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Measurement Science and Technology in Nuclear Engineering (Nuclear Science and Technology)
by Hong Xia Yongkuo LiuThis book highlights the fundamentals and advances in measurement science and technology applied in nuclear power engineering. Inspection of main parameters is an essential part of the operation and control of nuclear power plants. Measurement science and technology in nuclear engineering have experienced fast upgrades with the rapid advancements in computer science, sensors, lasers, and other related technologies. The book not only describes basic theories and widely used techniques but also presents novel experimental findings, newly applied techniques, and future trends that emerge with the higher and more specialized requirements of today’s nuclear power plants and other nuclear projects. The book serves as a valuable information source for scientists and a good handbook for engineers. It also contains well-arranged questions and exercises after each chapter, which makes it an excellent textbook for undergraduate and graduate students in nuclear science and technology.Additional questions and answers via app: Download the Springer Nature Flashcards app free of charge and use exclusive additional material to test your knowledge.
The Quintessence of Basic and Clinical Research and Scientific Publishing
by Gowraganahalli Jagadeesh Pitchai Balakumar Fortunato SenatoreThe book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated into the text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.
Ecosystem Restoration through Managing Socio-Ecological Production Landscapes and Seascapes (Satoyama Initiative Thematic Review)
by Maiko Nishi Suneetha M. SubramanianThis open access book is a compilation of case studies that provide useful knowledge and lessons that derive from on-the-ground activities and contribute to policy recommendations, focusing on the relevance of social-ecological production landscapes and seascapes (SEPLS) to ecosystem restoration. Building on the concept of SEPLS, the Satoyama Initiative promotes landscape approaches as integrative area-based strategies to bring together diverse stakeholders aiming to balance multiple objectives, including conservation and development, for the benefit of biodiversity and human well-being. Many of the SEPLS case studies from the International Partnership for the Satoyama Initiative (IPSI) offer rich evidence to help guide restoration efforts while advancing relevant knowledge and practices. The book highlights how the efforts in managing SEPLS can contribute to ecosystem restoration and sustainable development, looking at the strategies and approaches by which multiple stakeholders express, negotiate, and embrace their plural value perspectives of nature to restore ecosystems within a landscape or seascape. It begins with an introductory chapter followed by twelve case studies and a synthesis clarifying the relevance of the case study findings to policy and academic discussions. This book will be of interest to scholars, policymakers and professionals in the field related to sustainable development, especially on SDGs 15 and 17.
Hepatitis E Virus (Advances in Experimental Medicine and Biology #1417)
by Youchun WangThis book systematically and comprehensively discusses the biological, epidemiological, and clinical characteristics of the hepatitis E virus (HEV). It presents current knowledge of HEV and explores experimental methods, treatment, and prevention of HEV. First identified in the 1980s and cloned in 1990, HEV is the causative agent of hepatitis E, which mainly occurs in developing regions, such as Southeast Asia, the Middle East, and Africa, and significantly affects the health of the people in these areas. It is estimated that a third of the world’s population has been infected with HEV, which is transmitted via the fecal-oral route and can infect both humans and animals. In the second edition, new chapters are added to demonstrate the lifecycle, morphogenesis, and stem cell culture of hepatitis E virus. Although research on hepatitis E virus has made progress recently, there are still some problems that have not been solved. Those problems are discussed in this edition, which would be helpful for researchers to understand the problems on hepatitis E virus that they have faced. Meanwhile, the epidemiology, transmission, genetic evolution, animal models, treatment, and others in the related chapters of the first version were also updated according to the most recent research progress. The book provides an overview of HEV from benchside to bedside. It is a valuable resource for researchers in the field and those in the pharmaceutical industry developing HEV vaccines, as well as physicians involved in identifying and treating those infected with the virus.
CADD and Informatics in Drug Discovery (Interdisciplinary Biotechnological Advances)
by Mithun Rudrapal Johra KhanThis book updates knowledge on recent advances in computational, biophysical and bioinformatics tools/techniques and their practical applications in modern drug design and discovery paradigm. It also encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas; presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, R&D personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, de novo drug design, pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and systems biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to various stakeholders working in the pharmaceutical and biotechnology industries (R&D), the academic as well as research sectors.
Theoretical Studies on Extended Higgs Sectors Towards Future Precision Measurements (Springer Theses)
by Masashi AikoThis book investigates the physics of the discovered Higgs boson and additional Higgs bosons in the extended Higgs models which includes higher-order quantum corrections. While the 125 GeV Higgs boson was discovered, the structure of the Higgs sector is still a mystery. Since the Higgs sector determines the concrete realization of the Higgs mechanism, the study of its nature is one of the central interests in current and future high-energy physics. The book begins with a review of the standard model and the two-Higgs doublet model, which is one of the representatives of the extended Higgs models. Subsequently, we discuss the studies of the two-Higgs doublet model at the lowest order of perturbation. Following the lowest-order analysis, we study the higher-order electroweak corrections in Higgs physics. After reviewing the renormalization procedure and the higher-order corrections in the decays of the discovered Higgs boson, we discuss the higher-order corrections in the Higgs strahlung process from an electron-positron collision, the decays of the additional charged and CP-odd Higgs bosons in the two-Higgs doublet model. From the series of these studies, it is found that the nature of the Higgs sector can be widely investigated by future collider experiments.
Methods in Cancer Stem Cell Biology
by Said M. Afify Masaharu SenoThis book describes the use of stem cells and cancer stem cell generation in the inflammatory microenvironment (cancer-inducing niche) using induced pluripotent stem cells. It provides step-by-step techniques and manuals for studying stem cell and cancer stem cell generation with different applications in cancer research. The development of induced pluripotent stem cells has provided a new approach to studying cancer initiation by producing cancer stem cells without introducing mutations or foreign genes. The book features the research of the authors’ group, which was the first to generate cancer stem cells from stem cells in the presence of inflammatory conditions. The 20 chapters of this book cover topics such as generating pluripotent stem cells, converting normal stem cells to cancer stem cells, enriching, isolating and evaluating cancer stem cells. Methods for evaluating the characteristics of cancer stem cells and possible therapies against them are also discussed. The book provides easy-to-follow protocols that help researchers in the study of cancer stem cells. Illustrations help readers understand how the method of cancer stem cell generation can be applied as an essential method for assessing the carcinogenic potential of various non-mutagenic compounds. It will be a useful resource for graduate students, researchers, technicians, and physicians working in academic, hospital, and pharmaceutical settings.
Fabrication of Micro/Nano Structures via Precision Machining: Modelling, Processing and Evaluation
by Guoqing Zhang Bin Xu Yanjun Lu Suet ToThis book introduces the cutting-edge technology of micro/nano structure fabrication from precision machining, electrical discharge machining (EDM) and precision grinding and injection molding, the contents of the presented book includes but not limited to the machining process, cutting tool preparation, tool path generation, and surface evaluation. This book provides a variety of feasible fabrication methods and advanced manufacturing techniques for the precision fabrication of micro/nano-structures, especially for complex micro/nano-structures. Since the book focuses on the micro/nano-structure fabrication methods including hieratical micro/nano-structures, graduate students, engineering technicians, and researchers in related areas will benefit from this book; also, someone in related application fields such as biomedicine, communication, optics may be the potential readers of this book.
Synthesis and Applications of Nanomaterials and Nanocomposites (Composites Science and Technology)
by Imran Uddin Irfan AhmadThis book brings together multiple aspects of the recent research conducted in the field of nanotechnology covering topics such as the synthesis of various nanoparticles, nanorods, graphene, graphene oxide-metal composites, characterization of these materials, and ample aspects of various applications including in heavy metal sensing, optoelectronic devices, gas sensing, solar cells, biomedical sensors, role in the drug delivery, and waste-water treatment. The book is of interest to early career researchers, who are trying to grasp multiple aspects of nanomaterials and nanocomposite synthesis and its potential applications.
Detection and Interaction of Single Quantum States (Reports of China’s Basic Research)
by Sishen XieThis book highlights the findings and achievements in the major research plan “Detection and Interaction of Single Quantum States” funded by the National Natural Science Foundation of China (NSFC). The 8-year plan started in 2011 and consisted of 107 projects conducted by Chinese universities and research institutes. The book covers the plan's research background, achievements, and follow-up prospects. The plan aimed to tackle one of the major challenges for researchers worldwide—to establish precise detection and control of single quantum states in time, space, energy, and momentum. The plan integrated precise detection means with the ultrahigh resolution of time, space, and energy, under extreme conditions such as ultrahigh vacuum, ultralow temperature, high magnetic field, and ultrahigh pressure, using interdisciplinary research methods in physics, chemistry, informatics, and materials science. The book focuses on the exploration of new phenomena, theories, and concepts of single quantum states, describes new techniques and methods of single quantum states, and presents the purification and construction of single-quantum-state systems. It is a concise and valuable source of information for researchers in quantum science and graduate students interested in the research field.
Textbook of Forensic Science
by Pankaj Shrivastava Jose Antonio Lorente Ankit Srivastava Ashish Badiye Neeti KapoorThis textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tears, sweat, vaginal fluids, urine, and sweat. It also provides an overview of forensic examination of different types of evidence and also includes comprehensive detailing of forensic ballistics including firearm classification, bullet comparison and matching. Further, it explores the examinations of drugs, chemicals, explosives, and petroleum products. It focuses on the various aspects of forensic toxicology, including the study of various poisons/toxins, associated signs and symptoms, a fatal dose /fatal period of poisons. The book also emphasizes digital and cyber forensics, including classification, data recovery tools, encryption and decryption methods, image, and video forensics.It is a useful resource for graduate and post-graduate students in the field of Forensic Science.
Proceedings of the 2022 12th International Conference on Environment Science and Engineering (Environmental Science and Engineering)
by Xueming ChenThis book consists of selected and presented papers from the 2022 12th International Conference on Environment Science and Engineering (ICESE 2022), which was held in Beijing, China, during September 2–5, 2022. The conference brought together innovative academicians and industrial experts in the field of environmental science and engineering in a common forum to promote their research and developmental activities. It also facilitated interchanging scientific information between researchers, developers, engineers, students, and practitioners working abroad. The book includes topics such as environmental sustainability, sustainable cities, environmental restoration and ecological engineering, water resources and river basin management, water treatment and reclamation, air pollution and control, atmospheric physics, carbon capture and storage, waste minimization, and resource management, among others. This book is a valuable reference for those who work in these fields in academia and industry.
Recent Developments in Energy and Environmental Engineering: Select Proceedings of TRACE 2022 (Lecture Notes in Civil Engineering #333)
by Rafid Al Khaddar S. K. Singh N. D. Kaushika R. K. Tomar S. K. JainThis book comprises select proceedings of the International Conference on Trends and Recent Advances in Civil Engineering (TRACE 2022). It discusses the latest topics related to energy and environmental engineering. The topics covered include green and clean technologies, zero-energy buildings, solar energy, energy conservation and heat recovery, solar architecture, artificial intelligence for sustainable buildings, climate change, and plastic and air pollution. This book is useful for researchers and professionals working in the area of civil engineering and energy and environmental engineering.
Renewable Fuels for Sustainable Mobility (Energy, Environment, and Sustainability)
by Pravesh Chandra Shukla Giacomo Belgiorno Gabriele Di Blasio Avinash Kumar AgarwalThis volume discusses the use of renewable fuels for clean transportation and its applications on internal combustion engines. The contents focus on the key aspects of fuel production processes and its impact on various segments of the transportation sector and for sustainable mobility. Several kinds of fuels are assessed such as biofuels, alcohols, and hydrogen, and their effects on the combustion process are characterized by application. This volume will be of use to those working in academia and industry as well as energy experts and policy makers.
Bone Remodeling and Osseointegration of Implants (Tissue Repair and Reconstruction)
by Andy H. ChoiThis book provides an insight into the latest advances in bone fracture healing and remodeling algorithm and their incorporation into patient-specific finite element models and the use of machine learning and artificial intelligence to predict the bone regeneration and osseointegration process with a certain degree of accuracy. It also examines the applications of numerical models to simulate the fracture healing process, which may prove to be advantageous in determining the optimal mechanical-based treatment or reconstruction after an accident or illness. This book is aimed at medical and dental professionals who are involved in implantology and tissue engineering such as dentists, oral and maxillofacial surgeons, orthopedic surgeons, students, and researchers.
Extracellular Vesicles in Cardiovascular and Metabolic Diseases (Advances in Experimental Medicine and Biology #1418)
by Junjie XiaoThis book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
Rhodophyta Volume 5: Ahnfeltiales, Gigartinales, Sebdeniales, Nemastomatales, Plocamiales, Gracilariales and Rhodymeniales (Marine Algal Flora of China #5)
by Guangce WangThis book is the fifth volume of the “Marine Algal Flora of China-Rhodophyta.” The series has seven volumes covering about 20 orders, 45 families, 173 genera, and 560 species including over 150 species firstly described from China, indicating significant importance to the knowledge of North-Western Pacific marine algal flora. The fifth volume Ahnfeltiales, Gigartinales, Sebdeniales, Nemastomatales, Plocamiales, Gracilariales, and Rhodymeniales. It provides first-hand literatures necessary to phycologists who aimed to study algal taxonomy and diversity, especially in the North Western Pacific region. Almost all species involved are illustrated in detail on morphology, inner structure, habitats, and geographical distribution, based upon herbarium specimens collected along the China coast, and a lot of elaborate pictures are attached inside. This flora will gain our understanding of current Chinese marine red algae, but much research is still necessary to reflect the whole picture of the red algal diversity along the China coast.
Probiotics, Prebiotics, Synbiotics, and Postbiotics: Human Microbiome and Human Health
by Vijay Kothari Prasun Kumar Subhasree RayThis book explains the potential value of microbiome and microbiome composition associated with human health and diseases. The opening chapters describe the current state of knowledge regarding the human microbiome structure, function, and diversity. The mechanisms of action and the various putative uses of human microbiome are then examined specific to healthy and disease conditions. Readers will find detailed information on its manipulation of human microbiome studies as well as its applied and translational aspects in the current field. The latest knowledge on probiotics, prebiotics, synbiotics, and postbiotics is presented, and specific cases to date are discussed. This book features knowledge from leading researchers working on different aspects of the human microbiome and its manipulation for better health. Overall, this book is an excellent source for microbiome researchers and students from all levels seeking the most up-to-date advancements in the field and also to point toward the future directions.
Transportation Systems Technology and Integrated Management (Energy, Environment, and Sustainability)
by Ram Krishna Upadhyay Sunil Kumar Sharma Vikram Kumar Hardikk ValeraThe book highlights the transportation ecosystems and its management with underlying technologies for futuristic freight and passenger movement. The contents include contributions on climate change impact on transportation infrastructure, enhancing multimodal transportation, solar energy in railways, managing public transportation with technology, among others. It also includes chapters of newly developed technologies for the intelligent transport system. This book is a useful guide to those working in academia and industry in transportation technology.
Spatial Optical-Fiber Coupling Technology in Optical-Wireless Communication (Optical Wireless Communication Theory and Technology)
by Xizheng KeThis book analyzes the development of space light-fiber coupling research, highlights its importance, examines the underlying theory and key problems, and elaborates on methods to improve the space light-fiber coupling efficiency. Starting from the basic theory of electromagnetic field, the transmission characteristics of light in optical fibers are expounded, and the coupling characteristics of optical signals of different modes are investigated. The spatial light-fiber coupling techniques such as mode conversion method, lens coupling method, and wavefront distortion correction method are discussed in detail, and the key technologies involved are verified by experiments. This book is suitable for the vast majority of engineering and technical personnel and teachers in colleges and institutions who are engaged in wireless optical communication. It can also be used to train senior undergraduates and graduate students in relevant fields.
Oncology: Genomics, Precision Medicine and Therapeutic Targets
by Hardeep Singh Tuli Mükerrem Betül Yerer AycanThis book describes translational cancer therapeutics and the way forward from clinical and molecular diagnosis to treatment. In addition, genomics alterations, microRNAs, and long non-coding RNAs translate precision medicine for the individualistic therapy of cancer patients. It describes the involvement of various pharmacogenetic factors in pharmacodynamic/pharmacokinetic (PD/PK) modulations of medicines. Indeed, the role of bioinformatics and biostatistics, considering the extensive data analysis serving precision medicine approaches, has also been entertained in the present book. Therefore, intended book demonstrates the successful medical evidence for the use of precision medicine in the treatment of cancer and its future clinical perspectives. It fills the gaps in cancer biology and precision medicine with its up-to-date content and well-designed chapters. It will serve as a valuable resource for science, medical students, and interdisciplinary researchers. It is a very welcome addition for the scientific community, research centers, and university-industry research collaborators to find out a complete capsular package about cancer drug targets, precision, and personalized medicine (including an introduction to cancer cell signaling, genomic alterations, miRNA targeting, pharmacogenetics, biomarkers, and metabolomics in precision medicine, etc.) at a single platform.
Water: Basic Science
by Sheng Meng Enge WangThis book highlights the fundamentals for understanding the essential problems and latest progresses in basic water science. Water is the most abundant, fundamental and important matter in nature. Arguably it is also the material that human beings study the most but misunderstand the most. Compared with the environmental science and engineering research activities on water resources, water pollution and water usage closely related to social problems at the macro level, basic scientific research on water at the molecular level has just emerged, the impact of which is not fully recognized yet. This book is devoted to introducing some important advances in the field of basic water science in past decades, with a particular emphasis on recent results on water and the interactions between water and solid surfaces at the molecular level. Starting from introducing concepts and popular theoretical and experimental methods for basic water research, this book mainly focuses on the atomic composition, electronic structure, and physicochemical properties of water molecules, water clusters and water layers (including surface water layers and water surface layers), rules for water adsorption on metals, oxides, and other typical solid surfaces such as salt, as well as the microscopic processes and mechanisms of water diffusion, wetting, decomposition and phase transformations under a variety of conditions. It is a good reference book for students and researchers in water-related science.
Health Risk Assessment of Environmental Chemicals: Pre-Emptive and Integrated Approaches
by Masami IshidoThis book presents the frontier research of toxicology and health risk assessment of chemicals. First, it provides an overview of the current methods of evaluating safety amounts of chemicals and provides a new aspect of the principle of toxicology. Secondly, it shows recent research where the new method of health risk evaluation is adopted, followed by an integrated health risk assessment of chemicals. Finally, it describes the epigenetic inheritance of chemical impact on health throughout several generations. Estimating the safety amount of chemicals surrounding our lives is not sufficient for health risk evaluation, particularly for carcinogenic compounds, endocrine disruptors, and nano materials. The author’s group has found a family of chemicals linked to ADHD through animal screening and identified its chemical nature using chemoinformatics methods. Based on these new developments, this book proposes to utilize the biomarker common to those chemicals for health risk assessment, independent of exposure routes and physiological dimensions. The book appeals to researchers and students in the field of toxicology, health risk assessment, pharmacology, and public health.
Environmental, Social and Governance and Sustainable Development in Healthcare (Sustainable Development Goals Series)
by Tiffany Cheng Leung Wang-Kin Chiu Cindy Shi-Xiang You Ben Yuk FongThis book applies environmental, social and governance (ESG) to issues of sustainable development in healthcare. ESG reporting has been widely used for some time in the business industry to show the economic, social and environmental responsibilities of companies that aim to achieve superior ESG performance for lower risk, more accountability and transparency. Moreover, public-listed companies in healthcare have been growing in significant numbers in recent years. The application or practice of ESG in healthcare has become a growing trend for these large organisations looking to demonstrate their strengths in areas of financing, operations, sustainability and social responsibilities. Such an approach is essential not only for the long-term development of the companies but also for services delivered by healthcare practitioners. Equally, the implications to Sustainable Development Goal (SDG) 3 is relevant to healthcare worldwide with a growing ageing population, which has led to a great burden of care in many countries, particularly in the public sector. The potential development and expansion in private healthcare services, accelerated by technology advancement, has demanded a new paradigm in the healthcare industry, particularly in business, service delivery and policy. The book examines this paradigm through health in all policies, ESG and SDG 3 objectives, research, training and practice. It is relevant to graduate students and scholars working in areas relating to health, business and the SDGs and is also useful to policymakers and practitioners in healthcare.
Proceedings of the 4th International Symposium on Plasma and Energy Conversion: ISPEC 2022, 14-16 Oct, Foshan, China (Springer Proceedings in Physics #391)
by Dong Dai Cheng Zhang Zhi Fang Xinpei LuThese proceedings highlight the fundamental researches and up-to-data developments on energy conversion and high-voltage application by means of low temperature and atmospheric pressure plasma. In recent years, plasma-assisted energy conversion gains increasing attention as an alternative to thermal-catalysis or electro-catalysis. These proceedings discuss and exchange cutting-edge scientific innovations and technological advances in fields like plasma-enabled synthesis of chemicals and fuels, plasma-enabled the environmental clean-up, plasma-enabled catalysis treatment, in-situ probing of plasma-catalyst interactions and its high-voltage applications, which show great potentials in industrial demands like CO2 hydrogenation, CH4 reforming and nitrogen fixation, plasma deposition, chemical synthesis, VOC abatement and high-voltage insulation.This collection of papers presents the main applications of plasma-induced energy conversion and high-voltage discharge in the form of separate chapters, including cutting-edge studies on conversion technology, complex mechanism simulation, in-situ detection and converged applications by artificial intelligence. These proceedings are suitable for researchers engaged in fields like plasma-catalysis, discharge diagnosis and modelling, chemical modelling and high-voltage applications.The major topics covered in the conference proceedings are:1) Advanced plasma-catalysis conversion technology;2) Advanced in-situ discharge diagnosis technology;3) Advanced in-situ plasma-catalysis characterization;4) Multi-scale or innovative modelling technology;5) High-voltage discharge and application.