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New Technologies for Glutamate Interaction: Neurons and Glia (Neuromethods #2780)

by Maria Kukley

This volume explores the latest technologies used to study the co-existence of neuronal and neuron-glia synapses in the brain. The chapters in this volume are organized into three parts. Part One covers recent advancements in the technical approaches for studying glutamatergic signalling between neurons. Part Two highlights approaches to study the functional role of astrocytes at neuronal synapses. Part Three focuses on fast signalling at neuron-glia synapses, and highlights relevant methods for investigating these unusual synapses, including slice electrophysiology and in vivo gene delivery techniques. In the Neuromethods series style, all chapters contain key advices from experts in the field that are valuable for performing successful experiments on the topic in your laboratory.Cutting-edge and thorough, New Technologies for Glutamate Interactions: Neurons and Glia is a valuable resource for both neuronal and glial physiologists who are interested in learning about and developing new methods to further understand neuronal and neuron-glia synaptic transmission.

New under the Sun: Early Zionist Encounters with the Climate in Palestine

by Dr. Netta Cohen

New under the Sun explores Zionist perceptions of—and responses to—Palestine’s climate. From the rise of the Zionist movement in the late 1890s to the establishment of the State of Israel in 1948, Netta Cohen traces the production of climactic knowledge through a rich archive that draws from medicine and botany, technology and economics, and architecture and planning. As Cohen convincingly argues, this knowledge was not only shaped by Jewish settlers’ Eurocentric views but was also indebted to colonial practices and institutions. Zionists’ claims to the land were often based on the construction of Jewish settlers as natives, even while this was complicated by their alienated responses to Palestine’s climate. New under the Sun offers a highly original environmental lens on the ways in which Zionism’s spatial ambitions and racial fantasies transformed the lives of humans and nonhumans in Palestine.

Newtonian Mechanics (Synthesis Lectures on Engineering, Science, and Technology)

by Sujaul Chowdhury

This book discusses topics related to Newtonian mechanics and is ideal for a one semester course. Introductory topics are first presented including: time, space, and matter; different coordinate systems; vectors; and unit vectors;. The author presents tools such as displacement, velocity, and acceleration to describe projectile motion and uniform circular motion. Newton’s laws of motion and concepts of force and mass are discussed followed by kinetic energy, potential energy, and both conservative and non-conservative forces. This class-tested book also introduces angular displacement, angular speed, and angular acceleration as well as the use of these to describe the motion of particles with constant angular acceleration. Concepts of torque, angular momentum, and rotational inertia are presented to explain the motion of physical pendulum. Motion under central force is also covered and Kepler’s laws are derived.

Next-Generation Cybersecurity: AI, ML, and Blockchain (Blockchain Technologies)

by Keshav Kaushik Ishu Sharma

This book highlights a comprehensive overview of the recent advancements and challenges in the field of cybersecurity with a focus on the integration of artificial intelligence (AI), machine learning (ML), and blockchain technologies. The book targets both researchers and practitioners working in the field of cybersecurity and aims to fill the gap in the current literature by providing a comprehensive and up-to-date examination of the integration of AI, ML, and blockchain in cybersecurity systems. The book has a technical focus and provides an in-depthexamination of the latest developments in the field. It covers a range of topics including the basics of AI, ML, and blockchain, the application of AI and ML in cybersecurity, the use of blockchain in cybersecurity, and the integrationof AI, ML, and blockchain in cybersecurity systems. Each chapter is written by leading experts in the field and provides a thorough and technical overview of the topic, including case studies, examples, and practical applications.

Next-Generation Sequencing Data Analysis

by Xinkun Wang

RNA-seq: both bulk and single-cell (separate chapters) Genotyping and variant discovery through whole genome/exome sequencing Clinical sequencing and detection of actionable variants De novo genome assembly ChIP-seq to map protein-DNA interactions Epigenomics through DNA methylation sequencing Metagenome sequencing for microbiome analysis

The Nexus of Climate Change and Land-use – Global Scenario with Reference to Nepal

by Medani P. Bhandari

The interplay between land use and climate change is a crucial aspect of sustainable development, especially in Nepal. This book delves into the intricate connections between land-use and climate change in Nepal, shedding light on significant challenges and potential opportunities. Nepal, with its diverse topography and ecosystems, is exceptionally susceptible to the impacts of climate change. The distinctive land-use patterns, encompassing agriculture, forest cover, and urbanization, significantly influence the country's climate resilience and carbon balance. However, rapid population growth, urban expansion, and changing land-use practices have led to environmental degradation and a surge in greenhouse gas emissions. The alarming deforestation, driven by agricultural expansion, infrastructure development, and unsustainable logging, has contributed to carbon emissions and the depletion of vital ecosystem services. Consequently, the conversion of forested land into agricultural fields has negatively affected biodiversity, soil erosion, and water resources, intensifying the vulnerability of communities to climate change. Nevertheless, embracing sustainable land-use practices like afforestation, reforestation, and agroforestry holds promise for mitigating the impacts of climate change and enhancing resilience. The promotion of climate-smart agriculture, watershed management, and community-based forestry can aid in conserving ecosystems, sequestering carbon, and improving livelihoods. This study illustrates the intricate relationship between land-use and climate change, emphasizing the importance of striking a balance in land-use practices, conserving forests, and biodiversity, and promoting sustainable agriculture. These efforts are indispensable for achieving climate resilience and sustainable development in Nepal. By addressing the nexus between land-use and climate change, Nepal can pave the way towards a more sustainable and climate-resilient future. The purpose of this book is to present the core concepts of this issue, inspire further research, and propose solutions to mitigate the problems caused by human disturbances in the Earth's ecosystem.

Nick and Tesla and the Secret Agent Gadget Battle: A Mystery with Gadgets You Can Build Yourself (Nick and Tesla #3)

by Bob Pflugfelder Steve Hockensmith

Uncover a secret agent and build spy gadgets with twin sleuths Nick and Tesla in this zany, action-packed middle grade adventure by &“Science Bob&” Pflugfelder!After rescuing a kidnapped heiress and taking down a robot army, 11-year-old twins Nick and Tesla could really use a break. But before they can kick back and relax, the young sleuths discover there's a spy in their midst! Someone in the town of Half Moon Bay is spying on their Uncle Newt, an eccentric inventor. To uncover the true identity of this secret agent, Nick and Tesla must build their own spy gadgets, from burglar alarms and code wheels to a water balloon trap and more. Now in paperback, this third book in the popular Nick and Tesla series features laugh-out-loud jokes, fun illustrations, and five DIY science projects with step-by-step instructions for readers to try at home.

Nick and Tesla and the Super-Cyborg Gadget Glove: A Mystery with Gadgets You Can Build Yourself (Nick and Tesla #4)

by Bob Pflugfelder Steve Hockensmith

Build a super-cyborg gadget glove and save the science museum with twin sleuths Nick and Tesla in this zany, action-packed middle grade adventure by &“Science Bob&” Pflugfelder!Just like their eccentric genius Uncle Newt, 11-year-old twins Nick and Tesla love science—and they can't wait for the grand reopening of the science museum in Half Moon Bay. But when someone sabotages the new Hall of Genius exhibit, the animatronic replicas of history's greatest scientists go haywire. The two young sleuths must engineer their very own DIY super-cyborg gadget glove—complete with a false-alarm alarm, a UV-light secret message reader, and more—to catch the culprit and save the museum. Now in paperback, this fourth book in the popular Nick and Tesla series features laugh-out-loud jokes, fun illustrations, and four DIY science projects with step-by-step instructions for readers to try at home.

No-Body Homicide Cases: A Practical Guide to Investigating, Prosecuting, and Winning Cases When the Victim Is Missing

by Thomas A.(Tad) DiBiase

A practical guide for police, death investigators, and prosecutors, No-Body Homicide Cases: A Practical Guide to Investigating, Prosecuting, and Winning Cases When the Victim is Missing, Second Edition takes an expansive look at both the history of no-body murder cases and the best methods to investigate, solve, and bring them to court. How do you prove someone guilty of murder when the best and primary piece of evidence—the victim’s body—is missing? Exclusively dedicated to the investigation and prosecution of no-body homicide cases, this fully updated Second Edition provides the author’s insight gained from investigating, consulting on, and trying scores of no-body cases throughout the United States. Taking readers step-by-step from the first days of a homicide investigation through the trial, the book explores the history of confessions and discloses the investigative techniques police must use to catch these cunning killers. Chapters review methods criminals have used to dispose of bodies, delving into the psychological profile of the type of defendant who murders someone, then hides the body. Since the last edition published, the number of no-body murder cases investigated has skyrocketed, with more than 50 percent of all no-body murder cases tried and prosecuted have occurred since the year 2000. New to this edition is a chapter on a full, singular high-profile case from start to finish, to illustrate the entire no-body investigative and adjudication process. A sample arrent warrant for a no-body murder case is provided in addition to Chapter 12 updating the prior edition’s nearly 400 case summaries provided to the current figure, as of this publication, of 576 no-body murder trials in U.S. history. No-Body Homicide Cases, Second Edition continues to serve as an essential resource and the "how-to" manual for investigating, prosecuting, and winning no-body murder cases.

Noise and Vibration Mitigation for Rail Transportation Systems: Proceedings of the 14th International Workshop on Railway Noise, 07–09 December 2022, Shanghai, China (Lecture Notes in Mechanical Engineering)

by Xiaozhen Sheng David Thompson Geert Degrande Jens C. O. Nielsen Pierre-Etienne Gautier Kiyoshi Nagakura Ard Kuijpers James Tuman Nelson David A. Towers David Anderson Thorsten Tielkes

This book collects original peer-reviewed papers describing the latest developments in railway noise and vibration from the 14th International Workshop on Railway Noise (IWRN14), held on 7–9 December 2022, in Shanghai, China. It covers a broad range of railway noise and vibration topics, including high-speed rail and aerodynamic noise, wheel and rail noise, curving squeal noise, bridge noise, vehicle interior noise, structure-borne noise, and ground-borne vibration. Further topics such as resilient track forms, wheel out-of-round and polygonalization, rail roughness, corrugation and grinding, etc. are also covered. With the extensive and timely information offered, this book helps scientists and engineers in their daily efforts to identify, understand, and solve problems related to railway noise and vibration and to achieve the ultimate goal of minimizing the environmental impact of railway systems.

Non-axisymmetric Local Stability Loss of a Hollow Cylinder: Three-Dimensional Stability Loss in Time-Dependent Composites (Synthesis Lectures on Mechanical Engineering)

by Surkay D. Akbarov Zafer Kutug Muhammad Yousaf Anwar

The book presents formulations and examples of three-dimensional non-axisymmetric stability in viscoelastic anisotropic cylindrical shells. The most critical stability loss modes are determined by minimizing the critical loads and critical times with respect to the number of half-waves in radial as well as transverse directions. Currently, there is no literature available on three-dimensional local buckling analysis (or localized warpage) that considers non-axisymmetric stability loss in viscoelastic cylindrical shells. The contents of this book provide the formulation for such a stability loss analysis through the framework of the three-dimensional linearized theory of stability. Additionally, as this book addresses the problem by modeling the material as a viscoelastic fibrous composite, it can be applied to carry out buckling analysis in both elastic and viscoelastic cases.Guide to modelling composite viscoelastic shell elements for buckling analysisProvides a framework for defining the failure criterion for viscoelastic materialsCourse material for teaching shell buckling and viscoelastic composites

Non-Coding RNAs: Molecular Tools for Crop Improvement

by Penna Suprasanna Vinay Kumar Ashish Kumar Srivastava

This reference book compiles updated research on non-coding RNAs and their role in producing high-yielding plants with higher productivity under changing climates. Plant non-coding RNAs are emerging as the key regulators of plant responses to climate change and environmental stresses. The book covers the sequencing, identification, prediction, identification, characterization, and targets of non-coding RNAs to engineer high-yielding crops. It also includes in silico tools and databases to study them. Key features: Discusses the different types of non-coding RNAs including lnc-RNAs, siRNA, microRNAs, and tasiRNAs. Covers the role of plant non-coding RNAs in epigenetic regulation of environmental stress response and tolerance. Reviews the role of non-coding RNAs under environmental stresses like drought, water logging, salinity, extreme temperature, UV, heavy metals, and xenobiotics. Explores the use of non-coding RNAs in transgenic crops and genome editing. Describes the biogenesis, history, and classification of non-coding RNAs in plants. The book provides a mix of basic and advanced information for postgraduate students, researchers, and scientists in the fields of plant molecular biology, biotechnology, food security, and agriculture.

The Non-Fundamentality of Spacetime: General Relativity, Quantum Gravity, and Metaphysics (Routledge Studies in the Philosophy of Mathematics and Physics)

by Kian Salimkhani

This book argues that our current best theories of fundamental physics are best interpreted as positing spacetime as non-fundamental. It is written in accessible language and largely avoids mathematical technicalities by instead focusing on the key metaphysical and foundational lessons for the fundamentality of spacetime. According to orthodoxy, spacetime and spatiotemporal properties are regarded as fundamental structures of our world. Spacetime fundamentalism, however, faces challenges from speculative theories of quantum gravity – roughly speaking, the project of applying the lessons of quantum mechanics to gravitation and spacetime. This book demonstrates that the non-fundamentality of spacetime does not rely on speculative physics alone. Rather, one can give an interpretation of general relativity that supports some form of spacetime non-fundamentalism. The author makes the case for spacetime non-fundamentalism in three steps. First, he confronts the standard geometrical interpretation of general relativity with Brown and Pooley’s dynamical approach to relativity theory. Second, he considers an alternative derivation of the Einstein field equations, namely the classical spin-2 approach, and argues that it paves the way for a refined dynamical approach to general relativity. Finally, he argues that particle physics can serve as a continuity condition for the metaphysics of spacetime. The Non-Fundamentality of Spacetime will be of interest to scholars and advanced students working in philosophy of physics, philosophy of science, and metaphysics.

Non-Invasive Health Systems based on Advanced Biomedical Signal and Image Processing (Prospects in Biomedical Engineering and Applications)

by Adel Al-Jumaily Paolo Crippa Ali Mansour Claudio Turchetti

This book contains up-to-date noninvasive monitoring and diagnosing systems closely developed by a set of scientists, engineers, and physicians. The chapters are the results of different biomedical projects and theoretical studies that were coupled by simulations and real-world data.Non-Invasive Health Systems based on Advanced Biomedical Signal and Image Processing provides a multifaceted view of various biomedical and clinical approaches to health monitoring systems. The authors introduce advanced signal- and image-processing techniques as well as other noninvasive monitoring and diagnostic systems such as inertial sensors in wearable devices and novel algorithm-based hybrid learning systems for biosignal processing. The book includes a discussion of designing electronic circuits and systems for biomedical applications and analyzes several issues related to real-world data and how they relate to health technology including ECG signal monitoring and processing in the operating room. The authors also include detailed discussions of different systems for monitoring various conditions and diseases including sleep apnea, skin cancer, deep vein thrombosis, and prosthesis controls. This book is intended for a wide range of readers including scientists, researchers, physicians, and electronics and biomedical engineers. It will cover the gap between theory and real life applications.

Nonequilibrium Statistical Mechanics: An Introduction with Applications

by Biman Bagchi

Nonequilibrium statistical mechanics (NESM), practically synonymous with time-dependent statistical mechanics (TDSM), is a beautiful and profound subject, vast in scope, diverse in applications, and indispensable in understanding the changing natural phenomena we encounter in the physical, chemical and biological world. Although time dependent phenomena have been studied from antiquity, the modern subject, the nonequilibrium statistical mechanics, has its genesis in Boltzmann’s 1872 classic paper that aimed at extending Maxwell’s kinetic theory of gases by including intermolecular interactions. Subsequent development of the subject drew upon the seminal work of Einstein and Langevin on Brownian motion, Rayleigh and Stokes on hydrodynamics, and on the works of Onsager, Prigogine, Kramers, Kubo, Mori, and Zwanzig. One major goal of this book is to develop and present NESM in an organized fashion so that students can appreciate and understand the flow of the subject from postulates to practical uses. This book takes the students on a journey from fundamentals to applications, mostly using simple mathematics, and fundamental concepts. With the advent of computers and computational packages and techniques, a deep intuitive understanding can allow the students to tackle fairly complex problems, like proteins in lipid membranes or solvation of ions in electrolytes used in batteries. The subject is still evolving rapidly, with forays into complex biological events, and materials science. Nonequilibrium Statistical Mechanics: An Introduction with Applications is, thus, an introductory text that aims to provide students with a background and skill essential to study and understand time-dependent (relaxation) phenomena. It will allow students to calculate transport properties like diffusion and conductivity. The book also teaches the methods to calculate reaction rate on a multi-dimensional energy surface, in another such application. For a beginner in the field, especially for one with an aim to study chemistry and biology, and also physics, one major difficulty faced is a lack of organization of the available study material. Since NESM is a vast subject with many different theoretical tools, the above poses a problem. This book lays the foundations towards understanding time- dependent phenomena in a simple and systematic fashion. It is accessible to students and researchers who have basic training in physics and mathematics. The book can be used to teach advanced undergraduates. Some involved topics, like the projection operator technique and mode coupling theory, are more suitable for Ph.D. level.

Noninvasive Physiological Measurement: Wireless Microwave Sensing

by James C. Lin

This book explains the principles and techniques of microwave physiological sensing and introduces fundamental results of the noninvasive sensing of physiological signatures, vital signs, as well as life detection. Specifically, noninvasive microwave techniques for contact, contactless, and remote sensing of circulatory and respiratory movements and physiological volume changes are discussed.Noninvasive Physiological Measurement: Wireless Microwave Sensing, is written by a pioneering researcher in microwave noninvasive physiological sensing and leading global expert in microwaves in biology and medicine. The book reviews current advances in noninvasive cardiopulmonary sensing technology and measurement. It includes measurements of the vital signs and physiological signatures from laboratory and clinical testing. The book discusses the applicable domains and scenarios in which there is an interaction of radio frequency (RF) and microwaves with biological matter in gas, fluid, or solid form, both from inside and outside of the human or animal body. The book also provides examples for healthcare monitoring and diagnostic applications through wearables, devices, or remote contactless sensors for physiological signals and signature, vital signs, and body motion sensing. This book is an essential guide to understanding the human body’s interaction with microwaves and noninvasive physiological sensing and monitoring.This book is intended for researchers and professionals in biomedical, electrical, and computer engineering with an interest in antenna, sensors, microwaves, signal processing, and medical applications. It will also be of interest to healthcare professionals, technologists, and practitioners interested in noninvasive physiological sensing and patient monitoring.

Nonlinear Approaches in Engineering Application: Automotive Engineering Problems

by Reza N. Jazar Liming Dai

This book focuses on the latest applications of nonlinear approaches in engineering and addresses a range of scientific problems. Examples focus on issues in automotive technology with a strong emphasis on application, physical meaning, and methodologies of the approaches. The book’s chapters are written by world-class experts who advance the future of engineering by discussing the development of more optimal, accurate, efficient, cost, and energy-effective systems. Topics covered are of high interest in engineering and physics, and an attempt has been made to expose engineers and researchers to a broad range of practical topics and approaches. Nonlinear Approaches in Engineering Application: Automotive Engineering Problems is appropriate for researchers, students, and practicing engineers interested in the applications of nonlinear approaches to solving engineering and science problems.

Nonlinear Differential Equations and Applications: Portugal-Italy Conference on NDEA, Évora, Portugal, July 4–6, 2022 (CIM Series in Mathematical Sciences #7)

by Hugo Beirão da Veiga Feliz Minhós Nicolas Van Goethem Luís Sanchez Rodrigues

This proceedings volume gathers selected, carefully reviewed works presented at the Portugal-Italy Conference on Nonlinear Differential Equations and Applications (PICNDEA22), held on July 4-6, 2022, at the University of Évora, Portugal.The main focus of this work lies in non-linear problems originating in applications and their treatment with numerical analysis. The reader will also find new advances on topics such as ordinary and partial differential equations, numerical analysis, topological and variational methods, fluid mechanics, operator theory, stability, and more.The Portugal-Italy Conference on Nonlinear Differential Equations and Applications convenes Italian and Portuguese researchers in differential equations and their applications to amplify previous collaboration and to follow and discuss new topics in the area. Reflecting the increasing teamwork involving the two mathematical communities, the conference has been opened to researchers from all nationalities.While researchers in analysis and related fields are the primary readership of this volume, PhD students can rely on this book as a valuable source to keep pace with recent advances in differential equations and cutting-edge applications.

Nonlinear Second Order Elliptic Equations

by Mingxin Wang Peter Y. Pang

This book focuses on the following three topics in the theory of boundary value problems of nonlinear second order elliptic partial differential equations and systems: (i) eigenvalue problem, (ii) upper and lower solutions method, (iii) topological degree method, and deals with the existence of solutions, more specifically non-constant positive solutions, as well as the uniqueness, stability and asymptotic behavior of such solutions.While not all-encompassing, these topics represent major approaches to the theory of partial differential equations and systems, and should be of significant interest to graduate students and researchers. Two appendices have been included to provide a good gauge of the prerequisites for this book and make it reasonably self-contained.A notable strength of the book is that it contains a large number of substantial examples. Exercises for the reader are also included. Therefore, this book is suitable as a textbook for graduate students who havealready had an introductory course on PDE and some familiarity with functional analysis and nonlinear functional analysis, and as a reference for researchers.

Nonlinear Structures & Systems, Volume 1: Proceedings of the 41st IMAC, A Conference and Exposition on Structural Dynamics 2023 (Conference Proceedings of the Society for Experimental Mechanics Series)

by Matthew R. W. Brake Ludovic Renson Robert J. Kuether Paolo Tiso

Nonlinear Structures & Systems, Volume 1: Proceedings of the 41st IMAC, A Conference and Exposition on Structural Dynamics, 2023, the first volume of ten from the Conference brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of Nonlinear Dynamics, including papers on:Experimental Nonlinear DynamicsJointed Structures: Identification, Mechanics, DynamicsNonlinear DampingNonlinear Modeling and SimulationNonlinear Reduced-Order ModelingNonlinearity and System Identification

Not the End of the World: How We Can Be the First Generation to Build a Sustainable Planet

by Hannah Ritchie

This "eye-opening and essential" book (Bill Gates) will transform how you see our biggest environmental problems—and explains how we can solve them. It&’s become common to tell kids that they&’re going to die from climate change. We are constantly bombarded by doomsday headlines that tell us the soil won&’t be able to support crops, fish will vanish from our oceans, and that we should reconsider having children. But in this bold, radically hopeful book, data scientist Hannah Ritchie argues that if we zoom out, a very different picture emerges. In fact, the data shows we&’ve made so much progress on these problems that we could be on track to achieve true sustainability for the first time in human history. Did you know that: Carbon emissions per capita are actually down Deforestation peaked back in the 1980s The air we breathe now is vastly improved from centuries ago And more people died from natural disasters a hundred years ago? Packed with the latest research, practical guidance, and enlightening graphics, this book will make you rethink almost everything you&’ve been told about the environment. Not the End of the World will give you the tools to understand our current crisis and make lifestyle changes that actually have an impact. Hannah cuts through the noise by outlining what works, what doesn&’t, and what we urgently need to focus on so we can leave a sustainable planet for future generations. These problems are big. But they are solvable. We are not doomed. We can build a better future for everyone. Let&’s turn that opportunity into reality.

Novel Approaches in Biopreservation for Food and Clinical Purposes

by Enriqueta Garcia-Gutierrez Natalia Gomez-Torres Sara Arbulu

The aim of "Novel Approaches in Biopreservation for Food and Clinical Purposes" is to provide cutting-edge information on biopreservation methods for both food and medical applications. The book has one chapter dedicated to each major food category (milk and dairy, vegetables, meat, fish, bread, flours and beverages) and brief chapters covering preservation approaches for pharmaceuticals, embryos, gametes, cells and tissues. This book assumes a basic understanding of microbiology and food science, aiming to offer an overview of the most commonly and updated techniques currently used, including protective cultures and fermentation starters, bacterial metabolites, essential oils, bacteriophages or endolysins. By presenting this comprehensive overview, the book aims to advance knowledge in the field of biopreservation and foster its implementation in both food and clinical contexts.

Novel Approaches in Metronomic Chemotherapy for Breast Cancer Treatment

by Manzoor Ahmad Mir

This book provides the latest research and developments in the field of metronomic chemotherapy for breast cancer. It presents the principles and mechanisms of metronomic chemotherapy, preclinical and clinical studies, and the latest developments in drug delivery systems and nanoformulations. The clinical pharmacology of metronomic chemotherapy, including pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions, are also examined.Key Features: Introduces metronomics therapy in the neoadjuvant and adjuvant treatment of breast cancer Explores the potential of metronomics in terms of personalized chemotherapy Present pharmacological bases of metronomic chemotherapy Covers the latest developments in drug delivery systems, nanotechnology, and nanoformulations Discusses antiangiogenic effects and the impact of metronomics on immunity This book is useful for students, researchers, oncologists, pharmacologists, and healthcare experts interested in understanding the clinical potential of metronomic chemotherapy in breast cancer.

Novel Optical Fiber Sensing Technology and Systems (Progress in Optical Science and Photonics #28)

by Mingjiang Zhang Jianzhong Zhang Lijun Qiao Tao Wang

This book highlights recent advances in novel optical fiber sensing technology and systems, using distributed fiber sensing technology based on chaotic lasers. Upon introducing the basic theory of chaotic laser, a novel light source, the book summarizes new frontier technologies, and presents photonic integration and sensing applications. The book elaborates on new technologies of distributed optical fiber sensors and its engineering applications, as well as narrow-linewidth fiber laser for optical fiber sensing. This book is of great reference for researchers and professionals in the area of optics and optoelectronics.

Novel Plant Natural Product Skeletons: Discoveries from 1999-2021

by Yongxian Cheng Dapeng Qin

This book provides an overview of the new plant natural product skeletons discovered from 1999 to 2021. It categorizes these natural products by providing their names, source distributions, structural types, structure characteristics, and bioactivities. A total of 1373 plant products in 99 families are presented, which cover 36 different structure types within the Hypericaceae family of which the majority are alkaloid structures. In addition, it presents the biological profiling in the last 23 years by summarizing the biological activities and potential disadvantages. The new natural products skeleton presented are unprecedented structural scaffolds and could bring new opportunities for biological/pharmaceutical areas and provide new structure templates for synthetic chemists. This book helps readers gain in-depth insight into the past and recent trends of natural products; it also assists those interested in assessing the potential biological function of the natural products.

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