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ODE/PDE Analysis of Multiple Myeloma: Programming in R

by William E. Schiesser

Multiple myeloma is a form of bone cancer. Specifically, it is a cancer of the plasma cells found in bone marrow (bone soft tissue). Normal plasma cells are an important part of the immune system. Mathematical models for multiple myeloma based on ordinary and partial differential equations (ODE/PDEs) are presented in this book, starting with a basic ODE model in Chapter 1, and concluding with a detailed ODE/PDE model in Chapter 4 that gives the spatiotemporal distribution of four dependent variable components in the bone marrow and peripheral blood: (1) protein produced by multiple myeloma cells, termed the M protein, (2) cytotoxic T lymphocytes (CTLs), (3) natural killer (NK) cells, and (4) regulatory T cells (Tregs). The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers using the R routines that are available through a download. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences.

Odyssee im Zeptoraum

by Gian Francesco Giudice

Der Band lädt Leser ein, die Teilchenphysik mit den Augen eines Insiders zu betrachten, dadurch bieten sich neue Einblicke in die Welt der Teilchen und ihrer Wechselwirkungen. Aufschlussreich und unterhaltsam thematisieren die Autoren die Geschichte des Large Hadron Collider (LHC) und erläutern die mit dem LHC verknüpften wissenschaftlichen Fragen: Existiert das mysteriöse Higgs-Teilchen wirklich? Erstreckt sich der Raum in zusätzliche Dimensionen? Das Buch verhilft dazu, die Entdeckungen der kommenden Jahre mitzuverfolgen und nachzuvollziehen.

Off-Diagonal Bethe Ansatz for Exactly Solvable Models

by Yupeng Wang Wen-Li Yang Junpeng Cao Kangjie Shi

This book serves as an introduction of the off-diagonal Bethe Ansatz method, an analytic theory for the eigenvalue problem of quantum integrable models. It also presents some fundamental knowledge about quantum integrability and the algebraic Bethe Ansatz method. Based on the intrinsic properties of R-matrix and K-matrices, the book introduces a systematic method to construct operator identities of transfer matrix. These identities allow one to establish the inhomogeneous T-Q relation formalism to obtain Bethe Ansatz equations and to retrieve corresponding eigenstates. Several longstanding models can thus be solved via this method since the lack of obvious reference states is made up. Both the exact results and the off-diagonal Bethe Ansatz method itself may have important applications in the fields of quantum field theory, low-dimensional condensed matter physics, statistical physics and cold atom systems.

The Official ACT Prep Guide

by Jossey-Bass Staff

Everything you need to know about the 2016-2017 ACT test, with real full-length practice tests from the makers of the ACT! The Official ACT Prep Guide 2016-2017 is the bestselling resource for students gearing up for the ACT test. This comprehensive guide walks you through the entire test experience, from registration through results, with expert advice straight from the test's creators. You'll find effective test-taking strategies, tips for boosting your score on the English, math, reading, and science tests, and detailed information on the enhanced optional writing test. Three new full-length practice tests help you assess your readiness so you can spot weak areas well in advance, and the ACT experts provide valuable advice on preparing both mentally and physically so you can manage anxiety and be fully confident on test day. You also get free online bonus content to help you start college on the right foot, including tips for preparing an application that gets noticed, getting into your first-choice school, being a successful student, and much more. The 2016-2017 version of the ACT guide includes a number of changes, including reading test sections with two shorter prose passages and the enhanced writing test's prompts. This guide provides a preview of what to expect for the entire exam, so you can go into the test feeling fully prepared and ready to excel.

The Official SAT Study Guide, 2016 Edition

by The College Board

The Official SAT Study Guide includes 4 official SAT® practice tests created by the test maker. As part of the College Board’s commitment to transparency, all four practice tests are available on the College Board’s website, but The Official SAT Study Guide is the only place to find them in print along with over 300 pages of additional instruction, guidance, and test information. Launching in March 2016, the new SAT introduces new question formats and content. Be ready with strategies and up-to-date information straight from the team that created the exam. Students will gain valuable experience and raise their confidence by taking practice tests, learning about test structure, and gaining a deeper understanding of what is tested on the SAT. The Official SAT Study Guide will help students get ready for the SAT with: • 4 official SAT practice tests, written in the exact same process and by the same team of authors as the actual exam • detailed descriptions of the math and evidenced based reading and writing sections of the SAT • targeted practice questions for each SAT question type • guidance on the new optional essay, including practice essay questions with sample responses • a review of math concepts tested in the exam • test-taking approaches and suggestions that underscore important points • seamless integration with Khan Academy's free SAT practice resources • scaled scoring for all 4 official SAT practice tests available in July on collegeboard.org There's also a complete chapter on the new PSAT/NMSQT®, which is aligned to the content and scores of the new SAT. The new PSAT/NMSQT also has over $180 million of scholarships connected to student performance. This is the guide for the new SAT that launches in March 2016 and the new PSAT/NMQST that launches in October 2015.

The Official SAT Study Guide (2018 Edition)

by The College Board

Review every skill and question type needed for SAT success - now with eight total practice tests. The 2018 edition of The Official SAT Study Guide doubles the number of official SAT#65533; practice tests to eight - all of them created by the test maker. As part of the College Board's commitment to transparency, all practice tests are available on the College Board's website, but The Official SAT Study Guide is the only place to find them in print along with over 250 pages of additional instruction, guidance, and test information. With updated guidance and practice problems that reflect the most recent information, this new edition takes the best-selling SAT guide and makes it even more relevant and useful. Be ready for the SAT with strategies and up-to-date information straight from the exam writers. The Official SAT Study Guide will help students get ready for the SAT with: * 8 official SAT practice tests, written in the exact same process and by the same team of authors as the actual exam * detailed descriptions of the math and evidenced based reading and writing sections * targeted practice questions for each SAT question type * guidance on the new optional essay, including practice essay questions with sample responses * seamless integration with Official SAT Practice on Khan Academy There's also a complete chapter on the PSAT/NMSQT#65533;, which is aligned to the content and scores of the new SAT. The PSAT/NMSQT also has over $180 million of scholarships connected to student performance.

Official Statistics 4.0: Verified Facts for People in the 21st Century

by Walter J. Radermacher

This book explores official statistics and their social function in modern societies. Digitisation and globalisation are creating completely new opportunities and risks, a context in which facts (can) play an enormously important part if they are produced with a quality that makes them credible and purpose-specific. In order for this to actually happen, official statistics must continue to actively pursue the modernisation of their working methods.This book is not about the technical and methodological challenges associated with digitisation and globalisation; rather, it focuses on statistical sociology, which scientifically deals with the peculiarities and pitfalls of governing-by-numbers, and assigns statistics a suitable position in the future informational ecosystem. Further, the book provides a comprehensive overview of modern issues in official statistics, embodied in a historical and conceptual framework that endows it with different and innovative perspectives. Central to this work is the quality of statistical information provided by official statistics. The implementation of the UN Sustainable Development Goals in the form of indicators is another driving force in the search for answers, and is addressed here.This book will be of interest to a broad readership. The topics of sociology, epistemology, statistical history and the management of production processes, which are important for official statistics and their role in social decision-making processes, are generally not dealt with in statistics books. The book is primary intended for official statisticians, but researchers and advanced students in statistics, economics, sociology and the political sciences will find the book equally stimulating. Last but not least, it offers a valuable source of reflection for policymakers and stakeholders.

Official Statistics—A Plaything of Politics?: On the Interaction of Politics, Official Statistics, and Ethical Principles

by Reimund Mink

This book describes official statistics as a tool to hold up a mirror to society – but also as an instrument for those who can manipulate this mirror. It addresses the precarious interaction of politics, official statistics, and ethical principles. Three sets of themes can be derived from this relationship, which are the focus of this book: Political systems and guiding principles, official statistics as a science of the state, and ethical issues arising from them. Ultimately, the determining factor is the political system that exists in each case.The book contains eleven chapters. The first three focus on the key concepts of the book: power and morality, official statistics and policy making, and ethical principles for statistical work. Three further chapters focus on episodes that illustrate, as "drastic" examples, the misuse of official statistics over the past hundred years, covering the situation in the Soviet Union, the Third Reich and Greece. The remaining five chapters take up current topics that pose particular challenges to official statistics. These are the phenomena paraphrased by digitalisation, globalisation, happiness research, overpopulation, migration, the Covid-19 pandemic and climate change.The book is primarily aimed at statisticians working in national and international statistical institutions, but also at readers interested in statistics, national accounts, economic and statistics history, and ethical issues.

Offshore Exploration of Oil and Gas in Cuba using Digital Elevation Models (SpringerBriefs in Earth System Sciences)

by Valia Suárez Leyva Odalys Reyes Paredes Manuel Enrique Pardo Echarte

This book provides an overview of the major changes induced by hydrocarbons (HCs) affecting rocks and surface sediments and their implications for non-seismic exploration methods, particularly for marine territories near Cuba. It examines the use of a digital elevation model (DEM) at 90x90m resolution for the detection of subtle, positive geomorphic anomalies related to hydrocarbon microseepage (vertical migration) on possible oil and gas targets. The results support the conclusion that the DEM data provides a low cost and fast offshore oil and gas preliminary exploration strategy. This data is useful serving to focus prospective areas with supplementary unconventional methods such as magnetic-induced polarization (MIP), useful to propose more expensive volumes for detailed 2D–3D seismic surveys.

Offshore Risk Assessment vol 1.: Principles, Modelling and Applications of QRA Studies

by Jan-Erik Vinnem

Offshore Risk Assessment was the first book to deal with quantified risk assessment (QRA) as applied specifically to offshore installations and operations. Risk assessment techniques have been used for more than three decades in the offshore oil and gas industry, and their use is set to expand increasingly as the industry moves into new areas and faces new challenges in older regions. This updated and expanded third edition has been informed by a major R&D program on offshore risk assessment in Norway and summarizes research from 2006 to the present day. Rooted with a thorough discussion of risk metrics and risk analysis methodology, subsequent chapters are devoted to analytical approaches to escalation, escape, evacuation and rescue analysis of safety and emergency systems. Separate chapters analyze the main hazards of offshore structures: fire, explosion, collision, and falling objects as well as structural and marine hazards. Risk mitigation and control are discussed, as well as an illustration of how the results from quantitative risk assessment studies should be presented. The third second edition has a stronger focus on the use of risk assessment techniques in the operation of offshore installations. Also decommissioning of installations is covered. Not only does Offshore Risk Assessment describe the state of the art of QRA, it also identifies weaknesses and areas that need further development. This new edition also illustrates applications or quantitative risk analysis methodology to offshore petroleum applications. A comprehensive reference for academics and students of marine/offshore risk assessment and management, the book should also be owned by professionals in the industry, contractors, suppliers, consultants and regulatory authorities.

Offshore Risk Assessment Vol. 1: Principles, Modelling and Applications of QRA Studies (Springer Series in Reliability Engineering)

by Jan-Erik Vinnem Willy Røed

This is the first textbook to address quantified risk assessment (QRA) as specifically applied to offshore installations and operations. As the first part of the two-volume updated and expanded fourth edition, it adds a new focus on the EU Offshore Safety Directive, and discusses the new perspective on risk from the Norwegian Petroleum Safety Authority, followed by new and updated international standards. New safety statistics for the Norwegian sectors are presented, as well as new case studies on international offshore accidents, such as the explosion on FPSO Sao Mateus in 2015, which involved 9 fatalities. Separate chapters analyse the main hazards for offshore structures: fire, explosion, collision, and falling objects, as well as structural and marine hazards. Risk mitigation and control are discussed, as well as how the results of quantitative risk assessment studies should be presented. The fourth edition presents updated hydrocarbon release statistics, together with new methods for modelling the risk from ignited hydrocarbon releases. There have been recent advances in the modelling of collision risk from passing and attending vessels, based on extensive research; these advances are described in detail, in addition to new developments in the safety of Dynamic Positioning vessels. In closing, the book provides updated statistics and lessons learned from accidents involving offshore helicopter transportation of personnel. The book offers a comprehensive reference guide for academics and students of marine/offshore risk assessment and management. It will also be of interest to professionals in the industry, as well as contractors, suppliers, consultants and regulatory authorities.

Offshore Risk Assessment Vol. 2: Principles, Modelling and Applications of QRA Studies (Springer Series in Reliability Engineering)

by Jan-Erik Vinnem Willy Røed

This is the first textbook to address quantified risk assessment (QRA) as specifically applied to offshore installations and operations. As the second part of the two-volume updated and expanded fourth edition, it adds a new focus on the recent development of Normally Unattended Installations (NUIs), which are essentially autonomous installations that combine digitalization, big data, drones and machine learning, and can be supported by W2W (walk-to-work) vessels. These minimalistic installations with no helideck and very limited safety systems will require a new approach to risk assessment and emergency planning, especially during manned periods involving W2W vessels. Separate chapters analyse the main hazards for offshore structures: fire, explosion, collision, and falling objects, as well as structural and marine hazards. The book explores possible simplifications of risk assessment for traditional manned installations. Risk mitigation and control are also discussed, as well as how the results of quantitative risk assessment studies should be presented. In closing, the book provides an updated approach to environmental risk assessment. The book offers a comprehensive reference guide for academics and students of marine/offshore risk assessment and management. It will also be of interest to professionals in the industry, as well as contractors, suppliers, consultants and regulatory authorities.

Offshoring Strategies: Evolving Captive Center Models

by Ilan Oshri

The evolution of a rapidly growing mode of offshoring, captive centers: basic models, strategies, and case studies of Fortune Global 250 firms.In today's globalized economy, firms often consider offshoring when confronted by rising costs and fierce competition. One mode of offshoring has continued to grow despite the current global economic turmoil: the captive center. Captive centers are offshore subsidiaries or branch offices that provide the parent company with services, usually in the form of back-office activities. In Offshoring Strategies, Ilan Oshri examines the evolution of the captive center. He identifies basic captive center models, examines the captive center strategies pursued by Fortune Global 250 firms, describes current captive center trends, and offers detailed individual case studies that illustrate each model. His analysis highlights the strategic paths available to firms that want to maximize the returns offered by captive centers. Oshri outlines six models for captive centers that range from the basic wholly owned branch office to hybrids and joint ventures and identifies evolutionary paths along which the basic model develops. He analyzes firms' strategies during initial set-up, then tracks the changes as strategies evolve to meet different business needs. The case studies, all based on the Fortune Global 250, include the development of a basic captive unit into a complex hybrid structure; the evolution a captive center into a shared service center offering services to other international firms; the divestment of a captive center to a private equity firm; and the migration of a captive center to a location where costs were lower.

Offspring: Human Fertility Behavior in Biodemographic Perspective

by Kenneth W. Wachter Rodolfo A. Bulatao

Despite recent advances in our understanding of the genetic basis of human behavior, little of this work has penetrated into formal demography. Very few demographers worry about how biological processes might affect voluntary behavior choices that have demographic consequences even though behavioral geneticists have documented genetics effects on variables such as parenting and divorce. Offspring: Human Fertility Behavior in Demographic Perspective brings together leading researchers from a wide variety of disciplines to review the state of research in this emerging field and to identify promising research directions for the future.

Ohio Performance Coach, Mathematics, [Grade 7]

by Triumph Learning Llc

NIMAC-sourced textbook

Oklahoma Math Connects: Concepts, Skills, and Problem Solving, Course 3

by Glencoe McGraw-Hill

Students can master Oklahoma's Priority Academic Student Skills in 3 Easy Steps: 1. Practice the Standards throughout the Lessons, 2. Practice the Standards throughout the Chapter, and 3. Practice the Standards before the Test.

Ökonometrie: Eine Einführung (Springer-Lehrbuch)

by Ludwig Auer

Dieses Lehrbuch bietet eine praxisorientierte Einführung in die Methoden der Ökonometrie. Angesichts der zunehmenden Bedeutung der empirischen Analyse in Wissenschaft und Praxis will das Buch die Ökonometrie aus ihrer formal-mathematischen Ecke herausholen und einem breiteren Interessentenkreis zugänglich machen. In der Konzeption des Lehrbuches erhielt deshalb didaktisches Profil grundsätzlich Vorrang vor wissenschaftlicher Eleganz. Unterstützt durch zahlreiche Illustrationen, ausführliche verbale Erläuterungen und begleitende numerische Beispiele werden sowohl die ökonometrischen Grundlagen als auch anspruchsvollere Themenbereiche in gut verständlicher Art und Weise aufbereitet. Das Lehrbuch kommt ohne den Einsatz von Matrixalgebra aus. Ambitionierte Leser finden jedoch in den jeweiligen Kapitelanhängen ausführliche matrixalgebraische Darstellungen des behandelten Materials.

Ökonometrie in Theorie und Praxis: Analyse von Querschnitt-, Zeitreihen- und Paneldaten mit Stata 15.1

by Panchanan Das

Dieses Buch führt in die ökonometrische Analyse von Querschnitts-, Zeitreihen- und Paneldaten unter Anwendung statistischer Software ein. Es dient als Grundlagentext für diejenigen, die ökonometrische Analysen in der empirischen Forschung erlernen und anwenden wollen. Das Niveau der Darstellung ist so einfach wie möglich gehalten, um es sowohl für Studenten im Grundstudium als auch für Doktoranden nützlich zu machen. Es enthält mehrere Beispiele mit realen Daten und Stata-Programmen sowie die Interpretation der Ergebnisse. Bei der Diskussion der statistischen Instrumente, die zum Verständnis der empirischen Wirtschaftsforschung erforderlich sind, versucht das Buch, ein Gleichgewicht zwischen Theorie und angewandter Forschung herzustellen. Verschiedene Konzepte und Techniken der ökonometrischen Analyse werden durch sorgfältig entwickelte Beispiele unter Verwendung des statistischen Softwarepakets Stata 15.1 unterstützt, wobei vorausgesetzt wird, dass der Leser mit der Software Strata einigermaßen vertraut ist.

Ökonometrie und maschinelles Lernen: Basiswissen für Ökonomen (essentials)

by Silvio Andrae

Für empirische Wirtschaftswissenschaftler gehören ökonometrische Methoden zum Standardwerkzeug. Die neuen Instrumente des maschinellen Lernens setzen sich langsam auch in der Volks- und Betriebswirtschaftslehre durch. Das Buch vermittelt Basiswissen zu den spezifischen Methoden des überwachten und unüberwachten Lernens sowie des Verstärkungslernens. Dabei werden die wesentlichen Unterschiede in Bezug auf Ziele, Methoden und Rahmenbedingungen zwischen den Methoden der Ökonometrie und des maschinellen Lernens dargestellt und erörtert.

Ökonomische Grundlagen der Finanzwirtschaft: Von der Main Street zur Wall Street

by Thorsten Hens Sabine Elmiger

Dieses Buch vermittelt dem Leser die wesentlichen Konzepte der Finanzwirtschaft für eine integrierte Betrachtung des Finanzsystems und der Realwirtschaft. Es wird erörtert, wie die langfristigen Marktpreise durch Bevölkerungswachstum, technischen Fortschritt und nicht erneuerbare Ressourcen bestimmt und beeinflusst werden. Die Bedeutung von Marktpreisen wird sowohl aus der Perspektive der Haushalte als auch aus der Perspektive der Unternehmen untersucht. Das Buch verbindet somit verschiedene Bereiche des Finanzwesens, die sich in der Regel entweder nur auf die Seite der Haushalte oder nur auf die Seite der Unternehmen konzentrieren.

Old Age In Europe: A Textbook of Gerontology

by Marja Aartsen Kathrin Komp

Europe currently is the oldest continent in the world and its population is still ageing. This demographic shift affects society, economy, and welfare states. Scholars from various disciplines and the public noted this development and wonder what effects it may have, but lack adequate information. They call for explanations that are concise and easily accessible. The book at hand fills this lacuna. It introduces readers to the most important developments, theories, concepts, and discussions in ageing studies - always keeping an eye on the current situation in Europe. Each chapter adopts the perspective of a different discipline, e.g. public health, sociology, economics, or technology. To make the explanations easy to understand, the book includes learning tools such as learning objectives, multiple choice questions, and a glossary.

Old and New Perspectives on Mortality Forecasting (Demographic Research Monographs)

by Tommy Bengtsson Nico Keilman

This open access book describes methods of mortality forecasting and discusses possible improvements. It contains a selection of previously unpublished and published papers, which together provide a state-of-the-art overview of statistical approaches as well as behavioural and biological perspectives. The different parts of the book provide discussions of current practice, probabilistic forecasting, the linearity in the increase of life expectancy, causes of death, and the role of cohort factors. The key question in the book is whether it is possible to project future mortality accurately, and if so, what is the best approach. This makes the book a valuable read to demographers, pension planners, actuaries, and all those interested and/or working in modelling and forecasting mortality.

Old Dogs, New Math: Homework Help For Puzzled Parents

by Mike Askew Rob Eastaway

“Perfect for parents who want to understand the different methods to do arithmetic their children are learning—and why they are being taught that way.” —Keith Devlin, award-winning Stanford University mathematician “Can you help me with my math homework?” If this question fills you with fear (or even panic), then Old Dogs, New Math is here to help! Gone are the days when elementary school students simply memorized their times tables and struggled through long division. Today, students are expected not just to find the right answer, but also to use the best method—and to explain why it works. If your attempts to help your child are met with “That’s not how the teacher does it,” then it’s time to take the stress out of math homework. Old Dogs, New Math demystifies Common Core math for parents, including: Number lines, place value and negative numbers Long multiplication and division Fractions, percentages and decimals Shapes, symmetry and angles Data analysis, probability and chance Complete with sample questions, examples of children’s errors, and over 25 games and activities, Old Dogs, New Math will not only help you and your child subtract on a number line or multiply on a grid—but also help you discover math all around you, and have fun doing it!

Older Mexicans and Latinos in the United States: Where Worlds Meet

by Jacqueline L. Angel Flavia C. Drumond Andrade Fernando Riosmena Silvia Mejia-Arango

This book delves into the consequences of rapid population aging for Mexico and U.S. Latinos, impacting various institutions, including families, the labor force, and healthcare systems. It examines in depth the causes and consequences of the increasing prevalence of cognitive impairment and dementia, especially early-onset decline in the Mexican-origin population. The book identifies resilience factors as critical to successful aging and health in the Mexican and Mexican-American populations from a transdisciplinary perspective. It also examines the diversity in the experiences of older adults with dementia and related disorders and that of their families in Mexico and the United States. The book also helps to better understand the levels of need and support capacity in both nations and the organizational contexts of long-term care in both countries. The ultimate goal of this sixth volume in the series on aging in the Americas is to identify critical sources of vulnerability and possible policy options for closing the gap in affordable and sustainable long-term care and financial wellbeing for low-resource populations living with dementia and other medical conditions in both countries. The volume presents new information, consensus data, potential venues for intervention, and action frameworks to advance current knowledge grounded in global aging health systems research of closing disparities in vulnerable populations at high risk of declining cognitive and physical health in two different political contexts. As such, the book provides a wealth of information for researchers, policy makers and professionals in the field of population aging.

Omic Association Studies with R and Bioconductor

by Juan R. González Alejandro Cáceres

After the great expansion of genome-wide association studies, their scientific methodology and, notably, their data analysis has matured in recent years, and they are a keystone in large epidemiological studies. Newcomers to the field are confronted with a wealth of data, resources and methods. This book presents current methods to perform informative analyses using real and illustrative data with established bioinformatics tools and guides the reader through the use of publicly available data. Includes clear, readable programming codes for readers to reproduce and adapt to their own data. Emphasises extracting biologically meaningful associations between traits of interest and genomic, transcriptomic and epigenomic data Uses up-to-date methods to exploit omic data Presents methods through specific examples and computing sessions Supplemented by a website, including code, datasets, and solutions

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