- Table View
- List View
The pivotal role of mitochondrial functions in carcinogenesis is quite well established. However, the critical role of mitochondrial genome alterations to cancer development is muted in traditional textbooks. Recent scientific efforts have provided unequivocal evidence for mitochondrial genome mutations and content changes in cancer development, progression, and therapy. This pioneering book is a unique compilation of mitochondrial genome alterations in cancer. While primarily focused on the emerging role of mitochondrial genome changes, bioenergetics and signaling pathways, attention is also given to the metabolic transformations of the cancer cell, as well as the established altered cell death processes that underlie cancer evolution and treatment resistance.
Willie Mays's impossible over-the-head catch of Vic Wertz's bid for a game-winning home run in the 1954 World Series . . . Joe DiMaggio's effortless veto of Hank Greenberg's 450-foot shot at Yankee Stadium in 1939 . . . Joe Rudi's ninth-inning climb up the left-field wall at Cincinnati in the 1972 Series to rob Denis Menke of a game-winning triple . . . Brooks Robinson's diving, scrambling stops against Cincinnati in the 1970 World Series . . . Graig Nettles's defying gravity in the 1978 World Series as he robbed the Dodgers of at least five runs in game three . . . Sam Rice's swan dive into the Washington bleachers in 1925 to rob Earl Smith of a game-winning homer . . . There is almost nothing in baseball more exciting than a great fielding play-a climb up the outfield wall, a diving catch, an acrobatic stop, a clutch throw. Still, through most of the history of baseball, players and fans alike tended to be less than "enthusiastic about glove work. Frenchy Bordagaray, free spirit and sometime Brooklyn Dodger outfielder, was chasing a long fly ball one afternoon when his cap blew off. If you don't think priorities have shifted in the last half century, note that Frenchy first went back to retrieve his cap and then continued after the ball. When Jake Beckley, a left-handed first baseman, cocked his arm, turn-of-the-century fans sitting behind third base ducked. So did the fans behind first. Jack Chapman, one of the few outfielders in the mid-nineteenth century who could consistently catch fly balls, was hailed in sporting journals as "Death to Flying Things." Yes, fans screamed with delight whenever an outfielder succeeded in catching a high fly. Despite the claims of old-timers and their general criticism of today's super-athlete, the player of today is bigger, smarter, faster, stronger, better nourished, and better instructed than his counterpart of fifty years ago. The player of yesteryear would be blown away in today's high-powered game, and nowhere is the disparity more pronounced than in fielding and defensive strategy. A position-by-position look at the best and the worst, Mitts is a baseball fan's tribute to what has traditionally been the most neglected aspect of the game-defense. Rich in the lore of fielding gems, Mitts is a celebration of baseball's newest glamour figures-the men with the gold gloves.
Mitzvah Girls is the first book about bringing up Hasidic Jewish girls in North America, providing an in-depth look into a closed community. Ayala Fader examines language, gender, and the body from infancy to adulthood, showing how Hasidic girls in Brooklyn become women responsible for rearing the next generation of nonliberal Jewish believers. To uncover how girls learn the practices of Hasidic Judaism, Fader looks beyond the synagogue to everyday talk in the context of homes, classrooms, and city streets. Hasidic women complicate stereotypes of nonliberal religious women by collapsing distinctions between the religious and the secular. In this innovative book, Fader demonstrates that contemporary Hasidic femininity requires women and girls to engage with the secular world around them, protecting Hasidic men and boys who study the Torah. Even as Hasidic religious observance has become more stringent, Hasidic girls have unexpectedly become more fluent in secular modernity. They are fluent Yiddish speakers but switch to English as they grow older; they are increasingly modest but also fashionable; they read fiction and play games like those of mainstream American children but theirs have Orthodox Jewish messages; and they attend private Hasidic schools that freely adapt from North American public and parochial models. Investigating how Hasidic women and girls conceptualize the religious, the secular, and the modern, Mitzvah Girls offers exciting new insights into cultural production and change in nonliberal religious communities.
DJ's grandmother is a former fashion model who has restored an old mansion and turned it into a boarding house for rich teenaged girls who are interested in fashion, presenting DJ with a conflict between retaining her tomboy identity or changing her style, as she decides whether or not to try to fit in.
When Peter Hallock and Marie Cadant discover that their three-year-old sons were switched at birth, they agree that a marriage of convenience is best for everyone. But they didn't count on romance becoming part of the deal!
After the wedding of Diana Goode and Andrew Douglas, Diana teases that they will make a baby on their honeymoon. But long afterward, she is still not pregnant. As Diana and Andrew wait out each month only to be bitterly disappointed, they are forced to question just how much they are willing to go through to have a baby. Charlie Winwood dreams of a house filled with children. His bride, party-girl actress Barbie Mason, has other ideas. When he discovers he is sterile, Charlie has to rethink his deepest values -- and his marriage to a woman who shares none of his dreams.After ten years of living together, Pilar Graham, a prominent Santa Barbara attorney, marries Judge Brad Coleman, who is nineteen years her senior and father of two grown children. They are happy with their comfortable life together, à deux, until Pilar begins to wonder if she will someday regret not having a baby with Brad. Are they crazy to begin now -- with Brad about to become a grandfather and Pilar with a busy career, and in her early forties, possibly putting herself at risk?Through the lives of these couples, Danielle Steel shows us the mixed blessingswe face as we build our families and live our modern lives. She touches us with the triumphant people who prevail, their victories, their defeats, their tragedies and joys, their compromises, their lives.From the Paperback edition.
Frequent Cloth Paper Scissors contributors Debbi Crane and Cheryl Prater have whipped up this book featuring 20-plus smart and sassy projects divided like a cookbook into appetizers, main courses, and sweet treats for a fresh perspective on creating mixed-media projects. From artist books to assemblage, art quilts to art dolls, it's all here, plus how-to instructions on a variety of mixed-media, collage, and surface design techniques.Step-by-step projects are laid out like recipes complete with ingredients (materials), instructions (what to mix, add), and tips (how it should look, taste, etc.), showcasing colorful, innovative projects created with a variety of ephemera and mixed-media materials. Techniques for making art quilts, collages, assemblages, memory art, bookbinding, doll making, and paper crafting are included. An inspiring gallery of work by popular artists is also included.
Mixed Martial Arts (MMA) is a full-contact combat sport in which a variety of fighting techniques are used, including striking techniques (kicks, knees, and punches) and grappling techniques (clinch holds, submission holds, sweeps, takedowns, and throws). MMA is exploding in popularity. Packed with more than 300 full-color photographs, this book takes you through all the moves, step-by-step, demonstrating the various techniques required to master this martial arts phenomenon. It's an essential hand-book for anyone considering entering the ring.
Mixed media or mystery? There's a secret to understanding the mystery behind the hidden message in a work of mixed-media art. As Seth Apter knows, if you can get to know the artist, you will get to know the art. The Mixed Media Artist unlocks this mystery and provides an intimate look into the hearts, souls and creative processes of over 40 inspiring artists. Surprising self-portraits, innermost self-reflections and practical art-making tutorials are just some of the keys you'll find here to unlocking the door to a greater understanding of how and why art is made. Helpful how-tos: Throughout each section, artists share favorite tools, secret ingredients and step-by-step processes that go beyond the who to provide the how. 44 artists share creative perspectives and intimate thoughts: Provocative questions are answered not only in words, but multiple times as art, spotlighting the forces that make the art and the artists what and who they are. Compelling poll data: Answers collected from thousands of individuals reveal statistical insights on the creative community at large. Additional online content: Links to downloads, tutorials, videos and more are sprinkled throughout the book. Immerse yourself in the creative words and works of The Mixed Media Artist and get to know the artist behind your own art!
Imagine beautiful mosaic pieces with tiles that you easily create yourself! Mixed-Media Mosaics offers a fresh, new approach to a traditional art form. By making your own tiles from polymer clay, you control the size, shape, color and even the texture, resulting in beautiful finished pieces that include tabletops, boxes, jewelry and shrines. In addition to learning traditional tiling techniques such as working with grout and cutting glass tile, you'll also explore creative options for personalizing tiles: Discover the magic of mica powders and the regal look they can give to mosaics Learn quick and easy ways of adding paint to handcrafted and commercial tile See how easy it is to create molds and cast your own relief tiles Find ways to add personal meaning to your work with the addition of text tiles Experiment with the addition of beads, jewelry and other embellishments by embedding them right into the tile! Whether you'd like to complete a mosaic tabletop for your patio, a jewelry box as a special gift, or simply experiment with jewelry, you'll find the inspiration you seek in Mixed-Media Mosaics. Start creating your custom mosaic pieces today.
Mixed-Media Mosaics: Techniques and Projects Using Polymer Clay Tiles, Beads and Other Embellishmentsby Laurie Mika
Imagine beautiful mosaic pieces with tiles that you easily create yourself! Mixed-Media Mosaicsoffers a fresh, new approach to a traditional art form. By making your own tiles from polymer clay, you control the size, shape, color and even the texture, resulting in beautiful finished pieces that include tabletops, boxes, jewelry and shrines. In addition to learning traditional tiling techniques such as working with grout and cutting glass tile, you'll also explore creative options for personalizing tiles: Discover the magic of mica powders and the regal look they can give to mosaics Learn quick and easy ways of adding paint to handcrafted and commercial tile See how easy it is to create molds and cast your own relief tiles Find ways to add personal meaning to your work with the addition of text tiles Experiment with the addition of beads, jewelry and other embellishments by embedding them right into the tile! Whether you'd like to complete a mosaic tabletop for your patio, a jewelry box as a special gift, or simply experiment with jewelry, you'll find the inspiration you seek inMixed-Media Mosaics. Start creating your custom mosaic pieces today.
Play With Paint All Year Long!Incorporating paint into your mixed-media art has never been easier or more fun. Open up your paint box and delve into a year of creative ideas from 45 of your favorite artists. Whether you've used paint for years or have been anxious to try a new medium, you'll find great advice and ideas inside Mixed-Media Paint Box. Each week, you'll be guided with step-by-step instructions through a different project or technique that will add instant depth and drama to your art!Inside you'll find:52 projects and techniques, one for every week of the year, to inspire a weekly dose of creativity. Tips, hints and suggestions from some of your favorite authors, including Ruth Rae, Claudine Hellmuth, Chrissie Grace, Bernie Berlin and Margot Potter. Step-by-step instructions for jewelry-making, assemblage, journaling, collage and a variety of painting techniques to incorporate into your own art. Discover inspiration and new ways to express yourself every week inside Mixed-Media Paint Box!
What fun would it be if you had an identical twin. What fun could you get up to. Vickie who is four years old wishes for friends her age to play with. Then two boys, who look exactly alike go to live with their grandmother next door. Vickie and the twins Ronald and Donald, who she calls Onald when she can't tell them apart have a great time and the two is confused greatly by these two twins, but in the end Vickie learns to tell them apart.
DEATH AND A DAMSEL IN DISTRESS Strange things were happening to Lauren DiStefano. Since her brother's funeral, a mysterious driver had tried to run her down, menacing mobsters threatened her and a handsome FBI agent saved her life. Something was seriously wrong, and Lauren feared for her life. As Lauren discovered her brother Ric had left behind a trail of treachery, lies and mob ties, Special Agent David Latham seemed determined to uncover the truth. Could she place her trust, her life-and her heart-in David's hands?
Focusing on the relationship between two fiercely independent women--Teresa, a writer, and Alicia, an artist--this epistolary novel was written as a tribute to Julio Cortzar's Hopscotch and examines Latina forms of love, gender conflict, and female friendship. Ana Castillo's groundbreaking first novel, The Mixquiahuala Letters, received an American Book Award from the Before Columbus Foundation and is widely studied as a feminist text on the nature of self-conflict.
"It's a muddle, thought Monica. A muddle and I can't get it straight. I wish I knew what I should do. I wish I even knew what I want to do. . . I want to go on in the life that has somehow or other found me and claimed me. And I want so terribly to be happy. Oh god, don't let me slip under the surface of all the heavy-hearted dullness that seems to claim so many people. . . . "A Mixture of Frailties is so much more than the story of Monica Gall's life in London and her education as a singer. It is an account of her education as a human being, and the result is an absorbing novel, comic in the true sense, vivid and frequently moving.
The author has collected only folk songs, folk-tales and a few early poems and some contemporary poems, but has excluded Mizo short stories, novels, short plays, drama and essays.
Created through a "student-tested, faculty-approved" review process with direct input from students and faculty, *MKTG6* is an engaging and accessible solution to accommodate the diverse lifestyles of today's learners. *MKTG6* employs up-to-date, relevant examples from a wide range of independent upstarts and larger companies students love. *MKTG6* also offers a dynamic range of web-based review and testing products to facilitate today's on-the-go lifestyle.
The new edition of this successful and established textbook retains its two original intentions of explaining how to program in the ML language, and teaching the fundamentals of functional programming. The major change is the early and prominent coverage of modules, which the author extensively uses throughout. In addition, Paulson has totally rewritten the first chapter to make the book more accessible to students who have no experience of programming languages. The author describes the main features of new Standard Library for the revised version of ML, and gives many new examples, e.g. polynomial arithmetic and new ways of treating priority queues. Finally he has completely updated the references. Dr. Paulson has extensive practical experience of ML, and has stressed its use as a tool for software engineering; the book contains many useful pieces of code, which are freely available (via Internet) from the author. He shows how to use lists, trees, higher-order functions and infinite data structures. He includes many illustrative and practical examples, covering sorting, matrix operations, and polynomial arithmetic. He describes efficient functional implementations of arrays, queues, and priority queues. Larger examples include a general top-down parser, a lambda-calculus reducer and a theorem prover. A chapter is devoted to formal reasoning about functional programs. The combination of careful explanation and practical advice will ensure that this textbook continues to be the preferred text for many courses on ML for students at all levels.
MLA: The Easy Way! presents the basics of MLA style in a clear, concise, accurate, and easy-to-navigate package.
A complete, up-to-date guide for writing scholarly texts, documenting research sources, submitting manuscripts to publishers, and dealing with legal issues surrounding publication.
This is the story of the most honored photojournalist in media history. It contains a foreword by Bob Geldof. Amin's filming of the famine in Korem, in N. Ethiopia, was to inspire Bob Geldof and Live Aid.
A number one bestseller in Britain that topped the lists there for months, Stephen Fry's astonishingly frank, funny, wise memoir is the book that his fans everywhere have been waiting for. Since his PBS television debut in the Blackadder series, the American profile of this multitalented writer, actor and comedian has grown steadily, especially in the wake of his title role in the film Wilde, which earned him a Golden Globe nomination, and his supporting role in A Civil Action. Fry has already given readers a taste of his tumultuous adolescence in his autobiographical first novel,The Liar, and now he reveals the equally tumultuous life that inspired it. Sent to boarding school at the age of seven, he survived beatings, misery, love affairs, carnal violation, expulsion, attempted suicide, criminal conviction and imprisonment to emerge, at the age of eighteen, ready to start over in a world in which he had always felt a stranger. One of very few Cambridge University graduates to have been imprisoned prior to his freshman year, Fry is a brilliantly idiosyncratic character who continues to attract controversy, empathy and real devotion. This extraordinary and affecting book has "a tragic grandeur that lifts it to classic status," raved theFinancial Timesin one of the many ecstatic British reviews. Stephen Fry's autobiography, in turns funny, shocking, sad, bruisingly frank and always compulsively readable, could well become a classic gay coming-of-age memoir. From the Hardcover edition.
The average Mafia don knows more about effective leadership than a trunkful of Fortune 500 CEOs. For all the mob's well-deserved reputation for violence and immorality, its most successful members have always been remarkably astute businessmen. Former mobster Louis Ferrante reveals their surprisingly effective management techniques and explains how to apply them in any legitimate business. As an associate of the Gambino Family, Ferrante pulled off some of the biggest heists in U. S. history before the age of twenty-one, netting millions of dollars. His natural talent for management led bosses like John Gotti to rely on him. Now he offers time-tested Mafia wisdom, such as: * Three can keep a secret (if two are dead): Build trust with your colleagues. * You don't always need a gun to hit a target: Lead people without force. * It's never personal: When circumstances demand it, never hesitate to pull the trigger. Ferrante brings his real-life experience to the book, offering fascinating insights into Mafia behavior and sharing behind-the-scenes episodes almost as outrageous as those occurring on Wall Street every day. .