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Showing 88,301 through 88,325 of 146,254 results

Immune Infertility

by Rajesh K. Naz Walter K.H. Krause

This comprehensive overview of immune reactions inducing fertility disorders in both sexes first describes the nature and the function of sperm antigens which are capable to induce immune infertility as well as the methods to analyse and characterize these antigens. Secondly, the nature, the origin and induction of antisperm antibodies (ASA) in both sexes and the role of reproductive organs and their interaction with the immune system will be discussed. A large section of the book, which is most important for clinicians working in reproductive medicine, deals with the clinical impact of the immune reaction in reproductive medicine, including the methods of determination and the treatment in immune infertility. Closely related to immune infertility is the development of immune contraceptives which is also discussed.

The Immune System (3rd edition)

by Peter Parham

Parham (structural biology, microbiology, immunology, Stanford U.) offers a third edition to his textbook explaining the functions of the human immune system. It is specifically intended for undergraduate students in medical, dental, and pharmacy in immunology courses. Extensively updated, the textbook includes new chapters on innate and adaptive immunity, enhanced treatment of aspects of innate immunity such as the complement system and defensins, immunotherapies, and the nature of immune response in mucosal tissues and immunological memory. It is well-illustrated and includes essay, multiple choice, and case study questions at the conclusion of each chapter. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)

Immunity to Error through Misidentification

by Simon Prosser François Recanati

"Immunity to error through misidentification is recognised as an important feature of certain kinds of first-person judgments, as well as arguably being a feature of other indexical or demonstrative judgments. In this collection of newly commissioned essays, the contributors present a variety of approaches to it, engaging with historical and empirical aspects of the subject as well as contemporary philosophical work. It is the first collection of essays devoted exclusively to the topic and will be essential reading for anyone interested in philosophical work on the self, first-person thought or indexical thought more generally"--

Immunization Safety Review: Measles-mumps-rubella Vaccine And Autism

by Immunization Safety Review Committee

The National Academies Press (NAP)--publisher for the National Academies--publishes more than 200 books a year offering the most authoritative views, definitive information, and groundbreaking recommendations on a wide range of topics in science, engineering, and health. Our books are unique in that they are authored by the nation's leading experts in every scientific field.

Immunization Safety Review: Vaccinations And Sudden Unexpected Death In Infancy

by Immunization Safety Review Committee

With current recommendations calling for infants to receive multiple doses of vaccines during their first year of life and with sudden infant death syndrome (SIDS) the most frequent cause of death during the postneonatal period, it is important to respond to concerns that vaccination might play a role in sudden unexpected infant death. The committee reviewed epidemiologic evidence focusing on three outcomes: SIDS, all SUDI (sudden unexpected death in infancy), and neonatal death (infant death, whether sudden or not, during the first 4 weeks of life). Based on this review, the committee concluded that the evidence favors rejection of a causal relationship between some vaccines and SIDS; and that the evidence is inadequate to accept or reject a causal relationship between other vaccines and SIDS, SUDI, or neonatal death. The evidence regarding biological mechanisms is essentially theoretical, reflecting in large measure the lack of knowledge concerning the pathogenesis of SIDS.

Immunization Safety Review: Vaccines And Autism

by Institute of Medicine of the National Academies

This eighth and final report of the Immunization Safety Review Committee examines the hypothesis that vaccines, specifically the measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines, are causally associated with autism. The committee reviewed the extant published and unpublished epidemiological studies regarding causality and studies of potential biologic mechanisms by which these immunizations might cause autism. Immunization Safety Review: Vaccines and Autismfinds that the body of epidemiological evidence favors rejection of a causal relationship between thimerosal-containing vaccines and autism. The book further finds that potential biological mechanisms for vaccine-induced autism that have been generated to date are only theoretical. It recommends a public health response that fully supports an array of vaccine safety activities and recommends that available funding for autism research be channeled to the most promising areas. The book makes additional recommendations regarding surveillance and epidemiological research, clinical studies, and communication related to these vaccine safety concerns.

Immunogenetics

by Frank T. Christiansen Brian D. Tait

The HLA molecules are important regulators of the immune response through mediating antigen presentation and interaction between key immune mediating cells. They are also the major histocompatibility barriers to transplantation, which is the clinical paradigm of the self versus non self concept. It is now recognized that this diverse range of gene systems involved in the control of the immune response have been shown to be important in many aspects of clinical practice. As a result many new molecular and cellular methods have been developed for identifying these genes and their polymorphisms, and immunogenetic laboratories specializing in these methods have developed to support transplantation and other clinical programs. Immunogenetics: Methods and Applications in Clinical Practice focuses on methods for human clinical practice. The emphasis rests on those assays which are of established or potential clinical utility and are likely to be included in the repertoire of tests provided by a routine diagnostic and service laboratory. This volume also contains several review chapters of the MHC complex, the KIR complex, the human immunoglobulin allotypes, as well as reviews of the methods for the detection of alloreactive NK cells and the detection of HLA antibodies by solid phase assays. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Immunogenetics: Methods and Applications in Clinical Practice seeks to serve both the immunogenetics community and the wider scientific community with a collection of detailed information and helpful tips attained by many years of experience in the field.

Immunology of the Lymphatic System

by Laura Santambrogio

This book will be a comprehensive study of the lymphatic system and its immunological role. It will begin with lymphatic capillaries, their origin and development. It will treat lymph circulation, in general, with a special emphasis on lymph circulation in parenchymal organs. The next section will address lymph nodes, subcortical circulation and the conduit system. It will discuss organs with no lymphatic system, such as the brain. Finally, it will cover lymph composition and cells in the lymph. While primarily basic research, the volume will touch upon elements of the clinical, as well, broadening its scope and appeal.

Immunotoxicity, Immune Dysfunction, and Chronic Disease

by Rodney R. Dietert Robert W. Luebke

Chronic diseases are the leading cause of deaths worldwide and according to the World Economics Council and the Harvard School of Public Health, the cost of chronic diseases is expected to reach a staggering 48% of global gross domestic product by the year 2030. The urgency of the issue was demonstrated in 2011 when for only the second time in its existence, the U.N. General Assembly brought a health issue to the floor for consideration: chronic diseases. To date, most considerations of the issue have approached the topic from the vantage point that chronic diseases are a myriad of largely unconnected diseases and conditions arising in diverse tissues, organs and physiological systems. This book, Immunotoxicity, Immune Dysfuction, and Chronic Disease, deviates from that prior model. It considers the interconnectivity of chronic diseases with both environmental insult of the immune system and subsequent immune dysfunction and inflammatory dysregulation as the underlying basis for many, if not most, chronic diseases. This change in the perception of environment-immune linkages to chronic disease is significant and has immediate implications both for the prevention of disease as well as for the development of more effective therapeutic approaches. Rather than considering environmental factors and types of reported immune alterations (e.g., depressed humoral immunity) as is common in books involving immunotoxicity, the present book approaches the environment-immune-disease triad from the standpoint of the disease. Each chapter emphasizes one or more specific immune dysfunction-based chronic disease(s) or condition(s) (e.g., asthma, atherosclerosis, multiple sclerosis, lupus) and describes: 1) the suggested environmental risk factors, 2) the underlying immune dysfunction(s) associated with the disease and 3) the overall health consequences of the disease. This book is an early entry for a new Toxicology book series for Springer titled: Molecular and Integrative Toxicology (MaIT). The series will feature detailed research information, but in the context of a more integrative or holistic framework. As part of this framework, the chapters will contain a section on "Key Points" as well as "Recommendations" where appropriate. The goal is to cover the most timely, state-of-the-art issues in toxicology as well as to ensure that the information is maximally accessible for research scientists, teachers, physicians and students. We are particularly grateful to the numerous chapter authors for providing comprehensive and expert disease-oriented contributions. We are also appreciative of their willingness to consider their material not as disparate pieces of what has become a major health crisis, but rather as key pieces in a network of apparently interconnected health challenges.

Imogene's Antlers

by David Small

This a story of young Imogene who wakes up one morning to find she has sprouted antlers.

Imogene's Last Stand

by Nancy Carpenter Candace Fleming

Meet Imogene, a plucky heroine with a passion for history.As a baby, Imogene's first words were "Four score and seven years ago." In preschool, she fingerpainted a map of the Oregon Trail. So it's not surprising that when the mayor wants to tear down the long-neglected Liddleton Historical Society to make room for a shoelace factory, Imogene is desperate to convince the town how important its history is. But even though she rides through the streets in her Paul Revere costume shouting, "The bulldozers are coming, the bulldozers are coming!" the townspeople won't budge. What's a history-loving kid to do? Filled with quotes from history's biggest players--not to mention mini-bios on the endpapers--and lots of humor, here's the perfect book for budding historians.From the Hardcover edition.

iMovie '11 & iDVD: The Missing Manual

by David Pogue Aaron Miller

Apple's video-editing program is better than ever, but it still doesn't have a printed guide to help you get started. That's where this gorgeous, full-color book comes in. You get clear explanations of iMovie's impressive new features, like instant rendering, storyboarding, and one-step special effects. Experts David Pogue and Aaron Miller also give you a complete course in film editing and DVD design. Edit video like the pros. Import raw footage, add transitions, and use iMovie's newly restored, intuitive timeline editor. Create stunning trailers. Design Hollywood-style "Coming Attractions!" previews for your movies. Share your film. Distribute your movie in a variety of places--on smartphones, Apple TV, your own site, and with one-click exports to YouTube, Facebook, Vimeo, CNN iReport, and MobileMe. Make DVDs. Design the menus, titles, and layout for your DVDs, and burn them to disc.

iMovie 6 & iDVD: The Missing Manual

by David Pogue

While the last version of iMovie gave moviemakers the ability to capture and edit widescreen High Definition Video (HDV) from the new generation of camcorders, iMovie 6 is all about the ease of moviemaking itself. iMovie 6 includes five professionally designed themes with backgrounds, motion graphics, titles, and effects that act as building blocks for your projects. You can preview transitions and stunning new video effects--such as time-lapse video--in real time using the full screen. Or edit audio and add sound effects with a new built-in sound studio. For presenting your movie, Magic iDVD offers easy-to-use themes, including new widescreen options. Whether you're a professional or an amateur moviemaker, this is amazing stuff. But if you want to learn the full capabilities of these applications, Apple documentation won't make the cut. Instead, iMovie 6 & iDVD: The Missing Manual is the ideal third-party authority that covers all of these changes through an objective lens. This witty and entertaining guide from celebrated author David Pogue details every step of iMovie 6 and iDVD production. The book shows you how to: *Work on multiple iMovie projects at once and drag & drop clips among them *Output your creation to a blog, its own web page, or as a video podcast with iWeb *Use "Magic iMovie" to import your video and make a movie for you *Integrate with other iLife programs to use songs, photos, and an original soundtrack And a whole lot more. From choosing and using a digital camcorder to burning the finished work onto DVDs, posting it online, or downloading it to an iPod, iMovie 6 & iDVD: The Missing Manual zooms right in on the details in a clear, concise, and understandable manner. The book also provides a firm grounding in basic film technique so that the quality of your video won't rely entirely on magic.

iMovie HD & iDVD 5: The Missing Manual

by David Pogue

The latest versions of iMovie HD and iDVD 5 are, by far, the most robust moviemaking applications available to consumers today. But whether you're a professional or an amateur moviemaker eager to take advantage of the full capabilities of these applications, don't count on Apple documentation to make the cut. You need iMovie HD & iDVD 5: The Missing Manual , the objective authority on iMovie HD and iDVD 5. Even if you own a previous version of iMovie, the new feature-rich iMovie HD may well be impossible to resist. This video editing program now enables users to capture and edit widescreen High Definition Video (HDV) from the new generation of HDV camcorders, along with standard DV and the MPEG-4 video format. iMovie HD also includes "Magic iMovie" for making finished movies automatically. The feature does everything in one step--imports video into separate clips and adds titles, transitions, and music. The finished video is then ready for iDVD 5, which now includes 15 new themes with animated drop zones that can display video clips across DVD menus, just like the latest Hollywood DVDs. This witty and entertaining guide from celebrated author David Pogue not only details every step of iMovie HD video production--from choosing and using a digital camcorder to burning the finished work onto DVDs--but provides a firm grounding in basic film technique so that the quality of a video won't rely entirely on magic. iMovie HD & iDVD 5: The Missing Manual includes expert techniques and tricks for: *Capturing quality footage (including tips on composition, lighting, and even special-event filming) *Building your movie track, incorporating transitions and special effects, and adding narration, music, and sound *Working with picture files and QuickTime movies *Reaching your intended audience by exporting to tape, transferring iMovie to QuickTime, burning QuickTime-Movie CDs, and putting movies on the Web (and even on your cell phone!) *Using iDVD 5 to stylize and burn your DVD creation. iMovie HD & iDVD 5: The Missing Manual --it's your moviemaking-made-easy guide.

Imp

by Andrew Neiderman

Mary Oaks, a religious woman, marries a man who proves to be far less than she anticipated. After their first child, a daughter, is born, Mary retreats deeper into her religion and when her husband forces her to make love and she becomes pregnant, she decides this child must be evil. After her husband is killed in an DWI accident, she gives birth to the baby in the house and keeps it in the basement. Five years later, IMP finds his way out and becomes something of a terror during his nocturnal trips. When he endangers the life of a five year old girl, the horror is exposed.

The Imp That Ate My Homework

by Laurence Yep

Showdown in Chinatown! Jim wants to be a normal American kid. The only problem: His grandfather is the meanest, ugliest man in Chinatown. Grandpop has no patience for his "native born, no brains" grandson, and Jim is not all that interested in hearing about old Chinese customs and superstitions. But then a nasty green imp shows up, determined to settle an ancient family feud. The imp is making Jim's life miserable, and Grandpop seems to be the only one who can help. Could Grandpop really be the reincarnation of an ancient Chinese warrior-- the world's only hope against one mean green imp?

IMPACT Mathematics, Course 1

by Mcgraw-Hill Staff

IMPACT Mathematicsis designed for grades 6-8 with the goal of completing Algebra 1 content by the end of the 8th grade covering Pre-Algebra and Algebra 1 over 3 years. This program has been extensively field tested and has proven to be highly successful in a large urban district with an increase in assessment scores for all students in all three grade levels. IMPACT Mathematicsmakes the big ideas of mathematics accessible to middle school students through an emphasis on investigation, problem solving, mathematical understanding, and algebra skills. This edition boasts an improved visual design, updated content, and additional NSF-funded performance assessments. The goal ofIMPACT Mathematicsremains to help students develop a deep understanding of mathematics with an emphasis on algebra.

IMPACT Mathematics, Course 2

by Mcgraw-Hill Staff

IMPACT Mathematicsis designed for grades 6-8 with the goal of completing Algebra 1 content by the end of the 8th grade covering Pre-Algebra and Algebra 1 over 3 years. This program has been extensively field tested and has proven to be highly successful in a large urban district with an increase in assessment scores for all students in all three grade levels. IMPACT Mathematicsmakes the big ideas of mathematics accessible to middle school students through an emphasis on investigation, problem solving, mathematical understanding, and algebra skills. This edition boasts an improved visual design, updated content, and additional NSF-funded performance assessments. The goal ofIMPACT Mathematicsremains to help students develop a deep understanding of mathematics with an emphasis on algebra.

IMPACT Mathematics, Course 3

by Mcgraw-Hill Staff

IMPACT Mathematicsis designed for grades 6-8 with the goal of completing Algebra 1 content by the end of the 8th grade covering Pre-Algebra and Algebra 1 over 3 years. This program has been extensively field tested and has proven to be highly successful in a large urban district with an increase in assessment scores for all students in all three grade levels. IMPACT Mathematicsmakes the big ideas of mathematics accessible to middle school students through an emphasis on investigation, problem solving, mathematical understanding, and algebra skills. This edition boasts an improved visual design, updated content, and additional NSF-funded performance assessments. The goal ofIMPACT Mathematicsremains to help students develop a deep understanding of mathematics with an emphasis on algebra.

The Impact Of Electricity

by Tanja Winther

How does everyday life change when electricity becomes available to a group of people for the first time? Why do some groups tend to embrace this icon of development while other groups actively fight against it? This book examines the effects of electricity's arrival in an African, rural community. Based on ethnographic fieldwork in Zanzibar at different points in time, the author provides a compelling account of the social implications in question. The rhythm of life changes and life is speeding up. Sexuality and marriage patterns are affected. And a range of social relations, e.g. between generations and genders, as well as relations between human beings and spirits, become modified. Despite men and women's general appreciation of the new services electricity provides, new dilemmas emerge. By using electricity as a guide through the social landscape, the particularities of social and cultural life in this region emerge. Simultaneously, the book invites readers to understand the ways that electricity affects and becomes implicated in our everyday life.

The Impact of Genetically Engineered Crops on Farm Sustainability in the United States

by National Research Council of the National Academies

Since genetically engineered (GE) crops were introduced in 1996, their use in the United States has grown rapidly, accounting for 80-90 percent of soybean, corn, and cotton acreage in 2009. To date, crops with traits that provide resistance to some herbicides and to specific insect pests have benefited adopting farmers by reducing crop losses to insect damage, by increasing flexibility in time management, and by facilitating the use of more environmentally friendly pesticides and tillage practices. However, excessive reliance on a single technology combined with a lack of diverse farming practices could undermine the economic and environmental gains from these GE crops. Other challenges could hinder the application of the technology to a broader spectrum of crops and uses. Several reports from the National Research Council have addressed the effects of GE crops on the environment and on human health. However, The Impact of Genetically Engineered Crops on Farm Sustainability in the United States is the first comprehensive assessment of the environmental, economic, and social impacts of the GE-crop revolution on U.S. farms. It addresses how GE crops have affected U.S. farmers, both adopters and nonadopters of the technology, their incomes, agronomic practices, production decisions, environmental resources, and personal well-being. The book offers several new findings and four recommendations that could be useful to farmers, industry, science organizations, policy makers, and others in government agencies.

Impact of Government Expenditure on Growth: The Case of Azerbaijan

by Junko Koeda Vitali Kramarenko

A report from the International Monetary Fund.

The Impact of MacroEconomic Policies on Poverty and Income Distribution

by François Bourguignon Maurizio Bussolo Luiz A. Pereira da Silva

A companion to the bestseller, The Impact of Economic Policies on Poverty and Income Distribution, this title deals with theoretical challenges and cutting-edge macro-micro linkage models. The authors compare the predictive and analytical power of various macro-micro linkage techniques using the traditional RHG approach as a benchmark to evaluate standard policies, such as a typical stabilization package and a typical structural reform policy.

Impact of Nonlinearities on Fiber Optic Communications

by Shiva Kumar

This book covers the recent progress in fiber-optic communication systems with a main focus on the impact of fiber nonlinearities on the system performance. Over the past few years, there has been significant progress in coherent communication systems mainly because of the advances in digital signal processing techniques. This has led to renewed interest in fiber linear and nonlinear impairments and techniques to mitigate them in electrical domain. In this book, the reader will find all the important topics of fiber optic communication systems in one place with in-depth coverage by the experts of each subtopics. Pioneers from each of the sub-topics have been invited to contribute. Each chapter will have a section on fundamentals, review of literature survey and the recent developments. The reader will benefit from this approach since many of the conference proceedings and journal articles mainly focus on the authors' research work without spending space on preliminaries.

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