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Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters.This book:Provides a comprehensive account of inference techniques in systems biology.Introduces classical and Bayesian statistical methods for complex systems.Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems.Discusses various applications for statistical systems biology, such as gene regulation and signal transduction.Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies.Presents an in-depth presentation of reverse engineering approaches.Provides colour illustrations to explain key concepts.This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.
What issues and trends affect higher education and student affairs today? In this fully updated handbook, leading experts discuss the answer to this and other essential questions. They provide a definitive reference for student affairs professionals at all levels of administration and management. The handbook offers specific, practical advice as well as broad approaches to planning and problem solving. It contains modernized discussions on such critical topics as institutional mission, institutional governance, understanding campus environments, finance and budgeting, assessment, program planning, staff selection, training and evaluation, and much more.
This book is a comprehensive guide to the International Phonetic Alphabet, widely used for over a century to transcribe the sounds of languages. The Handbook is in three parts: Part I contains an introduction to phonetic description and exemplification of the use of phonetic symbols; Part II consists of twenty-nine "Illustrations" of the application of the International Phonetic Alphabet to a range of languages; and Part III covers speech pathology, computer codings, and the history of the IPA. This is an essential reference work for phoneticians and linguists more generally.
Widely regarded as the definitive reference, this volume comprehensively examines the psychological processes associated with religion and spirituality. Leading scholars from multiple psychological subdisciplines present developmental, cognitive, social psychological, cultural, and clinical perspectives on this core aspect of human experience. The forms and functions of religious practices and rituals, conversion experiences, and spiritual struggles are explored. Other key topics include religion as a meaning system, religious influences on prosocial and antisocial behavior, and connections to health, coping, and psychotherapy.New to This Edition*Two chapters on cross-cultural issues.*Chapters on spiritual goals, emotional values, and mindfulness.*Reflects significant theoretical and empirical developments in the field.*Many new authors and extensively revised chapters.*Robust index amplifies the volume's usefulness as a reference tool.
The Handbook of the Sociology of Health, Illness & Healing advances the understanding of medical sociology by identifying the most important contemporary challenges to the field and suggesting directions for future inquiry. The editors provide a blueprint for guiding research and teaching agendas for the first quarter of the 21st century. In a series of essays, this volume offers a systematic view of the critical questions that face our understanding of the role of social forces in health, illness and healing. It also provides an overall theoretical framework and asks medical sociologists to consider the implications of taking on new directions and approaches. Such issues may include the importance of multiple levels of influences, the utility of dynamic, life course approaches, the role of culture, the impact of social networks, the importance of fundamental causes approaches, and the influences of state structures and policy making.
Tunnel engineering is one of the oldest, most interesting but also challenging engineering disciplines and demands not only theoretical knowledge but also practical experience in geology, geomechanics, structural design, concrete construction, machine technology, construction process technology and construction management. The two-volume "Handbuch des Tunnel- und Stollenbaus" has been the standard reference work for German-speaking tunnellers in theory and practice for 30 years. The new English edition is based on a revised and adapted version of the third German edition and reflects the latest state of knowledge. The book is published in two volumes, with the second volume covering both theoretical themes like design basics, geological engineering, structural design of tunnels and monitoring instrumentation, and also the practical side of work on the construction site such as dewatering, waterproofing and scheduling as well as questions of tendering, award and contracts, data management and process controlling. As with volume I, all chapters include practical examples.
The purpose of this handbook is to introduce the reader to Christian concepts from the perspective of U.S. marginalized communities. It explores the interrelationship between religion, community, and culture in the social context of different marginalized groups, specifically those rooted in the African American, Amerindian, Asian American, feminist, gay/lesbian, and Hispanic experiences, and their impact on the development of U.S. theologies of liberation. The handbook gives attention to the history, nature, sources, and development of these theologies and the theologians who contributed to their formation. Of particular interest is how Handbook of U.S. Theologies of Liberation clearly distinguishes both the differences and similarities between these U.S. theologies and their Latin American counterparts.
Describes everything needed for businesses to set up and begin conducting usability tests.
This is the first definitive textbook on veterinary communication, written specifically for students and veterinary professionals by a group of international experts. Communication is a core clinical skill, and is now taught as a compulsory part of most veterinary degree courses. Good communication is crucial to the veterinarian-client-patient relationship, to patient health and ultimately to the success of any veterinary business.The book covers all the key areas of communication including: the basic framework for the veterinary consultation; professional, ethical and legal aspects; communication with clients and colleagues; and coping with end-of-life and other difficult situations. It combines the most up-to-date research with a wealth of practical information, such as:Real-life case studies to help you apply your learning to real scenariosSimple step-by-step guidelines showing you how to deal with specific situationsExamples of written resources you can use in practiceThis valuable textbook has been written and edited by a carefully chosen group of specialists, comprising veterinary communication lecturers, veterinary practitioners, training managers and counsellors.
Handbook of War Studies III is a follow-up to Handbook of War Studies I (1993) and II (2000). This new volume collects original work from leading international relations scholars on domestic strife, ethnic conflict, genocide, and other timely topics. Special attention is given to civil war, which has become one of the dominant forms - if not the dominant form - of conflict in the world today.
This practical handbook provides a clear and comprehensive evidence-based guide to the care of women in primary care, intended for general and family practitioners, nurses, physician assistants, and all those who practise primary care of women. It emphasizes preventive and well-woman care throughout the life-cycle of a woman, including sexuality, contraception, medical care in pregnancy, and psychological and important medical concerns. This new edition, revised and updated throughout with several new contributing authors, incorporates the latest evidence and research-findings on a wide range of problems for which women seek medical guidance. There is an expanded section on menstrual problems and menopause-associated conditions, including clear guidance on the use of hormone replacement therapy.
This book addresses the developing field of Work Disability Prevention. Work disability does not only involve occupational disorders originating from the work or at the workplace, but addresses work absenteeism originating from any disorder or accident. This topic has become of primary importance due to the huge compensation costs and health issues involved. For employers it is a unique burden and in many countries compensation is not even linked to the cause of the disorder. In the past twenty years, studies have accumulated which emphasize the social causes of work disability. Governments and NGOs such as the World Bank, the International Labor Organization, and the Organization for Economic Cooperation and Development have produced alarming reports on the extent of this problem for developed and developing countries. However, no comprehensive book is presently available to help them address this emerging field where new knowledge should induce new ways of management.
For more than twenty years, Victor Hamilton's handbook has been introducing students to the Pentateuch. In this substantially revised second edition, Hamilton moves chapter by chapter (rather than verse by verse) through the Pentateuch. He examines the content, structure, and theology and provides useful commentary on overarching themes and connections between Old Testament texts. For those who wish to do additional research, each chapter is appended with a bibliography of recent, relevant scholarship.
An indispensable guide to making the transition to dual IFRS/GAAP financial reportingU.S. financial reporting will undergo an unprecedented level of change within the next several years. U.S. companies face a convergence between U.S. GAAP and IFRS, affecting several major accounting standards--most notably in the areas of leasing, revenue recognition, and financial instruments. It is imperative that U.S. companies understand these major changes and their business and operational implications. The IFRS U.S. GAAP Dual Reporting Handbook to First-Time Adoption offers a comprehensive treatment of both the principles and techniques of dual reporting under IFRS/U.S. GAAP, while exploring the practical implications for accounting professionals of reporting under both sets of standards.Takes an operating approach to the implementation and application of the dual standardsDraws upon the author's extensive firsthand experience to dispel uncertainty and offer decision makers expert technical assistanceDefines systemic changes businesses will need to make to accommodate IFRS standardsCompares the two bodies of standards item-by-item and identifies solutions under one set of standards to issues arising under the otherExplores the strategic impact of structuring a company for IFRS transitionIn addition to covering the full range of critical issues surrounding adopting IFRS, this indispensable handbook is a rich resource of dual reporting tools, including financial statement formats, charts of accounts, accounting check-lists, reconciliation schedules, and operating manuals.
The Perfect Cocktail, Any Time! Enjoy classic cocktails in true pre-Prohibition style--throughout the day! Inside you'll find recipes for the perfect brunch cocktails, refreshing afternoon cocktails and invigorating happy hour drinks, plus dinner cocktails perfect for pairing with meals, and relaxing nightcaps. Each cocktail recipe is carefully crafted to create the perfect balance of the sweet, the sour, the bitter and the spirit, producing a delicious drink every time. The secret is using fresh, house-made mixers. You'll find complete instructions for making your own simple syrups, bitters, liqueurs and cordials using unique ingredients such as cardamom, cilantro, rosemary, lavender, eucalyptus, five-spice and more. Plus you'll learn the fascinating histories of classic pre-Prohibition cocktails such as the very vintage Sherry Cobbler and the silky smooth Ramos Gin Fizz and try some new Prohibition-inspired cocktails such as the Kitty Burke and Bees in Kilts. With more than 100 recipes inside you're sure to discover your new favorite drink.
PARKER PRESCOTT IS an ice princess. Cold, aloof, a snob. At least, that's what everyone says on Marion Hennessey's blog. And everyone reads Marion Hennessey's blog. Parker Prescott is a middle child. She's the good one, the dependable one, the one her parents trust. Well . . . she used to be. Parker Prescott's parents want her to break up with her boyfriend. But she already did, two weeks ago. And then she realized it was a mistake. He came over. He had the handcuffs in his pocket. Everything went downhill from there. Sort of. Parker Prescott's world is changing and she no longer knows who she is. Does anyone? From the Hardcover edition.
A droll biography reveals the high notes--and the low notes- in the life of the world's foremost composer of Baroque music. This is not your usual picture book biography. Nor was George Frideric Handel your everyday eighteenth-century composer. This witty and yet rigorously researched and accessible biography captures Handel's essential spirit--from a child who smuggled a clavichord into the attic to play music against his father's orders to a young man who imported forty-five pounds of mountain snow to chill wine for a gala--as well as his remarkable, enduring musical triumphs. But M. T. Anderson also shows Handel's struggles and chronicles the illness, ill fortune, and despair that led to his greatest achievement, the Messiah.
Felt from a distance, Susan and David's attraction to each other was powerful, but will their stubborn prejudices solidify their loathing, or give way to their passion? Susan Anderson has despised David Lane ever since their first meeting. He enraged her with his verbal barbs and cold contempt; he had no idea who she was or what her true relationship had been with his father, Peter, who left her his Maine beach house. David assumed Susan was a vulture, preying on his old man for his wealth. And Susan was in no mood to defend herself against the charges of such a pigheaded man. But when a severe storm strands them alone in the beach house, David and Susan's mutual dislike for each other--and their fierce attraction to each other--is brought to a head. This ebook features an illustrated biography of Heather Graham including rare photos from the author's personal collection.
After seven years of marriage, the beautiful Lady Brenda Last has grown bored with life at Hetton Abbey, the Gothic mansion that is the pride and joy of her husband, Tony. She drifts into an affair with the shallow socialite John Beaver and forsakes Tony for the Belgravia set. In a novel that combines tragedy, comedy, and savage irony, Evelyn Waugh indelibly captures the irresponsible mood of the "crazy and sterile generation" between the wars.
A Handful of Quiet presents one of the best known and most innovative meditation practices developed by Thich Nhat Hanh as part of the Plum Village community's practice with children. Pebble meditation is a playful and fun activity that parents and educators can do with their children to introduce them to meditation. It is designed to involve children in a hands-on and creative way that touches on their interconnection with nature. Practicing pebble meditation can help relieve stress, increase concentration, nourish gratitude, and can help children deal with difficult emotions.A Handful of Quiet is a concrete activity that parents and educators can introduce to children in school settings, in their local communities or at home, in a way that is meaningful and inviting. It includes four full-color meditation cards with short mindfulness poems that are recited during the meditation. Any adult wishing to plant seeds of peace, relaxation, and awareness in children will find this unique meditation guide helpful. Children can also enjoy doing pebble meditation on their own.Beautiful color illustrations by Wietske Vriezen, illustrator of Planting Seeds (ISBN-13: 978-1-935209-80-5) and Mindful Movements (978-1-888375-79-4).
In the first of a sweeping Western romance series written by a Rita Award-winning author, a woman tries to make her way into the rodeo world--and lassos the affections of a handsome cowboy. Shallie had to make her way in rodeo, a man's world, and Hunt McIver's help was invaluable to her. But the man himself remained a mystery. Why would he help a woman whose motives he didn't trust? Yet together they warmed the western nights and built a dream beneath a sky as wide and beautiful as the love that bloomed between them....
Anthology of poems by Padma Sachdev, translated from Dogri and Hindi.
The handgun is no longer a product purchased and used in an unaltered state. A vast assortment of accessories, including high performance sights, weapon lights and laser aiming devices have not only enhanced the handgun, they have changed the methodology and mindset of personal protection. In Handgun Training for Personal Protection: How to Choose & Use the Best Sights, Lights, Lasers & Ammunition, the first comprehensive book of its kind, shooting expert Richard A. Mann explores the world of these exciting advances and what they mean to your self-defense practices. Inside you'll find: How lasers, lights and sights are valuable in a defensive situation. Techniques for training with lasers, lights and sights that develop and reinforce effective use of the handgun in a defensive situation. A comprehensive explanation of sighting tool functionality. Information on the latest equipment options. "This book belongs in every shooter's library. Mann provides a practical, hands-on guide to working with your handgun and the equipment that goes with it. Along the way, common misconceptions are corrected, and often neglected topics are explained. This book will become your go-to reference." ~Il Ling New, Gunsite Instructor "You will read it again and again, as your defensive ability and understanding grow. Take it to heart; it just might save your life." ~Sheriff Jim Wilson, Senior Field Editor, NRA Publications
What s better than small treats? Eating with your hands! This enticing cookbook delivers on both counts in one adorable package. Pie-lovers everywhere will be thrilled to find their favorite recipes plus fabulous new creations. Savory pies also make an appearance: grab a Bacon, Egg, and Cheese Breakfast Pie on the way out the door in the morning! Ideal for beginning and seasoned bakers alike (a chapter on crusts offers all the instruction anyone needs to make delicious, flaky pastry with ease!), Handheld Pies proves that good things definitely come in small packages.
Things break all the time. Day breaks, waves break, voices break. Promises break. Hearts break. Every expectant parent will tell you that they don't want a perfect baby, just a healthy one. Charlotte and Sean O'Keefe would have asked for a healthy baby, too, if they'd been given the choice. Instead, their lives are made up of sleepless nights, mounting bills, the pitying stares of "luckier" parents, and maybe worst of all, the what-ifs. What if their child had been born healthy? But it's all worth it because Willow is, well, funny as it seems, perfect. She's smart as a whip, on her way to being as pretty as her mother, kind, brave, and for a five-year-old an unexpectedly deep source of wisdom. Willow is Willow, in sickness and in health. Everything changes, though, after a series of events forces Charlotte and her husband to confront the most serious what-ifs of all. What if Charlotte should have known earlier of Willow's illness? What if things could have been different? What if their beloved Willow had never been born? To do Willow justice, Charlotte must ask herself these questions and one more. What constitutes a valuable life? Emotionally riveting and profoundly moving, Handle with Care brings us into the heart of a family bound by an incredible burden, a desperate will to keep their ties from breaking, and, ultimately, a powerful capacity for love. Written with the grace and wisdom she's become famous for, beloved #1 New York Times bestselling author Jodi Picoult offers us an unforgettable novel about the fragility of life and the lengths we will go to protect it.
Select your format based upon: 1) how you want to read your book, and 2) compatibility with your reading tool. To learn more about using Bookshare with your device, visit the "Using Bookshare" page in the Help Center.
Here is an overview of the specialized formats that Bookshare offers its members with links that go to the Help Center for more information.
- Bookshare Web Reader - a customized reading tool for Bookshare members offering all the features of DAISY with a single click of the "Read Now" link.
- DAISY (Digital Accessible Information System) - a digital book file format. DAISY books from Bookshare are DAISY 3.0 text files that work with just about every type of access technology that reads text. Books that contain images will have the download option of ‘DAISY Text with Images’.
- BRF (Braille Refreshable Format) - digital Braille for use with refreshable Braille devices and Braille embossers.
- MP3 (Mpeg audio layer 3) - Provides audio only with no text. These books are created with a text-to-speech engine and spoken by Kendra, a high quality synthetic voice from Ivona. Any device that supports MP3 playback is compatible.
- DAISY Audio - Similar to the Daisy 3.0 option above; however, this option uses MP3 files created with our text-to-speech engine that utilizes Ivona's Kendra voice. This format will work with Daisy Audio compatible players such as Victor Reader Stream and Read2Go.