Microwaves in Organic and Medicinal Chemistry

By: Alexander Stadler and Raimund Mannhold and Gerd Folkers and Hugo Kubinyi and Doris Dallinger and C. Oliver Kappe

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Synopsis: Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed,almost doubling the amount of chemical information with an additional volume.As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation andequipment. The main part of the book then goes on to systematically survey the complete range of published microwave-assisted synthesismethods from their beginnings in the 1990s to mid-2011, drawing on data from more than 5,000 reports and publications. Throughout, thefocus is on those reactions, reagents and reaction conditions that work, and that are the most relevant for medicinal and natural productschemistry. A much expanded section is devoted to combinatorial, highthroughput and flow chemistry methods.