Recent Trends in Antifungal Agents and Antifungal Therapy

By: Amit Basak and Ranadhir Chakraborty and Santi M. Mandal

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Synopsis: Fungalinfections have taken a new spectrum due to the increased incidence ofmulti-drug resistant fungal pathogens. Freedom of choice for drugs to treatfungal infections is also narrow because of lesser probability of discovering drugsthat would bypass affecting human cells and target fungal cells producing fewerside effects in patients. An approach has gained prominence in research is tolook for bioactive antifungal compounds from natural to synthetic sources. Itis necessary to discover new classes of antifungals to control the recentemergence of multi-drug resistant fungal infections. This book proposed adetails top to bottom outline of antifungal compounds derived naturally orsynthetically. The details of their modifications or synthetic analogues havebeen described, helpful to understand the structure-activity relationship whichleads to new compound development in antifungal chemotherapy. Each chapterbegins with a comprehensive, top-bottom in-depth discussion of antifungalagents with updated bibliographic references. This compendium will serve as acompanion not only for Scientists, Researchers, and Professors, MedicalPractitioners but also a valuable reference text for the university students.