliable hardware and software recommendations, tutorials, resources, and file sharing, and it even explains the basics of the DMCA and intellectual property law. You may (or may not) already know the basics of ripping CDs or downloading music, but Fries will show you so much more--including advice on the multitude of MP3 players on the market, stereo options, file formats, quality determinations, and the legalities of it all. Both a timely, entertaining guide and an enduring reference, this is the digital audio handbook you need to make the most of your expanding digital music collection.
Nokia's smartphones pack a powerful computer into a very small space. Unlike your desktop or laptop, your smallest computer can be connected to the Internet all the time, and can interact with the world around it through its camera, voice recognition, and its traditional phone keypad. Nokia smartphones combine these features with impressive storage options and a host of networking protocols that make this smallest computer the only thing a road warrior truly needs. If you're still cracking open your laptop or pining for your desktop while you're on the road, you haven't begun to unlock your Nokia's full potential. Nokia Smartphone Hacks is dedicated to tricking out your smartphone and finding all the capabilities lurking under the surface. Learn how to: Unlock your phone so that you can use it with any carrier Avoid and recover from malicious mobile software Watch DVD movies on the phone Use the phone as a remote control Use the phone as a data modem for your notebook Check your email and browse the web Post to your weblog from your phone Record phone conversations Choose mobile service plans Transfer files between the phone and your computer Whether you want to use your smartphone as your lifeline while you're on the road, or you're just looking for a way to make the most of the time you spend waiting in lines, you'll find all the user-friendly tips, tools, and tricks you need to become massively productive with your Nokia smartphone. With Nokia Smartphone Hacks, you'll unleash the full power of that computer that's sitting in your pocket, purse, or backpack.
But Sony's new PlayStation Portable PSP)isn't just a handheld gaming device. Beyond its killer graphics and spectacular widescreen LCD for unparalleled game play, it also sports wireless connectivity and a variety of multimedia features, including video, music, and digital photography. Your wildly versatile, endlessly powerful PSP practically begs you to hack and repurpose it to your liking. To save you the trouble and show you how to make the PSP do more than you ever imagined- and more than Sony ever intended- PSP Hacks is one succinct volume of 50 of the coolest, most useful, up-to-the-minute hacks for this amazing device. You'll learn how to open your PSP's hardware and what to safely plug into it. You'll explore and put to good use every hidden feature of the device. You'll be able to move all sorts of multimedia onto your PSP and find ways to extend its wireless capabilities. And you'll find out how to get the very best experience out of online game play. With PSP Hacks , you can accomplish a whole lot more than good gaming on the PSP. You'll quickly learn to surf the Web with a PSP, chat in IRC, and use the PSP to read web comics, ebooks, and RSS feeds. Other expert tips and tools allow you to sync an address book to your PSP, watch UMD movies, fool iTunes into thinking the PSP is an iPod Shuffle, and much more. The innovative hacks, tweaks, and how-tos in this essential guide make it easy to customize your PSP, take full advantage of features, capabilities, and functionality far beyond what's listed in the PSP user manual, and make your PSP perform countless tricks that only an all-in-one portable entertainment unit as remarkable and revolutionary as this one could.
Internet Core Protocols: The Definitive Guide provides the nitty-gritty details of TCP, IP, and UDP. Many network problems can only be debugged by working at the lowest levels--looking at all the bits traveling back and forth on the wire. This guide explains what those bits are and how to interpret them. It's the only book on Internet protocols written with system and network administrators in mind.
SEO--short for Search Engine Optimization--is the art, craft, and science of driving web traffic to websites. Web traffic is food, drink, and oxygen--in short, life itself--to any web-based business. Whether your website depends on broad, general traffic, or high-quality, targeted traffic, this PDF has the tools and information you need to draw more traffic to your site. You'll learn how to effectively use PageRank (and Google itself); how to get listed, get links, and get syndicated; and much more. The field of SEO is expanding into all the possible ways of promoting web traffic. This breadth requires a range of understanding. In this PDF you'll find topics that cover that range, so you can use SEO to your benefit. Those topics include: Understanding how to best organize your web pages and websites. Understanding technologic and business tools available that you can use to achieve your SEO goals. Understanding how Google works. (Since Google is far and away the most important search engine, effectively using SEO means effectively using Google. This PDF covers how to boost placement in Google search results, how not to offend Google, how best to use paid Google programs, and more.) Understanding best SEO practices (whether your organization is small and entrepreneurial, or whether you have responsibility for a large web presence). When you approach SEO, you must take some time to understand the characteristics of the traffic that you need to drive your business. Then go out and use the techniques explained in this PDF to grab some traffic--and bring life to your business.
Effective awk Programming,3rd Edition, focuses entirely on awk, exploring it in the greatest depth of the three awk titles we carry. It's an excellent companion piece to the more broadly focused second edition. This book provides complete coverage of the gawk 3.1 language as well as the most up-to-date coverage of the POSIX standard for awk available anywhere. Author Arnold Robbins clearly distinguishes standard awk features from GNU awk (gawk)-specific features, shines light into many of the "dark corners" of the language (areas to watch out for when programming), and devotes two full chapters to example programs. A brand new chapter is devoted to TCP/IP networking with gawk. He includes a summary of how the awk language evolved. The book also covers: Internationalization of gawk Interfacing to i18n at the awk level Two-way pipes TCP/IP networking via the two-way pipe interface The new PROCINFO array, which provides information about running gawk Profiling and pretty-printing awk programs In addition to covering the awk language, this book serves as the official "User's Guide" for the GNU implementation of awk (gawk), describing in an integrated fashion the extensions available to the System V Release 4 version of awk that are also available in gawk. As the official gawk User's Guide, this book will also be available electronically, and can be freely copied and distributed under the terms of the Free Software Foundation's Free Documentation License (FDL). A portion of the proceeds from sales of this book will go to the Free Software Foundation to support further development of free and open source software. The third edition of Effective awk Programming is a GNU Manual and is published by O'Reilly & Associates under the Free Software Foundation's Free Documentation License (FDL). A portion of the proceeds from the sale of this book is donated to the Free Software Foundation to further development of GNU software. This book is also available in electronic form; you have the freedom to modify this GNU Manual, like GNU software. Copies published by the Free Software Foundation raise funds for GNU development.
Ready to stand up and create positive change at work, but reluctant to speak up? True leadership doesn't always come from a position of power or authority. By teaching you skills and providing practical advice, this handbook shows you how to engage your coworkers and bosses and bring your ideas forward so that they are heard, considered, and acted upon.Authors Carmen Medina and Lois Kelly--once rebels themselves--reveal ways to navigate your workplace, avoid common mistakes and traps, and overcome the fears that may be holding you back. You can achieve more success and less frustration, help your organization do better work, and--most important--find more meaning and joy in what you do.
Like every other application in Microsoft Office suite, PowerPoint is loaded with features. So many, in fact, that even veterans don't know where to find them all. Microsoft solved this problem in PowerPoint 2007 by redesigning the user interface with a tabbed toolbar that makes features easy to locate and use. PowerPoint 2007 also boasts improved graphics, additional templates, the ability to save custom layouts, and improved collaboration through SharePoint. One thing Microsoft hasn't improved is its poor documentation. To learn the ins and outs of all the features in PowerPoint 2007, Microsoft merely offers online help. If you're familiar with previous versions of the program, you may be lost the first time you fire up the new PowerPoint; or you would be if it weren't for PowerPoint 2007: The Missing Manual . This new book, written specifically for this version of the software, not only offers the basics of how to create, save, set up, run, and print a basic bullets-and-background slideshow, but takes you into the world of multimedia, animation, and interactivity. You'll learn how to add pictures, sound, video, animated effects, and controls (buttons and links) to their slides, along with ways to pull text, spreadsheets, and animations created in other programs. You can also create your own reusable design templates and learn to automate repetitive tasks with macros. Learn how to take advantage of advanced functions (such as adding custom background images) that existed in previous PowerPoint versions, but were so cleverly hidden that few people ever found them.
Java Distributed Computing offers a general introduction to distributed computing, meaning programs that run on two or more systems. It focuses primarily on how to structure and write distributed applications and discusses issues like designing protocols, security, working with databases, and dealing with low bandwidth situations.
A SEASON OF MAGIC As the bard of the MacGregor clan, Finlay Grant is a natural-born charmer. He can easily win the heart of any lass . . . but somehow, the right words to express his love for stunning Leslie Harrison have eluded him. Yet as Christmastide approaches, Finn knows he must find a way to propose to the raven-haired beauty who has stolen his heart. A BATTLE FOR TRUE LOVE A furious Leslie Harrison could run her brothers through for promising her to another. But she will do anything to save her family from dishonor . . . even though in her heart she knows no other man but Finn will do. When Leslie's betrothed makes a dastardly deal, putting her family and the MacGregor clan in danger, Finn will prove that he's just as fierce in battle as he is sweet in song. Can these two lovers find a Christmas miracle that will grant them a happily-ever-after? (20000 words)
THE POUND A DAY DIET is an accelerated program designed to help dieters lose up to five pounds every five days-- without frustrating plateaus-- while enjoying all their favorite foods. It rewrites every carb/fat/calorie rule in the book! This delicious, easy-to-use, plan is specifically formulated as a Mediterranean-style diet that is carb and calorie corrected to turbocharge metabolism and weight loss. Complete with menus for 28 days (four five-day plans and four weekend plans), dieters first follow the five-day plan, switch over to the weekend plan, return to the five-day plan for the second week, and continue with the weekend plan-alternating like this right down to their goal weight. To help readers, Rocco has created 50 all-new lightning-quick 5 ingredient recipes, as well as ready-made suggestions for those who simply cannot find the time to cook; a primer on healthy and fast cooking techniques; calorie-calibrated menus and shopping lists; and a lifestyle plan for maintaining a lean, healthy body for life.
The designer, stylist, executive producer and star of Bravo's "The Rachel Zoe Project," and New York Times bestselling author is back with a new book for her fans.An unparalleled fixture in the fashion world, Rachel Zoe is distinguished and renowned for her effortless take on glamour. Her illustrious career has flourished as she has continually proven herself to be an integral part in shaping the image of Hollywood's A-list. Rachel's ever-growing audience loves to watch her every move so they can incorporate just a little bit of her unique sophistication into their own lives. Now, Rachel tells readers exactly how to do just that. From beauty and home design to traditions, entertaining, travel, and, of course, fashion, Rachel gives readers insight on every aspect of lifestyle. As she looks to her own past and where she has drawn inspiration over the course of her career-and her life-readers will learn how to feel amazing, too. Filled with never-before-seen photos from Rachel's personal collection and tips from colleagues, celebrities, family members, and more, this book is like none other.
To atone for the sins he committed serving his country, ex-covert government agent Paul Janson is determined to save the world: one person, one mission, one redemption at a time.THE JANSON OPTIONPaul Janson-a former Consular Ops legend known as "The Machine" for his deadly speed and accuracy-has a new mission. Sickened by the "sanctioned serial killings" ordered by the state department, Janson has left covert operations and is now a private security consultant. In partnership with deadly sharpshooter Jessica Kincaid, he only takes assignments that he believes will lead to the greater good. When American Synergy Corporation oil executive Kingsman Helms begs Janson to rescue his wife, Allegra, from Somali pirates, Janson and Kincaid view it as the perfect opportunity to infiltrate ASC and disrupt the company's scheme to subvert independent oil-rich African countries into wholly-owned ASC subsidiaries.Once on the ground, Janson and Kincaid discover that the pirates may be the least lethal threat in the violent chaos of anarchic Somalia. Is Allegra's kidnapping for real, or is she merely a pawn in her husband's machinations for control of the country? Janson and Kincaid quickly find themselves embroiled in a bewildering storm of plots and counterplots, and their fight to survive threatens to disrupt the entire region, and beyond...
TEMPTATION KNOWS NO BOUNDS . . . Undercover agent Sam Hawkins has devoted his life to protecting king and country. So when he receives orders to assassinate a ruthless traitor, he doesn't question his mission. But Sam didn't know his deed had a witness--the beautiful and mysterious betrayer's wife. Now he has no choice but to take her as his prisoner--one he can neither trust . . . nor resist.Élise, Lady Dunthorpe, will do anything to escape her powerful captor--including seducing him senseless. She didn't know of her miserable husband's crimes, but she has secrets of her own, secrets that threaten everything she holds dear. With his piercing dark eyes and gentle touch, Sam inflames Élise's deepest desires, but how could she ever trust a man who won't let her go? Caught between the crown he's sworn to serve and the woman he's come to love, Sam will risk his heart--and his very life--to keep her safe.(95,000 words)
New York Times bestselling author Jaime Rush brings us the third book in her paranormal series about dragons, angels, and dark magic. Kye knows that her boyfriend Kasabian is in grave danger, investigating a series of kidnapped children. She knows he's pushing her away for her own safety, but she won't let him face it alone. Kasabian will risk anything to rescue the children, and he has a bold plan to allow himself to be taken hostage by the kidnapper, Silva. While he tries to reason with Silva, Kye is racing again time to discover where the kidnapper is holding him . If Kye is reunited with Kasabian, will their combined powers be enough? The fate of the Crescents-and Kye and Kasabian's hearts-hang in the balance.