Introduction to Surgical Trials

By: Stephen Lyman and Olufemi R. Ayeni and Jason L. Koh and Norimasa Nakamura and Jón Karlsson

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Synopsis: Filling a gap in literature, this book examines surgical trials with a special focus on the underlying principles, challenges, and best practices to successfully conduct rigorous surgical research.While randomized controlled trials (RCTs) remain the gold standard for evaluation of the safety and efficacy of most medical interventions, they are particularly difficult to implement successfully in the context of surgery. As a result, recruitment rates are often extremely low, crossover from non-operative to operative is common, and patients randomly allocated to surgery often simply decline to have the procedure. All of these challenges call into question the recent generalizability and fundamental quality of traditional surgical RCTs. As such, this book explores advanced alternative trial design methods and describes the current regulatory environment around the world. Designed as a practical guide, it is a valuable tool for surgeons, epidemiologist and biostatisticians involved in this challenging field.

Book Quality:: Publisher Quality
ISBN-13:: 9783031775635
Related ISBNs:: 9783031775628
Publisher:: Springer Nature Switzerland
Date of Addition:: 03/29/25
Copyrighted By:: ISAKOS
Adult content:: No
Language:: English
Has Image Descriptions:: No
Categories:: Nonfiction, Computers and Internet, Mathematics and Statistics, Medicine
Submitted By:: Bookshare Staff
Usage Restrictions:: This is a copyrighted book.
Edited by:: Stephen Lyman
Edited by:: Olufemi R. Ayeni
Edited by:: Jason L. Koh
Edited by:: Norimasa Nakamura
Edited by:: Jón Karlsson