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Multimodal Management of Canine Osteoarthritis (Manson Ser.)
by Steven M. FoxMultimodal Management of Canine Osteoarthritis, Second Edition takes an evidence-based approach to the canine patient with osteoarthritis, pursuing the objective of the best available medicine by a variety of means: multiple drugs, agents, adjuncts and delivery methods. Appreciating that surgical intervention may initially be required, particularly for stabilizing a joint, the major focus in this work is the conservative management of osteoarthritis. A clear and visual approach is taken with the overlapping of two three-pointed triangles of management: medical and non-medical. The completely updated new edition offers a major new chapter on Regenerative Medicine in collaboration with Drs Sherman Canapp and Brittany Jean Carr. It is recommended for any small animal veterinary practitioner, as well as researchers and students of the RCVS CertAVP.
Multiple Sequence Alignments: Which Program Fits My Data?
by Theodor SperleaThis book is a practical guide for biologists who use multiple sequence alignments (MSAs) for their data analysis and are looking for a comprehensive overview of the many different programs. Despite their important role in data analysis, there is uncertainty among researchers about exactly how MSA programs work - not to mention how and why the different analyzes lead to different results. Which program is the right one for evaluating my data and how can I ensure that I have drawn all relevant findings from the alignments? This book offers helpful explanations and background information without requiring extensive bioinformatics knowledge and slowly introduces the reader to the topic.In the first part of the book, the possible fields of application as well as the formats that are usually produced by MSA programs are described in detail. The central algorithms as well as the internal processes of the most common MSA programs of the past and the present are also explained in an uncomplicated manner in greater detail. The second part of the book is a detailed, data-based comparison between MSA programs, which is intended to help you decide which program to use for your next alignment.
Multiple Sequenzalignments: Welches Programm passt zu meinen Daten?
by Theodor SperleaDieses Buch ist ein praktischer Ratgeber für Biologinnen und Biologen, die Multiple Sequenzalignments (MSAs) für ihre Datenanalysen verwenden und einen verständlichen Überblick über die vielen verschiedenen Programme suchen. Trotz ihres wichtigen Stellenwertes in der Datenanalyse herrscht Unsicherheit unter den Forschenden wie MSA-Programme genau funktionieren - ganz zu schweigen davon, wie und warum die unterschiedlichen Analysen zu verschiedenen Ergebnissen führen. Welches Programm ist für die Auswertung meiner Daten das richtige und wie kann ich sicherstellen, alle relevanten Erkenntnisse aus den Alignments gezogen zu haben? Dieses Buch bietet hilfreiche Erklärungen und Hintergründe ohne große bioinformatische Vorkenntnisse vorauszusetzen und führt die Leserinnen und Leser langsam in die Thematik ein.Im ersten Teil des Buches werden die möglichen Einsatzfelder wie auch die Formate, die üblicherweise von MSA-Programmen produziert werden, im Detail beschrieben. Ebenso werden auf unkomplizierte Weise die zentralen Algorithmen sowie die inneren Abläufe der gängigsten MSA-Programme der Vergangenheit und der Gegenwart in größerer Detailtiefe erklärt. Den zweiten Teil des Buches bildet ein ausführlicher datenbasierter Vergleich zwischen MSA-Programmen, der als Entscheidungshilfe für die Programmauswahl für dein nächstes Alignment dienen soll.
Multisensory Object Perception in the Primate Brain
by Marcus Johannes Naumer Jochen KaiserTraditionally, a large proportion of perceptual research has assumed a specialization of cortical regions for the processing of stimuli in a single sensory modality. Perception in everyday life, however, usually consists of inputs from multiple sensory channels. Recently the question of how the brain integrates multisensory information has become the focus of a growing number of neuroscientific investigations. This work has identified both multisensory integration regions and crossmodal influences in brain areas traditionally thought to be specific to one sensory modality. Furthermore, several factors have been identified that enhance integration such as spatio-temporal stimulus coincidence and semantic congruency. Multisensory Object Perception in the Primate Brain elucidates the mechanisms of multisensory integration of object-related information with a focus on the visual, auditory, and tactile sensory modalities. Evidence is presented in four sections: methodological considerations, audio-visual processing, visuo-tactile processing, and plasticity, and includes studies in both human and nonhuman primates at different levels of analysis. Studies range from intracranial electrophysiological recordings to non-invasive electro- or magnetoencephalography, functional magnetic resonance imaging, behavioral approaches, and computational modeling.
Multispecies Dialogues: Doing Philosophy with Animals, Children, the Sea and Others
by Eva MeijerIn Multispecies Dialogues Eva Meijer develops a new understanding of the concept ‘dialogue’, which includes embodied, material and spatial interaction. Meijer does not do this alone: each chapter of the book is devoted to a dialogue, or set of dialogues – with street dog Olli, a community of former lab mice, amphibian neighbours, the North Sea, and many other beings. Taking multispecies dialogues seriously is a way to do justice to more-than-human agency and to become more worldly in a time dominated by humans. Rethinking the model of the dialogue also opens up new ways of doing philosophy in multispecies world, which is urgently needed to address the ecological, political and philosophical problems of our time.
Multivariate Statistical Machine Learning Methods for Genomic Prediction
by José Crossa Osval Antonio Montesinos López Abelardo Montesinos LópezThis book is open access under a CC BY 4.0 licenseThis open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.
Mum Sees Rat: Independent Reading Pink 1A (Reading Champion #1)
by Jackie WalterReading Champion offers independent reading books for children to practise and reinforce their developing reading skills.Fantastic, original stories are accompanied by engaging artwork and a reading activity. Each book has been carefully graded so that it can be matched to a child's reading ability, encouraging reading for pleasure.Independent Reading Pink 1A stories are perfect for children aged 4+ who are reading at book band 1A (Pink) in classroom reading lessons.In this story, the pet rat has escaped and Mum keeps finding it everywhere!
Mummy Cat
by Lisa Brown Marcus EwertDeep within this maze of stone, a creature wakes up, all alone . . . Mummy Cat prowls his pyramid home, longing for his beloved owner. As he roams the tomb, lavish murals above his head display scenes of the cat with his young Egyptian queen, creating a story-within-a-story about the events of centuries past. Hidden hieroglyphs deepen the tale and are explained in an informative author's note. Marcus Ewert and Lisa Brown's smart, beautiful book is a marvel of sophisticated simplicity, infinitely engaging to examine in detail, and complete with a sweetly surprising plot twist sure to delight young cat-lovers and budding Egyptologists alike.
Mums and Mayhem: A Magic Garden Mystery (A Magic Garden Mystery #3)
by Amanda FlowerA famous fiddler has been kilt. A magic garden's left to wilt. Does Fiona Knox's father hold the guilt? Will florist Fiona's blood be spilt?World-famous fiddle player Barley McFee arrives in blustery Bellewick, Aberdeenshire, Scotland, for a grand homecoming concert organized by jeweler Bernice Brennan. Fiona Knox, owner of the Climbing Rose Flower Shop, is starting to regret volunteering to help with the concert. Bernice is an exacting taskmaster, and Fiona has enough tension dealing with her parents, who have traveled from Tennessee to visit Fi and her younger sister, Isla, and to reveal a secret about Fi's birth. But when Barley is found dead in his trailer during the concert's intermission, and his death is shockingly tied to Fiona's father, Fiona discovers there are more secrets surrounding her family than she realized.Much to the chagrin of handsome Neil Craig, Chief Inspector of the County Aberdeen Police, Fiona delves into the case to clear her father's name. To make matters worse, Fiona learns that Duncreigan, the magical garden that she inherited from her godfather, is dying. At some point during the concert, someone broke into the garden and cut the centuries-old climbing rose--the source of the garden's magic--from the standing stone.The stakes are higher than ever and Fiona could lose all that she's grown unless she's able to dispel this terrible curse and dig up the truth--fast.
Muncha! Muncha! Muncha!
by Candace FlemingAs Mr. McGreely works hard to make his beloved garden bountiful, he must contend with three pesky bunnies that hungrily come after what he has grown.
Munching, Crunching, Sniffing, and Snooping (DK Readers Level 2)
by Brian MosesMunching, crunching, sniffing, and snooping - meet lots of "nosy" animals and learn how they use their special snouts. You'll be amazed at what animals do with their mouths and noses in this Level 2 DK Reader! Packed with full-color photographs, lively illustrations, and engaging, age-appropriate stories to introduce young children to a life-long love of reading. These amazing stories are guaranteed to capture children's interest while developing their reading skills. Perfect for reading together! The playful images in this eBook are enhanced with entertaining animations and surprising sounds to bring this story to life.
Munching, Crunching, Sniffing, and Snooping (DK Readers Level 2)
by Brian MosesMunching, crunching, sniffing, and snooping - meet lots of "nosy" animals and learn how they use their special snouts. You'll be amazed at what animals do with their mouths and noses in this Level 2 DK Reader! Packed with full-color photographs, lively illustrations, and engaging, age-appropriate stories to introduce young children to a life-long love of reading. These amazing stories are guaranteed to capture children's interest while developing their reading skills. Perfect for reading together!
Mungo
by Rosalie FryThere comes a time when you've got to let them go free or they'll never learn to look after themselves," old Mrs. Moffatt warned Aunt Hilda. And that was the start of Richie's freedom to roam the wild Scottish coast near the hotel where they were living, for until then Aunt Hilda had been afraid to let him go anywhere alone. Soon Richie found a "special place"--a cliff hidden by overhanging heather, from which he could watch an inlet that he liked to think of as a secret bay. One day, as he lay on top of the cliff, Richie saw an alarmingly long creature stretching out into the sea like a reef of rocks--"like a kind of giant lizard with the longest neck in the world," thought Richie--a silly, friendly smile on its face. This was Mungo, last and gentlest of the ancient sea monsters. Soon Richie learned that Mungo liked to eat sea greens and potato crisps; more important, he noticed that a certain "clong" sound from across the water summoned Mungo out to sea, toward the island of Muckle Craig. In one of Rosalie K. Fry's most entertaining stories, Mungo eventually takes Richie on the greatest adventure of his life.
Murano Mice: Tales for Wise Children II
by May KolianderThe creatures in these tales are faced with challenges. They will have to rely on their resilience, inventiveness and the ability to relate to others to tackle what comes their way. Rebecca, the matron heading the Glassworks mice, is frantically searching for a misplaced will. She will need her daughter’s help to outwit crafty Micio, the alley cat, and retrieve the precious document before it is too late. Gloomy Daisy, an unconsolable dairy cow who has been deprived of her calves, ventures away from the pasture where her companions are peacefully grazing to enter the realm of the great auroch, thereby finding happiness. And what about Taco and Pico, the lab mice? Being made to run through mazes all day is no fun. The pair make a daring escape, but are in for a few surprises, among which learning that not all mice are white. Or Leonardo, a young fox who finds out at his expense that he would have done well to heed his mother’s warning. Going into the woods on one of the ‘Terrible Nights’ has dire consequences; it won’t be easy for him to put things right. There are many more creatures within the pages of this book – among which a bombastic tardigrade – just waiting to share their stories with you.
Murder Always Barks Twice (A Chatty Corgi Mystery #2)
by Jennifer HawkinsA charming tea room owner and her excitable talking corgi will need to work together to bring a killer to heel in this delightful cozy mystery. For ex-accountant Emma Reed and her beloved corgi, Oliver, opening Reed&’s Classic Tea & Cakes in the idyllic village of Trevena in Cornwall has been the fulfillment of a lifelong dream. Her cakes are popular, she has a host of wonderful new friends, and even a potential new romance. There&’s even time left over for plenty of long country walks with Oliver, who is not only the cutest corgi on record (at least to Emma), he happens to talk (at least to Emma). What could be better? How about being asked to help cater the local Daphne DuMaurier literary festival? But when the festival organizer is found dead and foul play is suspected, Emma, Oliver and their friends are plunged deep into a poisonous mix of village jealousy, family tension, money troubles, and secret love affairs. Emma quickly realizes it&’s up to her and her intrepid corgi to discover a canny killer whose bite is worse than their bark.
Murder Before Evensong: The instant no. 1 Sunday Times bestseller (Canon Clement Mystery)
by Reverend Richard ColesTHE INSTANTLY ICONIC NO. 1 BESTSELLER'Devotees of Midsomer Murders and Agatha Christie's Miss Marple stories will feel most at home here' Guardian'I've been waiting for a novel with vicars, rude old ladies, murder and sausage dogs... et voila!' Dawn French'Cosy crime with a cutting edge' Telegraph'Whodunnit fans can give praise and rejoice' Ian Rankin'Charming and funny' ObserverEven better than I knew it would be' India Knight'Quintessentially English' Sunday Express'An absolute joy' Adam Kay''Wry, tongue-in cheek and whimsical' Daily Mail'Glorious' Robert Webb 'Beautifully written, charming, funny, intelligent and mordant too' Sunday Times'Pitch perfect' Philip Pullman'A cunning whodunnit' Daily ExpressCanon Daniel Clement is Rector of Champton, where he lives alongside his widowed mother - opinionated, fearless, ever-so-slightly annoying Audrey - and his two dachshunds, Cosmo and Hilda.When Daniel announces a plan to install a lavatory in the church, the parish is suddenly (and unexpectedly) divided: as lines are drawn, long-buried secrets come dangerously close to destroying the apparent calm of the village.And then Anthony Bowness - cousin to Bernard de Floures, patron of Champton - is found dead at the back of the church. As the police moves in and the bodies start piling up, Daniel is the only one who can try and keep his community together... and catch a killer.
Murder Can Confuse Your Chihuahua (A Haunted Craft Fair Mystery #2)
by Rose PresseyThere&’s a killer in the picture . . . Celeste Cabot has a flair for painting—and a touch of paranormal talent too. She&’s just arrived to sell her artwork at a big craft fair in North Carolina, complete with rides, games, and deep-fried everything. But the sunny landscape takes on a darker hue when her Chihuahua, Van Gogh, leads her to the riverbank—and to a body that was definitely not part of her design. With help from a handsome fellow artist, Celeste sets out to draw the brazen killer onto her canvas. She&’ll need to balance the victim&’s past, a suspected love triangle, and a long-ago accident—and also consult with a medium and a spirit—to try to paint a murderous fiend into a corner . . . Includes tips and recipes! PRAISE FOR ROSE PRESSEY AND MURDER CAN MESS UP YOUR MASTERPIECE &“Plucky, self-employed heroine, cute pet, scary ghost, and two eligible suitors: everything a cozy needs.&”—Kirkus Reviews &“The paranormal twist adds a bit of flair to this quirky new series.&”—The Parkersburg News & Sentinel &“Absolutely delightful! A delightful mystery full of Southern charm.&” —New York Times Bestselling Author Jenn McKinlay
Murder Can Mess Up Your Masterpiece (A Haunted Craft Fair Mystery #1)
by Rose PresseyHaunted art is in the eye of the beholder . . . Artist Celeste Cabot welcomes the chance to show her paintings at a craft fair in her hometown of Gatlinburg, Tennessee, where she and her Chihuahua, Van Gogh, can park her vintage Shasta trailer and sell her creations, too. Unfortunately, her sales take a hit when a customer returns a painting, claiming it’s haunted. When a fellow vendor discovers images hidden in Celeste’s artwork—and a ghost pays her a late-night visit—she’s shocked to realize she has psychic abilities. After the grumpy manager of the craft fair is found with a knife in his neck, Celeste’s brushes with the paranormal may help fill in the picture—and make sure the wrong person doesn’t get framed . . . Praise for Rose Pressey and the Haunted Vintage Mysteries “Rose Pressey’s books are fun!”—Janet Evanovich “Chock full of ghosts, cats possessed by spirits, a handsome police officer boyfriend, and tips on the afterlife and vintage shopping.” —Kirkus Reviews “An appealing protagonist who is as sweet as a Southern accent.” —Library Journal “A sheer delight.”—Kate Carlisle
Murder Go Round (A Witch City Mystery #4)
by Carol J. PerryAn antique carousel horse sends Salem, Massachusetts, into a spin in this eerie murder mystery: &“Highly original and great fun.&” —Carolyn Hart, New York Times-bestselling author of Ghost Ups Her Game Lee Barrett has agreed to attend a storage auction with Aunt Ibby—even though she suspects the forgotten rooms will yield more junk than treasure. Her skepticism vanishes once the two win an overlooked locker and uncover a trove of beautiful curiosities, including a stunning wooden carousel horse with gentle eyes and fading paint. But just before Lee leaves the fairground relic at a local repair shop, the sight of a silver samovar awakens her psychic abilities and conjures visions of murder. Lee prays the intrusive ESP episode was just a glimpse into the past—until her policeman boyfriend reports a dead man outside the shop. Apparently, the unknown victim had been hot on Lee&’s trail since the auction. And with the horse found dismantled, it looks like he was up to no good. What&’s the story behind the antique equine, and could a strange bubblegum-chewing woman with fiery hair have something to do with it all? Guided by her gift and O&’Ryan, her wise tabby cat, Lee&’s set on catching the murderer . . . before she&’s sent on the darkest ride of her life. Praise for The Witch City Mysteries &“Perfectly relaxing and readable.&”– Kirkus Reviews &“This rewarding paranormal cozy series debut will have Victoria Laurie fans lining up to follow.&” —Library Journal &“Keeps readers guessing until the very twisted and eerie end.&” —RT Book Reviews
Murder Most Beastly (Dog Lovers #8)
by Melissa ClearyCRIME IN CAPTIVITY The only zoo that Jackie usually has to deal with is her Friday film class. But when her friend Marcella goes undercover at the Palmer Wildlife Habitat to investigate alleged abuses, the bizarre death of a zookeeper turns a feature story into a front-page scandal... and Jackie can’t help but get involved. Because after dealing extensively with the darker side of the human species, Jackie knows that not all the so-called animals are behind bars...
Murder Most Feline: Cunning Tales of Cats and Crime
by Ed Gorman Larry Segriff Martin H. GreenbergWHEN LAW MEETS PAW The result is this delightful anthology of sixteen original courtroom tales by top-notch mystery writers. Always dignified, cats are quick to mete out their own justice with a claw or a bite, and so it is only natural that we find them in a variety of roles in these feline mysteries. Cats take the stand in their defense to pounce on criminals, provide evidence, and turn the legal system on its collective ear—all in the name of justice. From a private eye who goes to bat for a cat's inheritance to a common mouser who turns out to be quite a bit more during a high-profile murder trial, these tales of crime are as crafty and cunning as cats themselves—and just as entertaining. In a section of Author Biographies after the primary content readers are given the opportunity to discover additional stories and novels by the authors they have particularly liked. Authors include: Ann Barrett, Gary A. Braunbeck, Richard Chizmar, Barry Hoffman, Bill Crider, Janet Dawson, Parnell Hall, Tracy Knight, Shirley R. Murphy, Dulcy Brainard, Jon L. Breen, Matthew J. Costello, Mat Coward, Catherine Dain, Jan Grape, Jeremiah Healy, Dick Lochte
Murder Most Finicky (A Pawsitively Organic Mystery #4)
by Liz MugaveroA baker opens up a new pastry shop exclusively for pets—but has to do a sleuthing job on the side when a chef turns up dead . . . The dog days of summer have arrived in the small town of Frog Ledge, Connecticut, and business is booming for Kristan &“Stan&” Connor. Her Pawsitively Organic pet food has even caught the attention of celebrity pastry chef Sheldon Allyn, who helps Stan open a fancy pet pastry shop in Frog Ledge. A partnership is born, and Sheldon invites Stan to Newport, Rhode Island, for an appreciation weekend he&’s hosting for all his independent chefs. But the gourmet getaway turns sour when one of the chefs turns up dead, and a second one goes missing . . . As Stan tries to figure out who had a recipe for murder, the pool of suspects expands. And if she can&’t sniff out the culprit soon, this killer may just serve up a second helping of murder . . . Includes Gourmet Pet Food Recipes!
Murder Past Due (Cat in the Stacks Mystery #1)
by Miranda JamesTHE FIRST BOOK IN THE NEW YORK TIMES BESTSELLING CAT IN THE STACKS MYSTERY SERIES which Introduces the appealing, crime-solving duo: genial librarian Charlie Harris, and his rescue cat, gentle giant, Diesel.No good library is complete without a great cat…and an even better detective. Home for the first time in years, librarian Charlie Harris and his walking companion, Maine Coon cat, Diesel, have become familiar sights on the streets of small town Athena, Mississippi. All Charlie wants to do is devote himself to the books in his care, but those plans are shelved when he finds himself enmeshed in the claws of a true murder-mystery…Charlie’s absolutely dreadful old classmate-turned-celebrated author, Godfrey Priest, has also descended upon Athena. Fame certainly hasn’t changed Godfrey; if anything, he’s more obnoxious than he was when they were young. In one day, he’s put one man in the hospital; before the next dawn, he’s dead! Charlie and Diesel must investigate a seemingly endless supply of motivated suspects to trap the real killer before an innocent is falsely purr-secuted!
Murder Unleashed (Jack and Jamie Mystery #2)
by Lee Charles KelleyIn this delightful second book in our wonderful new series created by veteran dog trainer Lee Charles Kelley, a clever kennel owner and his endearing canine companions once again work to solve baffling mysteries. Ex-New York cop turned kennel owner Jack Field is perfectly happy training dogs and living the simple life in the rustic woods of Maine. But once again, he and his girlfriend Jamie, the smart and sexy local coroner, are dragged into a mystery of remarkable proportions. When a prominent local judge is found dead in his car, his throat ripped open, with a ferocious boxer locked inside the car with him, all fingers point to the dog as the killer. But when Jack is called in to handle the growling beast, he soon realizes that this frightened boxer is no killer, and he's determined to find the real culprit before his doggy friend is put down for the judge's death. Soon, Jack and Jamie are immersed in a scandal that reaches throughout the town, involving the brazen local marijuana dealer and his delightful brood of ten beagles, Jamie's shady drug addicted ex-husband, twisted family secrets, and an outrageous attempt at blackmail. Full of wit and originality.
Murder With a View: A House-Flipper Mystery (A House-Flipper Mystery #3)
by Diane KellyMurder With a View is the third book in the delightful cozy mystery series from Diane Kelly set in Nashville, Tennessee—where the real estate market is to die for…A DREAM PROPERTYCarpenter Whitney Whitaker, her cousin Buck, and guard-cat Sawdust just scored a hot property near downtown Nashville in a tax sale. While the Music City Motor Court might not be much to look at now, the two plan to transform the motel’s twelve units into six one-bedroom condominiums with popular mid-century styling. But surprises await when Whitney discovers a squatter living in Room 9 and her cat Sawdust uncovers a body in the bed next door.A LIVING NIGHTMAREThe murder victim is none other than Beckett Morgan, an up-and-coming country-western singing sensation who’s taken Nashville by storm with his number-one hit “Party in the Pasture.” Beckett’s left a long trail of broken promises and broken hearts, and the list of suspects seems endless. So does the line of female fans intent on halting the flip and turning the construction site into a shrine for the deceased star. If Whitney and Buck don’t help Detective Collin Flynn nail the killer, they’ll never be able to clear out the star-obsessed groupies, complete the remodel, and recoup their investment. But just who silenced the singer and why?