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The germline is unique in mammals as it is the only cell lineage that undergoes mitosis, meiosis, and differentiation, making these cells amenable to in-depth genomic and mechanistic studies. In Germline Development: Methods and Protocols, expert researchers provide a wide-ranging collection of techniques that can be applied to the study of both the male and female germline. As the techniques used for isolating and studying male and female germ cells are slightly dissimilar, the different technologies are grouped under two sections in this volume, namely, male germline and female germline. This collection brings the field of germline developmental studies together such that readers can find, in a single volume, techniques that allow the isolation of gonads with germ cells at different stages of development, the study of the genomics and epigenomics of germ cells, and an examination of the role of single genes in the developmental potential and function of germ cells. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and the avoidance of known pitfalls. Comprehensive and cutting-edge, Germline Development: Methods and Protocols serves as a comprehensive text to individuals, particularly researchers in reproductive and developmental biology, who are interested in studying cells of the germ lineage.
In this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. The volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.
In the wake of the anthrax letters following the attacks on the World Trade Center, Americans have begun to grapple with two difficult truths: that there is no terrorist threat more horrifying -- and less understood -- than germ warfare, and that it would take very little to mount a devastating attack on American soil. In Germs, three veteran reporters draw on top sources inside and outside the U.S. government to lay bare Washington's secret strategies for combating this deadly threat. Featuring an inside look at how germ warfare has been waged throughout history and what form its future might take (and in whose hands), Germs reads like a gripping detective story told by fascinating key figures: American and Soviet medical specialists who once made germ weapons but now fight their spread, FBI agents who track Islamic radicals, the Iraqis who built Saddam Hussein's secret arsenal, spies who travel the world collecting lethal microbes, and scientists who see ominous developments on the horizon. With clear scientific explanations and harrowing insights, Germs is a masterfully written -- and timely -- work of investigative journalism.
Analysis of the role of germs and biological weaponry in future wars.
Apache warrior Geronimo led one of the last major independent Indian uprisings, and personified the struggle of Native Americans during westward expansion. Aimed at high school and undergraduate students, this biography provides an account of Geronimo's life from his traditional Apache upbringing to his final days as a celebrity prisoner of war, within the context of key historical and cultural events of his lifetime, including Native American traditions. The biography draws on primary sources such as Geronimo's autobiography and contemporary newspaper accounts, and is illustrated with b&w historical photos. A timeline and a glossary are also included. Stout is a librarian at Pima Community College in Tucson. She has published six books on Native American tribes. Annotation c2010 Book News, Inc., Portland, OR (booknews.com)
A biography of the Apache warrior who led attacks on settlers and soldiers in Mexico and the Southwestern United States during the 1870s and 1880s.
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. It's Halloween on Mouse Island, and it seemed like everyone was out to get me, Geronimo Stilton! My cousin Trap kept pulling scary pranks on me. And then my sister Thea told me I had to write a book about Halloween in less than one day! Before you could say boo, my nephew Benjamin had dragged me to a graveyard to do research. There I met a very spooky mouse who -- yikes! -- tried to lock me up in her coffin! Oh, how would a 'fraidy mouse like me ever survive the year's scariest holiday?
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. My grandfather William Shortpaws -- also known as Cheap Mouse Willy -- was back at The Rodent's Gazette, and he was determined to torture me. He wanted to publish a guide book to Ratzikistan, the Siberia of Mouse Island. And he ordered *me* to go there to write it! But as you know, dear reader, I HATE TRAVELING!
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. My sister had come up with a new way to torment me. She'd combined my two least favorite things - travel and ghosts! Thea had heard rumors of a haunted pirate treasure buried on a desert island. And before I could say "avast ye scurvy rats," she'd dragged me into her treasure hunt!
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. Ah, there's nothing like a relaxing vacation on the beach! I would spread out by the crystal-clear water with a good book. What more could a mouse want? At least, that was the plan. But somehow, my vacations never seem to go according to plan. Instead of a beautiful seaside resort, I found myself in a fleabag hotel that was falling down around my ears! Oh, would I ever be able to relax and enjoy my vacation??
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. Holey cheese, what an adventure! I was off to Niagara Falls with my nephew Benjamin's class. It was a beautiful place -- truly one of the most amazing sights I'd ever seen. But unfortunately, I was surrounded by mischievous young mouselets who were determined to send me over the Falls in a barrel! Oh, would I ever make it back to Mouse Island alive?
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. Holey cheese, what an adventure! I was off to the Ratlápagos Islands with my family in search of a long-lost buried treasure. But oh, how I hate traveling! Being on a ship in the middle of the sea wasn't my idea of a fabumouse time. And I was beginning to suspect that we weren't the only ones searching for the treasure. . . .
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. G'day, mate! I was searching for ideas for my new book, and my friend Petunia Pretty Paws knew just where to find them -- in Australia. Holey cheese, it sounded like a fabumouse adventure! But between surfing with sharks, being chased by poisonous snakes, and getting lost in the outback, I was beginning to wonder if this trip down under was really a good idea. Kangaroos and koalas and crocs -- oh, my! Would I ever see New Mouse City again?
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. Who Is Geronimo Stilton? That's me! I run a newspaper, but my true passion is writing tales of adventure. Here on Mouse Island, my books are all best-sellers! What's that? You've never read one? Well, my books are full of fun. They are whisker-licking good stories, and that's a promise! The Case of Curlypaw Cannycat's Castle I was lost in a dark, spooky forest! Until I stumbled upon Curlypaw Cannycat's Castle. The castle was completely empty, or so I thought. But I quickly discovered that it was haunted - by cats! Let me tell you, this was one case where curiosity almost killed the mouse!
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. Tuslaarai! Tuslaarai! That's Mongolian for "Help!" and holey cheese did I need some! I was lost in the Gobi Desert, looking for a hidden treasure. So far, all I had found were sandstorms, camels, and giant dinosaur bones? Rat-munching rattlesnakes - how do I get myself into these situations?
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. I, Geronimo Stilton, am not a big fan of races. I like to take my time and smell the cheese! But when my friend Bruce Hyena invited me to race across America on my bicycle, I just couldn't resist. And holey cheese, what a fabumouse adventure we had!
In each Geronimo Stilton book, another funny, cheesy adventure is always right around the corner. Each book is fast-paced, with lively full-color art and a unique format kids 7-10 will love. Geronimo has always been a 'fraidy mouse, and his super-sporty friend Bruce Hyena decides that he needs to help Geronimo learn to keep calm in extreme situations. Bruce puts Geronimo to the test through encounters with scary animals and weather in conditions ranging from the desert to the North Pole. After Bruce's crazy training, a natural weather disaster occurs on Mouse Island. Will Geronimo prove that he truly is a super mouse?
More than 18 million Geronimo Stilton books in print! Finally, I was about to leave for a relaxing vacation all by myself. I was ready to kick back and connect with nature. But somehow, my peaceful trip turned into a crazy treasure hunt in the beautiful Black Hills of South Dakota with the entire Stilton clan in tow! Our journey even included a hot-air balloon ride to Mount Rushmore. Holey cheese! This was one adventure I'd truly remember.
Each Geronimo book is fast-paced, with lively full-color art and a unique format kids 7-10 will love. When Wild Willie showed up at my door and invited me to travel with him to Japan, I jumped at the chance. We were in search of an ancient, legendary samurai scroll that holds the secret to a long-lost fighting technique. The scroll had fallen into the wrong hands, and it was up to me and Wild Willie to track it down and save the day. But first, we would have to fight a group of talented ninjas. Holey cheese -- this would be one adventure I would never forget!
Enter the world of Geronimo Stilton, where another funny adventure is always right around the corner. Each book is a fast-paced adventure with lively art and a unique format kids 7-10 will love. I have never been a brave mouse... but lately, my fears were taking over my life! Soon I was too afraid even to leave my mousehole. That's when Thea and Trap decided to cure me. They dragged me away on an airplane (I'm afraid of flying!) all the way to the jungle. There I was forced to eat bug soup, climb trees as high as skyscrapers, swim in raging rivers, and even wrangle snakes! How would a 'fraidy mouse like me ever survive?
Petunia Pretty Paws, Bugsy Wugsy, Benjamin and I were exploring underwater at Pirate Island one day, when we made an amazing discovery. It was an huge clam that had an enormouse pearl inside! I was so excited about this extremely rare, precious pearl that I wrote a special feature about it in the Rodent's Gazette. But that attracted good attention--and bad! The enormouse pearl was in danger. Would my friends and I be able to protect it?
Holey cheese! Join Geronimo as he returns to the Kingdom of Fantasy for a third amazing adventure! In this 320-page, full-color hardcover adventure, Geronimo returns to the Kingdom of Fantasy when he learns that the Kingdom has fallen under an endless, freezing winter and the Queen of the Fairies is in danger. Once there, Geronimo explores fantastical new lands and travels on a magical talking ship. Can Geronimo extinguish a threatening volcano in time to restore peace and springtime to the Kingdom of Fantasy? He is put to the test on this extraordinary quest!
Young Apache Goyahkla and his friend play games in their village that will prepare him for his role as a hunter and warrior-- and the place he will hold in history as Geronimo, fighter for the rights of his people.
The ever-increasing population of older adults residing in nursing homes and long-term care communities, as reflected in numerous demographic studies, point out a clear need for geropsychologists i.e., trained specialists in the field of aging and mental health, to meet the needs of this nation's older adults. This book will provide a needed resource for psychologists working in long-term care settings and those who wish to do so. Key outcomes include the provision of high quality psychological services for this important but neglected sector namely, people living in nursing homes, assisted living communities and other LTC settings. This text will be of great value to psychologists currently working in long-term care settings who have had graduate work in geropsychology, yet desire more in-depth and practical training. A second audience includes those individuals who may have a leaning towards expanding their professional activities in long-term care and are seeking additional preparation before doing more work with older adults. A third group is comprised of those individuals who are not psychologists, yet have had some training and coursework in aging and mental health.
From celebrated entertainer Michael Feinstein comes a beautifully illustrated account of the lives and legacies of the Gershwins--told through stories of twelve of their greatest songs. In addition to a CD, this special edition has a slip cover and comes with removable sheet music.The "Ambassador of the Great American Songbook" Michael Feinstein was just twenty years old when he got the chance of a lifetime: a job with his hero, Ira Gershwin. During their six-year partnership, the two became close friends. Feinstein blossomed under Gershwin's mentorship and Gershwin was reinvigorated by the younger man's zeal for his and his brother George's legacy. Now, in The Gershwins and Me, the only book of its kind, Michael Feinstein shares unforgettable stories and reminiscences from the music that defined American popular song, along with rare Gershwin memorabilia he's collected through the years. From "Strike Up the Band" to "Love Is Here to Stay," each of the twelve chapters highlights one of the Gershwins' classic songs, exploring the brothers' lives, illuminating what the music meant to them, and telling the stories of how their iconic tunes came to life. Throughout the star-studded narrative, Feinstein unfolds the moving chronicle of his own life with the Gershwins, describing his vision for their enduring presence today. No other writer could give us such an authoritative inside perspective on these titans of American culture--and no other writer could include such a soulful collection of music as the accompanying CD packed with Feinstein's original recordings of the twelve songs. A timeless classic and the definitive account of the Gershwins and their legacy, The Gershwins and Me will having you humming with every turn of the page.
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