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Handbook of Infant Mental Health
by Charles H. ZeanahWidely regarded as the standard reference in the field, this state-of-the-art Handbook offers a comprehensive analysis of developmental, clinical, and social aspects of mental health from birth to the preschool years. Leading authorities explore models of development; biological, family, and sociocultural risk and protective factors; and frequently encountered disorders and disabilities. Evidence-based approaches to assessment and treatment are presented, with an emphasis on ways to support strong parent-child relationships. The volume reviews the well-documented benefits of early intervention and prevention and describes applications in mental health, primary care, childcare, and child welfare settings. The chapter on psychopharmacology has been updated for the paperback edition.
Phenolic Antioxidants in Foods: Chemistry, Biochemistry and Analysis
by Alam ZebPlant foods are an essential part of our daily diet and constitute one of the highest contributors to the world economy. These foods are rich in phenolic compounds, which play a significant role in maintaining our health. This textbook presents a comprehensive overview of the chemistry, biochemistry and analysis of phenolic compounds present in a variety of foods. The text can be used as a singular source of knowledge for plant food science and technology, covering all of the important chemical, biochemical and analytical aspects needed for a thorough understanding of phenolic antioxidants in foods.Phenolic Antioxidants In Foods: Chemistry, Biochemistry, and Analysis is comprised of three sections. The first section covers the basic concepts of antioxidants, their chemistry and their chemical composition in foods, providing a detailed introduction to the concept. The second section covers the biochemical aspects of phenolic antioxidants, including their biosynthetic pathways, biological effects and the molecular mechanism of antioxidant effects in the biological system. This section promotes an understanding of the fundamental biochemical reactions that take place in foods and after digestion and absorption. The third section covers the analytical chemistry used in the analysis of phenolic antioxidants in foods, including the basic analytical procedures, methods for analysis and chromatographic and spectroscopic analyses. This section is significant for aspiring food chemists and manufacturers to evaluate the nature and chemistry of phenolic antioxidants in foods. Featuring helpful quizzes, section summaries, and key chapter points, this textbook is the perfect learning tool for advanced chemistry undergraduates and post-graduates looking to gain a fundamental understanding of phenolic antioxidants in food products.
A Brief History of Pharmacy: Humanity's Search for Wellness
by Bob ZebroskiPharmacy has become an integral part of our lives. Nearly half of all 300 million Americans take at least one prescription drug daily, accounting for $250 billion per year in sales in the US alone. And this number doesn't even include the over-the-counter medications or health aids that are taken. How did this practice become such an essential part of our lives and our health? A Brief History of Pharmacy: Humanity's Search for Wellness aims to answer that question. As this short overview of the practice shows, the search for well-being through the ingestion or application of natural products and artificially derived compounds is as old as humanity itself. From the Mesopotamians to the corner drug store, Bob Zebroski describes how treatments were sought, highlights some of the main victories of each time period, and shows how we came to be people who rely on drugs to feel better, to live longer, and look younger. This accessible survey of pharmaceutical history is essential reading for all students of pharmacy.
Faster Than Light
by George Zebrowski Jack DannShort stories and scientific articles about how we might do interstellar travel.
Selective Nanocatalysts and Nanoscience: Concepts for Heterogeneous and Homogeneous Catalysis
by Adriano Zecchina Silvia Bordiga Elena GroppoFilling a gap in the catalysis and nano literature, this monograph is unique in focusing on both nanostructured heterogeneous and homogeneous catalysis. As such, it describes a selection of heterogeneous catalysts in use, showing that the dimension of the relevant portions of the catalysts are always in the 1-100 nm range, and so may be properly understood as nanomachines for the chemical manipulation of molecules to perform high precision selective synthesis. The prominent international authors then go on to show that the concept of nanoscience can be equally applied to artificial homogeneous catalysts whose active sites are generally considered as "single-sites" having a "molecular" dimension. The result is an excellent overview of such hot topics as nanoparticles, MOFs and more, making this indispensable reading for catalytic and organic chemists, as well as those working on organometallics.
The Development of Catalysis: A History of Key Processes and Personas in Catalytic Science and Technology
by Adriano Zecchina Salvatore CalifanoThis book gradually brings the reader, through illustrations of the most crucial discoveries, into the modern world of chemical catalysis. Readers and experts will better understand the enormous influence that catalysis has given to the development of modern societies.• Highlights the field's onset up to its modern days, covering the life and achievements of luminaries of the catalytic era• Appeals to general audience in interpretation and analysis, but preserves the precision and clarity of a scientific approach• Fills the gap in publications that cover the history of specific catalytic processes
Membrane Potential Imaging in the Nervous System
by Dejan Zecevic Marco CanepariThe book is structured in five sections, each containing several chapters written by experts and major contributors to particular topics. The volume starts with a historical perspective and fundamental principles of membrane potential imaging and continues to cover the measurement of membrane potential signals from dendrites and axons of individual neurons, measurements of the activity of many neurons with single cell resolution, monitoring of population signals from the nervous system, and concludes with the overview of new approaches to voltage-imaging. The book is targeted at all scientists interested in this mature but also rapidly expanding imaging approach.
Documenting Domestication: New Genetic and Archaeological Paradigms
by Melinda A. Zeder Daniel G. Bradley Eve Emshwiller Bruce D. SmithThis volume brings together leading archaeologists and biologists working on the domestication of both plants and animals to consider a wide variety of archaeological and genetic approaches to tracing the origin and dispersal of domesticates.
On Gravity: A Brief Tour of a Weighty Subject
by A. ZeeA brief introduction to gravity through Einstein’s general theory of relativityOf the four fundamental forces of nature, gravity might be the least understood and yet the one with which we are most intimate. From the months each of us spent suspended in the womb anticipating birth to the moments when we wait for sleep to transport us to other realities, we are always aware of gravity. In On Gravity, physicist A. Zee combines profound depth with incisive accessibility to take us on an original and compelling tour of Einstein's general theory of relativity. Inspired by Einstein's audacious suggestion that spacetime could ripple, Zee begins with the stunning discovery of gravity waves. He goes on to explain how gravity can be understood in comparison to other classical field theories, presents the idea of curved spacetime and the action principle, and explores cutting-edge topics, including black holes and Hawking radiation. Zee travels as far as the theory reaches, leaving us with tantalizing hints of the utterly unknown, from the intransigence of quantum gravity to the mysteries of dark matter and energy.Concise and precise, and infused with Zee's signature warmth and freshness of style, On Gravity opens a unique pathway to comprehending relativity and gaining deep insight into gravity, spacetime, and the workings of the universe.
QED: The Strange Theory of Light and Matter (Princeton Science Library #33)
by A. Zee Richard P. FeynmanCelebrated for his brilliantly quirky insights into the physical world, Nobel laureate Richard Feynman also possessed an extraordinary talent for explaining difficult concepts to the general public. Here Feynman provides a classic and definitive introduction to QED (namely, quantum electrodynamics), that part of quantum field theory describing the interactions of light with charged particles. Using everyday language, spatial concepts, visualizations, and his renowned "Feynman diagrams" instead of advanced mathematics, Feynman clearly and humorously communicates both the substance and spirit of QED to the layperson. A. Zee's introduction places Feynman's book and his seminal contribution to QED in historical context and further highlights Feynman's uniquely appealing and illuminating style.
Quantum Field Theory in a Nutshell: Second Edition (In a Nutshell #7)
by Anthony ZeeA fully updated edition of the classic text by acclaimed physicist A. ZeeSince it was first published, Quantum Field Theory in a Nutshell has quickly established itself as the most accessible and comprehensive introduction to this profound and deeply fascinating area of theoretical physics. Now in this fully revised and expanded edition, A. Zee covers the latest advances while providing a solid conceptual foundation for students to build on, making this the most up-to-date and modern textbook on quantum field theory available.This expanded edition features several additional chapters, as well as an entirely new section describing recent developments in quantum field theory such as gravitational waves, the helicity spinor formalism, on-shell gluon scattering, recursion relations for amplitudes with complex momenta, and the hidden connection between Yang-Mills theory and Einstein gravity. Zee also provides added exercises, explanations, and examples, as well as detailed appendices, solutions to selected exercises, and suggestions for further reading.The most accessible and comprehensive introductory textbook availableFeatures a fully revised, updated, and expanded textCovers the latest exciting advances in the fieldIncludes new exercisesOffers a one-of-a-kind resource for students and researchers Leading universities that have adopted this book include:Arizona State UniversityBoston UniversityBrandeis UniversityBrown UniversityCalifornia Institute of TechnologyCarnegie MellonCollege of William & MaryCornellHarvard UniversityMassachusetts Institute of TechnologyNorthwestern UniversityOhio State UniversityPrinceton UniversityPurdue University - Main CampusRensselaer Polytechnic InstituteRutgers University - New BrunswickStanford UniversityUniversity of California - BerkeleyUniversity of Central FloridaUniversity of ChicagoUniversity of MichiganUniversity of MontrealUniversity of Notre DameVanderbilt UniversityVirginia Tech University
Continent in Dust: Experiments in a Chinese Weather System (Critical Environments: Nature, Science, and Politics #10)
by Jerry C. ZeeIn China, the weather has changed. Decades of reform have been shadowed by a changing meteorological normal: seasonal dust storms and spectacular episodes of air pollution have reworked physical and political relations between land and air in China and downwind. Continent in Dust offers an anthropology of strange weather, focusing on intersections among statecraft, landscape, atmosphere, and society. Traveling from state engineering programs that attempt to choreograph the movement of mobile dunes in the interior, to newly reconfigured bodies and airspaces in Beijing, and beyond, this book explores contemporary China as a weather system in the making: what would it mean to understand "the rise of China" literally, as the country itself rises into the air?
Metabolism of Human Diseases
by Martin Zeeb Eckhard Lammert"Metabolism of Human Diseases" examines the physiology of key organs (e. g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The latter include depression, schizophrenia, epilepsy, Parkinson's disease, Alzheimer's disease, migraine, multiple sclerosis, Down syndrome, macular degeneration, glaucoma, asthma, COPD, pneumonia, atherosclerotic heart disease, heart failure, stroke, varicose veins, Sickle cell disease, hyperlipidemia, fever, sepsis, allergies, peptic ulcer, gastroenteritis, lactose intolerance, colon cancer, diabetes, cirrhosis, metabolic syndrome, hypertension, chronic kidney disease, gout, urinary tract infections, kidney stones, dental caries, osteoporosis, osteoarthritis, rheumatoid arthritis, breast cancer and prostate cancer. The book also describes commonly used drugs and explains their molecular targets. It provides the first comprehensive and detailed summary of the metabolism of individual organs and their physiological and pathological functioning. Thus it serves as a useful supplement to previous textbooks of human physiology "Metabolism of Human Diseases" is a must-have, state-of-the-art textbook written by International experts for graduate students, postdocs and scientists in metabolic research, biochemistry, physiology and pharmacy as well as for physicians interested in molecular mechanisms underlying common human diseases.
Assessing Rare Variation in Complex Traits: Design and Analysis of Genetic Studies
by Eleftheria Zeggini Andrew MorrisThis book is unique in covering a wide range of design and analysis issues in genetic studies of rare variants, taking advantage of collaboration of the editors with many experts in the field through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES. Chapters provide details of state-of-the-art methodology for rare variant detection and calling, imputation and analysis in samples of unrelated individuals and families. The book also covers analytical issues associated with the study of rare variants, such as the impact of fine-scale population structure, and with combining information on rare variants across studies in a meta-analysis framework. Genetic association studies have in the last few years substantially enhanced our understanding of factors underlying traits of high medical importance, such as body mass index, lipid levels, blood pressure and many others. There is growing empirical evidence that low-frequency and rare variants play an important role in complex human phenotypes. This book covers multiple aspects of study design, analysis and interpretation for complex trait studies focusing on rare sequence variation. In many areas of genomic research, including complex trait association studies, technology is in danger of outstripping our capacity to analyse and interpret the vast amounts of data generated. The field of statistical genetics in the whole-genome sequencing era is still in its infancy, but powerful methods to analyse the aggregation of low-frequency and rare variants are now starting to emerge.
Kinase Screening and Profiling
by Hicham Zegzouti Said A. GoueliThis volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.
Physik ohne Realität: Tiefsinn oder Wahnsinn?
by H. Dieter ZehBeschreiben die Begriffe der modernen Physik tatsächlich die Realität oder sind sie nur Hilfsmittel und Rechenwerkzeuge? Wie können reale Objekte aus Atomen aufgebaut sein, wenn diese angeblich gar keine realen Eigenschaften vor deren Messung besitzen? In philosophischen und meist allgemein verständlichen Aufsätzen setzt sich der Autor - Begründer des Dekohärenzkonzepts in der Quantentheorie - mit den "faulen Ausreden" auseinander, die Physiker finden, um unerwarteten Konsequenzen, die sich aus ihren eigenen Theorien ergeben, aus dem Weg zu gehen.
Fracture Mechanics
by Alan T. ZehnderFracture mechanics is a vast and growing field. This book develops the basic elements needed for both fracture research and engineering practice. The emphasis is on continuum mechanics models for energy flows and crack-tip stress- and deformation fields in elastic and elastic-plastic materials. In addition to a brief discussion of computational fracture methods, the text includes practical sections on fracture criteria, fracture toughness testing, and methods for measuring stress intensity factors and energy release rates. Class-tested at Cornell, this book is designed for students, researchers and practitioners interested in understanding and contributing to a diverse and vital field of knowledge.
Fracture, Fatigue, Failure and Damage Evolution, Volume 8
by Alan T. Zehnder Jay Carroll Kavan Hazeli Ryan B. Berke Garrett Pataky Matthew Cavalli Alison M. Beese Shuman XiaFracture, Fatigue, Failure and Damage Evolution, Volume 8 of the Proceedings of the 2016 SEM Annual Conference & Exposition on Experimental and Applied Mechanics, the eighth volume of ten from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on a wide range of areas, including: In-situ Techniques for Fracture & Fatigue General Topics in Fracture & Fatigue Fracture & Fatigue of Composites Damage, Fracture, Fatigue & Durability Interfacial Effects in Fracture & Fatigue Damage Detection in Fracture & Fatigue
Inventing Iron Man: The Possibility of a Human Machine
by E. Paul ZehrTony Stark has been battling bad guys and protecting innocent civilians since he first donned his mechanized armor in the 1963 debut of Iron Man in Marvel Comics. Over the years, Stark’s suit has allowed him to smash through walls, fly through the air like a human jet, control a bewildering array of weaponry by thought alone, and perform an uncountable number of other fantastic feats. The man who showed us all what it would take to become Batman probes whether science—and humankind—is up to the task of inventing a real-life Iron Man.E. Paul Zehr physically deconstructs Iron Man to find out how we could use modern-day technology to create a suit of armor similar to the one Stark made. Applying scientific principles and an incredibly creative mind to the question, Zehr looks at how Iron Man’s suit allows Stark to become a superhero. He discusses the mind-boggling and body-straining feats Iron Man performed to defeat villains like Crimson Dynamo, Iron Monger, and Whiplash and how such acts would play out in the real world. Zehr finds that science is nearing the point where a suit like Iron Man’s could be made. But superherodom is not just about technology. Zehr also discusses our own physical limitations and asks whether an extremely well-conditioned person could use Iron Man’s armor and do what he does.A scientifically sound look at brain-machine interfaces and the outer limits where neuroscience and neural plasticity meet, Inventing Iron Man is a fun comparison between comic book science fiction and modern science. If you’ve ever wondered whether you have what it takes to be the ultimate human-machine hero, then this book is for you.
Marine Nitrogen Fixation
by Jonathan P. Zehr Douglas G. CaponeThis book aims to serve as a centralized reference document for students and researchers interested in aspects of marine nitrogen fixation. Although nitrogen is a critical element in both terrestrial and aquatic productivity, and nitrogen fixation is a key process that balances losses due to denitrification in both environments, most resources on the subject focuses on the biochemistry and microbiology of such processes and the organisms involved in the terrestrial environment on symbiosis in terrestrial systems, or on largely ecological aspects in the marine environment. This book is intended to provide an overview of N2 fixation research for marine researchers, while providing a reference on marine research for researchers in other fields, including terrestrial N2 fixation.This book bridges this knowledge gap for both specialists and non-experts, and provides an in-depth overview of the important aspects of nitrogen fixation as it relates to the marine environment. This resource will be useful for researchers in the specialized field, but also useful for scientists in other disciplines who are interested in the topic. It would provide a possible text for upper division classes or graduate seminars.
Cotton: Biotechnological Advances (Biotechnology in Agriculture and Forestry #65)
by Usha Barwale ZehrThe growing global population poses the challenge to the scientific community of doubling or tripling the food, feed and fiber production by the year 2050. Biotechnology can make a significant contribution to this effort. This volume reviews the use of biotechnology in cotton, which is the leading plant fiber crop worldwide and grown commercially in more than 50 countries. Renowned experts highlight the success of Bt cotton, the introduction of second and third generation traits and the impact at all levels of farming. Furthermore, the molecular advances being made in cotton biotechnology and the potential traits that will come to market in the next decade are described in detail.
Biopolymers in Sustainable Corrosion Inhibition
by Saman Zehra Mohammad Mobin Chandrabhan VermaBiopolymers in Sustainable Corrosion Inhibition covers the fundamentals, properties, and applications of biopolymers and considers their superiorities over traditional alternatives. It explores the synthesis, characterization, inhibition mechanism, and applications of biopolymeric anticorrosive materials.Focusing on environmentally friendly corrosion prevention methods, this book demonstrates how biopolymers slow the corrosion rate and avoid economic losses owing to the metallic corrosion on industrial liners, tools, or surfaces. This book covers the sustainable corrosion inhibition potential of biopolymers and their derivatives, including chitosan, cellulose, chitin, starch, and natural gums.This book will be a valuable reference for undergraduate and graduate students and academic researchers in the fields of biopolymers, corrosion science and engineering, environmental science, chemical engineering, green chemistry, and mechanical/industrial engineering.
Dance of the Photons: From Einstein to Quantum Teleportation
by Anton ZeilingerEinstein's steadfast refusal to accept certain aspects of quantum theory was rooted in his insistence that physics has to be about reality. Accordingly, he once derided as "spooky action at a distance" the notion that two elementary particles far removed from each other could nonetheless influence each other's properties—a hypothetical phenomenon his fellow theorist Erwin Schrödinger termed "quantum entanglement."In a series of ingenious experiments conducted in various locations—from a dank sewage tunnel under the Danube River to the balmy air between a pair of mountain peaks in the Canary Islands—the author and his colleagues have demonstrated the reality of such entanglement using photons, or light quanta, created by laser beams. In principle the lessons learned may be applicable in other areas, including the eventual development of quantum computers.
Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites (Fungal Biology)
by Susanne Zeilinger Juan-Francisco Martín Carlos García-EstradaThis volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.
Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 (Fungal Biology)
by Susanne Zeilinger Juan-Francisco Martín Carlos García-EstradaFungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.