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On New Earth, a world based on a video role-playing game, fourteen-year-old Erik persuades his friends to aid him in some unusual gambits in order to save Erik's father from exile and safeguard the futures of each of their families.
The 'Sundara Kanda'--the seed-book or bija-kanda as it has been called, of the Ramayana of Valmiki--is here presented as an autonomous epic by itself, arranged under Seven Books. The verse form used is a 4-line unit in lieu of the Sanskrit anushtup sloka. I have attempted, however, neither a word-for-word translation, nor always a sloka-stanza correspondence. The span of thought often overflows the quatrain mould, thereby softening the metrical monotony.
Will Elise's love life be an epic win or an epic fail? At Coral Tree Prep in Los Angeles, who your parents are can make or break you. Case in point: As the son of Hollywood royalty, Derek Edwards is pretty much prince of the school-not that he deigns to acknowledge many of his loyal subjects. As the daughter of the new principal, Elise Benton isn't exactly on everyone's must-sit-next-to-at-lunch list. When Elise's beautiful sister catches the eye of the prince's best friend, Elise gets to spend a lot of time with Derek, making her the envy of every girl on campus. Except she refuses to fall for any of his rare smiles and instead warms up to his enemy, the surprisingly charming social outcast Webster Grant. But in this hilarious tale of fitting in and flirting, not all snubs are undeserved, not all celebrity brats are bratty, and pride and prejudice can get in the way of true love for only so long.
First memory. First kiss. First love. First fight. First heartbreak. There's a first time for everything. Discover five first-time authors with sneak peeks of their debut novels-Don't Turn Around by Michelle Gagnon, Breathe by Sarah Crossan, What's Left of Me by Kat Zhang, Through to You by Emily Hainsworth, and Defiance by C. J. Redwine.
Cassandra Pybus adds greatly to the work of [previous] scholars by insisting that slaves stand at the center of their own history . . . Her 'biographies' of flight expose the dangers that escape entailed and the courage it took to risk all for freedom. Only by measuring those dangers can the exhilaration of success be comprehended and the unspeakable misery of failure be appreciated.--Ira Berlin, from the ForewordDuring the American Revolution, thousands of slaves fled their masters to find freedom with the British. Epic Journeys of Freedom is the astounding story of these runaways and the lives they made on four continents. Having emancipated themselves, with the rhetoric about the inalienable rights of free men ringing in their ears, these men and women struggled tenaciously to make liberty a reality in their own lives.This alternative narrative of freedom fought for and won is uniquely compelling; historian Cassandra Pybus's groundbreaking research has uncovered individual stories of runaways who left America to forge difficult new lives in far-flung corners of the British Empire. Harry, for example, one of George Washington's slaves, escaped from Mount Vernon in 1776, was evacuated to Nova Scotia in 1783, and eventually relocated to Sierra Leone in West Africa with his wife and three children. Ralph Henry, who ran away from the Virginia firebrand Patrick Henry in 1776, took a similar path to precarious freedom in Sierra Leone, while others, such as John Moseley and John Randall, were evacuated with the British forces to England. Stranded in England without skills or patronage during a period of high unemployment, they were among thousands of newly freed poor blacks who struggled just to survive. While some were relocated to Sierra Leone, others, like Moseley and Randall, found themselves transported to the distant penal colony of Botany Bay, in Australia. Epic Journeys of Freedom, written in the best tradition of history from the bottom up, is a fascinating insight into the meaning of liberty; it will change forever the way we think about the American Revolution.From the Hardcover edition.
This is the first book to focus on Latin epic verse saints' lives in their medieval historical contexts. Anna Taylor examines how these works promoted bonds of friendship and expressed rivalries among writers, monasteries, saints, earthly patrons, teachers and students in Western Europe in the central Middle Ages. Using philological, codicological and microhistorical approaches, Professor Taylor reveals new insights that will reshape our understanding of monasticism, patronage and education. These texts give historians an unprecedented glimpse inside the early medieval classroom, provide a nuanced view of the complicated synthesis of the Christian and Classical heritages, and show the cultural importance and varied functions of poetic composition in the ninth, tenth and eleventh centuries.
A great king Enkidu is created by the gods to challenge the arrogant King Gilgamesh. But both become friends to slay the evil monster Humbaba. When Enkidu is killed, his death haunts and breaks the mighty Gilgamesh who resolves to find the secret of eternal life.
In swift, witty chapters that flawlessly capture the pace and character of New York City, acclaimed diarist Edward Robb Ellis presents his masterpiece: a thorough, and thoroughly readable, history of America's largest metropolis. Ellis narrates some of the most significant events of the past three hundred years and more-the Revolutionary and Civil Wars, Alexander Hamilton and Aaron Burr's fatal duel, the formation of the League of Nations, the Great Depression-from the perspective of the city that experienced, and influenced, them all. Throughout, he infuses his account with the strange and delightful anecdotes that a less charming tour guide might omit, from the story of the city's first, block-long subway to that of the blizzard of 1888 that turned Macy's into one big slumber party. Playful yet authoritative, comprehensive yet intimate, The Epic of New York City confirms the words of its own epigraph, spoken by Oswald Spengler: "World history is city history," particularly when that city is the Big Apple.
When Neil Armstrong and Buzz Aldrin walked on the moon in 1969, they personified an almost unimaginable feat-the incredibly complex task of sending humans safely to another celestial body. This extraordinary odyssey, which grew from the rivalry between the United States and the Soviet Union during the Cold War, was galvanized by the Sputnik launch in 1957. To mark the fiftieth anniversary of Sputnik, National Geographic recaptures this gripping moment in the human experience with a lively and compelling new account. Written by Smithsonian curator Von Hardesty and researcher Gene Eisman, Epic Rivalry tells the story from both the American and the Russian points of view, and shows how each space-faring nation played a vital role in stimulating the work of the other. Scores of rare, unpublished, and powerful photographs recall the urgency and technical creativity of both nations' efforts. The authors recreate in vivid detail the "parallel universes" of the two space exploration programs, with visionaries Wernher von Braun and Sergei Korolev and political leaders John F. Kennedy and Nikita Khrushchev at the epicenters. The conflict between countries, and the tense drama of their independent progress, unfolds in vivid prose. Approaching its subject from a uniquely balanced perspective, this important new narrative chronicles the epic race to the moon and back as it has never been told before-and captures the interest of casual browsers and science, space, and history enthusiasts alike.
The Epicenter of Crisis argues that six contiguous states epitomize the security challenges of a post-9/11, globalized world: Saudi Arabia, Syria, Iraq, Iran, Afghanistan, and Pakistan.
For ten years, Hugo Whittier, upper-class scion, former gigolo, failed belle-lettrist has been living a hermit's existence at Waverly, his family's crumbling mansion overlooking the Hudson. He passes the time reading Montaigne and M. F. K. Fisher, cooking himself delicious meals, smoking an endless number of cigarettes, and nursing a grudge against the world. But his older brother, Dennis, has returned, in retreat from an unhappy marriage, and so has his estranged wife, Sonia, and their (she claims) daughter, Bellatrix, shattering Hugo's cherished solitude. He's also been told by a doctor that he has the rare Buerger's disease, which means that unless he stops smoking he will die--all the more reason for Hugo to light up, because his quarrel with life is bitter and an early death is a most attractive prospect. As Hugo smokes and cooks and sexually schemes and pokes his perverse nose into other people's marriages and business, he records these events as well as his mordant, funny, gorgeously articulated personal history and his thoughts on life and mortality in a series of notebooks. His is one of the most perversely compelling literary personalities to inhabit a novel since John Lanchester'sThe Debt to Pleasure, and his ancestors include the divinely cracked and eloquent narrators of the works of Nabokov. As snobbish and dislikable as Hugo is, his worldview is so enticingly conveyed that even the most resistant reader will be put under his spell. His insinuating voice gets into your head and under your skin in the most seductive way. And as he prepares what may be his final Christmas feast for family and friends, readers will have to ask, "Is this the end of Hugo?" The Epicure's Lamentis a wry and witty novel about love and death and family, a major contribution to a vein of literature that the author Kate Christensen has dubbed "loser lit. " It more than fulfills the bright promise of her lavishly praised previous two novels, and gives us an antihero for our time--hard to like, impossible to resist.
For Epicurious's enormous and devoted community -- 7.5 million unique visitors a month -- and home cooks seeking a perfectly curated roster of diverse recipes, here are the top-rated recipes from Epi, compiled conveniently in a book with brand-new stunning colour photography. Epicurious.com is, undisputedly, the website for people who like to cook. Launched in the dark ages of 1995, Epi was one of the first on the block and is the go-to respected food site among home cooks. Now, The Epicurious Cookbook provides a completely new experience for Epi's fans with a perfectly curated roster of Epi's 300 best recipes organized seasonally for breakfasts, starters, mains, sides, breads, and desserts. The book includes new headnotes and 100 new photographs, plus dozens of member recipes that have been tested in Epi's kitchens. Throughout, readers will find clever substitutions, special holiday menus, and make-ahead tips, from Epi's editors and community alike.
Epicureanism after the generation of its founders has been characterised as dogmatic, uncreative and static. But this volume brings together work from leading classicists and philosophers that demonstrates the persistent interplay in the school between historical and contemporary influences from outside the school and a commitment to the founders' authority. The interplay begins with Epicurus himself, who made arresting claims of intellectual independence, yet also admitted to taking over important ideas from predecessors, and displayed more receptivity than is usually thought to those of his contemporaries. The same principles of autonomy and openness figure importantly in the three major areas of focus in these essays: theology, politics and the emotions.
From an esteemed child psychiatrist: a bold, fresh, and controversial look at the faddish child-rearing practices that have created a nation of children who are depressed, alienated, often amoral, and all too often violent. The shock of the Columbine shootings and other school violence has generated a national debate, and there's a dawning realization that something incomprehensible is happening: our privileged, pampered children are turning into monsters at an alarming rate. With years of study and first-hand experience, Dr. Robert Shaw exposes the roots of what he calls The Epidemic: the violence and the more subtle behaviour problems that are jeopardizing a generation. In this eye-opening book, Dr. Shaw explains that the "advanced" parenting methods experts have promoted for the last thirty years have helped to create a nation of children who are detached loners, unable to form meaningful relationships. From infancy through the teen years, Dr. Shaw provides a map back to sanity that tracks specific misguided parenting techniques and shows parents how to get and keep their children on track and create the environment necessary for a healthy psychological future. Some of the important ground Dr. Shaw covers includes: The myths and realities of bonding and attachment How to recognize when day care is working - and when it isn't Landmarks to look for in your children's moral and ethical development Self-centeredness versus self-esteem Keeping the media from mugging your child What can be done with a child who is out of control Dr. Shaw challenges us to confront a very real problem, then helps us take steps forward using common sense and humanity. The Epidemic calls us to become better parents--and feel better about the choices we make for our children.
A call for parents to take responsibility for their children and give them what they truly need in order to grow, thrive, and love. Take a good look around you: you can't go into stores or restaurants without seeing joyless children screaming and sulking while their parents ignore them. According to esteemed child psychiatrist Robert Shaw, this epidemic has become so much the norm that we often don't recognize its warning signs. This bold and timely book tells you how to save your child and your family--with a commonsense approach that cuts to the core of the problem and shows us the cure. The Epidemic covers: Developing your child's ability to love Managing child care and minimizing the damage Raising cooperative, joyful, and creative children Promoting self-esteem and confidence rather than self-centeredness Avoiding the harmful effects of electronic media Healing angry, contemptuous, withdrawn, and out-of-control children
A brilliant, cutting-edge exploration of the dramatic rise of allergic and autoimmune diseases and the controversial, potentially groundbreaking therapies that scientists are developing to correct these disorders Whether it is asthma, food or pollen allergies, type-1 diabetes, lupus, multiple sclerosis, or Crohn's disease, everyone knows someone who suffers from an allergic or autoimmune disorder. And if it appears that the prevalence of these maladies has increased recently, that's because it has--to levels never before seen in human history. These days no fewer than one in five--and likely more--Americans suffers from one of these ailments. We seem newly, and bafflingly, vulnerable to immune system malfunction. Why? Science writer Moises Velasquez-Manoff explains the latest thinking about this problem and explores the remarkable new treatments in the works. In the past 150 years, improved sanitation, water treatment, and the advent of vaccines and antibiotics have saved countless lives, nearly eradicating diseases that had plagued humanity for millennia. But now, a growing body of evidence suggests that the very steps we took to combat infections also eliminated organisms that kept our bodies in balance. The idea that we have systematically cleaned ourselves to illness challenges deeply entrenched notions about the value of societal hygiene and the harmful nature of microbes. Yet scientists investigating the rampant immune dysfunction in the developed world have inevitably arrived at this conclusion. To address this global "epidemic of absence," they must restore the human ecosystem. This groundbreaking book explores the promising but controversial "worm therapy"--deliberate infection with parasitic worms--in development to treat autoimmune disease. It explains why farmers' children so rarely get hay fever, why allergy is less prevalent in former Eastern Bloc countries, and how one cancer-causing bacterium may be good for us. It probes the link between autism and a dysfunctional immune system. It investigates the newly apparent fetal origins of allergic disease--that a mother's inflammatory response imprints on her unborn child, tipping the scales toward allergy. In the future, preventive treatment--something as simple as a probiotic--will necessarily begin before birth. An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results. An Epidemic of Absence considers the critical immune stimuli we inadvertently lost as we modernized, and the modern ills we may be able to correct by restoring them. At stake is nothing less than our health, and that of our loved ones. Researchers, meanwhile, have the good fortune of living through a paradigm shift, one of those occasional moments in the progress of science when a radically new way of thinking emerges, shakes things up, and suggests new avenues of treatment. You'll discover that you're not you at all, but a bustling collection of organisms, an ecosystem whose preservation and integrity require the utmost attention and care.
Recognizing a crisis in American health care, but rejecting any solutions that are not "market-based," Halvorson (chair and CEO, Kaiser Permanente) and Isham (chief health officer, HealthPartners) explore some of the reasons for rising health care costs (absolving the HMOs for any responsibility) and make suggestions for improving the situation. Their proposed system rests largely on promoting evidence- based care for physicians and transferring greater costs to patients to improve "efficiency."
This book is meant for adoption in first courses on epidemiology in Medical Schools and Faculties of Public Health in developing and transition countries and in workshops in these countries, taught for example by members of international organizations. It is also suitable for parallel or second reading within curricula in developed countries and for teaching epidemiology in a Master's programme on "International Health". The book will enable any lecturer to compose his or her introductory courses on epidemiology by selecting the material deemed appropriate. It will provide a solid foundation for more advanced teaching. The intended readership consists in the first place of general medical students; students following the programme "Preventive Physician" that runs parallel to general medical studies in some countries; students starting to specialize in Public Health; and lecturers in epidemiology. The book can also serve well as an introduction into epidemiology for anybody else interested in this field, for example staff of health institutions. Examples and practical work are taken from the present situation of health in Vietnam, which can easily be adapted to any other developing or transition country.
Concise, fast-paced, intensive introduction to clinical research design for students and clinical research professionals Readers will gain sufficient knowledge to pass the United States Medical Licensing Examination part I section in Epidemiology
This completely revised and updated edition of an outstanding text addresses the fundamental knowledge of epidemiological methods and statistics that can be applied to evolving systems, programs, technologies, and policies. This edition presents new chapters on causal thinking, ethics, and web resources, analyzes data on multinational increases in poverty and longevity, details the control of transmissible diseases, and explains quality management, and the evaluation of healthcare system performance.
A comprehensive collection of optimized methods for dissecting the mechanisms that control epidermal growth factors (EGF) and their regulators in both normal and pathological states. These readily reproducible techniques range from the study of purified EGF receptor to complex signaling and processing networks in intact cells, including a chapter on the clinical and pharmacological considerations of their use in cancer therapy. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer's disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Prescriber's Guide to Antiepileptic Drugs provides a practical and concise reference guide for use by all those clinicians and allied health professionals that treat or care for patients with epilepsy. In full colour throughout, this volume presents the antiepileptic drugs (AEDs) in alphabetical order and for each AED the information is divided into eight coloured sections: general therapeutics, pharmacokinetics, interaction profile, adverse effects, dosing and use, special populations, and suggested reading. This handy pocket guide will be an excellent companion for all clinicians that treat patients with epilepsy.
Epilepsy: The Ultimate Teen Guide dispels the myths, misconceptions, and misunderstandings about epilepsy and the people who have the disorder. It provides factual medical information and advice for teens on how to live a normal life. Stories from teens who have epilepsy show readers they can participate in normal activities. They also offer advice on whether and how to tell friends, dates, teachers, or an employer about the condition. This book concludes with an extensive list of publications, websites, and organizations, as well as an appendix that covers the Americans with Disabilities Act and how it applies to people who have epilepsy.
The most acclaimed European graphic novel of the last ten years, Epileptic is David B.'s story of his brother's battle with epilepsy, but it turns into a penetrating and sometimes lacerating self-examination on the author's part, as he delves into his own complex emotions and his family's troubled history, as well as his own youthful fantasy life. Particularly pointed is his description of the family journey from one attempted cure to another, including acupuncture, spiritualism and macrobiotics. David B.'s drawing is utterly extraordinary, balancing literal representation and expressionist psychological distortion.
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