Disseminating In Silico and Computational Biological Research: Navigating Benefits and Risks: Proceedings of a Workshop

By: and and and and

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Synopsis
The United States and other countries have developed policies, guidance, and safeguards aimed at reducing risks associated with dual-use research of concern (DURC) and research involving pathogens with enhanced pandemic potential (PEPP). These efforts have focused primarily on overseeing research conducted in physical laboratory settings where biological materials are directly handled, commonly referred to as “wet labs.” Research conducted in computational environments (“in silico” research) also plays an essential role in advancing scientific knowledge and enhancing capabilities such as predictive modeling, data analysis, and system simulation, and also may fall under the DURC and PEPP research categories. In response to recent advances in generative artificial intelligence (AI), computational modeling tools, and approaches in biological research, the scientific community has focused on the benefits and potential biosecurity risks associated with communicating studies that use in silico methodologies to understand and design biological systems. To explore existing policies and guidance on DURC and research involving PEPP and their relevance to in silico research, the National Science Foundation sponsored a workshop hosted by the National Academies of Sciences, Engineering, and Medicine entitled Navigating the Benefits and Risks of Publishing Studies of In Silico Modeling and Computational Approaches of Biological Agents and Organisms. The hybrid workshop was held April 3-4, 2025, and convened 250 participants from government, industry, academia, and nonprofit and philanthropic sectors, as well as scientific publishing and policy-focused organizations. Presentations and discussion examined the criteria that could be considered to assess the benefits and risks of in silico research and possible strategies to facilitate the responsible dissemination of this research. This publication summarizes the presentation and discussion of the workshop.
Copyright:
2025

Book Details

Book Quality:
Publisher Quality
ISBN-13:
9780309994354
Publisher:
The National Academies Press
Date of Addition:
Copyrighted By:
the National Academy of Sciences
Adult content:
No
Language:
English
Has Image Descriptions:
No
Categories:
Nonfiction
Submitted By:
Bookshare Staff
Usage Restrictions:
This is a copyrighted book.

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