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Androgen-Responsive Genes in Prostate Cancer: Regulation, Function and Clinical Applications
by Zhou WangAndrogens and androgen receptors (AR) play critical roles in the development and progression of prostate cancer, the most frequently diagnosed cancer and second leading cause of cancer death in US males. AR is an androgen-dependent DNA-binding transcription factor that regulates the expression of androgen-responsive genes. Identification and characterization of androgen-responsive genes provide insights into the cellular mechanisms of androgen action and may lead to new approaches in diagnosis, prognosis, prevention and/or treatment of prostate cancer. This volume provides critical information from well respected experts in the field. Some of the exciting topics include the new understanding of mechanisms underlining the regulation of androgen-responsive gene expression, and functions of various androgen-responsive genes in biological processes essential in carcinogenesis including cell growth, angiogenesis, and epithelial-to-mesenchyme transition (EMT). Other important aspects addressed are the current and potential clinic applications of knowledge on androgen-responsive gene regulation and function. This book is intended for researchers, scientists, faculty, and advanced graduate students with an interest in androgen action and prostate cancer.
Andrologie: Grundlagen und Klinik der reproduktiven Gesundheit des Mannes (Springer Reference Medizin)
by Eberhard Nieschlag Hermann M. Behre Sabine Kliesch Susan NieschlagDas Buch gibt einen vollständigen Überblick über die zentralen Themen der Andrologie: Infertilität, Hypogonadismus, Kontrazeption und erektile Dysfunktion. Es enthält detaillierte Informationen u. a. zur klinischen Praxis der Paarbehandlung, zu modernen Verfahren der assistierten Fertilisation, psychologischen Faktoren der Infertilität sowie dem männlichen Beitrag zur Kontrazeption. Zusätzlich werden die relevanten naturwissenschaftlichen Grundlagen abgedeckt. Die 3. Auflage wurde auf den neuesten Stand der Forschung gebracht.
Andrology: Male Reproductive Health and Dysfunction
by Eberhard Nieschlag Hermann M. Behre Sabine Kliesch Susan NieschlagThe successful book of andrology now in a new edition! This book gives a complete, interdisciplinary overview of the central topics of andrology, infertility, hypogonadism, contraception and erectile dysfunction. It contains detailed information on the clinical practice of couple treatment, andrology-relevant gynecology and modern methods of assisted fertilization, psychological factors of infertility, endocrinology and reproductive functions of the aging man as well as on an important sub-area of andrology, the male contribution to contraception. In addition, the relevant scientific foundations (including molecular biology and genetics) are also covered. Completely revised and updated according to the latest scientific research, the new edition represents a reference for andrology, which no doctor who deals with the topic can miss. For andrologists, practitioners and residents, urologists, dermatologists and internists who deal with the area of andrology and male reproductive medicine.
Andrology: Male Reproductive Health and Dysfunction
by Eberhard Nieschlag Hermann M. Behre Susan NieschlagThis is the 3rd, totally revised edition of a well-known textbook that continues to represent the gold standard in the literature on clinical andrology. It examines in depth all aspects of male reproductive health, encompassing the basic physiology of male reproductive function and a wide range of disorders. Each of the chapters is written by outstanding experts in the field. Among the topics covered are: Testicular function, sperm maturation and fertilization, diagnostic procedures, infertility, primary and secondary hypogonadism, late-onset hypogonadism, erectile dysfunction, genetic disorders, environmental influences, psychology and sexual medicine, testosterone therapy, assisted reproduction: TESE and ICSI, cryopreservation, male contraception and ethics in andrology. This volume will serve as a textbook for the newcomer to andrology, while providing the experienced physician with a valuable reference work. It will appeal to all who are concerned with male reproductive health.
Anesthesia and Perioperative Care for Aortic Surgery
by Balachundhar Subramaniam Kathirvel Subramaniam Kyung W. ParkThis book is the first of its kind - a comprehensive reference for anesthesia and perioperative clinicians involved in aortic surgery. With a primary focus on anesthesia for various aortic surgical procedures, including endovascular aortic surgery, the title also provides expanded coverage of CNS monitoring and protection, intraoperative transesophageal echocardiography, renal and spinal cord protection during surgery, management of aortic trauma, and postoperative care. Written by top cardiac anesthesiologists, surgeons, and intensivists, this indispensable reference provides everything you need to know about the burgeoning field of aortic surgery in one handy volume.
Anesthesia and Perioperative Care of the High-Risk Patient
by Ian McConachie MB ChB FRCA FRCPCThe fully updated third edition of this popular handbook provides a concise summary of perioperative management of high-risk surgical patients. Written by an international group of senior clinicians, chapters retain the practical nature of previous editions, with concise text in a bulleted format offering rapid access to key facts and advice. Several new chapters cover topics including: anesthetic mortality; cardiopulmonary exercise testing; perioperative optimization; obstructive sleep apnea and obesity hypoventilation syndrome; smoking, alcohol and recreational drug abuse; intraoperative ventilatory management; the role of simulation in managing the high-risk patient; anesthesia, surgery and palliative care; anesthesia and cancer surgery; neurotrauma and other high-risk neuro cases; anesthesia for end-stage renal and liver disease; and transplant patients. Essential reading for trainee anesthesiologists managing seriously ill patients during surgery or studying for postgraduate examinations, this is also a valuable refresher for anesthesiologists and intensivists looking for an update on the latest evidence-based care.
The Anesthesia Fact Book
by Frank SweenyStudies have shown that anesthesia regularly evokes more fear and anxiety for patients than the surgery for which it is being given. Yet despite this fact, most patients meet with their anesthesiologist for only about five minutes before surgery. The resulting unanswered questions and unresolved anxieties about anesthesia can unnecessarily weaken a patient both as he enters the operating room and in his recovery. Putting control back in the hands of the patient, The Anesthesia Fact Book reveals how various kinds of anesthesia work, answers the most common questions and concerns about the process, and provides information and strategies for achieving the safest, most comfortable, and least stressful anesthesia and surgery possible.
The Anesthesia Fact Book
by Frank SweenyStudies have shown that anesthesia regularly evokes more fear and anxiety for patients than the surgery for which it is being given. Yet despite this fact, most patients meet with their anesthesiologist for only about five minutes before surgery. The resulting unanswered questions and unresolved anxieties about anesthesia can unnecessarily weaken a patient both as he enters the operating room and in his recovery. Putting control back in the hands of the patient, The Anesthesia Fact Book reveals how various kinds of anesthesia work, answers the most common questions and concerns about the process, and provides information and strategies for achieving the safest, most comfortable, and least stressful anesthesia and surgery possible.
Anesthesiology and Otolaryngology
by Adam I. Levine Samuel Demaria Jr. Satish GovindarajTo an unusual degree, the shared "working space" of otolaryngologists and anesthesiologists means that issues important to one are important to the other. Anesthesiology and Otolaryngology is the first book to address the closely overlapping information needs of both groups of specialists. It is collaboratively written and edited by anesthesiologists and otolaryngologists, and the chapters are carefully designed to insure maximal relevance to members of both specialties. The heart of the book consists of chapters on managing patients during the full range of otolaryngologic procedures. These chapters are structured chronologically, and otolaryngologic and anesthesiologic perspectives are systematically presented for each operative stage. Foundational topics such as gross and radiographic anatomy, physiology, and pharmacology are covered. The book includes a unique chapter on oxygen delivery systems that serves as a comprehensive review for anesthesiologists and an overview for the otolaryngologist. Special topics addressed include acute and chronic pain management, and the logistics of managing an office-based surgical practice. · "All-in-one" reference for otolaryngologists and otolaryngologic anesthesiologists · Surgical and anesthesiologic perspectives marshaled for pre-operative, intraoperative, and postoperative periods · Pearls and Insights at end of chapters · Organized by surgical region · Special challenges of difficult airway and of pediatric otolaryngologic procedures addressed
The Angel and the Assassin: The Tiny Brain Cell That Changed the Course of Medicine
by Donna Jackson NakazawaA thrilling story of scientific detective work and medical potential that illuminates the newly understood role of microglia—an elusive type of brain cell that is vitally relevant to our everyday lives. &“The rarest of books: a combination of page-turning discovery and remarkably readable science journalism.&”—Mark Hyman, MD, #1 New York Times bestselling author of Food: What the Heck Should I Eat? Until recently, microglia were thought to be merely the brain&’s housekeepers, helpfully removing damaged cells. But a recent groundbreaking discovery revealed them to be capable of terrifying Jekyll and Hyde behavior. When triggered—and anything that stirs up the immune system in the body can activate microglia—they can morph into destroyers, impacting a wide range of issues from memory problems and anxiety to depression and Alzheimer&’s. Under the right circumstances, however, microglia can be coaxed back into being angelic healers, able to repair the brain in ways that help alleviate symptoms and hold the promise to one day prevent disease. A fascinating behind-the-scenes account of this cutting-edge science, The Angel and the Assassin also explores the medical implications of these game-changing discoveries. Award-winning journalist Donna Jackson Nakazawa began her investigation with a personal interest—when diagnosed with an autoimmune disorder years ago, she was convinced there was something physical going on in her brain as well as her body, though no doctor she consulted could explain how the two could be interacting in this way. With the compassion born of her own experience, she follows practitioners and patients on the front lines of treatments that help to &“reboot&” microglia—from neurofeedback and intermittent fasting to transcranial magnetic stimulation and gamma light flicker therapy. She witnesses patients finding significant relief from pressing symptoms—and at least one stunning recovery—offering new hope to the tens of millions who suffer from mental, cognitive, and physical health issues. Proving once and for all the biological basis for the mind-body connection, the discovery of the true role of microglia stands to rewrite psychiatric and medical texts as we know them. Hailed as &“riveting,&” &“stunning,&” and &“visionary,&” The Angel and the Assassin offers us a radically reconceived picture of human health and promises to change everything we thought we knew about how to heal ourselves.
Angel Blue (Spy High Series 2, Book #2)
by A. J. ButcherLori Angel is a graduate of the Deveraux College, the highly secret school for teenage spies. Until now she's been posted on the coast, doing a whole lot of surfing and partying. But then a fellow graduate turns up at her apartment. Dead. Stashed in his rucksack are a series of clues that will lead Lori into the most dangerous situation of her life. And into conflict with a secret society, every member of which is supposed to be dead. Lori Angel is the new spy novel from the author of the brilliant Edward Red. It's an everyday story of rad-surfing, cool parties and body-swapping megalomaniacs trying to destroy humanity.
The Angel By My Side: The True Story Of A Dog Who Saved A Man... And A Man Who Saved A Dog
by Mike Lingenfelter David FreiMike Lingenfelter was ready for his life to be over. Two serious heart attacks and open-heart surgery had taken away most of the good things that he had in his life. He just didn't care anymore. His doctors still held out hope for him, however, and they kept trying to find ways to motivate him to get out of the house and exercise. Their vision was that an energetic dog on a leash might do that for Mike. And so it was that this golden retriever named Dakota, who had been rescued from death himself, came to help Mike with his rehabilitative therapy. Their relationship wasn't supposed to be anything too profound or metaphysical or scientific, but as it turns out, at the other end of the leash was much more than a dog. Dakota gave Mike back his dignity, his pride, and his life. Early on, it became evident to Mike that this wonderful 98-pound, red-haired, four-legged angel had a special gift: Dakota was a spirit guide, and it was Mike's duty to share him and the power of the human-animal bond. Dakota continually helped make miracles happen, for Mike and for others. But ultimately, as part of that journey, one more miracle was needed, as Dakota fought a courageous and dignified battle for his own life.
The Angel by My Side: The True Story Of A Dog Who Saved A Man... And A Man Who Saved A Dog
by Mike Lingenfelter David FreiIt was 1995, and Mike Lingenfelter was ready for his life to be over. Two serious heart attacks and open-heart surgery had taken away most of the good things that he had in his life. However, his doctors still held out hope for him, and they were trying to find ways to motivate him to get out of the house and exercise. Their vision was that an energetic dog on a leash might do that for Mike. And so it was that this golden retriever named Dakota, who had been rescued from death himself, came to help Mike with his rehabilitative therapy. Eventually, Dakota became Mike’s protector and his best friend, saving Mike’s life several times after somehow learning how to alert Mike of oncoming heart crises. Dakota gave Mike back his dignity, his pride, and his life. Early on, it became evident to Mike that this wonderful 98-pound, red-haired, four-legged angel had a special gift: Dakota was a spirit guide, and it was Mike’s duty to share him and the power of the human-animal bond. Ultimately, as part of that journey, one more miracle was needed, as Dakota fought a courageous and dignified battle for his own life.
An Angel Changed my Life
by Theresa CheungAngel expert Theresa Cheung is back with a new collection of inspiring true stories about how our guardian angels can offer help, protection and direction in times of trouble and, by so doing, transform our lives forever. An Angel Changed My Life brings together a fascinating anthology of ordinary people's extraordinary experiences where angelic intervention has inspired them to turn their lives around. Uplifting, true-life accounts of miraculous healing and guidance include stories of near-death experiences, such as the teenager who found himself unaccountably brought to dry land after almost drowning; the grandmother who discovered superhuman strength when her grandchild faced mortal danger, and the grieving widow who found comfort, support and purpose from an angel presence. These stories bring us a much-needed tonic in a troubled world and show us how angels can bring a sense of wonder and gratitude to our lives, and give us a meaning and purpose we never knew we had.
Angel Chatter: Heavenly Guidance and Earthly Practice to Connect with Angels
by Christine AlexandriaWhatever faith we personally subscribe to, angels cross those boundaries and find their way into our lives. They remind us that we are not alone; that we are all guided and protected from another world. In her new informative, quirky, and practical guide, angel intuitive and award-winning author Christine Alexandria shares her profound gifts and vast knowledge of angels.Christine details how to strengthen our connection and become empowered by the fourteen archangels with whom she chats. Chapters include the therapeutic role of each angel, the chakra system and crystals affiliated with them, guided meditations, and more. Angel Chatter enables people from all traditions and faith backgrounds to access the wisdom, joy, and power of Christine’s “haloed gang.” The angels “will flock to assist us”—this is their simple yet solemn promise.
Angel Detox: Taking Your Life To A Higher Level Through Releasing Emotional, Physical, And Energetic Toxins
by Doreen Virtue Robert ReevesDetoxing with the help of your angels is a gentle way to release impurities from your body, fatigue, and addictions. Doreen Virtue and naturopath Robert Reeves teach you simple steps to increase your energy and mental focus, banish bloating, feel and look more youthful, and regain your sense of personal power. Rid your life of physical toxins, as well as negative emotions and energies. <P><P>Angel Detox guides you step-by-step on how to detox your diet, lifestyle, and relationships. You'll learn how to reduce or eliminate cravings for unhealthful food and substances, feel motivated, and enjoy wellness in all areas of your life. This book also includes 7-Day Detox Plans for those wanting to quit smoking or drinking, or to flush out environmental pollution.
Angel Dreams: Healing And Guidance From Your Dreams
by Doreen Virtue Melissa VirtueDreams are gateways to other worlds, times, and planes of existence. They are sacred portals through which we receive powerful messages from Source, often in the form of symbols brought to us by our dream guide and the angels. <P><P>In this book, Doreen Virtue and Melissa Virtue discuss where dreams come from, how to interpret them, what role angels play, and whom to call upon for guidance. You'll gain tools to enhance your dreamtime journeys, including techniques for creating your own dreams and improving your recall upon awakening. In addition, you'll learn to identify the different types of dreams by reading personal stories and interpretations that will help you decode your dream messages.
Angel Energy
by John Randolph PriceThe natural expression of the angels is Truth. If we deny the truth, we repress the energy of the angels. But when we fully accept the eternal verities of life, the angels go to work to bring everything up to the divine standard....Within each one of us dwell the twenty-two angels, centers of Living Energy that provide us with all we need to sustain us on our journey through life. They await only our readiness.However, the angels require our assistance to manifest changes in our lives. They are able to free us from disease and death, loneliness and unfulfillment, lack and limitation only when we free them. And so the author of the bestselling The Angels Within Us has written this book to help us set free the positive vibrations of these inner archetypes and their "nothing-is-impossible" energy.Through meditations, affirmations, exercises, dialogues with the twenty-two angels, and true stories of the miracles and transformations wrought by them, he helps us liberate the power of the Divine within so that we can: * Awaken our higher consciousness* Heal the past* Communicate with angels awake and dreaming* Find our right livelihood* Enjoy prosperity* Open ourselves to physical healing* Find fulfillment in our relationships* Surrender to unconditional love* And much moreOur angels are the very law of our being. This remarkable book helps us to connect and flow with their universal rhythm of wholeness, to become who and what we really are.From the Trade Paperback edition.
The Angel Experiment: A 21-Day Magical Adventure to Heal Your Life
by Corin GrilloDOWN-TO-EARTH SPIRITUAL WISDOM FROM THE ANGELS TO HEAL YOUR LIFE A mind-blowing miracle from the angels saved Corin Grillo&’s life, cured her of lifelong depression, and awakened her spiritual gifts. She now teaches others all over the world how to awaken their intuition, heal illness and addiction, create financial abundance, and discover their true purpose by working with the divine. IN THIS 21-DAY ADVENTURE, YOU WILL LEARN: • A powerful way to talk to angels so they can hear you and help you • How to hear, see, and feel the angels in your life • Which specific archangels to call upon for your unique needs • 21 daily angel invocations to help you manifest miracles • 21 healing meditations to detox your heart, mind, body, and soul Try The Angel Experiment, and you&’ll discover firsthand that miracles are real, there is no such thing as coincidence, and a mighty team of angels always has your back.
An Angel Healed Me
by Theresa CheungTheresa Cheung in an expert in the field of angels and divine healing. This, her latest collection of amazing true stories, focuses on the physical and emotional help people have experienced from unexplained or ethereal sources at times when they have been at their most vulnerable. With chapters such as 'Manifest a Miracle' and 'An Angel at My Bedside', the book tells of remarkable incidents where angels have appeared in hospital wards, at difficult births, during near-death experiences, and when someone actually dies, easing their journey from the corporeal to the spirit world. The common thread running through all these miraculous stories of healing from the inside out is that every angelic encounter provided the recipient with a strength, courage and power they never knew they had.
Angel Inspiration: Together, Humans And Angels Have The Power To Change The World
by Diana CooperHealer and spiritualist Diana Cooper offers her wisdom on how, together, humans and angels have the power to change the world. We are only now opening up to the presence of angels and their ability to guide us. Diana Cooper introduces us to the importance of them in our lives by drawing on countless stories of people who have had their own lives changed by the miraculous assistance of angels. These incredible accounts prove what a difference the divine messengers can make and are an inspiration to us all. Everyone has their own guardian angel, there to help and protect whenever possible. Few of us yet understand, however, the healing and support these angels can bring us and how to invoke their help. Diana Cooper introduces us to the whole hierarchy of angels and the special powers that we can call upon. With exercises and lessons to encourage your angelic presences, Angel Inspiration not only brings you closer to your angel but helps change other people's lives too.
Angel Inspiration: Together, Humans And Angels Have The Power To Change The World
by Diana CooperHealer and spiritualist Diana Cooper offers her wisdom on how, together, humans and angels have the power to change the world. We are only now opening up to the presence of angels and their ability to guide us. Diana Cooper introduces us to the importance of them in our lives by drawing on countless stories of people who have had their own lives changed by the miraculous assistance of angels. These incredible accounts prove what a difference the divine messengers can make and are an inspiration to us all. Everyone has their own guardian angel, there to help and protect whenever possible. Few of us yet understand, however, the healing and support these angels can bring us and how to invoke their help. Diana Cooper introduces us to the whole hierarchy of angels and the special powers that we can call upon. With exercises and lessons to encourage your angelic presences, Angel Inspiration not only brings you closer to your angel but helps change other people's lives too.
Angel Kids: Enchanting Stories Of True-life Guardian Angels And Sixth Sense Abilities In Children
by Jacky NewcombThis delightful book reveals the amazing encounters that children have with their guardian angels and loved ones on the Other Side, as well as fascinating insights into the lives of psychic children . . . and the parents who have to cope with this phenomenon. As you read, you’ll discover: • Grandparents who regularly visit their grandkids—from the Other Side! • Kids with extraordinary abilities, including mind-reading and the power to move objects with their thoughts alone • Young children who remember a life before they were born • The mother who lost a son who was later reborn as her grandson • The thousands of brilliant children whom the authorities have labeled as "learning disabled." Thousands of children the world over are being born with enhanced sixth-sense abilities. Psychic kids are the new "normal"!
Angel Medicine: How To Heal The Body And Mind With The Help Of The Angels
by Doreen VirtuePart spiritual adventure story and part reference book. Angel Medicine is a three-part work that relates the exciting story of Doreen Virtue's recovery of memories of Atlantian healing methods along with messages from the Egyptian and Greek prophet and deity Hermes and the angels. The second and third parts of the book reveal the scientific studies, case studies, methods, and charts supporting the importance of love and light in healing.
Angel Miracles: Inspirational True Stories of Heavenly Help
by Brad SteigerA near collision while driving. Recovery from a serious illness. Escaping an accident without a scratch. Everyone has had a moment when they knew someone up above was looking out for them down below. Some things are just unexplainable. Sometimes it has to be left to one's Guardian Angel. This book is a collection of stories that shine with hope and true inspiration. Compiled by Brad Steiger and Sherry Hansen Steiger, it celebrates the beauty of mysterious miracles that can only be attributed to those divine helpers. You will be astonished by these remarkably true stories of angelic intervention.