Transition Metal-Catalyzed Couplings in Process Chemistry
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- Synopsis
- This one-stop reference source is the first on this new and exciting technology to focus on case studies of large-scale industrial applications, presenting the information and facts that are otherwise hard to find in the current literature.Authors from Pfizer, Merck, DSM, Novartis, Amgen, and Astra Zeneca, among others, use case studies to showcase project evolution from inception to early and late development, including commercial routes where applicable. Each case study details at least one transition metal-catalyzed cross-coupling step, with special emphasis on lessons learned from their implementation. The important issue of metal removal from the reaction mixtures to meet specifications and the different technologies available to accomplish this goal are also addressed. Finally, a small section covers novel technologies for cross-coupling with high future potential for applications on a large scale, such as metal removal on large scale, microwave and flow chemistry, as well as green chemistry.Of great interest to chemists working in the pharmaceutical, agrochemical and fine chemical industries, but also for every synthetic chemist working in academia.
- Copyright:
- 2013
Book Details
- Book Quality:
- Publisher Quality
- ISBN-13:
- 9783527658923
- Related ISBNs:
- 9783527332793
- Publisher:
- Wiley
- Date of Addition:
- 06/21/14
- Copyrighted By:
- John Wiley & Sons
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Nonfiction, Science
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.