Microbial Biochemistry

Synopsis

This bookfocusses on microbial physiology, biochemistry and genetics and provides thereader with detailed information on a number of microbial pathways. Insightinto microbial biochemistry have allowed for the formulation of concepts thathave turned out to be important in the study of higher organisms. In thefirst section, the principles of bacterial growth are given, as well as adescription of the different layers that enclose the bacterial cytoplasm, andtheir role in obtaining nutrients from the outside media through differentpermeability mechanism, which are described in detail. A chapter is devoted toallostery, which is indispensable for the comprehension of many regulatorymechanisms described throughout the book. The secondsection analyses the mechanisms by which cells obtain the energy necessary fortheir growth; Glycolysis, the pentose phosphate pathway, the tricarboxylic andthe anaplerotic cycles. Two chapters are devoted to classes of microorganismsrarely dealt with in textbooks, namely the Archaea, mainly the methanogenicbacteria, and the methylotrophs. Eight chapters describe the principles ofregulation at the transcriptional level, with the necessary knowledge of themachineries of transcription and translation. The next fifteenchapters deal with the biosynthesis of the cell building blocks, amino acids,purine and pyrimidine nucleotides and deoxynucleotides, water-soluble vitaminsand coenzymes, isoprene and tetrapyrrole derivatives and vitamin B12. The twolast chapters are devoted to the study of protein-DNA interactions and to theevolution of biosynthetic pathways. The considerable advances made in the lastthirty years in the field by the introduction of gene cloning and sequencingand by the exponential development of physical methods such as X-raycrystallography, nuclear magnetic resonance and cryo-electron microscopy havehelped in presenting microbial metabolism as a highly multidisciplinary fieldof study.

Copyright:

2016

Book Details

Book Quality:

Publisher Quality

ISBN-13:

9789401775793

Publisher:

Springer Netherlands, Dordrecht

Date of Addition:

11/16/16

Copyrighted By:

Springer

Adult content:

No

Language:

English

Has Image Descriptions:

No

Categories:

Nonfiction, Science

Submitted By:

Bookshare Staff

Usage Restrictions:

This is a copyrighted book.