Exosomes and Extracellular Vesicles: Analytical Challenges and Biological Implications

By: R. Kenneth Marcus and David Lubman

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Synopsis: This book introduces a comprehensive overview of exosomes in biology for their roles in cell signalling. This edited collection of works by leading extracellular vesicle (EV) scientists and medical professionals introduces readers to various aspects of the rapidly expanding field of exosomes and extracellular vesicles. Contributing authors pay close attention to the analytical techniques and methods in this field, with a particular focus on mass spectrometry. The chapters cover areas including biological and therapeutic significance, novel methods for isolation of these EVs from human body fluids and cell culture media, and examples of their use in biomarker research and in therapeutic applications. This book provides an expert analysis of the latest advances in this field, including the isolation of EVs and their various applications. The highlighted chapters provide readers a broad overview of the relevant analytical challenges in EV science. This book is of interest to both scientific researchers and medical practitioners, as well as graduate students in diverse areas of fundamental biology, physiology, medicine, pharmaceuticals, and analytical chemistry.