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Ethnicity and the Dementias (Third Edition)

by Gwen Yeo Linda A. Gerdner Dolores Gallagher-Thompson

<p>In recent years, the literature on the topic of ethnic and racial issues in Alzheimer’s disease and other dementias has increased dramatically. At the same time, the need for cultural competence in all of geriatric care, including dementia care, is increasingly being acknowledged. Dementia is a large societal problem affecting all communities, regardless of race or ethnicity, and understanding dementia for specific groups is tremendously important for both clinical knowledge and for health planning as a nation. <p>This third edition of Ethnicity and the Dementias offers invaluable background information in this area, while also examining how those suffering from dementia and their family members respond or adapt to the challenges that follow. Thoroughly updated and revised throughout, the book features contributions from leading clinicians and researchers in the field, with particular attention given to genetic and cultural factors related to dementia, effective prevention and treatment strategies, and issues in caregiving and family support. Chapters offer specific recommendations for dementia care in 11 ethnic/racial groups, as well as suggestions for working effectively with LGBTQ+ families. <p>Providing a truly comprehensive resource on ethnicity and dementia, and including reflections on emerging trends and the future of caregiving, this new edition is ideal reading for clinicians, educators, researchers, policy makers, and families, in search of the most current ethnogeriatric findings.</p>

Clinical Cases in Coronary Rotational Atherectomy: Complex Cases and Complications (Clinical Cases in Interventional Cardiology)

by Khung Keong Yeo Reginald Low

This concise practical guide is designed to facilitate the clinical decision-making process in the management of rotational atherectomy procedures by reviewing a number of cases and defining the various diagnostic and management decisions open to clinicians. It will be well illustrated but concise, enabling the reader to obtain relevant information regarding both standard and unusual cases in a rapid, easy to digest format. Each case will also include a narrative description and patient management tips. Rotational atherectomy ('rotablator') is used to treat heavily calcified lesions within coronary arteries at the time of percutaneous coronary intervention (PCI). Lesions that are inadequately treated may not be dilatable by balloons; and stents that are implanted in such lesions are at high risk for acute stent thrombosis and stent failure. However, rotablator therapy is high risk and present unique challenges to the interventionalists. Complications are generally uncommon. However, when they do occur, they tend to be disastrous. In this case book, we present a series of rotablator cases: basic, complex cases, difficult cases, complications and unusual situations. Although PCI operators all have some degree of experience with this therapy, each operator is unlikely to have significant experience given the cost of the device and the risk involved. Therefore, this book will provide interventionalists with a valuable compendium of cases which can help them in the management of patients whom they plan to treat with rotational atherectomy.

Nanoparticulate Drug Delivery Systems: Strategies, Technologies, and Applications

by Yoon Yeo

Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.

Privileged Structures in Drug Discovery: Medicinal Chemistry and Synthesis

by Larry Yet

A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book describes the up-to-date and state-of-the-art methods of organic synthesis that describe the use of privileged structures that are of most interest. Chapters included information on benzodiazepines, 1,4-dihydropyridines, biaryls, 4-(hetero)arylpiperidines, spiropiperidines, 2-aminopyrimidines, 2-aminothiazoles, 2-(hetero)arylindoles, tetrahydroisoquinolines, 2,2-dimethylbenzopyrans, hydroxamates, and bicyclic pyridines containing ring-junction nitrogen as privileged scaffolds in medicinal chemistry. Numerous, illustrative case studies document the current use of the privileged structures in the discovery of drugs. This important volume: Describes the drug compounds that have successfully made it to the marketplace and the chemistry associated with them Offers the experience from an author who has worked in many therapeutic areas of medicinal chemistry Details many of the recent developments in organic chemistry that prepare target molecules Includes a wealth of medicinal chemistry case studies that clearly illustrate the use of privileged structures Designed for use by industrial medicinal chemists and process chemists, academic organic and medicinal chemists, as well as chemistry students and faculty, Privileged Structures in Drug Discovery offers a current guide to organic synthesis methods to access the privileged structures of interest, and contains medicinal chemistry case studies that document their application.

Self-Management of Depression: A Manual for Mental Health and Primary Care Professionals

by Albert Yeung Greg Feldman Maurizio Fava

With growing access to health information, people who suffer from depression are increasingly eager to play an active role in the management of their symptoms. The goal of self-management is to support patients in monitoring and managing their symptoms and provide them with additional resources to promote recovery, enhance quality of life, and prevent relapse. For clinicians, self-management holds promise for improving practice efficiency and efficacy by helping patients maximize their improvement outside of treatment sessions. Self-Management of Depression is written for clinicians who wish to empower their patients to take more active steps to manage depression. Chapters cover care management, self-assessment, exercise, self-help books and computer programs, meditation, and peer-support groups and strategies for how to incorporate self-management into a treatment plan are described. Reproducible handouts to support patients are also available online. This book is relevant to clinical psychologists, psychiatrists, psychiatric nurses, social workers and primary care physicians.

Interventional Nephrology

by Alexander S. Yevzlin Arif Asif Loay Salman

Interventional Nephrology: Principles and Practice describes a very direct approach to clinical problems encountered by the community of care providers who treat chronic kidney disease and dialysis patients. Practical scenarios faced on a day-to-day basis are presented by experts in the field utilizing the latest scientific information. In addition to internal medicine residents, nephrology fellows and practitioners, this comprehensive and useful resource is a must-have for the allied health professionals taking care of patients with hemodialysis and peritoneal dialysis access problems.

Interventional Nephrology: Principles and Practice

by Alexander S. Yevzlin Arif Asif Loay Salman Karthik Ramani Shaker S. Qaqish Tushar J. Vachharajani

This book provides a comprehensive, state-of-the-art overview of interventional nephrology. Similar to the previous edition, this text describes a direct approach to clinical problems encountered by the community of care providers who treat chronic kidney disease and dialysis patients. Practical scenarios faced on a day-to-day basis are presented by experts in the field, utilizing the latest scientific information. The book also features updated therapeutic guidelines and fully revised and new chapters.Written by the foremost authorities in the field, Interventional Nephrology: Principles and Practice, Second Edition is a must-have resource for clinicians and practitioners who treat and manage patients with hemodialysis and peritoneal dialysis access problems.

Dr. Neruda's Cure for Evil

by Rafael Yglesias

A suspenseful novel of ideas that explores the limitations of science, the origins of immorality, and the ultimate unknowability of the human psyche Rafael Neruda is a brilliant psychiatrist renowned for his effective treatment of former child-abuse victims. Apart from his talent as an analyst, he&’s deeply empathetic—he himself has been a victim of abuse. Gene Kenny is simply one more patient that Dr. Neruda has &“cured&” of past trauma. And then Kenny commits a terrible crime. Desperate to find out why, Dr. Neruda must shed the standards of his training, risking his own sanity in uncovering the disturbing secrets of Kenny&’s former life. Structured as actual case studies and steeped in the history of psychoanalysis, Dr. Neruda&’s Cure for Evil is Yglesias&’s most formally and intellectually ambitious novel. This ebook features a new illustrated biography of Rafael Yglesias, including rare photos and never-before-seen documents from the author&’s personal collection.

Handbook of Measurement Error Models (Chapman & Hall/CRC Handbooks of Modern Statistical Methods)

by Grace Y. Yi

Measurement error arises ubiquitously in applications and has been of long-standing concern in a variety of fields, including medical research, epidemiological studies, economics, environmental studies, and survey research. While several research monographs are available to summarize methods and strategies of handling different measurement error problems, research in this area continues to attract extensive attention. The Handbook of Measurement Error Models provides overviews of various topics on measurement error problems. It collects carefully edited chapters concerning issues of measurement error and evolving statistical methods, with a good balance of methodology and applications. It is prepared for readers who wish to start research and gain insights into challenges, methods, and applications related to error-prone data. It also serves as a reference text on statistical methods and applications pertinent to measurement error models, for researchers and data analysts alike. Features: Provides an account of past development and modern advancement concerning measurement error problems Highlights the challenges induced by error-contaminated data Introduces off-the-shelf methods for mitigating deleterious impacts of measurement error Describes state-of-the-art strategies for conducting in-depth research

Towards Universal Health Care in Emerging Economies

by Ilcheong Yi

This book explores how political, social, economic and institutional factors in eight emerging economies have combined to generate diverse outcomes in their move towards universal health care. Structured in three parts, the book begins by framing social policy as an integral system in its own right. The following two parts go on to discuss the opportunities and challenges of achieving universal health care in Thailand, Brazil and China, and survey the obstacles facing India, Indonesia, Russia, South Africa and Venezuela in the reform of their health care systems. The evolution of social policy systems and the cases in this volume together demonstrate that universalism in health care is continuously redefined by the interactions between diverse political forces and through specific policy processes. At a time when international and national-level discourse around health systems has once again brought universalism to the fore, this edited collection offers a timely contribution to the field in its thorough analysis of health care reform in emerging economies.

Color Atlas Of Strabismus Surgery: Strategies and Techniques

by Yi Ning J. Strube Kenneth W. Wright

Strabismus can be devastating to patients, yet often difficult to treat, even for the most seasoned veteran. The Atlas of Strabismus Surgery, Fourth Edition clearly and succinctly shares with the reader strategies and surgical techniques to improve the care of patients, starting with the simple basics and progressing to more complicated procedures. Updated from the successful third edition, the atlas is designed for resident ophthalmologists and experienced strabismologists alike. Complete with hundreds of color illustrations, The Atlas of Strabismus Surgery, Fourth Edition covers the management of a wide range of strabismus disorders, from the relatively simple horizontal strabismus, to the complex cyclo-vertical deviations.

Blockchain Foundations and Applications (SpringerBriefs in Applied Sciences and Technology)

by Xun Yi Xuechao Yang Andrei Kelarev Kwok Yan Lam Zahir Tari

This monograph provides a comprehensive and rigorous exposition of the basic concepts and most important modern research results concerning blockchain and its applications. The book includes the required cryptographic fundamentals underpinning the blockchain technology, since understanding of the concepts of cryptography involved in the design of blockchain is necessary for mastering the security guarantees furnished by blockchain. It also contains an introduction to cryptographic primitives, and separate chapters on bitcoin, ethereum and smart contracts, public blockchain, private blockchain, cryptocurrencies, and blockchain applications.This volume is of great interest to active researchers who are keen to develop novel applications of blockchain in the field of their investigatio. Further, it is also beneficial for industry practitioners as well as undergraduate students in computing and information technology.

Shaping Long-Term Care in Emerging Asia: Policy and Country Experiences (Routledge Advances in Asia-Pacific Studies)

by Vasoontara Sbirakos Yiengprugsawan

Countries are facing increasing life expectancy and a shrinking family size and in effect, this may escalate demands for medical and supportive services. The role of families in providing informal care will remain important. However, the simultaneous decline in the supply of informal caregiving caused by changes in family structure and higher female labour-market participation necessitate the expansion of the public role in care provision. This book analyses the challenges of long-term care (LTC) policy development and implications from advanced LTC systems and a current trajectory in emerging economies in Asia. The book approaches the subject through comparative analysis on what works and what does not to provide insight into public policy options for sustainable LTC provision and financing mechanisms. How the countries adopt different approaches to health and social systems towards LTC development could provide important insight and perspectives into policy options in the region. This book aims at academics, policymakers and practitioners in health, social, and aged care services and could also be used as a teaching resource for undergraduate students in health and social sciences and postgraduate programs in public health, epidemiology, social demography, gerontology, and nursing. The book will be of interest to a wider audience not only on social and health consequences of population ageing but also health and social policy relating to older persons.

Dental Pulp Stem Cells

by Sibel Yildirim

Stem cell technology is moving forward at a tremendous rate. Recent discoveries have surprised even the most expert researchers. While every piece of new data broadens the current knowledge and contributes to this moving forward, the new data also serve as paradigm shifters of fundamental knowledge of cell biology. While the question 'What is a Stem Cell' may now seem to basic to even discuss, there are still some discrepancies, however, between groups in terms of their functional roles. Teeth develop from the ectoderm of the first branchial arch and the ectomesenchyme of the neural crest. Deciduous teeth start to form between the sixth and eighth weeks, and permanent teeth begin to form in the twentieth weeks. Several studies have demonstrated that the pulp from both adult teeth and deciduous teeth contains dental pulp stem cells. Several factors have made them very attractive as a model system for many researchers; they are multipotent, ethically and non-controversially available in large numbers, immuno-compatible, developmentally primitive, easy to isolate and have high expansion potential in vitro. However, many controversies still exist in the field. There are several unanswered questions in the biology of dental pulp and odontoblasts. This new volume in the SpringerBriefs in Stem Cells series presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration.

Esthetic and Functional Management of Diastema

by Esra Yildiz Ugur Erdemir

This book offers detailed guidance on integrated orthodontic, periodontal, and restorative solutions for the treatment of diastema, highlighting the advantages of such a multidisciplinary approach and presenting suitable clinical protocols for esthetic reconstruction and functional improvement. The coverage includes discussion of diagnosis and explanation of important elements of dentofacial, dentolabial, and dental analysis and relevant soft tissue aspects. Clear advice is provided on treatment planning, and the various treatment options are fully described, with consideration of new materials and techniques and attention to timing and sequencing. The book benefits from the inclusion of numerous clinical case photos. It will be an excellent aid to the management of patients in whom correction of diastemas is only possible through multidisciplinary interventions.

The Easy Guide to OSCEs for Specialties (Second Edition): A Step-by-Step Guide to Success, Second Edition

by Dilsan Yilmaz Dominic Pimenta Muhammed Akunjee Nazmul Akunjee Shoaib Siddiqui Syed Jalali

This second edition of the highly successful Easy Guide to OSCEs for Clinical Specialties provides a comprehensive yet succinct resource to get you through each clinical rotation, as well as the Final exam. Compiled by recently qualified doctors who have experienced the new OSCE system first hand, the book covers over 80 OSCE examination stations in a wide range of different subjects. Brand new to this edition are chapters on Psychiatry, non-accidental injury in children, and an ‘On the Wards’ section covering both Anaesthetics and Palliative Care. All management suggestions are updated in line with NICE guidance and evidence-base, and new time-saving, student friendly mnemonics have been added to make the book even more user-friendly. This book will ease the already burdensome workload of medical students, and help them pass their OSCEs to become junior doctors competent in a wide range of different skills in medical fields.

The Politics of Healthcare Reform in Turkey

by Volkan Yilmaz

This book explores the transformation in the healthcare system in Turkey since 2003, which has been portrayed as a benchmark for building universal healthcare systems in emerging market economies. Focussing on healthcare politics in an under-researched developing country context, it fills a significant lacuna in existing scholarship. This study answers these questions: What were the political dynamics that enabled the introduction of healthcare reform in Turkey? What political conflicts did the reform generate? How and to whose benefit have these conflicts been resolved? Drawing on qualitative interviews with a diverse set of actors, Yılmaz explores the actors’ subjective interpretations of the reform, the discourses and strategies they used to influence the reform, and the changing healthcare politics scene. He demonstrates that the reform has been a complex political process within which actors negotiated whether and to what extent healthcare remains a citizenship right or a commodity. This book will appeal to students and scholars of social policy, politics, health policy, public health and sociology.

In Vivo Reprogramming in Regenerative Medicine

by Açelya Yilmazer

This new volume reviews current progress on different approaches of in vivo reprogramming technology. Leaders in the field discuss how in vivo cell lineage reprogramming can be used for tissue repair and regeneration in different organs, including brain, spinal cord, pancreas, liver and heart. Recent studies on in vivo cell reprogramming towards pluripotency are reviewed; examples are given to show its potential in regenerative medicine. In each chapter, the regenerative potential of different in vivo reprogramming approaches is discussed in detail. More specifically, how different tissue failures or damages can be treated with this technology is explained. Examples from various animal models are given and the regenerative potential of in vivo reprogramming is compared to that of cell transplantation studies. The last chapter discusses current challenges of these preclinical studies and gives suggestions in order to improve the current strategies. Future directions are indicated for the transition of in vivo reprogramming technology to clinical settings. This is among the first books in the literature which specifically focuses on the in vivo reprogramming technology in regenerative medicine and these chapters collectively cover one of the most important and exciting topics of regenerative medicine.

Clinical Trial Design

by Guosheng Yin

A balanced treatment of the theories, methodologies, and design issues involved in clinical trials using statistical methods There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. However, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. From practical perspectives, Clinical Trial Design: Bayesian and Frequentist Adaptive Methods provides comprehensive coverage of both Bayesian and frequentist approaches to all phases of clinical trial design. Before underpinning various adaptive methods, the book establishes an overview of the fundamentals of clinical trials as well as a comparison of Bayesian and frequentist statistics. Recognizing that clinical trial design is one of the most important and useful skills in the pharmaceutical industry, this book provides detailed discussions on a variety of statistical designs, their properties, and operating characteristics for phase I, II, and III clinical trials as well as an introduction to phase IV trials. Many practical issues and challenges arising in clinical trials are addressed. Additional topics of coverage include: Risk and benefit analysis for toxicity and efficacy trade-offs Bayesian predictive probability trial monitoring Bayesian adaptive randomization Late onset toxicity and response Dose finding in drug combination trials Targeted therapy designs The author utilizes cutting-edge clinical trial designs and statistical methods that have been employed at the world's leading medical centers as well as in the pharmaceutical industry. The software used throughout the book is freely available on the book's related website, equipping readers with the necessary tools for designing clinical trials. Clinical Trial Design is an excellent book for courses on the topic at the graduate level. The book also serves as a valuable reference for statisticians and biostatisticians in the pharmaceutical industry as well as for researchers and practitioners who design, conduct, and monitor clinical trials in their everyday work.

The Integrative Functions of The Basal Ganglia

by Henry Yin

This volume is the first comprehensive and single-authored book on the functions of the basal ganglia. The goal is to provide a new synthesis of diverse areas of research on the basal ganglia, from cellular mechanisms of synaptic transmission and plasticity to neural circuit mechanisms underlying behavior. A global theory of basal ganglia function incorporating research from the last 40 years is presented. I hope to explain for the first time how the basal ganglia generate behavior, how they contribute to learning and memory, and how impairments in basal ganglia function can lead to neurological and psychiatric disorders. Features The only single-authored book on the basal ganglia with coverage of the latest literature. Spans multiple levels of analysis, from cellular physiology to behavior. Includes coverage of clinical symptoms, encompassing neuropsychology, movement disorders, and psychiatric disorders. Discusses the role of the basal ganglia in learning and memory.

Qualitative Research from Start to Finish

by Robert Yin

This lively, practical text presents a fresh and comprehensive approach to doing qualitative research. The book offers a unique balance of theory and clear-cut choices for customizing every phase of a qualitative study. A scholarly mix of classic and contemporary studies from multiple disciplines provides compelling, field-based examples of the full range of qualitative approaches. Readers learn about adaptive ways of designing studies, collecting data, analyzing data, and reporting findings. Key aspects of the researcher's craft are addressed, such as fieldwork options, the five phases of data analysis (with and without using computer-based software), and how to incorporate the researcher's "declarative" and "reflective" selves into a final report. Ideal for graduate-level courses, the text includes Discussions of ethnography, grounded theory, phenomenology, feminist research, and other approaches. Instructions for creating a study bank to get a new study started. End-of-chapter exercises and a semester-long, field-based project. Quick study boxes, research vignettes, sample studies, and a glossary. Previews for sections within chapters, and chapter recaps. Discussion of the place of qualitative research among other social science methods, including mixed methods research.

Qualitative Research from Start to Finish, Second Edition

by Robert K. Yin

This book will help readers understand the practice of qualitative research--whether they want to do it, teach it, or just learn about it. All the major research phases are encompassed (startup, design, data collection, analysis, and composing), including newly emerging trends. Numerous easy-to-read vignettes show how other scholars have successfully implemented specific procedures. Equally distinctive, the book presents qualitative research as an adaptive craft. The array of choices among different procedures and methods enables readers to customize their own studies and to accommodate different worldviews and genres. New to This Edition: *Stronger discussion of different worldviews (e.g., constructivism, postpositivism, and pragmatism) and how they relate to different methodological choices. *Clearer emphasis on doing a generalized qualitative study, while acknowledging 12 specialized genres (e.g., action-based research, arts-based research, autoethnography, grounded theory, phenomenology, and others). *Expanded discussions of different kinds of qualitative study samples and of mixed methods. *New ideas on how to avoid getting stalled when analyzing qualitative data. *Consideration of an additional way of concluding a qualitative study: by taking action. Pedagogical Features: *Chapters start with an abstract and end with a suggested exercise. *Key terms and concepts appear in boldface throughout the text and are listed in end-of-chapter recaps as well as in the book's glossary. *Sections within each chapter start with a preview box: "What you should learn from this section." *An appendix presents a semester- or yearlong field-based project.

Atlas of Perioperative 3D Transesophageal Echocardiography: Cases and Videos

by Wei-Hsian Yin Ming-Chon Hsiung

This book presents a series of over 50 cases in 3Dtransesophageal echocardiography. In each case, background information isfollowed by a step-by-step approach to patient diagnosis and postoperativeoutcomes. The book's most outstanding highlight consists in over 600illustrations, which mainly focus on 3D transesophageal echocardiography incombination with 2D transesophageal echocardiography, X-ray fluoroscopy andcomputed tomography to demonstrate the various cardiovascular pathologies. Since the echo images obtained in clinic practice are moving images, it alsoincludes more than 450 videos, which effectively supplement the staticillustrations. The atlas is divided into 11 chapters. Chapters 1 through 3describe abnormalities affecting mitral, aortic, tricuspid and pulmonaryvalves, while prosthetic valves are discussed in Chapter 4. Chapter 5 detailsabnormalities of the aorta. Chapters 6-8 examine coronary artery disease,congenital heart disease and cardiomyopathies, while Chapter 9 explores casesof infective endocarditis. Chapter 10 deals with tumor and mass lesions, andthe other cases are collectively addressed in Chapter 11. Offering a valuablenew resource, the book will enhance the usefulness of echocardiography duringoperations as a "third eye" for surgeons.

Atlas of Perioperative 3D Transesophageal Echocardiography: Cases and Videos

by Wei-Hsian Yin Ming-Chon Hsiung

This book presents a series of over 50 cases in 3D transesophageal echocardiography. In each case, background information is followed by a step-by-step approach to patient diagnosis and postoperative outcomes. The book’s most outstanding highlight consists in over 600 illustrations, which mainly focus on 3D transesophageal echocardiography in combination with 2D transesophageal echocardiography, X-ray fluoroscopy and computed tomography to demonstrate the various cardiovascular pathologies. Since the echo images obtained in clinic practice are moving images, it also includes more than 450 videos, which effectively supplement the static illustrations. The atlas is divided into 11 chapters. Chapters 1 through 3 describe abnormalities affecting mitral, aortic, tricuspid and pulmonary valves, while prosthetic valves are discussed in Chapter 4. Chapter 5 details abnormalities of the aorta. Chapters 6-8 examine coronary artery disease, congenital heart disease and cardiomyopathies, while Chapter 9 explores cases of infective endocarditis. Chapter 10 deals with tumor and mass lesions, and the other cases are collectively addressed in Chapter 11. In this second edition, authors add 3-5 new cases at each chapter. Now new technology in 3D TEE rendering technology such as TruVue, a kind of post processing techniques, is also included. Offering a valuable new resource, the book will enhance the usefulness of echocardiography during operations as a “third eye” for surgeons. With the advances in technology, clinicians are using three‐dimensional (3D) transoesophageal echocardiographic imaging is crucial for device selection during the procedure and to assess the functional result after procedure.

Cellular Injury in Liver Diseases (Cell Death in Biology and Diseases)

by Xiao-Ming Yin Wen-Xing Ding

This volume has gathered together some of the world's experts on cell death in liver diseases, covering topics on a variety of types of liver injury. Specifically, the chapters of this volume describe drug and virus-mediated hepatocyte injury, alcohol, lipid and bile acid-induced hepatocyte injury in addition to ischemia-reperfusion-mediated liver injury. The authors link these different types of liver injury to the commonly associated liver inflammation, fibrosis and tumorigenesis. Other topics explored include the various forms of cell death and cell survival pathways that have been identified in the liver, such as apoptosis, necroptosis, pryoptosis and autophagy. This book, along with its companion volume, Molecules, Systems and Signaling in Hepatic Cell Death, provides a thorough and comprehensive discussion on the topic of cell death and liver disease. Cellular Injury in Liver Diseases is an essential addition to the Cell Death in Biology and Diseases series and will appeal to scientists, clinicians and those doing research for drug discovery.

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Showing 53,751 through 53,775 of 54,477 results