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Machine Learning for Econometrics and Related Topics (Studies in Systems, Decision and Control #508)

by Vladik Kreinovich Songsak Sriboonchitta Woraphon Yamaka

In the last decades, machine learning techniques – especially techniques of deep learning – led to numerous successes in many application areas, including economics. The use of machine learning in economics is the main focus of this book; however, the book also describes the use of more traditional econometric techniques. Applications include practically all major sectors of economics: agriculture, health (including the impact of Covid-19), manufacturing, trade, transportation, etc. Several papers analyze the effect of age, education, and gender on economy – and, more generally, issues of fairness and discrimination.We hope that this volume will:help practitioners to become better knowledgeable of the state-of-the-art econometric techniques, especially techniques of machine learning,and help researchers to further develop these important research directions. We want to thank all the authors for their contributions and all anonymous referees for their thorough analysis and helpful comments.

Machine Learning for Email: Spam Filtering and Priority Inbox

by John Myles White Drew Conway

If you’re an experienced programmer willing to crunch data, this concise guide will show you how to use machine learning to work with email. You’ll learn how to write algorithms that automatically sort and redirect email based on statistical patterns. Authors Drew Conway and John Myles White approach the process in a practical fashion, using a case-study driven approach rather than a traditional math-heavy presentation.This book also includes a short tutorial on using the popular R language to manipulate and analyze data. You’ll get clear examples for analyzing sample data and writing machine learning programs with R.Mine email content with R functions, using a collection of sample filesAnalyze the data and use the results to write a Bayesian spam classifierRank email by importance, using factors such as thread activityUse your email ranking analysis to write a priority inbox programTest your classifier and priority inbox with a separate email sample set

Machine Learning for Engineers: Introduction to Physics-Informed, Explainable Learning Methods for AI in Engineering Applications

by Marcus J. Neuer

Machine learning and artificial intelligence are ubiquitous terms for improving technical processes. However, practical implementation in real-world problems is often difficult and complex. This textbook explains learning methods based on analytical concepts in conjunction with complete programming examples in Python, always referring to real technical application scenarios. It demonstrates the use of physics-informed learning strategies, the incorporation of uncertainty into modeling, and the development of explainable, trustworthy artificial intelligence with the help of specialized databases. Therefore, this textbook is aimed at students of engineering, natural science, medicine, and business administration as well as practitioners from industry (especially data scientists), developers of expert databases, and software developers.

Machine Learning for Environmental Noise Classification in Smart Cities (Synthesis Lectures on Engineering, Science, and Technology)

by Ali Othman Albaji

We present a Machine Learning (ML) approach to monitoring and classifying noise pollution. Both methods of monitoring and classification have been proven successful. MATLAB and Python code was generated to monitor all types of noise pollution from the collected data, while ML was trained to classify these data. ML algorithms showed promising performance in monitoring the different sound classes such as highways, railways, trains and birds, airports and many more. It is observed that all the data obtained by both methods can be used to control noise pollution levels and for data analytics. They can help decision making and policy making by stakeholders such as municipalities, housing authorities and urban planners in smart cities. The findings indicate that ML can be used effectively in monitoring and measurement. Improvements can be obtained by enhancing the data collection methods. The intention is to develop more ML platforms from which to construct a less noisy. The second objective of this study was to visualize and analyze the data of 18 types of noise pollution that have been collected from 16 different locations in Malaysia. All the collected data were stored in Tableau software. Through the use of both qualitative and quantitative measurements, the data collected for this project was then combined to create a noise map database that can help smart cities make informed decisions.

Machine Learning for Factor Investing: Python Version (Chapman and Hall/CRC Financial Mathematics Series)

by Tony Guida Guillaume Coqueret

Machine learning (ML) is progressively reshaping the fields of quantitative finance and algorithmic trading. ML tools are increasingly adopted by hedge funds and asset managers, notably for alpha signal generation and stocks selection. The technicality of the subject can make it hard for non-specialists to join the bandwagon, as the jargon and coding requirements may seem out-of-reach. Machine learning for factor investing: Python version bridges this gap. It provides a comprehensive tour of modern ML-based investment strategies that rely on firm characteristics. The book covers a wide array of subjects which range from economic rationales to rigorous portfolio back-testing and encompass both data processing and model interpretability. Common supervised learning algorithms such as tree models and neural networks are explained in the context of style investing and the reader can also dig into more complex techniques like autoencoder asset returns, Bayesian additive trees and causal models. All topics are illustrated with self-contained Python code samples and snippets that are applied to a large public dataset that contains over 90 predictors. The material, along with the content of the book, is available online so that readers can reproduce and enhance the examples at their convenience. If you have even a basic knowledge of quantitative finance, this combination of theoretical concepts and practical illustrations will help you learn quickly and deepen your financial and technical expertise.

Machine Learning for Healthcare: Handling and Managing Data

by Rashmi Agrawal, Jyotir Moy Chatterjee, Abhishek Kumar, Pramod Singh Rathore and Dac-Nhuong Le

Machine Learning for Healthcare: Handling and Managing Data provides in-depth information about handling and managing healthcare data through machine learning methods. This book expresses the long-standing challenges in healthcare informatics and provides rational explanations of how to deal with them. Machine Learning for Healthcare: Handling and Managing Data provides techniques on how to apply machine learning within your organization and evaluate the efficacy, suitability, and efficiency of machine learning applications. These are illustrated in a case study which examines how chronic disease is being redefined through patient-led data learning and the Internet of Things. This text offers a guided tour of machine learning algorithms, architecture design, and applications of learning in healthcare. Readers will discover the ethical implications of machine learning in healthcare and the future of machine learning in population and patient health optimization. This book can also help assist in the creation of a machine learning model, performance evaluation, and the operationalization of its outcomes within organizations. It may appeal to computer science/information technology professionals and researchers working in the area of machine learning, and is especially applicable to the healthcare sector. The features of this book include: A unique and complete focus on applications of machine learning in the healthcare sector. An examination of how data analysis can be done using healthcare data and bioinformatics. An investigation of how healthcare companies can leverage the tapestry of big data to discover new business values. An exploration of the concepts of machine learning, along with recent research developments in healthcare sectors.

Machine Learning for Knowledge Discovery with R: Methodologies for Modeling, Inference and Prediction

by Kao-Tai Tsai

Machine Learning for Knowledge Discovery with R contains methodologies and examples for statistical modelling, inference, and prediction of data analysis. It includes many recent supervised and unsupervised machine learning methodologies such as recursive partitioning modelling, regularized regression, support vector machine, neural network, clustering, and causal-effect inference. Additionally, it emphasizes statistical thinking of data analysis, use of statistical graphs for data structure exploration, and result presentations. The book includes many real-world data examples from life-science, finance, etc. to illustrate the applications of the methods described therein. Key Features: Contains statistical theory for the most recent supervised and unsupervised machine learning methodologies. Emphasizes broad statistical thinking, judgment, graphical methods, and collaboration with subject-matter-experts in analysis, interpretation, and presentations. Written by statistical data analysis practitioner for practitioners. The book is suitable for upper-level-undergraduate or graduate-level data analysis course. It also serves as a useful desk-reference for data analysts in scientific research or industrial applications.

Machine Learning for Materials Discovery: Numerical Recipes and Practical Applications (Machine Intelligence for Materials Science)

by Hariprasad Kodamana Ravinder Bhattoo N. M. Krishnan

Focusing on the fundamentals of machine learning, this book covers broad areas of data-driven modeling, ranging from simple regression to advanced machine learning and optimization methods for applications in materials modeling and discovery. The book explains complex mathematical concepts in a lucid manner to ensure that readers from different materials domains are able to use these techniques successfully. A unique feature of this book is its hands-on aspect—each method presented herein is accompanied by a code that implements the method in open-source platforms such as Python. This book is thus aimed at graduate students, researchers, and engineers to enable the use of data-driven methods for understanding and accelerating the discovery of novel materials.

Machine Learning for Networking: 6th International Conference, MLN 2023, Paris, France, November 28–30, 2023, Revised Selected Papers (Lecture Notes in Computer Science #14525)

by Selma Boumerdassi Éric Renault Paul Mühlethaler

This book constitutes the refereed proceedings of the 6th International Conference on Machine Learning for Networking, MLN 2023, held in Paris, France, during November 28–30, 2023. The 18 full papers included in this book were carefully reviewed and selected from 34 submissions. The conference aims at providing a top forum for researchers and practitioners to present and discuss new trends in machine learning, deep learning, pattern recognition and optimization for network architectures and services.

Machine Learning for Real World Applications (Transactions on Computer Systems and Networks)

by Dinesh K. Sharma H. S. Hota Aaron Rasheed Rababaah

This book provides a comprehensive coverage of machine learning techniques ranging from fundamental to advanced. The content addresses topics within the scope of the book from the ground up, providing readers with a trustworthy source of theoretical and technical learning content. The book emphasizes not only the theoretical features but also their practical and implementation aspects in real-world applications. These applications are crucial because they provide comprehensive experimental work that supports the validity of the offered approaches as well as clear instructions on how to apply such models in comparable and distinct settings and contexts. Furthermore, the chapters shed light on the problems and possibilities that researchers might use to direct their future research efforts. The book is beneficial for undergraduate and postgraduate students, researchers, and industry personnel.

Machine Learning for Social Transformation: Proceedings of EAIT 2024 (Lecture Notes in Networks and Systems #1131)

by Debashis De Jyotsna Kumar Mandal

The book includes original unpublished contributions presented at the Eighth International Conference on Emerging Applications of Information Technology (EAIT 2024), organized by Computer Society of India, Kolkata Chapter during 12 – 13 January 2024. The Theme of the conference is “Machine Learning for Social Transformation”. The book covers the topics such as computational intelligence for social transformation, machine learning for healthcare informatics, and machine learning for agriculture and environmental sustainability.

Machine Learning for Time Series Forecasting with Python

by Francesca Lazzeri

Learn how to apply the principles of machine learning to time series modeling with this indispensable resource Machine Learning for Time Series Forecasting with Python is an incisive and straightforward examination of one of the most crucial elements of decision-making in finance, marketing, education, and healthcare: time series modeling. Despite the centrality of time series forecasting, few business analysts are familiar with the power or utility of applying machine learning to time series modeling. Author Francesca Lazzeri, a distinguished machine learning scientist and economist, corrects that deficiency by providing readers with comprehensive and approachable explanation and treatment of the application of machine learning to time series forecasting. Written for readers who have little to no experience in time series forecasting or machine learning, the book comprehensively covers all the topics necessary to: Understand time series forecasting concepts, such as stationarity, horizon, trend, and seasonality Prepare time series data for modeling Evaluate time series forecasting models’ performance and accuracy Understand when to use neural networks instead of traditional time series models in time series forecasting Machine Learning for Time Series Forecasting with Python is full real-world examples, resources and concrete strategies to help readers explore and transform data and develop usable, practical time series forecasts. Perfect for entry-level data scientists, business analysts, developers, and researchers, this book is an invaluable and indispensable guide to the fundamental and advanced concepts of machine learning applied to time series modeling.

Machine Learning from Weak Supervision: An Empirical Risk Minimization Approach (Adaptive Computation and Machine Learning series)

by Nan Lu Masashi Sugiyama Han Bao Takashi Ishida Tomoya Sakai

Fundamental theory and practical algorithms of weakly supervised classification, emphasizing an approach based on empirical risk minimization.Standard machine learning techniques require large amounts of labeled data to work well. When we apply machine learning to problems in the physical world, however, it is extremely difficult to collect such quantities of labeled data. In this book Masashi Sugiyama, Han Bao, Takashi Ishida, Nan Lu, Tomoya Sakai and Gang Niu present theory and algorithms for weakly supervised learning, a paradigm of machine learning from weakly labeled data. Emphasizing an approach based on empirical risk minimization and drawing on state-of-the-art research in weakly supervised learning, the book provides both the fundamentals of the field and the advanced mathematical theories underlying them. It can be used as a reference for practitioners and researchers and in the classroom.The book first mathematically formulates classification problems, defines common notations, and reviews various algorithms for supervised binary and multiclass classification. It then explores problems of binary weakly supervised classification, including positive-unlabeled (PU) classification, positive-negative-unlabeled (PNU) classification, and unlabeled-unlabeled (UU) classification. It then turns to multiclass classification, discussing complementary-label (CL) classification and partial-label (PL) classification. Finally, the book addresses more advanced issues, including a family of correction methods to improve the generalization performance of weakly supervised learning and the problem of class-prior estimation.

Machine Learning in Biotechnology and Life Sciences: Build machine learning models using Python and deploy them on the cloud

by Saleh Alkhalifa

Explore all the tools and templates needed for data scientists to drive success in their biotechnology careers with this comprehensive guideKey FeaturesLearn the applications of machine learning in biotechnology and life science sectorsDiscover exciting real-world applications of deep learning and natural language processingUnderstand the general process of deploying models to cloud platforms such as AWS and GCPBook DescriptionThe booming fields of biotechnology and life sciences have seen drastic changes over the last few years. With competition growing in every corner, companies around the globe are looking to data-driven methods such as machine learning to optimize processes and reduce costs. This book helps lab scientists, engineers, and managers to develop a data scientist's mindset by taking a hands-on approach to learning about the applications of machine learning to increase productivity and efficiency in no time.You'll start with a crash course in Python, SQL, and data science to develop and tune sophisticated models from scratch to automate processes and make predictions in the biotechnology and life sciences domain. As you advance, the book covers a number of advanced techniques in machine learning, deep learning, and natural language processing using real-world data.By the end of this machine learning book, you'll be able to build and deploy your own machine learning models to automate processes and make predictions using AWS and GCP.What you will learnGet started with Python programming and Structured Query Language (SQL)Develop a machine learning predictive model from scratch using PythonFine-tune deep learning models to optimize their performance for various tasksFind out how to deploy, evaluate, and monitor a model in the cloudUnderstand how to apply advanced techniques to real-world dataDiscover how to use key deep learning methods such as LSTMs and transformersWho this book is forThis book is for data scientists and scientific professionals looking to transcend to the biotechnology domain. Scientific professionals who are already established within the pharmaceutical and biotechnology sectors will find this book useful. A basic understanding of Python programming and beginner-level background in data science conjunction is needed to get the most out of this book.

Machine Learning in Clinical Neuroimaging: 7th International Workshop, MLCN 2024, Held in Conjunction with MICCAI 2024, Marrakesh, Morocco, October 10, 2024, Proceedings (Lecture Notes in Computer Science #15266)

by Vinod Kumar Yiming Xiao Mohamad Habes Thomas Wolfers Deepti R. Bathula Nicha C. Dvornek Sindhuja T. Govindarajan Anoop Benet Nirmala Ahmed Nebli

This book constitutes the refereed proceedings of the 7th International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2024, held in Conjunction with MICCAI 2024 in Marrakesh, Morocco, on 10th October 2024. The 16 full papers presented in this volume were carefully reviewed and selected from 28 submissions. They are grouped into the following topics: machine learning; clinical applications.

Machine Learning in Cognitive IoT

by Neeraj Kumar Aaisha Makkar

This book covers the different technologies of Internet, and machine learning capabilities involved in Cognitive Internet of Things (CIoT). Machine learning is explored by covering all the technical issues and various models used for data analytics during decision making at different steps. It initiates with IoT basics, its history, architecture and applications followed by capabilities of CIoT in real world and description of machine learning (ML) in data mining. Further, it explains various ML techniques and paradigms with different phases of data pre-processing and feature engineering. Each chapter includes sample questions to help understand concepts of ML used in different applications. Explains integration of Machine Learning in IoT for building an efficient decision support system Covers IoT, CIoT, machine learning paradigms and models Includes implementation of machine learning models in R Help the analysts and developers to work efficiently with emerging technologies such as data analytics, data processing, Big Data, Robotics Includes programming codes in Python/Matlab/R alongwith practical examples, questions and multiple choice questions

Machine Learning in Educational Sciences: Approaches, Applications and Advances

by Myint Swe Khine

This comprehensive volume investigates the untapped potential of machine learning in educational settings. It examines the profound impact machine learning can have on reshaping educational research. Each chapter delves into specific applications and advancements, sheds light on theory-building, and multidisciplinary research, and identifies areas for further development. It encompasses various topics, such as machine-based learning in psychological assessment. It also highlights the power of machine learning in analyzing large-scale international assessment data and utilizing natural language processing for science education. With contributions from leading scholars in the field, this book provides a comprehensive, evidence-based framework for leveraging machine-learning approaches to enhance educational outcomes. The book offers valuable insights and recommendations that could help shape the future of educational sciences.

Machine Learning in Finance: From Theory to Practice

by Matthew F. Dixon Igor Halperin Paul Bilokon

This book introduces machine learning methods in finance. It presents a unified treatment of machine learning and various statistical and computational disciplines in quantitative finance, such as financial econometrics and discrete time stochastic control, with an emphasis on how theory and hypothesis tests inform the choice of algorithm for financial data modeling and decision making. With the trend towards increasing computational resources and larger datasets, machine learning has grown into an important skillset for the finance industry. This book is written for advanced graduate students and academics in financial econometrics, mathematical finance and applied statistics, in addition to quants and data scientists in the field of quantitative finance. Machine Learning in Finance: From Theory to Practice is divided into three parts, each part covering theory and applications. The first presents supervised learning for cross-sectional data from both a Bayesian and frequentist perspective. The more advanced material places a firm emphasis on neural networks, including deep learning, as well as Gaussian processes, with examples in investment management and derivative modeling. The second part presents supervised learning for time series data, arguably the most common data type used in finance with examples in trading, stochastic volatility and fixed income modeling. Finally, the third part presents reinforcement learning and its applications in trading, investment and wealth management. Python code examples are provided to support the readers' understanding of the methodologies and applications. The book also includes more than 80 mathematical and programming exercises, with worked solutions available to instructors. As a bridge to research in this emergent field, the final chapter presents the frontiers of machine learning in finance from a researcher's perspective, highlighting how many well-known concepts in statistical physics are likely to emerge as important methodologies for machine learning in finance.

Machine Learning in Finance: Trends, Developments and Business Practices in the Financial Sector (Contributions to Finance and Accounting)

by Musa Gün Burcu Kartal

This book discusses the evolution of technical features in decentralized finance and focuses on machine-learning finance in emerging economies. As technological advancement evolves at an unpredictable pace, the financial industry, like every other sector, must adapt accordingly. Furthermore, the rapid expansion of diverse financial products and services is creating new applications and markets. Alongside technological progress, the exploration of complex patterns in vast amounts of data, known as big data, is facilitated by its commonly acknowledged characteristics: volume, variety, veracity, value, and velocity. Overall, machine learning has become crucial in the financial industry, allowing businesses to automate operations, gain insights from data, and make more informed decisions in real time. This edited book covers algorithmic trading, risk management, fraud detection, customer service and personalization, portfolio management, credit scoring, sentiment analysis, and algorithmic pricing. The book connects theoretical concepts with practical real-world applications, benefiting professionals looking to enhance their proficiency in using these methods efficiently. It offers insightful guidance for theorists, market participants, and policymakers by exploring financial theories and practices in light of contemporary machine-learning approaches, with a special emphasis on emerging economies.

Machine Learning in Medical Imaging: 15th International Workshop, MLMI 2024, Held in Conjunction with MICCAI 2024, Marrakesh, Morocco, October 6, 2024, Proceedings, Part I (Lecture Notes in Computer Science #15241)

by Islem Rekik Xuanang Xu Zhiming Cui Xi Ouyang Kaicong Sun

This book constitutes the proceedings of the 15th International Workshop on Machine Learning in Medical Imaging, MLMI 2023, held in conjunction with MICCAI 2024, Marrakesh, Morocco, on October 6, 2024. The 63 full papers presented in this volume were carefully reviewed and selected from 100 submissions. They focus on major trends and challenges in the above-mentioned area, aiming to identify new-cutting-edge techniques and their uses in medical imaging using artificial intelligence (AI) and machine learning (ML).

Machine Learning in Medical Imaging: 15th International Workshop, MLMI 2024, Held in Conjunction with MICCAI 2024, Marrakesh, Morocco, October 6, 2024, Proceedings, Part II (Lecture Notes in Computer Science #15242)

by Islem Rekik Xuanang Xu Zhiming Cui Xi Ouyang Kaicong Sun

This book constitutes the proceedings of the 15th International Workshop on Machine Learning in Medical Imaging, MLMI 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, on October 6, 2024. The 63 full papers presented in this volume were carefully reviewed and selected from 100 submissions. They focus on major trends and challenges in the above-mentioned area, aiming to identify new-cutting-edge techniques and their uses in medical imaging using artificial intelligence (AI) and machine learning (ML).

Machine Learning in Medicine

by Aeilko H. Zwinderman Ton J. Cleophas

Machine learning is a novel discipline concerned with the analysis of large and multiple variables data. It involves computationally intensive methods, like factor analysis, cluster analysis, and discriminant analysis. It is currently mainly the domain of computer scientists, and is already commonly used in social sciences, marketing research, operational research and applied sciences. It is virtually unused in clinical research. This is probably due to the traditional belief of clinicians in clinical trials where multiple variables are equally balanced by the randomization process and are not further taken into account. In contrast, modern computer data files often involve hundreds of variables like genes and other laboratory values, and computationally intensive methods are required. This book was written as a hand-hold presentation accessible to clinicians, and as a must-read publication for those new to the methods.

Machine Learning in Medicine - Cookbook Two

by Aeilko H. Zwinderman Ton J. Cleophas

The amount of data medical databases doubles every 20 months, and physicians are at a loss to analyze them. Also, traditional data analysis has difficulty to identify outliers and patterns in big data and data with multiple exposure / outcome variables and analysis-rules for surveys and questionnaires, currently common methods of data collection, are, essentially, missing. Consequently, proper data-based health decisions will soon be impossible. Obviously, it is time that medical and health professionals mastered their reluctance to use machine learning methods and this was the main incentive for the authors to complete a series of three textbooks entitled "Machine Learning in Medicine Part One, Two and Three, Springer Heidelberg Germany, 2012-2013", describing in a nonmathematical way over sixty machine learning methodologies, as available in SPSS statistical software and other major software programs. Although well received, it came to our attention that physicians and students often lacked time to read the entire books, and requested a small book, without background information and theoretical discussions and highlighting technical details. For this reason we produced a 100 page cookbook, entitled "Machine Learning in Medicine - Cookbook One", with data examples available at extras. springer. com for self-assessment and with reference to the above textbooks for background information. Already at the completion of this cookbook we came to realize, that many essential methods were not covered. The current volume, entitled "Machine Learning in Medicine - Cookbook Two" is complementary to the first and also intended for providing a more balanced view of the field and thus, as a must-read not only for physicians and students, but also for any one involved in the process and progress of health and health care. Similarly to Machine Learning in Medicine - Cookbook One, the current work will describe stepwise analyses of over twenty machine learning methods, that are, likewise, based on the three major machine learning methodologies: Cluster methodologies (Chaps. 1-3) Linear methodologies (Chaps. 4-11) Rules methodologies (Chaps. 12-20) In extras. springer. com the data files of the examples are given, as well as XML (Extended Mark up Language), SPS (Syntax) and ZIP (compressed) files for outcome predictions in future patients. In addition to condensed versions of the methods, fully described in the above three textbooks, an introduction is given to SPSS Modeler (SPSS' data mining workbench) in the Chaps. 15, 18, 19, while improved statistical methods like various automated analyses and Monte Carlo simulation models are in the Chaps. 1, 5, 7 and 8. We should emphasize that all of the methods described have been successfully applied in practice by the authors, both of them professors in applied statistics and machine learning at the European Community College of Pharmaceutical Medicine in Lyon France. We recommend the current work not only as a training companion to investigators and students, because of plenty of step by step analyses given, but also as a brief introductory text to jaded clinicians new to the methods. For the latter purpose, background and theoretical information have been replaced with the appropriate references to the above textbooks, while single sections addressing "general purposes", "main scientific questions" and "conclusions" are given in place. Finally, we will demonstrate that modern machine learning performs sometimes better than traditional statistics does. Machine learning may have little options for adjusting confounding and interaction, but you can add propensity scores and interaction variables to almost any machine learning method.

Machine Learning in Medicine – A Complete Overview

by Aeilko H. Zwinderman Ton J. Cleophas

Adequate health and health care is no longer possible without proper data supervision from modern machine learning methodologies like cluster models, neural networks, and other data mining methodologies. The current book is the first publication of a complete overview of machine learning methodologies for the medical and health sector, and it was written as a training companion, and as a must-read, not only for physicians and students, but also for any one involved in the process and progress of health and health care.In this second edition the authors have removed the textual errors from the first edition. Also, the improved tables from the first edition, have been replaced with the original tables from the software programs as applied. This is, because, unlike the former, the latter were without error, and readers were better familiar with them.The main purpose of the first edition was, to provide stepwise analyses of the novel methods from data examples, but background information and clinical relevance information may have been somewhat lacking. Therefore, each chapter now contains a section entitled "Background Information".Machine learning may be more informative, and may provide better sensitivity of testing than traditional analytic methods may do. In the second edition a place has been given for the use of machine learning not only to the analysis of observational clinical data, but also to that of controlled clinical trials.Unlike the first edition, the second edition has drawings in full color providing a helpful extra dimension to the data analysis.Several machine learning methodologies not yet covered in the first edition, but increasingly important today, have been included in this updated edition, for example, negative binomial and Poisson regressions, sparse canonical analysis, Firth's bias adjusted logistic analysis, omics research, eigenvalues and eigenvectors.

Machine Learning in Protein Science: Efficient Prediction of Protein Structures and Properties

by Jinjin Li Yanqiang Han

Harness the power of machine learning for quick and efficient calculations of protein structures and properties Machine Learning in Protein Science is a unique and practical reference that shows how to employ machine learning approaches for full quantum mechanical (FQM) calculations of protein structures and properties, thereby saving costly computing time and making this technology available for routine users. Machine Learning in Protein Science provides comprehensive coverage of topics including: Machine learning models and algorithms, from deep neural network (DNN) and transfer learning (TL) to hybrid unsupervised and supervised learning Protein structure predictions with AlphaFold to predict the effects of point mutations Modeling and optimization of the catalytic activity of enzymes Property calculations (energy, force field, stability, protein-protein interaction, thermostability, molecular dynamics) Protein design and large language models (LLMs) of protein systems Machine Learning in Protein Science is an essential reference on the subject for biochemists, molecular biologists, theoretical chemists, biotechnologists, and medicinal chemists, as well as students in related programs of study.

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