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"It began with a promising cancer drug, the brainchild of a gifted researcher, and grew into an insider trading scandal that ensnared one of America's most successful women. The story of ImClone Systems and its "miracle" cancer drug, Erbitux, is the quintessential business saga of the late 1990s. It's the story of big money and cutting-edgescience, celebrity, greed, and slipshod business practices; the story of biotech hype and hope and every kind of excess. At the center of it all stands a single, enigmatic figure named Sam Waksal. A brilliant, mercurial, and desperate-to-be-liked entrepreneur, Waksal was addicted to the trappings of wealth and fame that accrued to a darling of the stock market and the overheated atmosphere of biotech IPOs. At the height of his stardom, Waksal hobnobbed with Martha Stewart in New York and Carl Icahn in the Hamptons, hosted parties at his fabulous art-filled loft, and was a fixture in the gossip columns. He promised that Erbitux would "change oncology," and would soon be making $1 billion a year. But as Waksal partied late into the night, desperate cancer patients languished, waiting for his drug to come to market. When the FDA withheld approval of Erbitux, the charming scientist who had always stayed just one step ahead of bankruptcy panicked and desperately tried to cash in his stock before the bad news hit Wall Street. Waksal is now in jail, the first of the Enron-era white-collar criminals to be sentenced. Yet his cancer drug has proved more durable than his evanescent profits. Erbitux remains promising, the leading example of a new way to fight cancer, and patients and investors hope it will be available soon.
Julia Child singlehandedly created a new approach to American cuisine with her cookbook Mastering the Art of French Cooking and her television show The French Chef, but as she reveals in this bestselling memoir, she was not always a master chef. Indeed, when she first arrived in France in 1948 with her husband, Paul, who was to work for the USIS, she spoke no French and knew nothing about the country itself. But as she dove into French culture, buying food at local markets and taking classes at the Cordon Bleu, her life changed forever with her newfound passion for cooking and teaching. Julia's unforgettable story - struggles with the head of the Cordon Bleu, rejections from publishers to whom she sent her now-famous cookbook, a wonderful, nearly fifty-year long marriage that took them across the globe - unfolds with the spirit so key to her success as a chef and a writer, brilliantly capturing one of the most endearing American personalities of the last fifty years.From the Trade Paperback edition.
Now in paperback from the bestselling coauthor with Julia Child of My Life in France "a balanced and insightful assessment of what could emerge as the dominant issue in decades ahead" (Associated Press)--the fate of fresh water in the twenty-first century.With The Ripple Effect, Alex Prud'homme has changed the way we think about the water we drink. Inspired by an interest in our worldwide obsession with bottled water, Prud'homme undertook an ambitious quest to understand the evolving story of freshwater. What he found was shocking: as the climate warms and world population grows, demand for water has surged, but supplies of fresh water are static or dropping, and new threats to water quality appear every day. The questions he sought to answer were urgent: Will there be enough water to satisfy demand? What are the threats to its quality? What is the state of our water infrastructure--both the pipes that bring us fresh water and the levees that keep it out? How secure is our water supply from natural disasters and terrorist attacks? Can we create new sources for our water supply through scientific innovation? Is water a right like air or a commodity like oil--and who should control the tap? Like Daniel Yergin's seminal classic The Prize: The Epic Quest for Oil, Money, & Power, The Ripple Effect is a masterwork of investigation and a dramatic narrative, spanning from the alleged murder of a water scientist in New Jersey to the epic confrontation between salmon fishermen and copper miners in Alaska. The Ripple Effect is a major achievement and will change our understanding of the importance of water forever. el Pollan has changed the way we think about the food we eat; Alex Prud'homme will change the way we think about the water we drink. Informative and provocative, The Ripple Effect is a major achievement.
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