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Protected by the dark of night, Jaimie Piper runs. But is anywhere safe when Evil is hunting you? She's just a twelve year-old girl, bumped around between foster homes and relegated to school classes for challenged kids, those lagging in their test scores or with behavioral issues. But her real problem is that she can sense something the other kids can't--something dark. Something compelling her to run for her life. All Crockett Grey wants is to mark the anniversary of his daughter's death alone. But when his student Jaimie comes to him, terrified, her need for protection collides with his grief, and a tangled web of bizarre events sends them both spiraling toward destruction. Crockett's one hope of getting his life back is to uncover the mysterious secrets of Jaimie's past and her strange gift. It isn't long before his discoveries lead him to a darker conspiracy, secrets guarded by the highest seat of power in the world--the Vatican.From the Trade Paperback edition.
"A huge treat for mystery fans." --Peggy EhrhartYou can't tiptoe when murder's afoot...It's Bastille Day in Paris. The Happy Hoofers--Tina, Janice, Pat, Mary Louise, and Gini--are all set to kick off the fete by dancing the cancan on a beautiful sightseeing cruise down the Seine. As the leggy ladies soak in the magic of the city of lights, everything is magnifique...until a very important patron goes belly-up on the top deck. On the heels of their French debut, murder takes center stage. The five daring dancers will need to step lively to stop the crafty killer fast...or their grand finale will turn out far more explosive than the fireworks over the Eiffel Tower...Includes Fashion Tips And Tasty Recipes
Fletcher Wyant and his wife Jane had been married for fifteen years. They had built the perfect marriage - two wonderful kids, a warm beautiful home, and their own private never-ending love affair. Fletcher thought he knew Jane completely. No dark secrets. No hidden past. Then one hot summer week everything changed. And suddenly, brutally, Jane became a cold stranger.
A heartfelt tale of one woman's journey to discover the secrets of her mother's hidden past and confront her own uncertain future, this compelling, emotionally resonant novel about the frustrations of blood ties will appeal to fans of Emily Giffin and Jennifer Weiner.On the surface, Olivia has it all: a high-powered career, a loving family, and a handsome fiancé. She even seems to be coming to terms with her mother Jane's premature death from cancer. But when Jane's final wish is revealed, Olivia and her elder sister, Georgia, are mystified. Their mother rarely spoke of her rural Southern hometown, and never went back to visit--so why does she want them to return to Huntley, Georgia, to scatter her ashes?Jane's request offers Olivia a temporary escape from the reality she's long been denying: she hates her "dream" job, and she's not really sure she wants to marry her groom-to-be. With her fourteen-year-old niece, Logan, riding shotgun, she heads south on a summer road trip looking for answers about her mother.As Olivia gets to know the town's inhabitants, she begins to peel back the secrets of her mother's early life--truths that force her to question her own future. But when Olivia is confronted with a tragedy and finds an opportunity to right a terrible wrong, will it give her the courage to accept her mother's past--and say yes to her own desire to start over?
National Review has always published letters from readers. In 1965 the magazine decided that certain letters merited different treatment, and William F. Buckley, the editor, began a column called "Notes & Asides” in which he personally replied to the most notable and outrageous correspondence. Culled from four decades of the column, Cancel Your Own Goddam Subscription includes exchanges with such well-known figures as Ronald Reagan, Richard Nixon, John Kenneth Galbraith, A. M. Rosenthal, Auberon Waugh, Arthur Schlesinger Jr. , and many others. There are also hilarious exchanges with ordinary readers, as well as letters from Buckley to various organizations and government agencies. Combative, brilliant, and uproariously funny, Cancel Your Own Goddam Subscription represents Buckley at his mischievous best.
National Review has always published letters from readers. In 1965 the magazine decided that certain letters merited different treatment, and William F. Buckley, the editor, began a column called "Notes & Asides" in which he personally replied to the most notable and outrageous correspondence.Culled from four decades of the column, Cancel Your Own Goddam Subscription includes exchanges with such well-known figures as Ronald Reagan, Richard Nixon, John Kenneth Galbraith, A.M. Rosenthal, Auberon Waugh, Arthur Schlesinger Jr., and many others. There are also hilarious exchanges with ordinary readers, as well as letters from Buckley to various organizations and government agencies.Combative, brilliant, and uproariously funny, Cancel Your Own Goddam Subscription represents Buckley at his mischievous best.
Evan Tanner ran head-first into a piece of shrapnel in Korea, and now he can't sleep. Ever. Which can be an asset for a dedicated linguist, term paper forger, thief, lost cause enthusiast . . . Spy. Tanner takes on jobs for a covert intelligence organization so secret that even those who work for it have no idea who they're working for. Now his nameless supervisor wants him to sneak behind the Iron Curtain, storm an impregnable castle in Prague (alone!), and rescue an old Slovak who's got a pressing date with a hangman's noose. The trouble is the prisoner is an unrepentant Nazi who makes Goering look like Mister Rogers. Tanner hates Nazis. If he's caught (which is likely) the U.S. will deny that they know him. And Tanner will be executed. After being tortured, no doubt. All in all, there are many excellent reasons why Tanner should refuse this assignment. So, naturally, he says yes.
Cancer is the second biggest killer in the world, but few of us understand how it works or how it is treated. In this illuminating introduction, Paul Scotting explains the science behind the disease and explores why some of us are more likely to develop it than others. Arguing that we're in a new age of understanding that will revolutionize the fight againtst cancer, Scotting maps out the promising future strategies for its prevention, treatment, and cure.
50 strategies to employ in the fight against cancer
This definitive guide, revised and updated with over 25% new material, empowers cancer patients and their loved ones to move beyond their disease. Greg Anderson, a cancer survivor, has designed this book for the recently diagnosed, those with recurring symptoms, and those who are well but have a lingering fear that the disease may strike again. Informative and inspiring, Cancer: 50 Essential Things to Do goes hand-in-hand with the patient's medical treatment and is an invaluable roadmap to recovery. Filled with practical, healing "action steps" that have been used by thousands of cancer survivors, the revised edition also contains important new information--including recently approved medical treatment options, updated cancer research, and Internet resources--geared toward making sense of the fast-changing world of cancer treatment and recovery. .
'This book creates new ground for all health professionals working in cancer care to read, enjoy, look at and question their practice.' Caroline Adcock, Clinical Practice Educator - Haematology and Oncology, Royal Shrewsbury Hospital Cancer and Cancer Care is a complete study of cancer, the care of people with the disease and its impact on everyday life. Addressing the physical and psychosocial aspects of the illness in detail, it covers all fundamental aspects of cancer diagnosis, treatment, survival and aspects of psychosocial support for all those affected by cancer: patients, their families, and their healthcare providers. Chapters include: - A review of the latest theory and evidence on over 30 separate topic areas - Reflective questions which challenge readers to reappraise what they have learned - Chapter overviews and chapter summaries which highlight the key points The book is essential reading for all those on cancer care courses at undergraduate and postgraduate level. It will be valuable reading for nurses, oncologists, psychologists, social workers and all healthcare practitioners and researchers working with people affected by cancer.
Cancer and Vitamin C: A Discussion of the Nature, Causes, Prevention, and Treatment of Cancer with Special Reference to the Value of Vitamin Cby Ewan Cameron Linus Pauling
This book weighs the value and limitations of various modes of treatment: surgery, radiation, chemotherapy, hormones, immunotherapy, and a number of unorthodox therapies, including Laetrile.
The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
personal experience with the stratigies used to beat cancer when the doctors had given up on the case.
Since its publication, A Cancer Battle Plan has sold more than 200,000 copies and continues to be a source of inspiration and information for people struggling with cancer and other degenerative diseases. Now, Dave Frahm offers a companion book of practical help and guidance for those who want to build a natural program to lighten their toxic load, better their health, and find a healthy, safe way to fight chronic disease. In A Cancer Battle Plan Workbook readers will start to regain control of their health and learn how to: * identify the stressors impacting health; * detoxify the body; * restore the body's natural healing power and protective system; * assess how the body is performing and what help it needs; and * develop six key characteristics of people who have won back their health. With A Cancer Battle Plan Workbook, readers can begin to win the war against cancer. .
"Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer. "
Cancer care today often provides state-of-the-science biomedical treatment, but fails to address the psychological and social (psychosocial) problems associated with the illness. This failure can compromise the effectiveness of health care and thereby adversely affect the health of cancer patients. Psychological and social problems created or exacerbated by cancer--including depression and other emotional problems; lack of information or skills needed to manage the illness; lack of transportation or other resources; and disruptions in work, school, and family life--cause additional suffering, weaken adherence to prescribed treatments, and threaten patients' return to health. Today, it is not possible to deliver high-quality cancer care without using existing approaches, tools, and resources to address patients' psychosocial health needs. All patients with cancer and their families should expect and receive cancer care that ensures the provision of appropriate psychosocial health services. Cancer Care for the Whole Patient recommends actions that oncology providers, health policy makers, educators, health insurers, health planners, researchers and research sponsors, and consumer advocates should undertake to ensure that this standard is met.
This is a rare compilation of clinically focused chapters on the practice of oncology in more than 25 countries and areas around the world that experience ongoing or intensifying ethnic, religious, and nationalistic conflict. Each chapter is written by an internationally respected local physician or nurse. Topics include the relationship between local culture and the local practice of mainstream modern medicine, critical clinical issues faced by local physicians, and options for when and how to incorporate palliative care. The book ends with chapters on the United States' current initiatives on promoting cancer care training in these regions, and another on clinical concepts for Western clinicians undertaking oncology practice in emerging countries. The audience includes oncologists around the world: those practicing medicine in similarly extreme circumstances; Western oncologists organizing or preparing for medical missions; and Western oncologists who wish to learn from the experiences of oncologists who practice under radically different conditions.
Despite advances in detection and treatment, cancer remains a source of pain and distress to patients and of complex challenges to the loved ones caring for them. The trend toward shorter hospital stays in particular has increased the physical, psychological, and financial burden on caregivers, often leading to adverse effects on patients. Cancer Caregiving in the United States illuminates these complex concerns with authoritative detail. This wide-ranging volume provides a comprehensive survey of cancer-related issues, including those affecting the care triad (patients-family members- professionals) and quality of care as well as the numerous physical, emotional, and financial challenges that caregivers may need to confront. Sources of caregiver difficulty at each stage of the disease, from diagnosis to end of life, are explored. Each chapter analyzes its topic in terms of practice, research, education, and policy, providing a wealth of literature reviews, assessment and care models, interventions, and recommendations for future study and practice. Coverage includes: Caregiving issues for cancer patients with long-term, short-term, and intermittent needs.Family caregivers as members of the treatment team.The impact of health disparities on caregivers.Cancer care policy and advocacy.End-of-life issues for cancer caregivers.Legal, financial, and ethical issues. Cancer Caregiving in the United States is a core reference for researchers, professionals/scientist-practitioners, and graduate students in such caregiving fields as clinical psychology, social work, nursing, public health and medicine, social policy, and educational policy.
Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer. Opening with a section on targeting cancer cell metabolism as an anticancer strategy, this detailed volume continues with parts describing protocols to study epigenetic control of cancer, protocols to study cancer metastasis, as well as two new techniques for cancer study Written for the highly successful Methods in Molecular Biology series, chapters include introductions for their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Second Edition is an ideal guide to the techniques that will aid researchers in exploiting our current knowledge in order to make a profound impact in cancer prevention and treatment.
This volume presents state of the art of methods that can be useful for both basic and translational researchers to conduct chemoprevention preclinical studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Chemoprevention: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. Throughout the past few years, the cancer chemopreventive potencies and treatment effects of a number of natural dietary agents present in different food sources have been evaluated by various experiments. Some of them have progressed to early clinical trials. This volume is a specialized book presenting the research evidence relevant to the use of specific diet therapy in cancer chemoprevention and treatment. We begin with lessons learned from dietary resveratrol as an effective agent with anticancer properties against malignancies, followed examples of flavonoids from fruits and vegetables in the prevention and treatment of cancer. Evidence for the beneficial influence of diet enriched with flax seed oil and green tea on cancer will be reviewed. Soy food intake may enhance the effects on anticancer treatment for breast cancer, whereas lycopene-rich foods may possess chemopreventive efficacy. There are also discussions on the contribution of the cancer preventive effects of the antioxidant-rich foods and Mediterranean diet. In addition, the modulation of proteasome pathways by nutraceuticals is highlighted. Finally, we close the book with a discussion on the attenuation of cell survival signaling by bioactive phytochemicals in the prevention and therapy cancer.
A simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience. The first part of this book is unique in explaining the recent developments in the field in terms of their point of action in the natural history of cancer. The second and third sections contain a more straightforward description of practical aspects of chemotherapy, and the current place of drug treatment in everyday cancer management, including the outcomes of that treatment.
When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way--an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease. Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don't know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses--rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science's comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body. Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.
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