Redox-Active Therapeutics

Synopsis

This essentialvolume comprehensively discusses redox-active therapeutics, focusingparticularly on their molecular design, mechanistic, pharmacological andmedicinal aspects. The first section of the book describes the basicaspects of the chemistry and biology of redox-active drugs and includes a briefoverview of the redox-based pathways involved in cancer and the medical aspectsof redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerativediseases, pain, radiation injury and radioprotection (such as of brain, lungs, headand neck and erectile function) and neglected diseases (e. g. , leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, whichinclude porphyrins, salens, nitrones, and most notably metal-containing (e. g. ,Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations withnanomaterials and quantum dots. Numerous illustrations, tablesand figures enhance and complement the text; extensive references to relevantliterature are also included. Redox-Active Therapeutics is an invaluable addition to Springer's OxidativeStress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate studentsinterested in understanding and exploring the Redoxome--the organism redoxnetwork--as an emerging frontier in drug design, redox biology and medicine.

Copyright:

2016

Book Details

Book Quality:

Publisher Quality

ISBN-13:

9783319307053

Publisher:

Springer International Publishing, Cham

Date of Addition:

03/22/17

Copyrighted By:

Springer

Adult content:

No

Language:

English

Has Image Descriptions:

No

Categories:

Nonfiction, Science

Submitted By:

Bookshare Staff

Usage Restrictions:

This is a copyrighted book.