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Thirty years ago, ecstasy and torment took hold of John Rivers, shocking him out of ?half-baked imbecility into something more nearly resembling the human form. ' He had an affair with the wife of his mentor, Henry Maartens--a pathbreaking physicist, winner of the Nobel Prize, and a figure of blinding brilliance--bringing the couple to ruin. Now, on Christmas Eve while a small grandson sleeps upstairs, John Rivers is moved to set the record straight about the great man and the radiant, elemental creature he married, who viewed the renowned genius through undazzled eyes.
In 1980 an eccentric American millionaire launched a 'Nobel Prize sperm bank', intended to create a new generation of superkids. Stocked with the seed of gifted scientists, inventors, businessmen and thinkers, including several Nobel laureates, the 'genius factory' produced more than 200 children before it quietly closed its doors in 1999. What happened to them? Were they the brilliant progeny its founder expected? In this stunning, eye-opening and hugely entertaining book, David Plotz tracks down many...
This is the spectacular rags-to-riches story of James Morrison (1789-1857), who began life humbly but through hard work and entrepreneurial brilliance acquired a fortune unequalled in nineteenth-century England. Using the extensive Morrison archive, Caroline Dakers presents the first substantial biography of the richest commoner in England, recounting the details of Morrison's personal life while also placing him in the Victorian age of enterprise that made his success possible.An affectionate husband and father of ten, Morrison made his first fortune in textiles, then a second in international finance. He invested in North American railways, was involved in global trade from Canton to Valparaiso, created hundreds of jobs, and relished the challenges of "the science of business". His success enabled him to acquire land, houses, and works of art on a scale to rival the grandest of aristocrats.
Jack's difficulties in dealing with his younger sister Annie, a child genius, worsen when Annie claims to have a new friend from the twenty-fifth century and Jack worries that this development will keep him from going to visit his father in America.
The Genius is the gripping account of Bill Walsh's career and how, through tactical and organizational skill, he transformed the San Francisco Forty Niners from a fallen franchise into a football dynasty. Along with his right-hand man John McVay, Walsh built the foundation for this success by drafting or trading for a durable core of stars, including Joe Montana, Fred Dean, and Hacksaw Reynolds. (Walsh would later restock the team with such players as Jerry Rice, Steve Young, and Charles Haley.) The key to Walsh's genius perhaps lay in his keen understanding of his athletes' psyches-- he knew what brought out the best in each of them. With unmatched access to players, fellow coaches, executives, beat reporters, and Walsh himself, David Harris recounts the whole story--including Walsh's pre-Niners odyssey, the demons that pushed him throughout his career, and the scope of his impact on the game beyond the field and locker room. In the end, Harris reveals the brilliant man behind the coaching legend.
This hugely entertaining biography of the founding editor of The New Yorker tells the diverting story of how Ross and the brilliant group of people he gathered around him--including James Thurber, Charles Addams, Dorothy Parker, and John O'Hara--devised the formula that made the magazine such a popular and critical success. Photos & cartoons.
This biography presents the shy, witty, eccentric physicist Szilard, co-designer of the first nuclear reactor in 1942, who worked first to prevent, then to hasten, and finally to outlaw nuclear weapons. Annotation c. by Book News, Inc., Portland, OR.
A profound and eloquent reading of the first chapter of the Bible.
Wendy Lesser--a celebrated essayist in her own right--has put together a rich and often surprising work, a book brimming with pleasures for lovers of literature, travel, memoir, and, above all, language.
This fascinating book by one of Britain's most acclaimed young Shakespeare scholars explores the extraordinary staying-power of Shakespeare's work. Bate opens by taking up questions of authorship, asking, for example, Who was Shakespeare, based on the little documentary evidence we have? Which works really are attributable to him? And how extensive was the influence of Christopher Marlowe? Bate goes on to trace Shakespeare's canonization and near-deification, examining not only the uniqueness of his status among English-speaking readers but also his effect on literate cultures across the globe. Ambitious, wide-ranging, and historically rich, this book shapes a provocative inquiry into the nature of genius as it ponders the legacy of a talent unequaled in English letters. A bold and meticulous work of scholarship, The Genius of Shakespeare is also lively and accessibly written and will appeal to any reader who has marveled at the Bard and the enduring power of his work.
Now that the Axis Institute for World Domination has been blown up; the founder, Dr. Phineas Darkkon, has died; and Prosper English (who enrolled Cadel in the first place) is in jail for myriad offenses, Cadel Piggott has round-the-clock surveillance so he'll be safe until he testifies against Prosper English. But nobody seems to want Cadel. Not Fiona, his social worker; not Saul Greeniaus, the detective assigned to protect him. When he is approached by the head of Genius Squad--a group formed to investigate GenoME, one of Darkkon's pet projects--Cadel is dubious Genius Squad can offer him a real home and all the technology his heart desires. But why can't he bring himself to tell Saul what the group is really up to? And how can Genius Squad protect Cadel once Prosper English breaks out of jail?
From the back of the book: School for crime A daring million-dollar bank robbery leads Frank and Joe to Chartwell Academy. Certain that the high-tech thief is someone at the exclusive prep school, Frank enrolls as a student, and Joe gets a job as a janitor. But going undercover on the secluded campus proves extremely dangerous. From battling a raging dorm fire, to being hunted through a graveyard by a masked gunman -the brother detectives find they're up against a brainy enemy who's intent on making a twin killing. =========== From inside the book: HIS BROTHER'S GRAVE Joe was shoveling furiously, throwing mounds of dirt around Frank. Within ten minutes Frank was practically covered. "Joe! Think of what you're doing!" Frank yelled. But Joe was now foaming at the mouth. His eyes were rolling in their sockets, and he was babbling nonsense words. Just as Frank was about to be covered, Joe began to shriek insanely. He backed away from the grave as if he were being attacked. "Finish your job!" the masked man demanded. But Joe was too far gone. The masked man aimed his gun at Joe. "I was hoping not to do this, my friend, but you've failed me." Bracing the gun with two outstretched arms, he fired. . . .
Boy-genius Cadel Piggot has a new name (Cadel Greenaius), a new family, and a new life. No more illegal hacking, no more false identities, and most of all, no more Prosper English. But when his best friend Sonja is attacked, it's up to him to figure out who was behind it. Before he knows it, Cadel is crossing oceans and continents, barrelling back into the depths of the criminal activity he thought he'd left behind, and coming face to face with Prosper English once again. Can Cadel track down Prosper before it's too late? And what rules will he have to break in the process?
Controversial, confrontational, and driven, Coach Geno Auriemma is a force to be reckoned with - and the most accomplished male coach in women's basketball today. In his relentless quest for excellence at the University of Connecticut, he has led the Huskies to five national championships. Yet his soul never rests. For Auriemma, life affords only the briefest moments of happiness - a good round of golf, forty minutes of great basketball, a day at the beach with his family, a nice glass of wine - while disaster is seemingly always waiting to strike. It's a fatalistic philosophy, a remnant of his hardscrabble early years, but it's an outlook that has driven him to unparalleled success." In this deeply personal memoir, Geno Auriemma reveals for the first time the man behind the legend. He talks candidly about his coaching style - famed for being one of the most demanding in all the sports world. He spills the beans about his stormy dealings with other coaches such as his archrival, Pat Summitt of the University of Tennessee. And with warmth and a genuine love for his champions, he writes openly about Diana Taurasi, Sue Bird, Nykesha Sales, Rebecca Lobo, Swin Cash, and all of his other UConn stars who have gone on to stellar WNBA careers. You get a courtside seat to all of the action - including an epilogue on the 2004-05 season, as well as interviews with the team's most celebrated players.
The 1904 war that broke out in present day Namibia after the Herero tribe rose against an oppressive colonial regime--and the German army's brutal suppression of that uprising--are the focus of this collection of essays. Exploring the annihilation of both the Herero and Nama people, this selection from prominent researchers of German imperialism considers many aspects of the war and shows how racism, concentration camps, and genocide in the German colony foreshadow Hitler's Third Reich war crimes.
In this harrowing novel, the world's cities have been reduced to cinder and ash and alien plants have overtaken the earth. The plants, able to grow the size of maples in only a month and eventually reach six hundred feet, have commandeered the world's soil and are sucking even the Great Lakes dry. In northern Minnesota, Anderson, an aging farmer armed with a Bible in one hand and a gun in the other, desperately leads the reduced citizenry of a small town in a daily struggle for meager existence. Throw into this fray Jeremiah Orville, a marauding outsider bent on a bizarre and private revenge, and the fight to live becomes a daunting task.
The human genome, the complete set of genes housed in twenty-three pairs of chromosomes, is nothing less than an autobiography of our species.
Genome: The Story of the Most Astonishing Scientific Adventure of Our Time - The Attempt to Map All the Genes in the Human Bodyby Jerry E. Bishop Michael Waldholz
By far the best popular work written about the impact of molecular biology on science. An incisive, thoughtful and thorough work that educates and entertains.
Biologist Craig Venter founded the company Celera in an effort to decode the human genome before the U. S. government's Human Genome Project, expecting to get very rich in the process. This book chronicles the company's work in the 1990s, looking at the economic, political, scientific, and institutional rivalries and competitions that eventually led to the company's eventual implosion. Annotation ©2004 Book News, Inc. , Portland, OR (booknews. com)
"Genomes and What to Make of Them" opens with a brief history of the science of genetics and genomics, from Mendel to Watson and Crick and all the way up to Craig Venter. From there the authors delve into the use of genomics in determining evolutionary paths -- and what it can tell us, for example, about how far we really have come from our ape ancestors. Barnes and Dupré then consider both the power and risks of genetics, from the economic potential of plant genomes to overblown claims that certain human genes can be directly tied to such traits as intelligence or homosexuality. Ultimately, the authors argue, we are now living with a new knowledge as powerful in its way as nuclear physics, and the stark choices that face us -- between biological warfare and gene therapy, a new eugenics or a new agricultural revolution -- will demand the full engagement of both scientists and citizens.
The completion of a consensus draft sequence for the human genome was the starting point for more thorough investigations of individual genome variation. The development of array-based strategies made it possible to look at our genome in new ways and for new types of variation to be discovered and characterized. Characterization of copy number variation and other forms of structural genetic variation has highlighted the complexity of human genetic variation and also provided significant insight into the evolution and dynamic nature of our genome. Genomic Structural Variants: Methods and Protocols provides an in-depth description of the developments in our understanding of structural genetic variation and its implications for human disease, from the introduction of microarrays up to current state-of-the-art sequencing strategies. It covers the major technologies used for research and diagnostics as well as web-based resources for variation data, and it then goes into depth regarding specific regions of the genome that differ in variation content. Specific patient groups where copy number variation has been shown to be of great importance are highlighted, and implications for both pre-natal and standard diagnostics are described. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Genomic Structural Variants: Methods and Protocols provides complete comprehensive coverage of this burgeoning field.
With the arrival of genomics and genome sequencing projects, biology has been transformed into an incredibly data-rich science. The vast amount of information generated has made computational analysis critical and has increased demand for skilled bioinformaticians. Designed for biologists without previous programming experience, this textbook provides a hands-on introduction to Unix, Perl and other tools used in sequence bioinformatics. Relevant biological topics are used throughout the book and are combined with practical bioinformatics examples, leading students through the process from biological problem to computational solution. All of the Perl scripts, sequence and database files used in the book are available for download at the accompanying website, allowing the reader to easily follow each example using their own computer. Programming examples are kept at an introductory level, avoiding complex mathematics that students often find daunting. The book demonstrates that even simple programs can provide powerful solutions to many complex bioinformatics problems.
This book evolved from the editors strong belief that the information and new developments that were evolving from the rapidly growing field of genomics and that are happening primarily in the developed world have not happened at a parallel rate in the developing world. One would have hoped that by now the technologies and approaches would have been adapted on a far greater scale. In addition to this, the associated information is not always easily accessible, and is not disseminated in a format that can become a useful reference for scientists, students and others who reside in developing countries.
This newest volume of Advances in Neurobiology discusses the utilization of genomic and proteomic technologies, to address facets of neurobiology including development and epigenetic regulation, functions in learning and memory, and changes associated with neurological and psychiatric disorders.
Expert researchers from academia, industry, and leading genome centers provide a comprehensive generic set of protocols for gene hunting and genome analysis. Drawing on emerging technologies in the fields of bioinformatics and proteomics, these protocols cover not only those traditionally recognized as genomics, but also early therapeutic approaches exploiting the potential of gene therapy. Highlights include methods for the analysis of differential gene expression, SNP detection, comparative genomic hybridization, and the functional analysis of genes, as well as the use of bioinformatics for gene identification and the prediction of protein function.
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