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Infertility in Early Modern England
by Daphna Oren-MagidorThis book explores the experiences of people who struggled with fertility problems in sixteenth and seventeenth-century England. Motherhood was central to early modern women's identity and was even seen as their path to salvation. To a lesser extent, fatherhood played an important role in constructing proper masculinity. When childbearing failed this was seen not only as a medical problem but as a personal emotional crisis. Infertility in Early Modern England highlights the experiences of early modern infertile couples: their desire for children, the social stigmas they faced, and the ways that social structures and religious beliefs gave meaning to infertility. It also describes the methods of treating fertility problems, from home-remedies to water cures. Offering a multi-faceted view, the book demonstrates the centrality of religion to every aspect of early modern infertility, from understanding to treatment. It also highlights the ways in which infertility unsettled the social order by placing into question the gendered categories of femininity and masculinity.
Infertility in Women with Polycystic Ovary Syndrome
by Stefano PalombaThis book presents up-to-date knowledge on infertility in the context of polycystic ovary syndrome (PCOS) and provides clear evidence-based guidance on its treatment. The book opens by discussing anovulation, oocyte quality, and the endometrium in women with PCOS, infertility and subfertility cofactors, and the impact of PCOS phenotypes on fertility. All aspects of management are then thoroughly addressed. The available medical treatments for PCOS-related infertility - including antiestrogens, aromatase inhibitors, insulin-sensitizing drugs, and gonadotropins - are reviewed, and other potential therapeutic approaches, such as acupuncture and laparoscopic ovarian drilling, are assessed. Careful attention is also devoted to the role of lifestyle interventions. The use of controlled ovarian stimulation in infertile PCOS patients undergoing intrauterine insemination or in vitro fertilization is examined in detail, as are the benefits of in vitro maturation of oocytes. This book will be of value to all who are involved in the care of women with PCOS and related infertility issues.
Inflammation: From Molecular and Cellular Mechanisms to the Clinic
by Jean-Marc Cavaillon Mervyn SingerThe leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.
Inflammation
by Björn E. Clausen Jon D. LamanThis volume presents a broad selection of cutting-edge methods and tools that will enable the reader to investigate the multi-faceted manifestations of inflammation. Inflammation: Methods and Protocols is divided into four sections: the first three sections describe protocols investigating immune-mediated inflammatory disease models affecting barrier organs to the environment; the skin, the lung, and the intestinal and oral mucosa. The fourth section illustrates inflammatory disease models of the brain, joints, and vasculature. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and practical, Inflammation: Methods and Protocols aims to inspire the experienced investigator and the young experimenter alike to disentangle the fascinating process of inflammation.
Inflammation, Aging and Cancer
by Mahin KhatamiThis book was prepared as extension of author's accidental discoveries on experimental models of acute and chronic ocular inflammatory diseases that were established at the University of Pennsylvania in 1980's. Analyses of original data suggest a series of first evidence for direct link between inflammation and developmental phases of immune dysfunction in multistep tumorigenesis and angiogenesis. The only evidence presented on initial events for interactions and synergies between activated host and recruiting cells toward tumorigenesis. Effective immunity was defined as balance between two highly regulated and biologically opposing arms, Yin and Yang of acute inflammation, an amazingly precise signal communications between immune and non-immune systems requiring differential bioenergetics. Unresolved inflammation is a common denominator mapping aging process and induction of 'mild', 'moderate' or 'severe' immune disorders including cancers. Our knowledge of the fascinating biology of immunity in health or chronic diseases is fragmentary, chaotic and confusing, particularly for cancer science. Lack of progress in curing majority of chronic diseases or cancer is primarily due to the fact that scientists work on isolated molecules/cells or topics that are funded and promoted by decision makers in medical/cancer establishment. Despite existence of over 25 million articles on cancer-related topics, cancer biology and cure remain mysteries to be solved. After a century of cancer research, the failure rates of therapies for solid tumors are 90% (+/-5). Current reductionist views on cancer science are irresponsible, shut-gun approaches and create chaos. Outcomes are loss of millions of precious lives and economic drain to society. Very little is known about initial events that disturb effective immunity whose function is to monitor and arrest growth of cancerous cells or defend against other external or internal hazardous agents that threaten body's survival. The author demonstrates the serious need for systematic understanding of how immune disruptors and aging process would alter effective immunity. Outcomes of proposed orderly studies are expected to provide logical foundations for cost-effective strategies to promote immunity toward a healthier society. The policy makers and medical/cancer establishment are urged to return to the common sense that our Forefathers used to serve the public.
Inflammatory Bowel Diseases: A Clinician's Guide
by Ashwin N. Ananthakrishnan Daniel K. Podolsky Ramnik J. XavierInflammatory Bowel Diseases: A Clinician’s Guide provides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician as a concise and practical resource for day to day use. Written by the experts, Inflammatory Bowel Diseases: A Clinician’s Guide is an essential tool for all gastroenterologists managing patients with inflammatory bowel disease.
Inflammatory Dermatopathology
by Steven D. Billings Jenny CottonThis fully updated and revised new edition will guide the reader to develop a systematic approach to the diagnosis of inflammatory disorders of the skin. It covers the most common and clinically important inflammatory disorders of the skin in a image-rich easy to read format. Each section includes a practical tips section to help navigate the differential diagnosis. Examples of diagnostic comments are provided that practicing pathologists can utilize in their own reports. Therefore, this book will not only guide the reader in how to approach inflammatory dermatoses, it will also help with writing the report. All chapters are revised and updated and include new images. The second edition of Inflammatory Dermatopathology will be of great value to surgical pathologists, pathology residents, dermatology residents, and dermatopathology fellows.
Influenza and Respiratory Care
by Mieczyslaw PokorskiRespiratory infections constitute a major public health concern. The goal of this book is to share knowledge on the best advances in influenza and influenza-like viral infections, and new molecular-based diagnostic methods that discern the antigenic shift providing viruses the ability to constantly evolve and elude the host immune response. Co-infections, co-morbidities, persistently meager anti-flu vaccination coverage, and infection complications are dealt with. The chapters also further insight into such topics as the effect of sex hormones, and socioeconomic and anthropometric measures, on respiratory and immune functions underlying the severity of asthma and respiratory allergy. Psychological functioning in respiratory disorders, taking into account quality of life, illness acceptance, and depressive symptoms is also reviewed as it is all too often underestimated by healthcare providers. The book is intended for clinicians, researchers, students, and all other actors in health-related issues.
Informal Payments and Regulations in China's Healthcare System
by Jingqing YangThis text addresses the key issue of informal payments, or 'red packets', in the Chinese Healthcare system. It considers how transactions take place at the clinical level as well as their regulation. Analysing the practice from the perspectives of institutions and power structure, it examines how institutional changes in the pre-reform and reform era have changed the power structure between medical professions, patients and the Party-state, and how these changes have given rise and perpetuate the practice. Drawing from qualitative data from interviews of medical professionals, the author recognises the medical profession as a major player in the health care system and presents their perception of the practice as the taker of 'red packets' and their interactions with the patient and the state surrounding the illegal practice in an authoritarian power structure. The books considers the institutional reasons that motivate doctors to take, patients to give, and the government to "tolerate" red packets, arguing that the bureaucratization of the medical profession, society of acquaintances and shortage of quality of medical services jointly create an institutional setting that has given rise to these informal payments. Contributing to a rounded understanding of the problems of healthcare reform in China, this book is a key read for all scholars interested in the issue of informal payments and healthcare politics in transition economies.
Informatics for Health Professionals (Navigate 2 Advantage Access)
by Kathleen Mastrian Dee McGonigleNew edition available December 2019! Informatics for Health Professionals is an excellent resource to provide healthcare students and professionals with the foundational knowledge to integrate informatics principles into practice. <P><P>The theoretical underpinning of this text is the Foundation of Knowledge model, which explains how informatics relates to knowledge acquisition, knowledge processing, knowledge generation, knowledge dissemination, and feedback. Once readers understand informatics and the way in which it supports practice, education, administration, and research, they can apply these principles to improve patient care at all levels.
Information Infrastructures within European Health Care
by Margunn Aanestad Miria Grisot Ole Hanseth Polyxeni VassilakopoulouThis book is open access under a CC BY-NC 2. 5 license. The book aims to be a resource for those interested in planning and implementing large-scale information infrastructures for novel electronic services in health care. The focus of this book is on the pivotal role of the installed base (i. e. the already existing elements of an infrastructure) for ensuing infrastructural development. The book presents rich empirical cases on the design, development and implementation of core infrastructural components (e-prescription and public patient-oriented web platforms) in different national settings across Europe. Therefore, this is a book in which theoretical insights and practical experiences are tightly connected. Contributions have been sourced from a network of academics that have been working on the topic for years, and who have previously collaborated and shared a common understanding of the challenges entailed in expanding information infrastructures within healthcare. The book aims to become a reference for those seeking theoretical and empirical insights for conceptualizing and steering the evolution of information infrastructures in healthcare. The two types of systems (e-prescription and public patient-oriented web platforms) have been selected because they are widespread across Europe, because they invite comparisons, and because they are exemplary of two different types of aims. E-prescription initiatives are usually seen as opportunities to improve healthcare delivery by systematic and not dramatic change. Public patient-oriented web platforms are seen as opportunities to pursue wider and more radical innovation. This book targets researchers, practitioners and students who would benefit from a book providing a comprehensive view to contemporary approaches for the design and deployment of large-scale, inter-organizational systems within healthcare. This book is open access under a CC BY 4. 0 license.
Information Processing in Medical Imaging: 25th International Conference, IPMI 2017, Boone, NC, USA, June 25-30, 2017, Proceedings (Lecture Notes in Computer Science #10265)
by Marc Niethammer, Martin Styner, Stephen Aylward, Hongtu Zhu, Ipek Oguz, Pew-Thian Yap and Dinggang ShenThis book constitutes the proceedings of the 25th International Conference on Information Processing in Medical Imaging, IPMI 2017, held at the Appalachian State University, Boon, NC, USA, in June 2017. The 53 full papers presented in this volume were carefully reviewed and selected from 147 submissions. They were organized in topical sections named: analysis on manifolds; shape analysis; disease diagnosis/progression; brain networks an connectivity; diffusion imaging; quantitative imaging; imaging genomics; image registration; segmentation; general image analysis.
Information Technology in Medical Diagnostics
by Waldemar Wójcik & Andrzej SmolarzFor many centuries, people have tried to learn about the state of their health. Initially, in the pre-technological period, they had to rely only on their senses. Then there were simple tools to help the human senses. The discovery of X-rays, which allowed people to look “inside” the body, turned out to be a major breakthrough. Contemporary medical diagnostics is increasingly being assisted by information technology that allows, for example, thorough image tissue analysis or pathology differentiation. They also allow very early preventive diagnostics. Influenced by information technology, “classic” diagnostic techniques change and new ones arise. Information Technology in Medical Diagnostics presents selected and extended conference papers from Polish, Ukrainian and Kazakh scientists. They address problems of the application of new methods of image processing for analysis of medical images, new methods of classification of medical data as well as new medical imaging methods. Some of the presented technologies are inspired by the functioning of living organisms. Information Technology in Medical Diagnostics is of interest not only to academics and engineers, but also to professionals involved in biomedical engineering, and seeking for solutions for issues that cannot be solved with the help of “traditional” technologies.
Informatorium voor Voeding en Diëtetiek
by Majorie Former Gerdie Van Asseldonk Jacqueline Drenth Caroelien SchuurmanHet Informatorium voor voeding en diëtetiek is een systematisch naslagwerk met alles wat men moet weten op het gebied van voeding en diëtetiek. Dit standaardwerk voor iedere diëtist is online toegankelijk gemaakt via een geavanceerd zoeksysteem, waardoor men altijd snel en efficiënt antwoorden op vragen vindt over voeding en diëtetiek.
Informatorium voor Voeding en Diëtetiek
by Majorie Former Gerdie Van Asseldonk Jacqueline Drenth Caroelien SchuurmanHet Informatorium voor voeding en diëtetiek is een systematisch naslagwerk met alles wat men moet weten op het gebied van voeding en diëtetiek. Dit standaardwerk voor iedere diëtist is online toegankelijk gemaakt via een geavanceerd zoeksysteem, waardoor men altijd snel en efficiënt antwoorden op vragen vindt over voeding en diëtetiek.
The Informed Patient: A Complete Guide to a Hospital Stay (The Culture and Politics of Health Care Work)
by Karen A. Friedman Sara L. MerwinEven the most capable individuals are challenged when confronted with the complexity of the modern hospital experience. The Informed Patient is a guide and a workbook, divided into topical, focused sections with step-by-step instructions, insights, and tips to illustrate what patients and their families can expect during a hospital stay. Anyone who will experience a hospital stay—or friends or family who may be in charge of a patient’s care—will find all the help and advice they could need in the detailed sections that cover every aspect of what they can expect.Karen A. Friedman, MD, and Sara L. Merwin, MPH, offer hands-on advice about how patients, health care providers, and medical staff can work together to achieve good outcomes. Through anecdotes, tips, sidebars, and clinical scenario vignettes, The Informed Patient presents ways to enhance and optimize a hospital stay, from practical advice on obtaining the best care to dealing with the emotional experience of being in the hospital.
Inguinal Hernia Surgery
by Giampiero CampanelliThis book, which describes in detail the most common procedures employed in inguinal hernia surgery, is exceptional in reflecting fully the most recent advances, as well as the most established techniques, in knowledge and practice. The role of recently developed and emerging technologies, including robotics, minimally invasive surgery, and biological meshes, is clearly explained, highlighting useful tips and tricks. The descriptions of traditional procedures, such as the Lichtenstein repair, are brought fully up to date and take into account the novel perceptions that professionals have of them, for example regarding the important role of nurses. The reader will also find guidance on established and new treatments for specific pain conditions, including postoperative chronic pain, the pubic inguinal pain syndrome, and obscure groin pain in women. The need for such an update on inguinal hernia surgery became clear at the 1st World Conference on Abdominal Wall Hernia Surgery, which highlighted the huge differences in the approaches adopted by scientists around the world and was chaired by the editor of this book. Inguinal Hernia Surgery will be a useful tool for all health care practitioners involved in hernia surgery.
The Inheritance: A Family on the Front Lines of the Battle Against Alzheimer's Disease
by Niki KapsambelisAn inspiring race against time: The courageous, hopeful story of the one family who may hold the key to finding a cure for Alzheimer’s disease.Every sixty-nine seconds, someone is diagnosed with Alzheimer’s disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer’s, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer’s research and offers the brightest hope for future treatments—and possibly a cure. Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer’s through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. Their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this incredible narrative redefines courage in the face of one of the most pervasive and mysterious pandemics of our time.
Inherited Neurological Disorders
by Zhi-Ying WuThis book provides up-to-date information on various inherited neurological disorders, presenting 40 cases of inherited neurological disorders with genetic diagnosis and/or pathological confirming. These disorders include cerebellar ataxia (SCA1, SCA2, SCA3, etc. ), epileptic attacks related disorders (MELAS, MERRF, TSC, etc. ), motor neuron related disorders (ALS, HSP, CMT, etc. ), movement disorders (PD, PKD, DRD, etc. ), ion channel diseases (hypokalemic periodic paralysis, normal potassium periodic paralysis), muscle diseases (DMD, FSHD, LSM, etc. ), and dementia and psychiatric disorders (HD, CADASIL, CARASIL, etc. ). With the format of case study, one type of diseases is discussed on each chapter, basically consisted of 5 sections. Section 1 focuses on the detailed clinical features, physical examination and hematological examination, while Section 2 addresses questions regarding diagnosis and differential diagnosis. Additional information such as imaging material and genetic/pathological results are provided in Section 3, followed by the final diagnosis in Section 4. Section 5 presents a systemic review for each specific disease. The book will benefit clinicians especially neurologists, medical students, researchers and healthcare professionals facing difficult cases, particularly those involving fundamental research and diagnostic methods.
Injuries and Health Problems in Football
by C. Niek van Dijk Philippe Neyret Moises Cohen Stefano Della Villa Helder Pereira J. Miguel OliveiraThis book offers a comprehensive overview of current knowledge on the health problems and injuries associated with football and their clinical management. After an opening section on technical aspects and fundamental principles, all areas of football traumatology are addressed. The coverage includes muscle, tendon, and stress injuries of the lower limbs and injuries to the ankle and foot, knee, hip and groin, spine and head, and upper limbs. An individual section is also devoted to the most significant heart and other health conditions that may be encountered in players of all ages and standards. Follow-up, rehabilitation, and return to activity are discussed, and the role of performance enhancement strategies is carefully examined, with description of nutritional guidelines and the evidence on use of dietary supplements. A concluding section highlights the potential of the next generation of biologics to improve the regeneration and biofunctionality of damaged tissues. This book is written by world-renowned experts and has been produced in cooperation with ISAKOS. It will serve as a reference in the field of orthopaedics.
Inleiding in de psychopathologie
by Ron Van DethDit boek is primair geschreven voor zorgprofessionals (in opleiding) die op zoek zijn naar een handzaam en verantwoord overzicht van de psychische stoornissen, zoals die in de DSM-5 worden onderscheiden. Behalve de verschijningsvorm, krijgen oorzaken en behandeling ruim aandacht. Ieder hoofdstuk schetst een breed klinisch beeld van de verschillende stoornissen en gaat systematisch in op de volgende aspecten: Kenmerken: affectieve, somatische, gedrags- en cognitieve symptomenDiagnose: veelgebruikte vragenlijsten, differentiële diagnostiek en beslisbomenPrevalentie: life-timeprevalentie en jaarprevalentie Etiologie: biologisch, psychologisch en psychosociaal perspectiefBehandeling: biologische, psychologische en psychosociale aanpakPrognose: het beloop van de stoornis. Naast de DSM-5 is dit boek gebaseerd op klinisch-psychologische en psychiatrische handboeken uit binnen- en buitenland. Met het oog op de praktijk komen in elk hoofdstuk ook Nederlandse richtlijnen en protocollen aan bod. Daarmee hebben (aankomend) klinisch- en GZ-psychologen, huisartsen, POH-GGZ, psychotherapeuten, psychiaters en andere behandelaars in de zorg de meest recente èn relevante kennis van psychische stoornissen binnen handbereik.
Innate Antiviral Immunity: Methods and Protocols (Methods in Molecular Biology #1656)
by Karen MossmanThis book explores methods to study the complex and evolving interplay between a virus and its host that range from model systems to the detection of chemical molecules. The collection starts with the application of humanized mice and zebrafish as model organisms to study virus-host interactions and induction of innate immune responses. Subsequent chapters outline diverse methods to detect small interfering RNAs, microRNAs, and virus-derived dsRNA from a variety of cells, tissues, and organisms, as well as to interrogating the cytosolic RNA and DNA sensing pathways, including using RNA PAMPs as molecular tools, purification of cGAMP from virus particles and infected cells, and mechanisms to visualize the subcellular localization and activation of the adaptor proteins MAVS and STING. Cutting-edge methods, including high-throughput and genome-wide CRISPR/Cas9 screens, chromosome conformation capture, and whole-exome sequencing, are described to identify novel mediators, pathways, and variants underlying host susceptibility. Given the importance of studying these pathways and players under physiologic conditions, methods describing the isolation of primary mouse sensory neurons and group 2 innate lymphoid cells are also provided. Finally, this collection comes full circle back to the whole organism level and concludes with epidemiological methods to investigate virus-host interactions and the induction of innate immunity. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Innate Antiviral Immunity: Methods and Protocols spans a diverse array of approaches to study and elucidate the intricacies of this vital area of study.
Innovation of Diagnosis and Treatment for Pancreatic Cancer
by Hiroki YamaueThis collection of chapters describes in detail the latest insights into the evaluation of resectability and neoadjuvant therapy to pancreaticoduodenectomy and distal pancreatectomy for pancreatic cancer. Shedding light on immunotherapy and gene therapy, this volume comprehensively covers treatments and procedures for the disease, allowing surgeons and trainees to gain an overview and explore innovative treatments. It also provides information on various cases using tools such as endoscopic ultrasound, MDCT, PET for diagnosis and laparoscopy and robotic resection methods. Edited and authored by pioneering professionals, Diagnosis and Treatment for Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, surgical oncologist and general surgeons interested in treatment of pancreatic cancer care.
Innovations in Biomedical Engineering
by Marek Gzik Ewaryst Tkacz Zbigniew Paszenda Ewa PiętkaThis book presents the proceedings of the "Innovations in Biomedical Engineering IBE'2016" Conference held on October 16-18, 2016 in Poland, discussing recent research on innovations in biomedical engineering. The past decade has seen the dynamic development of more and more sophisticated technologies, including biotechnologies, and more general technologies applied in the area of life sciences. As such the book covers the broadest possible spectrum of subjects related to biomedical engineering innovations. Divided into four parts, it presents state-of-the-art achievements in: * engineering of biomaterials, * modelling and simulations in biomechanics, * informatics in medicine * signal analysis The book helps bridge the gap between technological and methodological engineering achievements on the one hand and clinical requirements in the three major areas diagnosis, therapy and rehabilitation on the other.
Inpatient Dermatology: Caring For Dermatologic Issues In Hospitalized Patients
by Laura A. Taylor Robert G. Micheletti Karolyn A. Wanat Misha Rosenbach Inpatient Dermatology is a concise and portable resource that synthesizes the most essential material to help physicians with recognition, differential diagnosis, work-up, and treatment of dermatologic issues in the hospitalized patient. Complete with hundreds of clinical and pathologic images, this volume is both an inpatient dermatology atlas and a practical guide to day-one, initial work-up, and management plan for common and rare skin diseases that occur in the inpatient setting. Each chapter is a bulleted, easy-to-read reference that focuses on one specific inpatient dermatologic condition, with carefully curated clinical photographs and corresponding histopathologic images to aid readers in developing clinical-pathologic correlation for the dermatologic diseases encountered in the hospital. Before each subsection the editors share diagnostic pearls, explaining their approach to these challenging conditions. This book is structured to be useful to physicians, residents, and medical students. It spans dermatology, emergency medicine, internal medicine, infectious disease, and rheumatology. Inpatient Dermatology is the go-to guide for hospital-based skin diseases, making even the most complex inpatient dermatologic issues approachable and understandable for any clinician.