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Nanomaterials for Biomedical and Bioengineering Applications
by Rabia Javed Jen-Tsung Chen Ali Talha KhalilThis book accumulates the most recent advancements in the field of bioengineering regarding hybrid science named nanobiotechnology and enriches the readers with vast and comprehensive knowledge about different biomedical applications of nanomaterials. It includes drug and gene delivery, tissue engineering, antimicrobial properties, hyperthermia, cancer therapy, bioimaging, biosensing, photoablation therapy, etc., utilizing the potential of different nanomaterials that are helpful for the well-being of diseased individuals. Furthermore, the concerns about multidrug-resistant microorganisms are increasing daily in the healthcare system. Since conventional therapies fail to combat various infectious diseases, novel nanotechnology techniques provide an alternative approach to developing innovative biomaterials. The novel features of nanomaterials need to be exploited for use in the biomedical engineering domain. They should be fabricated so that the novel multifunctional nanomaterials notonly improve drug efficacy but also reduce their side effects. Moreover, a detailed understanding of the nanotoxicological effects of promising biomedical nanomaterials should necessarily be explored using the cell culture approach. Corona of nanomaterials should be investigated in detail to determine its fate in the biological system regarding safety concerns. This is the most important feature that is novel and explored in this book and would be very helpful for customers like clinicians, scientists, engineers, and technicians who will gain extensive knowledge from this book and work together to get the desired results in the healthcare sector.
Nanomaterials in Healthcare
by Rohit Srivastava Sujit Kumar Debnath Rajendra PrasadThis cutting-edge reference book discusses the biomedical applications of nanomaterials. It covers different types of nanoparticles, such as polymeric nanoparticles, lipoidal nanoparticles, and metallic nanoparticles. It discusses the current trends and challenges in the development of safe biomedicines. The book reviews FDA-approved medicines, nanohybrid systems for early-stage diagnosis and treatment of diseases, advanced approaches of cost-effective bio-imaging, and theragnostics. It also covers the basic design and fundamental understanding of surface-engineered biomedicine. The book is meant for experts in the healthcare industry as well as post-graduates in biomedical engineering and nanotechnology.
Nanotechnology Based Advanced Medical Textiles and Biotextiles for Healthcare
by Vivek Dave Prashansa Sharma Devsuni Singh Suman PantThis book provides systematic coverage of research into medical and biotextiles based on nanomaterials as applicable in healthcare. Divided into three sections, it explains manufacturing, properties, types, and recent developments in nanotechnology based medical textiles backed by case studies. It includes a wide range of different clinical applications of biotextiles for healthcare including nanotextile scaffolds, nano-based artificial organs, surgical sutures, enzymatic assisted enhanced biotextiles, tissue engineering or drug delivery system via nanofibers, and so forth.Features: Provides strong and broad overview of medical applications in the field of nano and biotextiles. Highlights different approaches, recent research, and emerging innovations. Covers designing or developing nanomaterials based antiviral surface disinfectants with self-cleaning property. Reviews different applications of nano based medical textiles such as deodorizing or pH control clothing for hygiene maintenance. Includes the real-life applications based descriptive case studies that offer a diverse range of perspectives. This book is aimed at researchers and graduate students in textile technology and engineering, and medical textiles.
Nanotechnology Based Delivery of Phytoconstituents and Cosmeceuticals
by Deep Pooja Hitesh KulhariThis book explores the role of nanotechnology in the delivery of natural phytoconstituents and cosmeceuticals. It presents polymeric nanocarriers, lipid-based nanocarriers, metal/metal oxide nanocarriers, protein nanocarriers, and dendrimers for the delivery of phytoconstituents. Further, it focuses on the usage of phytocompounds in various cosmeceutical products and nano delivery technologies used in the delivery of various cosmeceuticals. Finally, the book reviews the toxicity issues of nanoparticles in the delivery of phytoconstituents and cosmeceuticals and regulatory aspects for clinical applications of nano phytomedicines. This book is helpful for academicians and researchers working in pharmaceutical sciences, nano science, material science, plant science, and cosmetic science.
Narbentypen in der Narbentherapie: Leitfaden für die Ergotherapie und Physiotherapie (essentials)
by Bianca PetersNach einer Operation, einem Gewebstrauma oder auch nach Bestrahlung kann es zu auffälligen Narben mit wulstigem, atrophem oder auch fibrotischem Wachstum kommen. Treten hierbei mittel- bis langfristig Beschwerden bei Patient*innen auf, so sollte die jeweilige Narbe entsprechend behandelt werden. Tiefergehende Kenntnisse über die Hautschichten und Wundheilungsstörungen sind für die zielgerichtete Behandlung hilfreich. Im vorliegenden essential werden wichtige Narbentypen und deren Besonderheiten schrittweise erklärt. Konkrete Vorgehensweisen bei schlecht heilenden, schmerzenden, oder trockenen und juckenden Narben werden besprochen.Den kostenlosen Zugang zum Online-Kurs finden Sie direkt im Buch.
National Health Services of Western Europe: Challenges, Reforms and Future Perspectives (Routledge Studies in Health and Social Welfare)
by Guido Giarelli Mike SaksThis book draws on research within neo-Weberian and neo-institutionalist perspectives to critically analyse National Health Services (NHSs) in Western Europe. Exploring the challenges posed by neo-liberal policies, it also looks at the impact of the role of the state, the medical profession, the public and the medical–industrial complex in their development. Bringing together a top-line range of expert international contributors, this book includes national studies from three European macro-regions: Britain, Scandinavia and the Mediterranean. In the first part, the NHSs of each country considered are examined historically and in a contemporary context in face of emerging challenges – from cost containment to governance. The second part looks across the macro-regions at the influence of the main actors involved in their evolution and sustainability. Comparing and contrasting the NHSs of Western Europe, the book ends with a discussion of future directions. This book makes a vital contribution at a time when health services globally have been under great pressure in the wake of the COVID-19 pandemic. It is written for academics and advanced students of healthcare, management, public policy, social policy and sociology – in addition to health professionals and policymakers.
A Natural History of the Emirates
by John A. BurtFor many people, thoughts of the United Arab Emirates conjure images of ultramodern skyscrapers and rolling sand dunes. However, the Emirates are a rich mosaic of ecosystems and habitats that support surprisingly diverse communities of organisms, and there is growing awareness of the importance of these previously underappreciated natural assets. A Natural History of the Emirates provides a comprehensive overview of the unusual environmental setting of this young nation, and surveys the major ecosystems and the marine and terrestrial organisms occurring across the nation. From freshwater streams in the hyperarid Hajar Mountains to the world’s most temperature-tolerant coral reefs, the UAE is home to an astounding variety of uniquely adapted organisms that are providing insights into climate change and how organisms cope with and respond to extreme environmental conditions. The book closes with a section on human interactions with this unique environment, and proposes initiatives to ensure the protection of these unique natural assets into the future. This is an open access book.
Natural Products and their Bioactives in Antidiabetic Drug Discovery
by Kanti Bhooshan Pandey Maitree Suttajit Pinar AtukerenNatural Products and their Bioactives in Antidiabetic Drug Discovery Enables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetes Natural Products and Their Bioactives in Antidiabetic Drug Discovery provides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters. Part one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds. Written by a global team of experts in the field, Natural Products and their Bioactives in Antidiabetic Drug Discovery covers sample topics such as: Obesity risk factor in patients with T1DM and possible role of nutritional therapy in its management Use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM Effectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials Implementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds Various antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy Effects of natural products on genetics of gestational diabetes With comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, Natural Products and Their Bioactives in Antidiabetic Drug Discovery is an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology.
Natural Remedies for Mental and Emotional Health: Holistic Methods and Techniques for a Happy and Healthy Mind
by Brigitte Mars Chrystle FiedlerA self-care guide to treating mental, emotional, and neurological conditions• Explores common mental health concerns and stress-related issues—such as anxiety, depression, anger, insomnia, brain fog, and trauma—and shares remedies and practices to address and heal their root causes • Examines the influence of diet and nutrition on mental health and the benefits of specific foods, herbs, supplements, essential oils, and self-care techniques • Details holistic remedies for neurological conditions, such as ADHD, epilepsy, addiction, bipolar disorder, PTSD, multiple sclerosis, Parkinson&’s disease, traumatic brain injury (TBI), and stroke Mental health and emotional well-being are just as important as physical health. And like physical health, there are many simple ways to improve and support mental wellness with the healing power of herbs and other holistic remedies and practices. In this comprehensive guide to natural methods to maintain a healthy mind, herbalist Brigitte Mars and natural health expert Chrystle Fiedler explore many common mental health concerns and stress-related issues—such as anxiety, depression, panic attacks, anger, insomnia, brain fog, and trauma—and share remedies and practices to address and heal their root causes. Citing recent medical studies, they examine the influence of diet and nutrition on mental health concerns and explore the benefits of specific foods, herbs, supplements, essential oils, and self-care techniques like acupressure, massage, and color therapy. The authors also explore holistic practices and treatments for moving through grief, breaking free from addiction, working with ADHD and epilepsy, supporting chronic conditions like bipolar disorder, PTSD, and Parkinson&’s disease, and recovering from traumatic brain injury (TBI) and stroke. Presenting a wealth of holistic self-care therapies for mental well-being, emotional balance, and neurological health, this guide enables each of us to heal the mind and nurture the soul, two essential keys to a happy, joyful life.
Naturally Selective: Evolution, Orgasm, and Female Choice
by Robert KingResearchers of human behaviour have identified an "orgasm gap": Men usually orgasm during intercourse, whereas women often do not. This book addresses this mystery. The two leading explanations are either that women are “psychologically broken” - Freud’s theory – or badly designed – the “by-product theory.” However, there is a much more compelling third explanation. Evolutionary biology, anatomy, physiology, and direct sex research suggest women have evolved under their own selection pressures and orgasm is a fitness-increasing consequence of such selective factors. This is revealed in their patterns of orgasmic response, which are neither random nor inexplicable.Key Features• Synthesizes decades of peer-reviewed sex research in anatomy, biology, physiology, and behavior.• Engagingly written based on feedback from students, peers, and interested lay persons.• Makes sense of the “orgasm gap” between men and women.• Provides a wider context of human sexual dimorphism and mutual sexual selection.• Balances sex research and real-world research and practical applications.
Nature-Based Allied Health Practice: Creative and Evidence-Based Strategies
by Amy Wagenfeld Shannon MarderThe benefits of interacting with nature for our social, cognitive, and physical wellbeing are well documented. But how practical is it to take therapy into nature, or bring nature into therapy?This evidence-based and accessible guide demonstrates easily workable, creative, tried-and-tested strategies for bringing nature into therapy. It includes simple and fun ready-to-go activity ideas. Using the life-course as a framework, the authors highlight the impact of nature at every stage of human development. From younger children to older adults, anyone can benefit from outdoor therapy, and different therapeutic offerings can be adapted to suit most individuals and groups. Resources are included to help assess a program's readiness to incorporate nature, create plans to take therapy outdoors (or bring the outside in), and evaluate the impact it could have for patients or clients.With testimonials from service users who have felt the benefits of nature-based practices, and case studies highlighting excellence in practice from health and social care professionals across various fields, this book will inspire and empower allied health and mental health practitioners to take their therapy practice outdoors.
Nature-Inspired Methods for Smart Healthcare Systems and Medical Data
by Ahmed M. Anter Mohamed Elhoseny Anuradha D. ThakareThis book aims to gather high-quality research papers on developing theories, frameworks, architectures, and algorithms for solving complex challenges in smart healthcare applications for real industry use. It explores the recent theoretical and practical applications of metaheuristics and optimization in various smart healthcare contexts. The book also discusses the capability of optimization techniques to obtain optimal parameters in ML and DL technologies. It provides an open platform for academics and engineers to share their unique ideas and investigate the potential convergence of existing systems and advanced metaheuristic algorithms. The book's outcome will enable decision-makers and practitioners to select suitable optimization approaches for scheduling patients in crowded environments with minimized human errors.The healthcare system aims to improve the lives of disabled, elderly, sick individuals, and children. IoT-based systems simplify decision-making and task automation, offering an automated foundation. Nature-inspired metaheuristics and mining algorithms are crucial for healthcare applications, reducing costs, increasing efficiency, enabling accurate data analysis, and enhancing patient care. Metaheuristics improve algorithm performance and address challenges in data mining and ML, making them essential in healthcare research. Real-time IoT-based healthcare systems can be modeled using an IoT-based metaheuristic approach to generate optimal solutions.Metaheuristics are powerful technologies for optimization problems in healthcare systems. They balance exact methods, which guarantee optimal solutions but require significant computational resources, with fast but low-quality greedy methods. Metaheuristic algorithms find better solutions while minimizing computational time. The scientific community is increasingly interested in metaheuristics, incorporating techniques from AI, operations research, and soft computing. New metaheuristics offer efficient ways to address optimization problems and tackle unsolved challenges. They can be parameterized to control performance and adjust the trade-off between solution quality and resource utilization. Metaheuristics manage the trade-off between performance and solution quality, making them highly applicable to real-time applications with pragmatic objectives.
Neighbourhoods and Public Health: The Impact of Place in Urban Areas
by Uzma Ajmal Saleha JamalThis book examines the concept of neighbourhood over space and time and understands how neighbourhoods can impact human health and well-being. It discusses the identification of neighbourhood boundaries, features of individual neighbourhoods, and the concept of neighbourhood in some major world as well as Indian cities. Based on extensive research, this study refers to both primary as well as secondary sources of data using various statistical and geo-spatial techniques. The first section of the book focuses on the concept of neighbourhood, concept of neighbourhood unit, methods used in the identification of neighbourhood boundaries and theories related to neighbourhood effects on health. The subsequent section of the book deals with a case study on neighbourhood effects on health in an Indian city. The case study is followed by a comparison of its results with other global studies. This book will be useful to the departments of Geography, Public Health, Sociology and Social Work. It will also be of use to professionals and practitioners like city planners, architects, NGOs, Environmentalists, and urban policy makers.
Neurobiology: Methods and Protocols (Methods in Molecular Biology #2746)
by Sebastian DworkinThis volume will serve as a guide for students in the field of neurobiology, and be a bridge between basic science researchers, doctors, and surgeons in clinical practice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Neurobiology: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Neuroblastoma: Discoveries and Challenges (Pediatric Oncology)
by Shahab Asgharzadeh Frank WestermannThis book provides a state-of-the-art review of the biology, treatment, and other critical aspects of neuroblastoma, reflecting the dramatic advances that have been achieved in understanding and management. Topics are arranged according to the book’s dominant themes of the “seed” (tumor genomics, epigenetics, metabolism, and stem cells) and the “soil” (tumor microenvironment, adaptive and innate immunity, and exosomes) and how both of these influences can serve as rich targets for intervention, whether by targeted molecular therapy or immunotherapy. Therapeutic strategies that are currently in use or under consideration for the future are discussed in detail, with the focus on precision medicine. Further individual chapters are devoted to the biology and genetics of relapsed/refractory neuroblastoma and emerging methods of evaluating tumor burden. Finally, in keeping with the, albeit modest, increase in cure rates in high-risk disease, immune and cellular therapies are reviewed. This coverage of what is becoming a not-so-enigmatic tumor will appeal to a broad readership including both experimental oncologists and clinicians who care for patients with neuroblastoma.
Neurodiversity For Dummies
by John Marble Khushboo Chabria Ranga JayaramanA quick and easy way to understand neurodiversity as written by neurodivergent people and our families Neurodiversity For Dummies is your essential guide in understanding neurodivergent conditions like autism, ADHD, dyslexia, and more. This quick and easy guide is perfect for anyone needing to know more about neurodiversity. And that’s all of us—because recent estimates say that 15-20% of the world’s population have some form of neurodivergence. Your life is filled with neurodivergent people that you know and love, whether you realize it yet or not. It’s time to learn to support and include the neurodivergent among us, and to understand how neurodiversity impacts society and the workplace. This is for the neurodivergent person wanting to thrive in life, for parents and caregivers seeking success for their child, and for teachers who are working to make a difference in their students’ lives. Filled with practical advice, Neurodiversity for Dummies also provides a helping hand to service providers, assistance for workplace managers and colleagues, and understanding for family members and friends. Imagine a world where we all understood ourselves better and appreciated more deeply the differences in others. No matter how your own brain thinks, Neurodiversity for Dummies is for you. Check out this jargon-free introduction for an essential overview. Explore the Spectrum of Neurodiversity: Understand in plain language the world of autism, ADHD, dyslexia, and other neurodivergent conditions. Unlock Hidden Talents: Move yourself beyond common myths and misconceptions to discover how neurodiversity actually works. Learn how neurodiversity has always been with us, why society needs neurodivergent traits, and how neurodiversity can be a wellspring of innovation, creativity, and out-of-the-box thinking. Discover Yourself: Whether you are a neurodivergent person or not, learn how to understand your own normalcy, advocate for your needs, and build meaningful connections with those who think and experience the world differently than you. Change the World Around You: Be empowered through simple steps you can take to create inclusive environments for neurodivergent individuals in your school or workplace. Uncover proven strategies that cultivate a culture of acceptance and respect, where the unique perspectives of all individuals are valued and celebrated. We believe in providing parents with better supports, empowering individuals with information, and shaping a world where we are all seen and understood. With an author team composed of neurodivergent individuals and parents writing together, Neurodiversity for Dummies is an example of the power of neurodiversity when put into action. It’s why we wrote this for you. Don’t miss your chance to embark on this transformative journey. Order your copy of Neurodiversity for Dummies now to better understand yourself and others, and to join the movement that is revolutionizing how we understand and support the diversity of the human mind.
Neuroendocrine Regulation of Mammalian Pregnancy and Lactation (Masterclass in Neuroendocrinology #15)
by David R. Grattan Paula J. BruntonAdaptations to maternal physiology are required for a successful pregnancy outcome. These changes are primarily orchestrated by the mother’s brain and involve multiple neuroendocrine systems. For this book, the editors have gathered internationally recognized experts who have contributed to the major advances in our understanding of different aspects of the neuroendocrine regulation of mammalian pregnancy and lactation. The book begins with a discussion of how pregnancy is recognized and maintained and the role of the placental hormones in supporting key adaptations required for a successful pregnancy. The next few chapters focus on the neuroendocrine adaptations that occur during pregnancy in some key regulatory processes to ensure a sufficient supply of energy and nutrients, protect the fetus from potentially harmful maternal stress hormones, and prepare mammals for birth, milk production, lactation and motherhood. Finally, our current understanding of how the significant peripartum hormonal changes contribute to the mother’s cognitive function and mood is examined. This book provides a broad overview of the finely orchestrated neuroendocrine adaptations that occur in pregnancy and lactation and discusses how such changes contribute to maximizing the likelihood of a positive outcome for mother and infant. Importantly the evidence for involvement of neuroendocrine dysregulation in some pregnancy-related complications, such as preterm birth and perinatal mood disorders is also highlighted. In addition to addressing fundamental mechanisms in the regulation of mammalian pregnancy and lactation, the book includes the most recent advances in the field made possible by utilizing the latest innovative research technologies. Moreover, it provides opinions on optimal experimental approaches, relates findings from experimental animal models with those from humans, and outlines the direction and opportunities for future research in this arena. It is an essential resource for undergraduate students, postgraduate students, and early career researchers embarking upon their journey in the fields of neuroendocrinology, endocrinology, reproductive biology or behavioural neuroscience. It also provides a valuable synopsis for established neuroendocrine researchers and educators, especially those whose interest transcends the nexus between neuroendocrinology and reproductive biology. This is the 15th volume in the International Neuroendocrine Federation (INF) “Masterclass in Neuroendocrinology” series, which aims to illustrate the highest standards and to encourage the use of the latest technologies in basic research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Neuroendocrinology of Behavior and Emotions: Environmental and Social Factors Affecting Behavior (Masterclass in Neuroendocrinology #16)
by Heather K. Caldwell H. Elliott AlbersThis volume highlights current research on how the neuroendocrine system helps to influence emotional states and ultimately behavioral output. Social relationships and context-appropriate behavioral responses are important for the survival of most vertebrate species. These relationships can range from transient social interactions to strong social bonding between sexual partners and social behaviors can be observed and evaluated from the individual- to the group-level. Further, behavioral output is shaped by complex interactions between the physical environment, genetics, experience, and context, and are often modulated by the neuroendocrine system. In this book, experts in the field will provide a sweeping look at novel research in the neuroendocrine regulation of important behaviors ranging from parental care to social homeostasis, with a focus on comparative studies across vertebrate species. The first part of the book is dedicated to theneuroendocrinology of relationships, including the coordination of acoustic signals in songbirds, the complexity of social relationships in primates, and cooperation and parenting in humans. The second part of the book focuses on social behaviors and provides some insights into their regulation, including the neuroendocrine regulation of maternal behavior in rodents, the roles of oxytocin and vasopressin in the modulation of sex-specific social behavior, the interactions between adult neurogenesis, the neuroendocrine system and social behavior, and a consideration of neuroendocrine influences on reproductive decision making across species. The book concludes with a section on environmental influences on neuroendocrine systems underlying behavior, including how social isolation and endocrine disrupting chemicals affect the neuroendocrinology of behavior and emotions. Given its breadth, this volume is appropriate for undergraduate students, graduate students, postdoctoral researchers, and established researchers who are interested in neuroendocrinology and behavior. This is the sixteenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Neurology: A Queen Square Textbook
by Robin Howard Dimitri Kullmann David Werring Michael Zandineurology A fully updated and authoritative neurology resource The Queen Square Textbook has established itself as a favourite companion to clinical neurosciences training and teaching around the world, whilst retaining its role as an invaluable reference guide for physicians and other healthcare professionals working in neurology, general medicine and related specialties. The book continues to reflect the core values essential to the practice of clinical neurology in the 21st century. The third edition has been extensively revised and updated to take account of the rapid pace of progress in the neurosciences and patient care. Contemporary neurology has been changed by the COVID-19 pandemic, the climate emergency and the growing inequalities in healthcare resources. The new edition has been extensively revised to reflect these challenges and affords a greater emphasis on management and rehabilitation whilst continuing to reflect the coherence of a text produced from a single, closely-knit, centre of excellence. Highlights of the new edition include: An updated approach to clinical examination, decision-making and diagnosis New developments in neuroimmunology, pathology and genetics Neuropalliative care Ethical and legal issues in clinical neurology The latest developments in the understanding and management of stroke, movement disorders, epilepsy, cognitive impairment, multiple sclerosis, infections, myelopathy, anterior horn cell disease, disorders of nerve and muscle, neuro-oncology, neurological disorders of hearing, balance and vision, and the neurological care of critical illness, sleep, neuropsychiatry, pain, autonomic and urological disorders. An emphasis on treatment and rehabilitation of the person with a neurological disease The new edition marks a significant transition to reflect contemporary neurological practice during uncertain times. It mirrors the enormous changes in investigation, diagnosis and treatment that have occurred in recent years whilst maintaining the underlying principle that we do not treat diagnoses but, rather, we care for people affected by neurological disease.
NeuroPhytomedicine
by Mithun Singh Rajput Tewarit Sarachana Purnima Dey Sarkar Manan RavalNeurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes. The use of synthetic drugs can have undesirable side effects, making neurotherapeutics challenging. Research on neuroprotection aiming for the utilization of safer natural compounds; phytochemicals specifically – is a cutting-edge approach. NeuroPhytomedicine intends to present readers with a wide-ranging and state-of-the-art appearance at the beneficial properties of phytochemicals on various neurological ailments. It additionally contains sections explaining: • Applications of phyto-nanotechnology in neurological ailments, • Phytoconstituents related deep learning and machine learning-based solutions for neurological disorders, • Epigenetic relevance pertaining to modulation by phytochemicals. The goal of NeuroPhytomedicine is to give readers a thorough and up-to-date look at how phytochemicals affect the brain and neurological illnesses in a way that is helpful for research scholars, academicians, scientists, neuroscientists, physicians, and researchers from the pharmaceutical industry.
Neuropsychiatric Manifestations in Neurological Diseases
by Jong S. KimPsychiatric symptoms (or mood/emotional disturbances) are diverse in patients with neurological diseases, that include depression, anxiety, emotional incontinence, anger, fatigue, and apathy. These symptoms are common; more than 1/3 of the patients suffer from these symptoms. Unfortunately, they have been neglected because 1) unlike other neurological symptoms such as motor dysfunction, speech disturbances or visual field defect, these symptoms are not visible and difficult to be noticed unless they are specifically examined by a physician who is properly educated on this problem 2) they are often not regarded as neurological symptoms either by the patients or their caregivers 3) they are relatively poorly studied by both neurologists and psychiatrists, and accordingly, are unfamiliar to the physicians. Especially, although `depression’ is well known to physicians, other symptoms such as emotional incontinence, anger, fatigue or apathy are not appropriately assessed by physicians, and frequently misdiagnosed as depression. Moreover, there are difficulties in diagnosing depression in patients neurological diseases. For example, the individual items included in depression diagnosis such as sleep disturbances, appetite loss, or fatigue can result from neurological diseases or comorbid physical conditions in patients with neurological diseases. Therefore, a diagnosis of `depression’ should be made cautiously. Finally, it should be understood that the importance of different mood/ emotional syndromes differ among various neurological diseases; for instance, although emotional incontinence and anger occur in as many as 20-30 % of stroke patients, apathy and fatigue are more important symptoms than these for patients with neuro-degenerative disease.In clinical practice, recognizing these symptoms is important because they negatively affect the patients’ quality of life, impair the functional recovery, increase the mortality, and increase the caregiver burden. Nevertheless, unlike other neurological symptoms such as motor/sensory dysfunction, and speech disturbances, they are relatively well managed mostly by pharmacological therapy such as selective serotonin re-uptake inhibitors (SSRI).The phenomenology of these neuropsychiatric symptoms and related factors, pathophysiological mechanism, and treatment strategies should be properly educated for neurologists, psychiatrists and other physicians. The book is written by experts in this field to disseminate important knowledges to neurologists, psychiatrists, psychologists and other physicians and will eventually benefit patients with neurological diseases.
Neuropsychological Consequences of COVID-19: Life After Stroke and Balint's Syndrome (ISSN)
by Jwala Narayanan Anjana Xavier Jonathan Evans Narinder Kapur Barbara WilsonNeuropsychological Consequences of COVID-19 focuses on Anjana’s journey as a COVID survivor following a brain injury that left her with a very rare neuropsychological syndrome called Balint’s syndrome, a disorder associated with difficulties in visual and spatial coordination. It is also the first book of its kind to provide a first-hand account from India on surviving brain injury, from diagnosis, recovery and rehabilitation, providing the therapeutic milieu in the Indian context and exploring cultural influences on rehabilitation.Written jointly by Anjana, her neuropsychologist and the international experts in the field of neuropsychology who were also involved in her diagnosis and care, the book highlights how COVID-19, a virus primarily affecting the respiratory system, can also result in a disabling brain injury. It describes Anjana’s recovery and the rehabilitation she received and provides a deeper understanding of this experience of a very rare condition through the views of Anjana herself. In addition, Anjana’s rehabilitation journey stumbles upon many important themes of rehabilitation including cultural sensitivity, personal identity, resilience, role of family and rehabilitation in a low to middle income country.This book is valuable reading for clinical and neuropsychologists, neurologists, other rehabilitation therapists including physiotherapists, occupational therapists, nurses and social work professionals, particularly those interested in cross cultural rehabilitation. It will also be of interest to students in these fields.
Neuroradiology: A Core Review (A Core Review)
by Prachi Dubey Sathish Kumar Dundamadappa Daniel Thomas Ginet Gul MoonisPrepare for success on the neuroimaging component of the radiology Core Exam! Neuroradiology: A Core Review, 2nd Edition, by Drs. Sathish Kumar Dundamadappa, Prachi Dubey, Daniel Thomas Ginat, and Gul Moonis, is an up-to-date, practical review tool written specifically for the Core Exam. This helpful resource contains 500 image-rich, multiple-choice questions with detailed explanations and annotated images of right and wrong answers, fully revised content, high-yield tables for easy review, and additional eBook questions to ensure you’re ready for the Core Exam or recertification exam.
Neurotrophic Natural Products (Progress in the Chemistry of Organic Natural Products #123)
by A. Douglas Kinghorn Heinz Falk Simon Gibbons Yoshinori Asakawa Ji-Kai Liu Verena M. DirschThis book deals with neurotrophins (NGF, BDNF, NT3, NT4), which can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons. This makes neurotrophins potential therapeutic agents for the treatment of neurodegenerative disorders. However, these proteins have so far been ineffective in clinical trials mostly because they cannot pass the blood-brain barrier owing to their high-molecular weights. Consequently, small molecules that mimic neurotrophins and stimulate the synthesis of endogenous neurotrophins or enhance their neurotrophic actions are expected to be promising alternatives. Small-molecule natural products, which have been used in dietary functional foods or in traditional medicine over the course of human history, have potential to be developed as new therapeutic agents against neurodegenerative conditions such as Alzheimer’s disease. In this book, the authors introduce a variety of natural products possessing neurotrophic properties such as neurogenesis, neurite outgrowth promotion (neuritogenesis), and neuroprotection and focus on the chemistry and biology of several neurotrophic natural products.
Never Better: Two Kids, Their Dad, and His Wife's Ghost
by Gonzalo RiedelHis wife died before their second son turned one. How can he keep her memory alive when there’s so much he wants to forget?There was a time before his wife got sick when Gonzalo could think about other things. They had full lives where death didn’t factor. Where humour was more than a coping mechanism. Life wasn’t all about treatments and recovery, or the emptiness he felt when she died.They had kids together. Young kids. Less than a year after their youngest was born and suddenly he was strapping them both into their car seats to drive to their mother’s funeral.He used to think he was the glue holding the household together. It didn’t take long for him to realize how wrong he’d been. A grieving husband is in no condition to raise kids alone. There were times when he wanted to toss himself into a raging river that would suck him under and bash his skull on the rocks. That’s always an option for another day. For now, he’ll just squash those feelings and drive the kids to daycare.Does it get easier? Of course. But not right away. They say that hope only comes at the end of a long dark journey, but that isn’t entirely true because the journey never really ends. But that means there’s good news: hope is everywhere you look.