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Adipose-Derived Stem Cells: Methods and Protocols (Methods in Molecular Biology #2783)

by Jeffrey M. Gimble Bruce A. Bunnell Trivia Frazier Cecilia Sanchez

Since the publication of the previous editions, there has been increased focus on the use of adipose-derived stromal/stem cells (ASC) and stromal vascular fraction (SVF) cells in three-dimensional hydrogel-based scaffolds for the development of microphysiological systems (MPS) serving as in vitro humanized assays and alternatives to in vivo pre-clinical animal models. This third edition volume discusses of the latest technology and advancements in the field of human-derived ASC and SVF. The chapters in this book are organized into four parts. Part One focuses on human ASC’s isolation, characterization, and differentiation. Part Two describes the isolation and characterization of ASC and SVF from canine, feline, and murine tissues. Part Three looks at hydrogels, scaffolds, and microphysiological systems, and Part Four talks about the new assays and applications using ASC. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Adipose-Derived Stem Cells: Methods and Protocols, Third Edition is a valuable resource for both novice and experts researchers interested in learning more about this important and developing field.

ADME Processes in Pharmaceutical Sciences: Dosage, Design, and Pharmacotherapy

by Alan Talevi Pablo A. Quiroga

Absorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook. Whereas primarily oriented to Pharmacy students and graduates, it can also be useful for scientist from different fields elated to pharmaceutics and pharmacology. (e.g., material scientists, material engineers, medicinal chemists, physicians) who might be working in a positions in pharmaceutical companies or whose work might benefit from basic training in the ADME concepts and related biological background.Pedagogical features such as objectives, keywords, discussion questions, summaries and case studies are included as teaching tools. This book will provide not only general knowledge on ADME processes but also an updated insight on some hot topics such as drug transporters, multi-drug resistance related to pharmacokinetic phenomena, last generation pharmaceutical carriers (nanopharmaceuticals), in vitro and in vivo bioequivalence studies, biopharmaceuticals, pharmacogenomics, drug-drug and food-drug interactions, in silico and in vitro prediction of ADME properties, or chronopharmacokinetic. In comparison with other similar textbooks, around half of the volume would be focused on the relationship between expanding scientific fields and ADME processes. Each of these burgeoning fields has a separate chapter in the second part of the volume, and is written with experts on the correspondent topic, including industrial scientists and academics from USA and UK.Additionally, each of the initial chapters dealing with the generalities of drug absorption, distribution, metabolism and excretion would include relevant, classic examples related to each topic with appropriate illustrations. ADME Processes and Pharmaceutical Sciences is written as a core textbook for courses on pharmaceutical sciences: pharmacology, pharmacokinetics,drug delivery, biopharmaceutics, drug design and medicinal chemistry courses.

Advanced Ceramics (Advances in Material Research and Technology)

by Shadia Jamil Ikhmayies

This book presents the fundamentals of advanced ceramics, their stages of development, types and classifications, advanced processing techniques, properties, sintering, and new forms of applications. It highlights specific examples such as alumina, zirconia, Mg-Al-spinels, silicon carbide, silicon nitride, ceramic composites, and thin films with their specific applications. The book reviews progress in perovskite ceramics, in which the synthesis, processing, characterization, and advanced applications of perovskite ceramics are all thoroughly discussed. In addition, developments of perovskite solar cells, the main factors affecting their stability, current problems, development prospects in the research, and application of perovskite solar cells are all highlighted. This book also includes a review of a particular class of rare-earth-based mixed-metal oxides, namely Ln2B2O7 nanostructures (B = Zr, Sn, and Ce), where advantages and disadvantages of each production technique are addressed along with the properties of as-produced nanostructures. The solar photocatalytic uses of Ln2B2O7 nanostructures such as photodegradation of contaminants are also discussed. Yttria-based transparent ceramics for photonic applications are reviewed, along with a discussion of powder synthesis, green body preparation, sintering, and optical properties. In addition, the fundamentals of electrophoretic deposition of hydroxyapatite incorporated composite coatings on metallic substrates are presented and discussed. The different types of ceramics-based self-healing coatings and their fabrication processes have also been reported and discussed in this book. These include titania, zirconia, titanium-alumina, and zirconia-alumina incorporated with Benzotriazole (BTA) as an inhibitor. Advanced ceramic materials that have been used for the purpose of wastewater treatment including ceramic sorbents, resins, aerosols, and ceramic membranes that have been widely used for wastewater treatment purposes are also discussed in depth.Moreover, the book presents the preparation of geopolymers by microwave treatments and explains how their properties can be tuned using microwaves. Furthermore, the future and perspective of these advanced ceramic materials and their modifications to ensure better efficacy toward environmental remediation purposes are highlighted in this book.

Advanced Dental Metallic Materials (Springer Series in Materials Science #338)

by Rebeka Rudolf Peter Majerič Vojkan Lazić Karlo T. Raić

This book delivers a broad and concise look at advanced metallic materials used for dental applications. Due to their excellent mechanical and biological properties, the use of metallic materials in dentistry has continued since time immemorial. In that sense, this book aims to bring the readers closer to the specific purpose of dental metallic materials meeting specific criteria and materials properties such as biocompatibility, non-toxicity, resistance to corrosion, long-term durability, appropriate strength and toughness, as well as corresponding values of modulus of elasticity. Following a comprehensive introduction to the field, the book discusses topical issues such as the long-term stability of dental titanium implants, processing of cobalt-chrome dental alloys, emerging gold dental alloys, and novel nanofoils used for dental joining. Featuring numerous illustrative examples of experimental outcomes, this book is an ideal resource for materials scientists and metallurgists working on advanced alloys for dental applications.

Advanced Learning and Teaching in Higher Education in India: A Policy-technology-capacity Enabled Approach

by Pallavi Tyagi Neha Zaidi Balamurgan Balusamy Celestine Iwendi

This book comprehensively covers the evolution of advanced learning pedagogy and innovative technologies like open educational resources and blended learning models. It specifically talks about the future of technology-enhanced learning and how advanced technology and government policies together are trying to impact learning outcomes globally. Nowadays in a flexible learning environment, technology plays a significant role in higher education systems. Both educators and students are playing prominent roles in its successful implementation. Advanced learning pedagogy by using technology has not only changed teaching procedures but has also evolved the relationship among multiple stakeholders.The content of the book is neatly segregated into four parts. Part I covers the concept and evolution of digital learning and education technology. This part examines the role of technology in higher education and proposes a toolkit for personalized learning and continuous assessment.Parts II and III creatively represent the innovative teaching techniques and learning models under advance learning pedagogy. Chapters under parts II and III are specially designed to present the more simplistic view of various technology-based advanced learning models and resources like flipped classes, gaming designs for e-learning, etc. Part III of the book also extensively covers various case studies/instructor’s stories of technology enabled learning experiences.Part IV focuses on the evaluation of advance learning pedagogy and tools. It also covers the future of information in learning (like formative analytics) and improved learning outcomes using technology and government initiatives in the form of various future oriented education policies like the Digital Action Education Plan (2021–2027).The wide-ranging content also covers the challenges of implementation of advanced learning pedagogy and offers recommendations to overcome such challenges. The book will grab the attention of the modern (IT-enabled) instructor’s fraternity, and students and researchers in the area of technology and education. The book can be further used by policymakers and educational-technology startups to formulate and design technology-based higher education teaching policies and procedures which are indeed helpful in measuring learning outcomes.

Advanced Mammalian Cell Culture Techniques: Principles and Practices

by K. M. Ramkumar R. Senthilkumar Md Enamul Hoque

This up-to-date book compiles both basic and advanced laboratory techniques of mammalian cell culture. It is divided into four major sections encompassing the basics of cell culture, nucleic acid and protein isolation, cell-staining techniques, and cell transfection and single-cell analysis. The topics include aseptic handling, media preparation, and passaging of cells. The book also outlines downstream assays such as nucleic acid and protein isolation from in-vitro cell cultures. Key Features: • Covers cellular staining using fluorescent dyes, genetic manipulation of cells via transfection, and an introduction to single-cell analyses • Discusses basics in cell culture and downstream applications including gene and protein expression analysis • Includes the principles underlying each of the techniques and provides a detailed methodology to practice • Explores the whole range of techniques – from basic to downstream applications and advanced methods The book is essential for students and researchers in the field of life sciences, biotechnology, genetics, and molecular biology.

Advanced Materials and Manufacturing Techniques for Biomedical Applications (Advances In Manufacturing, Design And Computational Intelligence Techniques Ser.)

by Arbind Prasad Ashwani Kumar Manoj Gupta

ADVANCED MATERIALS and MANUFACTURING TECHNIQUES for BIOMEDICAL APPLICATIONS The book provides essential knowledge for the synthesis of biomedical products, development, nanomaterial properties, fabrication processes, and design techniques for different applications, as well as process design and optimization. In origin, biomaterials can come from nature or be synthesized in the laboratory with a variety of approaches that use metals, polymers, ceramic, or composite materials. They are often used or adapted for various biomedical applications. Biomaterials are commonly used in scaffolds, orthopedic, wound healing, fracture fixation, surgical sutures, artificial organ developments, pins and screws to stabilize fractures, surgical mesh, breast implants, artificial ligaments and tendons, and drug delivery systems. The sixteen chapters in Advanced Materials and Manufacturing Techniques in Biomedical Applications cover the synthesis, processing, design, manufacturing, and characterization of advanced materials; self-healing, bioinspired, nature-resourced, nanobiomaterials for biomedical applications; and manufacturing techniques such as rapid prototyping, additive manufacturing, etc. Audience The book is for engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing techniques. It is also appropriate for upper-level undergraduate and graduate students.

Advanced Materials for Biomedical Applications: Development and Processing (Biomedical Materials for Multi-functional Applications)

by Vivek Sheel Rajput Jasdeep Bhinder

This book provides an insight into the basic fundamentals of the biomaterials used for the biomedical applications, their development and processing techniques. Advanced materials are significantly utilized for the biomedical applications ranging from dental devices to cancer treatment owing to their higher biocompatibility and better interaction with tissues. This book covers the various topics that include basic biocompatibility phenomena, insight to materials science, class of different advanced materials as a biomaterials, development and processing techniques, design and analysis of the developed advanced materials, investigation of its properties and major applications. Recent information regarding the development techniques and methods for improving the properties of the advanced materials in the field of biomedical applications is highlighted in detail. The textbook offers clear explanation of the text in the chapters with self-explanatory figures and tables. It demonstrates the novel methods, opportunities and ideas for developing biomaterials in the field of biomedical applications. It also includes critical review study of the developed advanced materials for biomedical applications in a new summarized form. The inclusion of the discussions on hybrid polymer-based composites and self-healing composite materials offers a special feature in the textbook. It features a thorough overview of the simulation aspect in the biomedical applications. The book features at least 50% of its references from last three–four years’ work in the field of biomaterials and biomedical. The book content adds to the redundancy in the literature work related to biomedical and biomaterials.This book is a valuable resource for academicians, students and scholars from science and engineering background having interest in biomaterials. It is helpful to the biomedical engineering group especially in countries or location where they don’t have access to the major journals.

Advanced Materials for Multidisciplinary Applications

by Marinda Wu Wei Gao Lei Li Yingchun Lu Jingbo Louise Liu

This book provides an overview of recent research in the area of advanced materials for improving human healthcare, protecting the environment and alternative energy resources. The authors analyze and deliver viable technical solutions, demonstrating how chemistry and engineering can collectively solve technical and societal challenges. The book explores innovative technology for the synthesis of complex carbohydrates & glycoproteins, new drug development & delivery, theragnostics of infectious disease and cancer. It also provides insights into the nature of energy extraction, management and usage related to fossil fuels and sustainable energy. The book brings together a group of dynamic and productive scientists, engineers, and other professionals in celebration of the 40th Anniversary of Chinese American Chemical Society. It is a valuable resource for all readers interested in the study of materials to address society's increasing need for electrical and chemical energy.

Advanced Non-Thermal Power Generation Systems (Sustainable Energy Strategies)

by Yatish T. Shah

Generally, sources for power generation are broken down into two categories: thermal and non-thermal. Thermal sources for power generation include combustion, geothermal, solar, nuclear, and waste heat, which essentially provide heat as a means for power generation. This book examines non-thermal (mechanical, electrochemical, nanoscale self-powered, and hybrid) sources of power generation and emphasizes recent advances in distributed power generation systems. Key Features Details recent advances made in wind power, including onshore, offshore, fixed and floating platform, and air wind energy systems, and offers detailed assessments of progress Covers advances in generation of hydropower, exploring dam hydropower, novel wave energy converters, and novel systems and turbines for hydrokinetic energy conversion to power Examines all types of fuel cells and their multi-functional roles, along with hybrid fuel cell systems in complete detail Explores advances in the development of self-powered nanogenerators for use in portable, wearable, and implantable power electronics Focuses on technologies with the best commercial possibilities and provides perspectives on future challenges that need to be solved This book will be of value to all researchers in academia, industry, and government interested in pursuing power generation technologies and seeking a comprehensive understanding of available and emerging non-thermal power generation sources. Readers who are interested in learning about thermal power generation sources can find it in the author’s companion text Advanced Power Generation Systems: Thermal Sources (2023).

Advanced Rail Geotechnology – Ballasted Track

by Buddhima Indraratna Cholachat Rujikiatkamjorn Wadud Salim

Ballast plays a vital role in transmitting and distributing the train wheel loads to the underlying track substructure. The load-bearing capacity, safe train speed, and the levels of noise and vibration, as well as passenger comfort depend on the behaviour of ballast through particle interlocking and the corresponding deformation of this granular assembly. Attrition and breakage of ballast occur progressively under heavy and continual cyclic loading, causing track deterioration and rail misalignment affecting safety, while exacerbating the intensity of track maintenance. In the absence of realistic computational models, the track substructure is traditionally designed using mostly empirical approaches. In this book, the authors present the detailed information on the strength, deformation, and degradation aspects of fresh and recycled ballast under monotonic, cyclic, and impact loading using innovative geotechnical testing devices. A constitutive model for ballast incorporating particle breakage is presented representing a more realistic stress–strain response. The mathematical formulations and numerical models are validated using controlled experimental simulations and fully instrumented field trials. Revised ballast gradation is described to provide greater track resiliency and extended longevity. The book also provides a detailed description of geosynthetics for substructure improvement considering track deterioration caused by particle degradation, fouling, and impeded drainage. New to this second edition are extensive discussions on subgrade soil stabilisation, causes and mechanisms of soil fluidisation (mud pumping) under cyclic loading, and preventive and remedial measures to alleviate undue instability of ballast tracks. This book should prove most beneficial for final-year civil engineering students and for postgraduate teaching and learning. It is an ideal supplement for practising railway engineers and researchers engaged in the challenging tasks of future track design for heavier and faster trains.

Advanced Strategies for Biodegradation of Plastic Polymers

by Ravindra Soni Prasenjit Debbarma Deep Chandra Suyal Reeta Goel

Synthetic plastic offers a wide range of utilities because of its physico-chemical properties, thus the demand for its commercial availability and generation of waste is inevitable. Although the scientists have proved over the years that plastics can be efficiently biodegraded by different potential microorganisms, this sustainable green technology is still in the cocoon phase and overlooked by the industry and government as well. Therefore, this book will showcase the cutting-edge microbial tools to mitigate the plastic waste sustainably in consideration of latest technologies and recent strategic advancements besides discussing the global plastic production and their impacts on environment. It will also provide the present status and future perspectives of the environmental clean-up technologies. Moreover, it is an effort to ascertain the potential areas for large-scale biodegradation or pilot scale or start-up ventures in the field of plastic remediation strategy.

Advanced Synthesis and Medical Applications of Calcium Phosphates (Emerging Materials and Technologies)

by S. S. Nanda Jitendra Pal Singh Sanjeev Gautam Dong Kee Yi

Calcium phosphate materials are used in many medical and dental applications. Advanced Synthesis and Medical Applications of Calcium Phosphates covers the structure, chemistry, synthesis, and properties of both natural and synthetic calcium-based biomaterials and details a variety of medical applications. Depicts the latest advances in using calcium phosphates in bone regeneration and tissue engineering Includes the latest generation of regenerative biomaterials with an integrated perspective combining both research and clinical issues Provides an understanding of the clinical targets and requirements for regenerative medicine Detailing fundamentals through applications, this book helps biomaterials researchers to better understand the clinical targets and requirements for use of these materials for optimal synthesis and development.

Advanced Technologies for Protein Complex Production and Characterization: Volume II (Advances in Experimental Medicine and Biology #1453)

by M. Cristina Vega Francisco J. Fernández

This edited volume discusses the identification, discovery, characterization, structure determination and modeling of multicomponent macromolecular complexes, and as such, it fully complements the first volume (ISBN 978-3-319-27214-6), which targeted methods of recombinant production of protein complexes. This book is divided in 8 sections offering a selection of technologies widely used in the characterization of protein and protein-nucleic acid complexes for different purposes and at different scales. From native electrophoresis methods, that are accessible to any reasonably well-equipped laboratory, to the sophisticated setup required for structure determination by cryo-electron microscopy or X-ray crystallography, this book contains a wide variety of clearly explained analytic and preparative approaches, connected with the production techniques developed on the previous volume. The readers will find an integral connection between this book and the first volume, which ensures a comprehensive and updated discussion of the main topics of the discipline. Taken together, these volumes constitute a cohesive and authoritative source of the research on multicomponent macromolecular complexes. In here, we focus on characterization of protein complexes in the broadest sense, which is not typically covered in other sources. Moreover, all chapters are carefully written by world renowned scientists and active researchers, making this volume ideal, not only as a reference source, but also as a companion book for the daily laboratory work. This book is aimed for a wide range of scientists, from science students to experienced researchers, working on protein and protein-nucleic acid complexes, who need a thorough understanding of protein production and complex characterization.

Advancement of Data Processing Methods for Artificial and Computing Intelligence (River Publishers Series in Computing and Information Science and Technology)

by Seema Rawat V. Ajantha Devi Praveen Kumar

This book emphasizes the applications of advances in data processing methods for Artificial Intelligence in today's fast-changing world, as well as to serve society through research, innovation, and development in this field. This book is applicable to a wide range of data that contribute to data science concerns and can be used to promote research in this high-potential new field. People's perceptions of the world and how they conduct their lives have changed dramatically as a result of technological advancements. The world has been gripped by technology, and the advances that are being made every day are undeniably transforming the planet. In the domains of Big Data, engineering, and data science, this cutting-edge technology is ready to support us.Artificial intelligence (AI) is a current research topic because it can be applied to a wide range of applications and disciplines to solve complicated problems and find optimal solutions. In research, medicine, technology, and the social sciences, the benefits of AI have already been proven. Data science, also known as pattern analytics and mining, is a technique for extracting useful and relevant information from databases, enabling better decision-making and strategy formulation in a range of fields. As a result of the exponential growth of data in recent years, the combined notions of big data and AI have given rise to many study areas, such as scale-up behaviour from classical algorithms. Furthermore, combining numerous AI technologies from other areas (such as vision, security, control, and biology) in order to build efficient and durable systems that interact in the real world is a new problem. Despite recent improvements in fundamental AI technologies, the integration of these skills into larger, trustworthy, transparent, and maintainable systems is still in its development. Both conceptually and practically, there are a number of unanswered issues.

Advancement of Melatonin Research in Plants: Multi-Faceted Role in Regulating Development and Stress Protection

by Aryadeep Roychoudhury

Melatonin (N-acetyl-5-methoxytryptamine) is a widely studied biomolecule, and its function has been investigated in bacteria, mammals, birds, amphibians, reptiles, fish and plants. Melatonin research in plants the last five years has attained an exponential growth phase and the number of publications related to phytomelatonin has significantly increased in present times. All this research is directed towards establishing multifarious roles of melatonin in plants, including the promotion of seed germination and seedling growth, influencing plant development and senescence, alteration of flowering and fruiting time and grain yield, modulating circadian rhythms, improving resistance against biotic stress as well as tolerance to abiotic stress, reducing oxidative stress, and stimulating plant immune response. However, to date, an exhaustive book, solely and exclusively dedicated to melatonin research on various aspects of plant biology, has not been published by any renowned publisher or is available in the market. Keeping all these facts in mind, this book aims to compile the most recent developments in the arena of melatonin-mediated regulation of plant physiology under optimal and sub-optimal conditions. This book will initiate and introduce the readers to the state-of-the-art developments and trends in this field of study and will largely cater to the scientific need of scientists engaged in melatonin research across the globe. The book will be unique of its kind and will draw the attention of scientific and research communities engaged in the field of melatonin research.The key features of this book: Authors will address the topics which would provide advances in the understanding of diverse functions of melatonin in plants, encompassing almost all the aspects that have been investigated so far Integrate the overall mechanistic function of melatonin, genomics and proteomics tools, and genetic engineering to manipulate endogenous melatonin levels, thus giving a holistic view of plant-level studies under normal or challenging situations Largely help the readers to design future research programs in exploiting melatonin as a protective agent to develop climate-resilient and pathogen-resistant plants Benefit the crop protection program and ensure food security Chapters will be supplemented with ample illustrations and figures This book will be beneficial to research scholars and Ph.D. students involved in melatonin research and working on stress physiology, stress proteins, genomics, proteomics and genetic engineering in different universities and research institutes all over the world. The book can also be used as an advanced reference book for the coursework of research and master’s level students. It will be of use to people involved in improving plant growth and yield, as well as the performance of plant species in the face of climate change and pathogen infection, using melatonin as the prime protective agent and signaling molecule. Although the book will directly benefit the academic and scientific community, it will also indirectly draw the attention of industries or companies that manufacture or sell chemical products, since the book will highlight in detail the antioxidative potential of melatonin. This will create impetus at the industrial level for the isolation and synthesis of melatonin as a beneficial chemical agent. Applying melatonin as an ameliorating agent against different stresses at the field level will also increase the demand for this chemical among the farmers and will promote large-scale sales and utilization of melatonin for ensuring crop protection and increasing yield.

Advancement of Optical Methods and Fracture and Fatigue, Volume 3: Proceedings of the 2023 Annual Conference on Experimental and Applied Mechanics (Conference Proceedings of the Society for Experimental Mechanics Series)

by Cosme Furlong Chi-Hung Hwang Gordon Shaw Ryan Berke Garrett Pataky Shelby Hutchens

Advancement of Optical Methods and Fracture and Fatigue, Volume 3 of the Proceedings of the 2023 SEM Annual Conference & Exposition on Experimental and Applied Mechanics, the third volume of five from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of Experimental Mechanics, including papers in the following general technical research areas:Extreme EnvironmentsInterfacial FractureIntegration of Models & ExperimentsMechanics of Energy & Energetic MaterialsIntegration of Models & ExperimentsIn Situ Techniques for Fatigue & FractureMicroscale & Microstructural Effects on Mechanical BehaviorCharacterization Across Length ScalesExtreme Conditions & Environmental EffectsDamage, Fatigue and FractureStructure, Function and Performance

Advancement of Science and Technology in Sustainable Manufacturing and Process Engineering (Green Energy and Technology)

by Kibret Mequanint Assefa Asmare Tsegaw Zenamarkos Bantie Sendekie Birhanu Kebede Ephrem Yetbarek Gedilu

This book presents current research on sustainable development issues and recent manufacturing and process engineering advances. Topics covered range from postharvest technologies to sustainable utilization of natural resources and supply chain integration to the design of renewable energy systems. The book provides researchers, engineers, industry professionals, graduate students, and practitioners with state-of-the-art research on the efforts being made toward sustainability in developing countries.

Advancements in Microbial Biotechnology for Soil Health (Microorganisms for Sustainability #50)

by Ravi Kant Bhatia Abhishek Walia

This edited book covers the latest trends to improve soil health. It provides an easy-to-understand information to the readers. This book acts as a reference book for various agronomists and research scholars working in the field of agriculture. This edited book covers advanced technologies and practices carried out worldwide to improve soil health. In the present scenario, it is very important to save soil health and replenish it in a sustainable manner from various anthropogenic hazards. As soil is the source to almost all lives on earth and it is duty, the scientific community is developing ways to disseminate and communicate the most recent advancements to restore its health. Content of the book is designed in such a way that it provides a compressive information to the readers to restore the soil health that will ultimately help to improve the health of microbes, animals as well as plants that thrive in the soil and ultimately the quality of life of human being. This book helpsresearch scholars and teachers working in agriculture, horticulture, and environmental management by utilizing advances in microbiology and biotechnology. It is of interest to undergraduate and graduate students, teachers, researchers, environmentalists, agriculture and horticulture scientists, capacity builders, policy makers and all other stakeholders.

Advances and New Trends in Environmental Informatics 2023: Sustainable Digital Society (Progress in IS)

by Volker Wohlgemuth Dieter Kranzlmüller Maximilian Höb

This book is an outcome of the 37th International Conference EnviroInfo 2023, held at the Leibniz Supercomputing Centre (Munich, Germany), organized by the technical committee for Environmental Informatics of the German Informatics Society. It explores the fusion of information and communication technologies with environmental sustainability. As a flagship edition of the EnviroInfo conference series, it showcases the latest advancements in applied informatics and environmental informatics. With a focus on "Towards a Sustainable Digital Society," the conference presents innovative research on topics such as green computing, sustainable software engineering, and digital transformation. The proceedings cover essential subjects for shaping a greener future, including energy-efficient workloads, environmental management systems, legal frameworks, Earth observation, and geographical information systems. It also examines emerging technologies like robotics, AI, and reinforcement learning, highlighting their applications in environmental informatics. From citizen science to disaster risk modeling and sustainable resource management, the book explores the interdisciplinary nature of environmental informatics. It also addresses societal aspects, including its role in developing countries. This resource is essential for researchers, professionals, and policymakers seeking to leverage ICT for addressing environmental challenges and building a sustainable digital society.

Advances and Prospects of 3-d Metal-Based Anticancer Drug Candidates

by Farukh Arjmand Sartaj Tabassum Huzaifa Yasir Khan

This book reviews the potential of metallodrugs against different cancer. It summarizes the classification of metal-based anti-cancer drugs, their plausible biochemical and mechanistic pathways, combining drug strategies for hitting multiple therapeutic targets at the intracellular level, and advanced drug delivery strategies. The book covers the metallodrugs for the efficacious treatment of diverse cancerous strains and recent advances in drug delivery strategies that are used for developing these metal-based therapeutics as potent anticancer agents in vitro and in vivo. The book also covers different biophysical and analytical techniques for studying metal-ligand and metal-macromolecular interactions. The book further presents the recent examples of metallomics studies on the different types of cell death induced by metal-based anticancer drugs, especially on the three major forms of programmed cell death (PCD) in mammalian cells: apoptosis, autophagy, and regulated necrosis, alsocalled necroptosis. Lastly, the book explores the modulation of reactive oxygen species (ROS) by metallodrugs.

Advances in 3D Bioprinting (Series in Materials Science and Engineering)

by Roger J. Narayan

"3D bioprinting" refers to processes in which an additive manufacturing approach is used to create devices for medical applications. This volume considers exciting applications for 3D bioprinting, including its use in manufacturing artificial tissues, surgical models, and orthopedic implants.The book includes chapters from leaders in the field on 3D bioprinting of tissues and organs, biomedical applications of digital light processing, biomedical applications of nozzle-free pyro-electrohydrodynamic jet printing of buffer-free bioinks, additive manufacturing of surgical models, dental crowns, and orthopedic implants, 3D bioprinting of dry electrodes, and 3D bioprinting for regenerative medicine and disease modeling of the ocular surface.This is an accessible reference for students and researchers on current 3D bioprinting technology, providing helpful information on the important applications of this technology. It will be a useful resource to students, researchers, and practitioners in the rapidly growing global 3D bioprinting community.

Advances in Additive Manufacturing: Selected Contributions to the 2nd Advances in Additive Manufacturing Conference (AIAM' 2023), May 18–20, 2023, Hammamet, Tunisia (Lecture Notes in Mechanical Engineering)

by Tarek Mabrouki Habib Sahlaoui Haifa Sallem Farhat Ghanem Nourredine Benyahya

This book reports on research and developments in the field of 3D printing, with a special emphasis on methods to analyse the products of additive manufacturing, and optimize different steps of the manufacturing process. Gathering selected contributions to the 2nd Advances in Additive Manufacturing Conference (AIAM' 2023), held on Mai 18-20, 2023, in Hammamet, Tunisia, this book covers a variety of topics, including: analysis of microstructure and material behavior, numerical simulation and model techniques for optimization of manufacturing processes, machine learning for quality control and automated monitoring, among others. Offering a good balance of fundamental research and industrially relevant findings, this book provides researchers and professionals with a timely snapshot of and extensive information on current developments in the field and a source of inspiration for future research and collaboration.

Advances in Air Quality Research in Africa: Proceedings of the First International Conference on Air Quality in Africa (ICAQ'Africa 2022) (Advances in Science, Technology & Innovation)

by Abdelwahid Mellouki Khanneh Wadinga Fomba Bertrand Tchanche Fankam Daniel M. Westervelt Michael R. Giordano

This book presents the recent findings on air quality in Africa from the virtual event of the first International Conference on Air Quality in Africa (ICAQ 2022), providing a comprehensive overview on many subjects of air pollution that affect African society. It highlights research progress in the chemical and physical characterization of air pollutants, their related respiratory and non-respiratory health effects, measurements and monitoring of air pollutants using satellite remote sensing and modeling techniques, currently implemented abatement policies in different African countries, existing research and networking infrastructures, and novel tools for monitoring air quality. The advances in the development of local cost-effective air quality monitoring tools in Africa as well as the use of low-cost sensors in quantifying air quality levels are presented. This book is an enrichment for researchers, experts, and advocates of air quality, atmospheric chemistry and physics, satellite remote sensing applications, and policymakers in Africa.

Advances in Antiviral Research (Livestock Diseases and Management)

by Naveen Kumar Yashpal Singh Malik Shailly Tomar Sayeh Ezzikouri

This book illustrates advancements in the sophisticated tools and techniques for discovering and designing new antiviral drugs, identifying approved drugs against new and emerging viruses through large-scale computational virtual screening or drug repurposing approaches, and their evaluation in various in vitro and in vivo models. The chapters also cover the challenges associated with the emergence of antiviral drug resistance and possible ways to counter them. It discusses bioinformatics tools and software and computational approaches for the discovery of antivirals. The books also outline approaches for designing broad-spectrum antivirals effective against viruses by epigenetic- and epitranscriptomic-targeted reprogramming. Further, it provides vital details on the procedures for drug applications, clinical trials, and their regulations. Finally, the book provides a comprehensive yet representative description of advances in antiviral research protocols and methodologies suitablefor antiviral researchers at all career stages, including graduate and postgraduate students and policy-makers. ​

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