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Our fates lie in our genes and not in the stars, said James Watson, co-discoverer of the structure of DNA. But Watson could not have predicted the scale of the industry now dedicated to this new frontier. Since the launch of the multibillion-dollar Human Genome Project, the biosciences have promised miracle cures and radical new ways of understanding who we are. But where is the new world we were promised?In Genes, Cells, and Brains, feminist sociologist Hilary Rose and neuroscientist Steven Rose take on the bioscience industry and its claims. Examining the rivalries between public and private sequencers,the establishment of biobanks, and the rise of stem cell research, they ask why the promised cornucopia of health benefits has failed to emerge. Has bioethics simply become an enterprise? As bodies become increasingly commodified, perhaps the failure to deliver on these promises lies in genomics itself.
In light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries--such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna--challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms. Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences. Contributors. Thomas Brglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Mller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf
During his seven-month stay in a Trappist monastery, Henri Nouwen had a unique opportunity to explore crucial issues of the spiritual life and discover "a quiet stream underneath the fluctuating affirmations and rejections of my little world." Nouwen participated fully in the daily life of the Abbey of the Genesee in upstate New York -- in work and in prayer. From the early weeks in the abbey -- dominated by conflicting desires and concerns -- to the final days of Advent, when he finds a new sense of calm expectation, Nouwen never loses his critical honesty. Insightful, compassionate, often humorous, always realistic, The Genesee Diary is both an inspiration and a challenge to those who are in search of themselves."The Genesee Diary beautifully lifts the heart and mind to God."--Christianity Today"This is an extraordinary account of a man seeking inner peace and total commitment to God... a fine portrait of cloistered life, a beautifully written account of one man's soul-searching."--Publisher's Weekly
Arnold Toynbee writes: IN the first volume of A Study of History, I start by searching for a unit of historical study that is relatively self-contained and is therefore more or less intelligible in isolation from the rest of history. I was led into this quest by finding myself dissatisfied with the present-day habit of studying history in terms of national states. These seemed, and still seem, to me to be fragments of something larger, and I found this larger and more satisfying unit of study in a civilization. The history of the United States, for instance, or the history of Britain, is, as I see it, a fragment of the history of Western Christendom or the Western Christian World, and I believe I can put my finger on a number of other societies, living or extinct, that are of the same species. Examples of other living civilizations besides the Western Civilization are the Islamic and the Civilization of Eastern Asia, centring on China. Examples of extinct civilizations are the Greco-Roman and the Ancient Egyptian. This practice of dealing in civilizations instead of nations is taken for granted by orientalists, ancient-historians, archaeologists, and anthropologists. The carving-up of a civilization into pieces labelled 'nations' is, I believe, something peculiar to students of modern Western history, and, with them too, this present practice of theirs is only recent. Down to the beginning of the eighteenth century, the classic works of Western historians took for their field the whole history of Western Christendom or even the whole history of the World from the Creation to the Last Judgement. Other books in this series are available from Bookshare.
In this highly acclaimed translation, Stephen Mitchell conveys in English the simplicity, dignity and powerful earthiness of the original Hebrew. More than just interpreting it, he also separates stories that were combined by scribes centuries after they were written, explaining their sources and omitting all verses that are recognized as scribal additions. Like removing coat after coat of lacquer from a once-vibrant masterpiece, this allows readers to appreciate the clarity of the original tales. Genesis is an extraordinarily beautiful book that is accessible in a way that no other translation has ever been. It will shed new light on readers' understanding of this seminal work of sacred scripture.
The Hive: a subterranean genetic research facility owned and operated by Umbrella, an immensely powerful corporation with interests in everything from human longevity to biowarfare. With computerized defenses and heavily armed human backup, the Hive is impregnable and invulnerable. Or so Umbrella believes. But something has gone fatally wrong. The Hive has lost containment of its most lethal and horrific creation: a virus that kills and reanimates human life, reducing the entire facility staff of five hundred men and women to mindless creatures with a single driving force -- hunger. And the key to stopping them rests with one young woman who cannot even remember who she is.
This book invites readers to reconsider what they think they know about the opening chapters of the Book of Genesis, from the creation of the world, through the Garden of Eden, Cain and Abel, the Flood, and the Tower of Babel, to the introduction of Abraham. Edwin M. Good offers a new translation of and literary commentary on these chapters, approaching the material as an ancient Hebrew book. Rather than analyzing the chapters in light of any specific religious position, he is interested in what the stories say and how they work as stories, indications in them of their origins as orally performed and transmitted, and how they do and do not connect with one another. Everyone, from those intimately familiar with Genesis to those who have never read it before, will find something new in Genesis 1-11: Tales of the Earliest World.
In this groundbreaking book, physicist Gerald Schroeder takes on skeptics from both sides of the cosmological debate, arguing that science and the Bible are not at odds concerning the origin of the universe.From the Trade Paperback edition.
Following on the success and popularity of Genesis Wave: Books One, Two, and Three, John Vornholt pulls together a group of Star Trek heroes with a mission unlike any other!The passing of the Genesis Wave has damaged hundreds of worlds in the newly named "Genesis Sector," and chaos reigns throughout that area of space. Each world has been changed in different ways, and a group of extraordinary men and women -- some old friends, some new faces -- have been assigned the job of getting the devastated planets back on their feet. Their first job: To resettle an entire displaced alien race on its altered home planet, where the dead come back to life, microbes have reached gigantic size, and the new ecology taking over the world is one not fit for man nor genetically altered beast. . . .
Genesis is a book of origins--the origin of the universe, the origin of life and the origin of man. It places man in his cosmic setting, shows his particular uniqueness, explains his wonder and his flaws, and begins to trace the flow of human history through space and time. Many today, however, view this book as a collection of myths, useful for understanding the Hebrew mind, perhaps, but certainly not a record of what really happened. Dr. Francis A. Schaeffer challenges that view and shows how the first eleven chapters of Genesis stand as a solid, space-time basis for answering the tough questions posed by modern man.
More than three decades ago, Dr. Kathleen Sainsbury's archaeologist parents were murdered at an ancient excavation site in Iraq. Now the gifted biologist stands on the brink of a miraculous breakthrough: the discovery of a gene that could extend a human life by hundreds of years. But at the moment of her greatest triumph, a mysterious phone call reveals a hidden truth that draws chaos and violence once again into Kathleen's world . . . and threatens to irreversibly alter the destiny of humankind. For somewhere in the shadows, powerful unseen forces are watching . . . and waiting. Suddenly Kathleen is a target of covert government operatives as she races to uncover the mystery behind her parents' secret research and brutal deaths- a mystery locked in the human genome, in the sands of antiquity, and in the Book of Genesis. More than survival is at stake for Dr. Kathleen Sainsbury. The future of all humanity hangs in the balance . . . and the prize is the secret of life itself.
Brad Clifford's theory was just applied mathematics-but its implications were too hot for the frozen minds of his superiors. So they buried it--and him--under wraps of secrecy. Then Aubrey Philipsz, iconoclast and fellow genius, appeared on the scene to build the Genesis Machine Clifford's theory made possible. And all previous science and technology went into a tailspin. Suddenly, all weapons seemed useless before the previously unimagined power of the Genesis Machine. It could wreck a world or save it--and the men who ruled that world on a path of disaster now fought to gain control of this new force. But Clifford and Philipsz had another goal, another dream. They were reaching for the stars!
The history of Latin America told through vignettes, myths and legends.
The author compares what we know scientifically with ancient myths across time
Burton L. Visotzky, one of America's most respected scholars of religion, guides readers through a close reading of the narratives of the Book of Genesis, exposing their brutal power and revealing how their moral dilemmas apply to ethical issues we face in our lives today. Rabbi Visotzky has led highly regarded seminars, attended by novelists, poets, editors, filmmakers and critics, Fortune 500 CEOs, bankers, and attorneys. He also was a major participant in Bill Moyers' PBS Genesis series. His reading of Genesis opens the door to moral development for all readers--Christians, Jews, Muslims, and secularists. As Burton Visotzky says, the Book of Genesis seems to be, at least on first reading, "an ugly little soap opera about a dysfunctional family . . . a story about rape, incest, murder, deception, brute force, sex, and blood lust. But these stories reveal much about human dilemmas and ethical problems that mirror our own lives. By delving into the lives of Abraham, Sarah, Isaac, and Esau and holding up these characters of Scripture to the light of critical inquiry, Burton Visotzky reveals much that is fresh and useful about ethics and morality. "He is a rabbi who is earthy, playful, and full of insight, who refuses to draw a veil over the dark side of the Bible or of our own contemporary experience. " --Thomas Cahill, author of How the Irish Saved Civilization "[Visotzky] has a wonderfully earthy, human touch to his commentary, a perspective that can be especially refreshing for Christians who have seen the 'Old Testament' sanitized or ignored by their own tradition. " --San Francisco Chronicle "Thrilling original insights . . . a new way to see and feel these old, old sentences. " --The New York Times Magazine "Visotzky delights in turning the gem of each story so that its facets, especially the darkest ones, gleam out at us. . . . The Genesis of Ethics is a unique contribution to Bible discussion. . . . One can only applaud and thank him. " --Naomi Rosen, Congress Monthly
The Genesis of Justice: Ten Stories of Biblical Injustice that Led to the Ten Commandments and Modern Lawby Alan M. Dershowitz
From Gethesmane to the Grave: A commentary on the Passion Narratives in the Four Gospels
Symbolic thought is what makes us human. Claude Lévi-Strauss stated that we can never know the genesis of symbolic thought, but in this powerful new study Alan Barnard argues that we can. Continuing the line of analysis initiated in Social Anthropology and Human Origins (Cambridge University Press, 2011), Genesis of Symbolic Thought applies ideas from social anthropology, old and new, to understand some of the areas also being explored in fields as diverse as archaeology, linguistics, genetics and neuroscience. Barnard aims to answer questions including: when and why did language come into being? What was the earliest religion? And what form did social organization take before humanity dispersed from the African continent? Rejecting the notion of hunter-gatherers as 'primitive', Barnard hails the great sophistication of the complex means of their linguistic and symbolic expression and places the possible origin of symbolic thought at as early as 130,000 years ago.
This work is a personal account of the origins and early years of the Salk Institute for Biological Studies. Bourgeois crafts an engaging study that draws on her involvement with the Institute and on related archives, interviews, and informal conversations.The volume discusses the people who founded the Institute and built a home for renowned research--leading scientists of the time as well as non-scientists of stature in finance, politics, philanthropy, publishing, and the humanities. The events that brought people together, the historic backdrop in which they worked, their personalities, their courage and their visions, their clash of egos and their personal vanities are woven together in a rich, engaging narrative about the founding of a world-premier research institution.
First in the 4-book Genesis Wave saga.
Fourth in the Genesis Wave series. A Star Trek, the Next Generation novel.
Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of multiple myeloma. This book will give a comprehensive overview of the genetic and molecular epidemiology of multiple myeloma in order to get a more refined and conclusive understanding of this disease.
The first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists.
Genetic linkage maps are an increasingly important tool in both fundamental and applied research, enabling the study and deployment of genes that determine important biological traits. This concise introduction to genetic mapping in species with disomic inheritance enables life science graduate students and researchers to use mapping software to produce more reliable results. After a brief refresher on meiosis and genetic recombination, the steps in the map construction procedure are described, with explanations of the computations involved. The emphasis throughout is on the practical application of the methods described; detailed mathematical formulae are avoided and exercises are included to help readers consolidate their understanding. A chapter on recognising and solving problems provides valuable guidance for dealing with real-life situations. An extensive chapter dedicated to the more complex situation of outbreeding species offers a unique insight into the approach required for many economically important and model species, both plants and animals.
Conceived with the aim of sorting fact from fiction over genetically modified (GM) crops, this book brings together the knowledge of 30 specialists in the field of transgenic plants. It covers the generation and detection of these plants as well as the genetic traits conferred on transgenic plants. In addition, the book looks at a wide variety of crops, ornamental plants and tree species that are subject to genetic modifications, assessing the risks involved in genetic modification as well as the potential economic benefits of the technology in specific cases. The book's structure, with fully cross-referenced chapters, gives readers a quick access to specific topics, whether that is comprehensive data on particular species of ornamentals, or coverage of the socioeconomic implications of GM technology. With an increasing demand for bioenergy, and the necessary higher yields relying on wider genetic variation, this book supplies all the technical details required to move forward to a new era in agriculture.
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