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Hip Arthroplasty: Current and Future Directions
by Mrinal SharmaThis book brings together the latest updates and current trends in arthroplasty of the hip covering the basics as well as complex and revision surgery. Eminent arthroplasty surgeons across the globe have contributed to the chapters and shared their clinical experiences. There are separate sections on primary hip arthroplasty, complex scenarios requiring hip replacement, and detailed management of related complications. It covers revision hip replacement in detail with the latest updates on surgical techniques and implants. There are separate sections on computer navigation and robotic-assisted hip replacement surgeries. A special section on implants and tribology has been added. The language of the book is easy-to-read, user friendly with pictorial representation of relevant surgical steps. Case-based discussions, surgical tips, and summary has been added in each chapter. The references given at the end of each chapter would be useful for those doing research. This book is an essential on-the-desk book for practicing orthopedic surgeons across the globe, beginners in arthroplasty surgery, postgraduate students of orthopedics, DNB students, and those interested in research.
Reliability Engineering Technology of Digital Diagnosis and Treatment Equipment
by Xiuqing Li Jun Gao Wen LiThis book focuses on the reliability engineering of medical devices, especially digital diagnosis and treatment equipment in China. It details the professional technologies and application methods of reliability design analysis, fault model analysis and reliability test of digital diagnosis and treatment equipment, to meet the needs of project undertakers of digital diagnosis and treatment equipment. From the three aspects: safety analysis and EMC design protection, material selection and control, and software engineering and quality, this book provides professional and technical ideas and methods of reliability for the quality problems prone to occur in the field of medical devices, as well as method guidance for readers. Meanwhile, it runs through the whole process of design, engineering, testing, production and management of all digital diagnosis and treatment equipment research and development enterprises and even product R & D enterprises in the field of medicaldevices. It is used as reading materials for personnel of testing institutions and evaluation institutions in medical devices.
Family Medicine OSCE: First Aid to Objective Structured Clinical Examination
by Shaima Lari Shammah Al Memari Dana Al MarzooqiIn this book, a clinician can experience the most typical medical subjects in a primary care setting, which is the highlight. The book brings knowledge and counseling skills into action as it takes you through various scenarios. In addition, it serves as a guide for passing the Objective Structured Clinical Examination, or "OSCE," by mirroring the Middle East and Arab World exam format in a structured fashion. With that, the book left behind distinctive traces that productively revealed its value and reputation.The book chapters provide a systematic approach to patient-centered medical problems, making it easier and handier for the students. The process covers in-depth history remarks, an organized set of physical examinations, and careful counseling tips.
Breast Oncoplasty and Reconstruction: Principles and Practice
by S. V. S. DeoThe book covers the concepts, techniques and strategies of oncoplastic breast surgery and reconstruction for breast cancer patients. It includes contemporary surgical procedures with step-by-step illustrations, pre-operative and post-operative considerations, pearls and pitfalls shared from the personal experiences and surgical practices of the individual authors. Experienced authors with diverse backgrounds and an in-depth understanding of the domains are involved in curating the content of the book. This book mainly focuses on practical tips and surgical techniques to reach a broad spectrum of surgeons practicing breast surgery from low and middle-income countries. It provides both the scientific basis and practical tips from experienced surgeons in the field. Breast cancer is an emerging major public health problem in low and middle-income countries. While the surgical approach to breast cancer has witnessed a major shift from mastectomy to breast conservation, oncoplasty and reconstruction in western countries, the field of breast surgery is still evolving in low and middle-income countries. Barriers to adopting newer surgical approaches include socio-cultural factors, disease-related factors, resource-related factors and availability of expertise. This book fills the gap and helps surgeons in low and middle-income countries in adapting contemporary breast surgical techniques into their day-to-day practice. This book will be relevant for surgical oncologists, breast and endocrine surgeons, general surgeons practicing breast surgery and plastic surgeons. Additionally, it will serve as a resource book for residents and fellows from general surgery, surgical oncology, breast surgery and plastic surgery streams.
Rights in Practice for People with a Learning Disability: Stories of Citizenship
by Liz Tilly Jan WalmsleyThis book aims to raise awareness about the possibility of achieving the goals of the United Nations Convention on the Rights of Persons with Disabilities (UNCRPD), in order for all disabled people to enjoy the benefit of human rights. The stories of people who have been supported to enjoy their rights and their citizenship will enable readers to focus on how services and support can enable people with a learning disability to have their rights upheld, with an outcome of citizenship, independence and achievement. Despite the UNCRDP being in place since 2006, a significant number of learning disability service provider organisations and professionals in the UK are not aware of its existence. This book aims to bridge the gap between policy and practice to demonstrate the value of a human rights approach as the foundation for services and support for people with a learning disability.
Synbiotics in Human Health: Biology to Drug Delivery
by Kamal DuaThis reference book discusses the role of synbiotics in a wide range of disease states, including cardiovascular, reproductive, metabolic, neurodegenerative, gastrointestinal, thrombotic, skin, and inflammatory disorders. It reviews the functions of probiotics in the diagnosis, prevention, or treatment of various disease states. The book further covers improving the targeting efficiency of synbiotics through advanced drug delivery systems such as nanoparticles, microparticles, liposomes, microemulsion, solid lipid nanoparticles, and nano lipid carriers. The chapter addresses the implications of oral and topical delivery of synbiotics in different diseases and presents the safety assessment of synbiotics and clinical trials associated with synbiotics containing drug delivery systems for the treatment of diseases. The book also explores the synergistic welfare of synbiotics nutraceuticals in various conditions such as chronic respiratory diseases, gut health, and neurological functions and examines the toxicological profile, and regulatory aspects of nutraceutical supplements. As such, this book is a valuable resource for academics, research and industry professionals working in Pharmaceutical Sciences, Food Biotechnology, Immunology, and Health Sciences.
Case-based Atlas of Cardiac Imaging
by Sanjiv SharmaThis case-based atlas encompasses all aspects of imaging in congenital cardiac defects, cardiac masses, inflammatory and acquired heart diseases, cardiomyopathies and coronary-related pathologies. The chapters begin with a description of the imaging approach, followed by cases comprehensively covering the gamut of clinical scenarios that may be encountered in clinical practice. The atlas provides pertinent information about each discussed disease state, its imaging diagnosis and recent advances, including role of radiology in management, follow up and prognostication. Cases that may pose as imaging differentials accompany the index case, followed by a variety of companion cases illustrating the possible spectrum of abnormalities that the reader may be confronted with while dealing with the index case. It acts as a guide for the cardiovascular radiologist, physician, paediatrician, internist, cardiologist, cardiothoracic surgeon as well as radiology residents for inculcating an evidence-based approach for choosing the right imaging algorithm in the given clinical situation. The highly visual design of the atlas enables it to act as a quick and ready reference.
Diagnosis of Mycobacterium
by Amit Singh Divakar SharmaThis book covers all the aspects related to the laboratory diagnosis of Mycobacterium. Laboratory diagnosis includes microscopic to advance molecular diagnosis. Moreover, it deals with the methods used to detect antimycobacterial susceptibility tests and drug resistance. Chapters cover most potential methods and techniques from traditional to advanced future diagnostics for identifying tuberculosis, NTM, and latent TB infections. Also discussed the challenges and opportunities in the diagnostic science of infectious disease. This book offers assistance to students, postgraduate medical students, researchers, medical practitioners, postdoctoral fellows, microbiologists, nurses, and public health officers working in tuberculosis control programs to understand various modalities for diagnosis and drug-resistance tuberculosis.
Skeletal Dysplasias & Congenital Malformations
by Surender Singh YadavThis book presents significant clinical and radiological descriptions with photographic details of common and rare Skeletal Dysplasias and Congenital Malformations. It simplifies and classifies skeletal dysplasias and other orthopedic congenital anomalies with the help of a collection of complex cases.It contains 1195 images (404 Coloured). It also explains the simple and systematic approach to correct diagnosis and adequate management of such patients. All types of congenital anomalies of the musculoskeletal system are included, some of them treated.This book assists PG students in the Department of Orthopaedics, Paediatrics, and Radiology. It is also helpful as a ‘Reference Book’ for the concerned Medical teachers, Researchers, General Practitioners, and all others interested. The book will also benefit the parents of such children for correct diagnosis and required management.
Eel Science (Fisheries Science Series)
by Katsumi Tsukamoto Mari Kuroki Soichi WatanabeThis book is a compilation of eel research and fish migration studies for more than 40 years showing the research history and recent advances in eel studies. Dr. Katsumi Tsukamoto, the esteemed editor of this book, has been actively involved in eel research as one of the leading scientists in the world for a long time, and he and his team successfully collected the fertilized eggs and spawn-condition adult eels from the wild for the first time in the world. This book compiles the essentials of the scientific findings obtained by the editor and his colleagues and reviews the latest references of eel science. Knowledge and information in the book such as a spawning area survey, research on artificial production of glass eels, the discovery of a new species, etc. will attract the reader’s interest, as these are written based on the authors’ experiences. Readers can obtain a comprehensive understanding of eels from various aspects of eel science including the cultural and socio-economic importance of eels and valuable scientific information using state-of-the-art approaches. The book also endeavors to contribute to the conservation of eel species, some of which have been classified as endangered by the IUCN and to promoting harmonious coexistence between humans and nature.
Fungi Bioactive Metabolites: Integration of Pharmaceutical Applications
by Sunil Kumar Deshmukh Jacqueline Aparecida Takahashi Sanjai SaxenaThis book presents the exploration and exploitation of various bioactive metabolites obtained from fungi isolated from diverse habitats for pharmaceutical applications. Various fungal sources have been brought under one umbrella ranging from endophytes, marine fungi, endolichenic fungi to fungi existing in the extremophilic conditions like desert and Antarctica and Artic environment. The book tries to cover maximally the range of the pharmaceutical applications wherein these bioactive agents from fungi have been exploited or are in the clinical pipelines and primarily include antibacterial, antifungal, antibiofilm, anticancer, antioxidant, autoimmunological, anti-inflammatory, and anti-thrombotic diseases. The book further emphasizes on the novel strategies to screen or enhance secondary metabolite production. Some other topics includes peptides, nonpeptides drugs, pigments, and enhancement of production of Echinocandin and Kojic acid. The role of bioinformatics in drug discovery and biotransformations have also been discussed. This book is going to be a comprehensive treatise and a valuable source for mycologists, biotechnologists, microbiologists, biotechnologists, and undertaking research in pharmaceutical sector as well as academia in setting up their research aspirations for using fungi in the process of drug discovery and development.
Modern Taxonomy of Bacteria and Archaea: New Methods, Technology and Advances
by Wen-Jun Li Jian-Yu Jiao Nimaichand Salam Manik Prabhu Narsing RaoThis book introduces the current approaches in prokaryotic taxonomy and streamlines the advanced techniques for use in prokaryotic systematics. While highlighting the key differences in the taxonomy of cultured and not-yet-cultured bacteria and archaea, it presents the genomic technology involved in microbial systematics that serves as comprehensive guidelines for isolating and identifying bacteria. Microbial systematics is a fundamentally important discipline area for microbiologists and those seeking to understand Earth’s biodiversity. As bacterial taxonomy is critical in microbial ecology and clinical microbiology works, the correct identification of microbes is crucial. However, the microbial collection existing and described as cultured species so far are either based on the taxonomic pattern that existed during its time of first cultivation. With evolving technology, many microbes were found to be wrongly classified. Therefore, it is essential to keep in contact withthe developing technology and methods for the correct placement of cultured bacteria and their identification. This book is an excellent guideline for adequately identifying, classifying, and describing novel taxa of bacteria and archaea.
Atlas of Basic Liver Histology for Practicing Clinicians and Pathologists
by K. S. Mouleeswaran Joy Varghese Mettu Srinivas ReddyThe book provides a visual run-through of liver pathology through high-quality images from the healthy liver through acute liver injury to chronic liver disease - stressing on common mechanisms for specific histological appearances, correlating them with clinical features and laboratory investigations to reach the diagnosis. Individual chapters in this richly illustrated atlas cover the wide gamut of liver disease, including types of liver injury, viral hepatitis, fatty liver disease and its complications, vascular and autoimmune liver diseases, pediatric liver diseases, liver tumors, and finally, pathology of the transplanted liver.This book bridges the gap by integrating basic clinical information with histopathological findings, as existing books cater primarily to the pathologist’s needs and do not provide sufficient clinical background to engage the clinician. It serves as a quick guide for adult and pediatric hepatologists, liver surgery doctors, pathologists as well as trainees in gastroenterology, hepatology, gastrointestinal surgery, liver transplantation and pediatric gastroenterology.
The Ageing Population: Impact Analysis on 'Societal and Healthcare Cost'
by Polly LamaAging is an irreversible natural process; we as humans develop many age-related disadvantages impacting many aspects of our life. Aging is not a negative process, but the ever-increasing band of the aging population creates a different socioeconomic and healthcare cost-associated risk that may hinder the sustainable development goals of any country and the world in general. Thus, the primary purpose of this book is to cover all aspects of the aging population. Each chapter in this book will give its readers a comprehensive understanding of how an aging population affects public programs such as pension plans, social welfare aids, healthcare costs, asset loss, and labor income, including chapters focusing on the demographic distribution of age-related diseases and injuries that increase healthcare cost, current social psychological reforms, and scientific research work adopted continent wise towards sustaining the aging population. Therefore, this book is helpful for students, teachers, and practitioners studying/working in the broad areas of social sciences, economics, and scientific research advancements in aging. This book serves as a bridge toward planning and developing new policies and practices.
Functionalized Smart Nanomaterials for Point-of-Care Testing (Smart Nanomaterials Technology)
by Amit Kumar Mandal Suvankar Ghorai Azamal HusenThis book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing ‘smart’ nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen. The POCT refers to medical diagnostic tests performed near the place and time of patient care. During the recent pandemic of COVID-19, many realized the importance of affordable, rapid and accurate POCT devices and their usefulness to combat the spread of the infection. The chapters in this book describe the emergence of ‘smart’ nanomaterials with unique physical and chemical properties being utilized in POCT devices for immobilizing biorecognition elements and labels for signal generation, transduction and amplification. It showcases the applications of these smart nanomaterials and their superiority in developing point-of-care diagnostics devices in a wide range of applied fields like food industry, agriculture sector, water quality assessment, pharmaceuticals and tissue engineering. It also looks into the challenges associated and future direction of research in this promising field. This book caters as reference book for researches from the field of nanobiotechnology and biomedical sciences who are interested in the development of rapid, affordable and accurate POCT devices.
Surgical Treatment of Chronic Constrictive Pericarditis
by Ujjwal K. Chowdhury Lakshmi Kumari SankhyanThis book provides comprehensive information and clarity on all aspects of diagnosing and managing constrictive pericarditis. The operative procedures for constrictive pericarditis are presented in detail with technical tips supplemented by surgical videos. Further, it explores and guides on issues with mixed opinions like the role of corticosteroids, timing of the operation, choice of the operative procedure, terminologies to describe the extent of decortication, and the requirement of cardiopulmonary bypass. Despite experience spanning over 100 years, there is no fool-proof formula in the published literature that can be used in selecting an optimal surgical approach for a given patient. The terms "radical", "total", "extensive", "complete", "subtotal", "adequate", "near-total" and "partial" pericardiectomy also have been variably used in the literature, often without a precise definition of the limits of pericardial resection.Providing an update on the latest advancements and long-term results of pericardiectomy appeals to all clinicians managing constrictive pericarditis. For the trainees, it offers insights into surgical techniques' relevant anatomy and foundation. The book will be beneficial to MBBS, MD, MS, M.Ch (CTVS), DM (Cardiology), Diplomate of National Board (Cardiology and CTVS), FRCS, FRACS, MD (USA, Canada, and in all developing and developed countries).
Pharmacological Interventions for Osteoporosis (Tissue Repair and Reconstruction)
by Andy H. Choi Sian Yik LimThis book provides readers a fundamental insight into the basic properties of the pharmaceutical agents used in the treatment of osteoporosis. It provides insight into mechanisms of action, updated information on clinical utility, and possible side effects associated with the use of these pharmaceutical agents. In particular, it highlights the use of two monoclonal antibodies romosozumab and denosumab in activating osteoblast differentiation and inhibiting osteoclasts. It also discusses two anabolic pharmaceutical agents, teriparatide and abaloparatide to treat osteoporosis. They have been shown to reduce the incidence of non-vertebral and vertebral fractures significantly after they were administered to patients daily as subcutaneous injections. The content of this book caters to researchers, scientists, and clinical practitioners who are interested in the treatment of osteoporosis using pharmaceutical agents.
Artificial Intelligence in Anesthesiology
by Ming Xia Hong JiangConsidering the rapid developments in digital and information technologies, artificial intelligence has long been a hot topic in medicine. This book discusses applications of artificial intelligence in anaesthesiology, including control of anesthesia, risk prediction, ultrasound guidance, pain management, and operating room logistics. This book first defines basic concepts of AI, and give a brief overview of a few algorithms frequently used in AI and machine learning. A review of current AI and machine learning applications for the prediction of anesthesia conditions is also discussed, including those for the prediction of difficult airways before surgery, of adverse events and sedation effects during surgery, and of vomiting and pain after surgery. Even without extensive promotion and clinical application, AI is in development in anesthesiology; furthermore, it has a great deal of potential to maintain further development in the future. Lastly, ethical and safety considerations are discussed alongside AI limitations and challenges in anesthesiology.
Healthcare Policy, Innovation and Digitalization: Contemporary Strategy and Approaches (Accounting, Finance, Sustainability, Governance & Fraud: Theory and Application)
by Eyüp Çetin Hilal ÖzenThis book takes a deep look at healthcare in today’s post-pandemic world. It combines both theory and application to reflect a new era for healthcare. The need for innovation, digitalization, and enhanced policies in healthcare has never been greater than it is today. Taking this need into consideration, this book offers a multidisciplinary approach to healthcare, in both managerial and clinical views. Since the book combines both qualitative and quantitative studies about healthcare, readers will receive a broad view of healthcare issues and policies in today’s world.
Advanced Functional Materials for Optical and Hazardous Sensing: Synthesis and Applications (Progress in Optical Science and Photonics #27)
by Rakesh Kumar Sonker Kedar Singh Rajendra SonkawadeThis book highlights the significance and usefulness of nanomaterials for the development of sensing devices and their real-life applications. The book also addresses various means of synthesizing functional materials, e.g., hydrothermal deposition process, electrospinning, Ostwald ripening, sputtering heterogeneous deposition, liquid-phase preparation, the vapor deposition approach, and aerosol flame synthesis. It presents an informative overview of the role of functional materials in the development of advanced sensor devices at the nanoscale and discusses the applications of functional materials in different forms prepared by diverse techniques in the field of optoelectronics and biomedical devices. Major features, such as type of advanced functional, fabrication methods, applications, tasks, benefits and restrictions, and saleable features, are presented in this book. Advanced functional materials for sensing have much wider applications and have an enormous impact on our environment.
Natural Product-based Synthetic Drug Molecules in Alzheimer's Disease: Therapeutic & Theranostic Agents
by Abha Sharma Gyan Prakash ModiThis book illustrates the importance of natural products as the source for the development of novel drugs for the treatment of neurodegenerative disorders, including Alzheimer's disease. It also highlights the role of reactive oxygen species and altered metal homeostasis in the progression of Alzheimer’s disease and examines the potential of antioxidants and anti-chelating agents in the clinical intervention of neurodegenerative diseases. The book also discusses the role of neuroinflammation in the pathogenesis of Alzheimer’s disease. The chapters provide information about the drug targets, progress in the development of natural product-based therapeutics, biomarkers, fluorescent diagnostic tools, and theranostic for Alzheimer's disease. The book also provides information about the design and synthesis of natural product-based derivatives against the various targets of Alzheimer's disease including epigenetic targets and the metal dyshomeostasis hypothesis. Cutting across different disciplines, this book is a valuable source for neuroscientists, chemical biologists, pharmaceutical researchers, and synthetic biologists.
Tools and Techniques in Radiation Biophysics
by Ashima PathakThis textbook describes the study of radiation, covering the basic concepts and their advanced applications, and highlights the handling of radioisotopes and radiation measurements using various instruments. The book also focuses on the effects and up-to-date applications of radiation on biological systems and their use in diagnosing and treating various diseases. Chapters provide an easy understanding of the subject matter with the help of self-explanatory, well-illustrated figures and easy-to-grasp language. “Tools and Techniques in Radiation Biophysics” is designed for undergraduate and post-graduate studying radiation Biophysics as one of the major courses in medical physics, nuclear medicine, biophysics, and other applied sciences. The multi-disciplinary approach of this book facilitates learning and a deep understanding of the concepts and helps the readers develop an interest in the subject so that they can pursue their careers efficiently in this field. Researchers and lecturers will value this book to enhance their knowledge and clarify queries.
Integrated Nanomaterials and their Applications
by Deepa Suhag Atul Thakur Preeti ThakurThe book provides an overview of different nanoparticles, their classification, and their applications in healthcare, food sciences, environmental sciences, and agricultural sciences. The introductory chapters discuss different types of nanoparticles, their types, and their structural properties. The subsequent chapter examines factors that influence the biocompatibility and toxicity of NPs for the safe and sustainable development of emerging nanoparticles. The chapter systematically reviews the nanoparticle-based contrast agents employed in most common biomedical imaging modalities. The book further examines the applications of advanced nanoparticle design that are utilized for both non-personalized and precision applications for improving precision therapies. The book provides a comprehensive update on nanoparticles’ toxic effects, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. This book is an ideal guide for researchers and students interested in understanding the applications of nanoparticles in biomedical sciences and the healthcare sector.
Atlas of Head Neck and Skull-base Surgery
by Nitin M Nagarkar Rupa Mehta Ambesh Singh Karthik N Rao Prajwal S DangeHead and neck anatomy is fairly constant, meticulous dissection of the structures and forms the backbone of a successful surgery. The entire diverse spectrum of head neck cancers, thyroid lesions, neural, lymphangiomatous lesions, and carotid body tumors are discussed along with preop, intraop, and postop follow-up pictures. The painstaking selection of intraoperative photographs of various patients operated at our center with an aim to demonstrate the finesse of the surgical management is the motive behind this atlas. The reader picking up this beautifully illustrated volume draws on the surgical expertise of an impressively well-trained surgical team. The atlas will be a pleasure to read and a powerful force to grab the advance treatment standards in the huge variety of head and neck disorders. This atlas will be a valuable resource to aspiring head and neck surgeons and oncologists, and it will act as a volume to refer to in the surgical management of head and neck disorders.
Disability Practice: Safeguarding Quality Service Delivery
by Christine Bigby Alan HoughThis open access book critically engages with the social, political and ethical implications of support for people with disability to be fully included in society. The authors examine contemporary issues of quality and safeguarding in disability services, translating research and practice wisdom into foundational knowledge. Written by leading researchers, the book provides a comprehensive overview of knowledge and practice necessary to prepare readers to deliver enabling support.