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Quantitative Approaches to Microcirculation: Mathematical Models, Computational Methods and Data Analysis (SEMA SIMAI Springer Series #36)

by Paolo Zunino Kent-Andre Mardal Andreas Linninger

Microcirculation is a key area of interest within the realms of biology and medicine. As a vital discipline, microcirculatory biology forms a significant part of established medical fields like cardiovascular medicine and oncology, and is increasingly relevant in emerging fields such as neuroscience. With its multifaceted nature, the study of microcirculation has evolved from basic observations and experiments to embrace cutting-edge imaging technologies, quantitative methods, and the power of data science. This volume brings together a series of insightful chapters that highlight the latest trends in modeling microcirculation. It casts a spotlight on the vital role of microcirculation in brain function modeling and the innovative applications of microvascular models in oncology. Readers will be introduced to state-of-the-art methodologies of microcirculation modeling. A key focus is on mixed-dimensional models, mathematical methods adept at describing complex interactions within lower dimensional manifolds. Each chapter thoughtfully navigates the mathematical, computational, and practical challenges of these approaches, underscoring their effectiveness in capturing the essence of microcirculation. This book offers a window into the latest advancements and methodologies that are shaping the future of this vital field.

Quantitative Approximations

by George Anastassiou

Quantitative approximation methods apply in many diverse fields of research-neural networks, wavelets, partial differential equations, probability and statistics, functional analysis, and classical analysis to name just a few. For the first time in book form, Quantitative Approximations provides a thorough account of all of the significant developm

Quantitative Aptitude - 2024 Edition - Competitive Exam

by Dr R. S. Aggarwal

The reference book Quantitative Aptitude for Competitive Examinations by Dr. R.S. Aggarwal, published by S. Chand and Company Limited, is designed for candidates preparing for a wide range of competitive exams such as IBPS, SBI, RBI, SSC, UPSC, and more. It provides comprehensive coverage of mathematical topics essential for quantitative reasoning, with over 2000 solved examples and more than 10,000 practice questions. The content is organized by topics such as the number system, HCF and LCM, decimal fractions, simplifications, square roots, and various types of arithmetic problems. It also includes shortcuts, detailed solutions, video content, and mock tests for thorough exam preparation.

Quantitative Assessment of Securitisation Deals

by Wim Schoutens Henrik Jönsson Francesca Campolongo

The book draws on current research on model risk and parameter sensitivity of securitisation ratings. It provides practical ideas and tools that can facilitate a more informed usage of securitisation ratings. We show how global sensitivity analysis techniques can be used to better analyse and to enhance the understanding of the uncertainties inherent in ratings due to uncertainty in the input parameters. The text introduces a novel global rating approach that takes the uncertainty in the ratings into account when assigning ratings to securitisation products. The book also covers new prepayment and default models that overcome flaws in current models.

Quantitative Betriebswirtschaftslehre Band II: Markttheorie, Investition und Finanzierung

by Thomas Bonart Jürgen Bär

Das dreibändige Lehrbuch „Quantitative BWL“ stellt die theoretischen quantitativen Grundlagen der betrieblichen Entscheidungen und des marktwirtschaftlichen Umfelds dar. Es ist für Studierende der Wirtschaftswissenschaften und des Wirtschaftsingenieurwesens im Bachelor- und Masterprogramm konzipiert. Auch komplexe Inhalte werden durch zahlreiche Beispiele verständlich und anschaulich erklärt. Zu jedem Kapitel gibt es Übungsaufgaben mit Lösungshinweisen. Somit eignet sich das Lehrbuch zur Unterstützung von Vorlesungen, aber auch zum autodidaktischen Lernen.

Quantitative Betriebswirtschaftslehre Band III: Marketing und Marktforschung, Technische Zuverlässigkeit

by Thomas Bonart Jürgen Bär

Das dreibändige Lehrbuch „Quantitative BWL“ stellt die theoretischen quantitativen Grundlagen der betrieblichen Entscheidungen und des marktwirtschaftlichen Umfelds dar. Es ist für Studierende der Wirtschaftswissenschaften und des Wirtschaftsingenieurwesens im Bachelor- und Masterprogramm konzipiert. Auch komplexe Inhalte werden durch zahlreiche Beispiele verständlich und anschaulich erklärt. Zu jedem Kapitel gibt es Übungsaufgaben mit Lösungshinweisen. Somit eignet sich das Lehrbuch zur Unterstützung von Vorlesungen, aber auch zum autodidaktischen Lernen.

Quantitative Biology: A Practical Introduction (Learning Materials in Biosciences)

by Akatsuki Kimura

This textbook is for biologists, to conduct quantitative analysis and modeling of biological processes at molecular and cellular levels. Focusing on practical concepts and techniques for everyday research, this text will enable beginners, both students and established biologists, to take the first step in quantitative biology. It also provides step-by-step tutorials to run various sample programs in one’s personal computer using Excel and Python. This volume traces topics, starting with an introductory chapter, such as modeling, construction and execution of numerical models, and key concepts in quantitative biology: feedback regulations, fluctuations and randomness, and statistical analyses. It also provide sample codes with guidance to procedure programming for actual biological processes such as movement of the nucleus within a cell, cell-cycle regulation, stripe pattern formation of skins, and distribution of energy. Written by a leading research scientist who has a background in biology, studied quantitative approaches by himself, and teaches quantitative biology at several universities, this textbook broadens quantitative approaches for biologists who do not have a strong background in mathematics, physics, or computer programming, and helps them progress further in their research.

Quantitative Comparisons & Data Interpretations Math GRE Strategy Guide

by Manhattan Gre Staff

Updated for the revised GRE, this guide is really two books in one, thoroughly covering two of the quantitative question types on the GRE. The Guide to Quantitative Comparisons provides students a framework for understanding what Quantitative Comparisons questions tests. Most importantly, it discusses time-saving strategies specific to the Quantitative Comparisons format. The Guide to Data Interpretation presents an overview of the types of graphs students can expect to see on the GRE. It also discusses the different types of questions typically seen on the GRE and provides guidelines for reading graphs and combining information from different graphs to answer questions. Purchase of this book includes one year of access to 6 of Manhattan GRE's online practice exams.

Quantitative Corporate Finance

by John B. Guerard Jr. Anureet Saxena Mustafa Gultekin

This textbook presents a comprehensive treatment of the legal arrangement of the corporation, the instruments and institutions through which capital can be raised, the management of the flow of funds through the individual firm, and the methods of dividing the risks and returns among the various contributors of funds.Now in its second edition, the book covers a wide range of topics in corporate finance, from time series modeling and regression analysis to multi-factor risk models and the Capital Asset Pricing Model. Guerard, Gultekin and Saxena build significantly on the first edition of the text, but retain the core chapters on cornerstone topics such as mergers and acquisitions, regulatory environments, bankruptcy and various other foundational concepts of corporate finance.New to the second edition are examinations of APT portfolio selection and time series modeling and forecasting through SAS, SCA and OxMetrics programming, FactSet fundamental data templates. This is intended to be a graduate-level textbook, and could be used as a primary text in upper level MBA and Financial Engineering courses, as well as a supplementary text for graduate courses in financial data analysis and financial investments.

Quantitative Corporate Finance

by John B. Guerard Jr. Anureet Saxena Mustafa N. Gültekin

This textbook presents a comprehensive treatment of the legal arrangement of the corporation, the instruments and institutions through which capital can be raised, the management of the flow of funds through the individual firm, and the methods of dividing the risks and returns among the various contributors of funds.Now in its third edition, the book covers a wide range of topics in corporate finance, from time series modeling and regression analysis to multi-factor risk models and the Capital Asset Pricing Model. Guerard, Gultekin and Saxena build significantly on the first edition of the text, but retain the core chapters on cornerstone topics such as mergers and acquisitions, regulatory environments, bankruptcy and various other foundational concepts of corporate finance.New to the third edition are examinations of APT portfolio selection and time series modeling and forecasting through SAS, SCA and OxMetrics programming, FactSet fundamental data templates. This is intended to be a graduate-level textbook, and could be used as a primary text in upper level MBA and Financial Engineering courses, as well as a supplementary text for graduate courses in financial data analysis and financial investments.

Quantitative Data Analysis with SPSS 12 and 13: A Guide for Social Scientists

by Alan Bryman Duncan Cramer

This new edition has been completely updated to accommodate the needs of users of SPSS Release 12 and 13 for Windows, whilst still being applicable to those using SPSS Release 11 and 10. Alan Bryman and Duncan Cramer provide a non-technical approach to quantitative data analysis and a user-friendly introduction to the widely used SPSS. No previous familiarity with computing or statistics is required to benefit from this step-by-step guide to techniques including: Non-parametric tests Correlation Simple and multiple regression Multivarate analysis of variance and covariance Factor analysis The authors discuss key issues facing the newcomer to research, such as how to decide which statistical procedure is suitable, and how to interpret the subsequent results. Each chapter contains worked examples to illustrate the points raised and ends with a comprehensive range of exercises which allow the reader to test their understanding of the topic. This new edition of this hugely successful textbook will guide the reader through the basics of quantitative data analysis and become an essential reference tool for both students and researchers in the social sciences. The datasets used in Quantitative Data Analysis for SPSS Release 12 and 13 are available online at www.psypress.com/brymancramer/ .

Quantitative Decisions in Drug Development (Springer Series in Pharmaceutical Statistics)

by Christy Chuang-Stein Simon Kirby

This book focuses on important decision points and evidence needed for making decisions at these points during the development of a new drug. It takes a holistic approach towards drug development by incorporating explicitly knowledge learned from the earlier part of the development and available historical information into decisions at later stages. In addition, the book shares lessons learned from several select examples published in the literature since the publication of the first edition. The second edition reiterates the need for making evidence-based Go/No Go decisions in drug development discussed in the first edition. It substantially expands several topics that have seen great advances since the publication of the first edition. The most noticeable additions include three adaptive trials conducted in recent years that offer excellent learning opportunities, the use of historical data in the design and analysis of clinical trials, and extending decision criteria to the cases when the primary endpoint is binary. The examples used to illustrate the additional materials all come from real trials with some post-trial reflections offered by the authors. The book begins with an overview of product development and regulatory approval pathways. It then discusses how to incorporate prior knowledge into study design and decision making at different stages of drug development. Prior knowledge includes information pertaining to historical controls. To assist decision making, the book discusses appropriate metrics and the formulation of go/no-go decisions for progressing a drug candidate to the next development stage. Using the concept of the positive predictive value in the field of diagnostics, the book leads readers to the assessment of the probability that an investigational product is effective given positive study outcomes. Lastly, the book points out common mistakes made by drug developers under the current drug-development paradigm. The book offers useful insights to statisticians, clinicians, regulatory affairs managers and decision-makers in the pharmaceutical industry who have a basic understanding of the drug-development process and the clinical trials conducted to support drug-marketing authorization. The authors provide software codes for select analytical approaches discussed in the book. The book includes enough technical details to allow statisticians to replicate the quantitative illustrations so that they can generate information to facilitate decision-making themselves.

Quantitative Demography and Health Estimates: Healthy Life Expectancy, Templates for Direct Estimates from Life Tables and other Applications (The Springer Series on Demographic Methods and Population Analysis #55)

by Christos H Skiadas Charilaos Skiadas

This book provides new theoretic and applied material with focus on quantitative methods and data analysis techniques applied in demography, population studies, health issues and statistics. It discusses the quantitative techniques to estimate the healthy life expectancy by expanding the classical life tables to include the proportion with disability calculated from life tables, along with the Sullivan method. The provided templates apply immediately to the life tables from WHO, HMD, Eurostat and other life table providers. Furthermore, the book explores the possibility of creating new health indicators along with Covid-19 pandemic management, factors associated to loneliness and an alcohol indicator. Part of the book is devoted to mortality, epidemic models, and the supercentenarians age estimation. Data analysis and artificial intelligence methods are included to apply in demographic and socio-economic cases. By providing a methodology to cope with health problems in demography and society by quantifying important health parameters, this book is a valuable guide for researchers, theoreticians, and practitioners from various disciplines and especially health scientists, statisticians, economists, and sociologists.

Quantitative Drug Safety and Benefit Risk Evaluation: Practical and Cross-Disciplinary Approaches (Chapman & Hall/CRC Biostatistics Series)

by William Wang Melvin Munsaka James Buchanan Judy X. Li

Quantitative Methodologies and Process for Safety Monitoring and Ongoing Benefit Risk Evaluation provides a comprehensive coverage on safety monitoring methodologies, covering both global trends and regional initiatives. Pharmacovigilance has traditionally focused on the handling of individual adverse event reports however recently there had been a shift towards aggregate analysis to better understand the scope of product risks. Written to be accessible not only to statisticians but also to safety scientists with a quantitative interest, this book aims to bridge the gap in knowledge between medical and statistical fields creating a truly multi-disciplinary approach that is very much needed for 21st century safety evaluation.

Quantitative Economics with R: A Data Science Approach

by Vikram Dayal

This book provides a contemporary treatment of quantitative economics, with a focus on data science. The book introduces the reader to R and RStudio, and uses expert Hadley Wickham’s tidyverse package for different parts of the data analysis workflow. After a gentle introduction to R code, the reader’s R skills are gradually honed, with the help of “your turn” exercises. At the heart of data science is data, and the book equips the reader to import and wrangle data, (including network data). Very early on, the reader will begin using the popular ggplot2 package for visualizing data, even making basic maps. The use of R in understanding functions, simulating difference equations, and carrying out matrix operations is also covered. The book uses Monte Carlo simulation to understand probability and statistical inference, and the bootstrap is introduced. Causal inference is illuminated using simulation, data graphs, and R code for applications with real economic examples, covering experiments, matching, regression discontinuity, difference-in-difference, and instrumental variables. The interplay of growth related data and models is presented, before the book introduces the reader to time series data analysis with graphs, simulation, and examples. Lastly, two computationally intensive methods—generalized additive models and random forests (an important and versatile machine learning method)—are introduced intuitively with applications. The book will be of great interest to economists—students, teachers, and researchers alike—who want to learn R. It will help economics students gain an intuitive appreciation of applied economics and enjoy engaging with the material actively, while also equipping them with key data science skills.

Quantitative Ecotoxicology

by Michael C. Newman

Quantitative Ecotoxicology, Second Edition explores models and methods of quantitative ecotoxicology at progressively higher biological scales using worked examples and common software packages. It complements the author's previous books, Fundamentals of Ecotoxicology, Third Edition and Ecotoxicology: A Comprehensive Treatment. Encouraging a more r

Quantitative Energy Finance: Recent Trends and Developments

by Fred Espen Benth Almut E. D. Veraart

Power markets are undergoing a major transformation from gas and oil-fueled generation toward renewable electricity production from wind and solar sources. Simultaneously, there is an increasing demand for electrification, coupled with long-term climate-induced weather changes. The uncertainties confronting energy market participants require sophisticated modelling techniques to effectively understand risk, many of which are covered in this book.Comprising invited papers by high-profile researchers, this volume examines the empirical aspects of forward and futures prices, uncovering patterns of noise factors in various European electricity markets. Additionally, it delves into the recent, influential classes of Hawkes and trawl processes, emphasizing their significance in energy markets. The impact of renewables on energy market prices is a pivotal concern for both producers and consumers. Mean-field games provide a powerful mathematical framework for this, and a dedicated chapter outlining their dynamics is included in the book. The book also explores structural financial products and their connection to climate risk as a risk management tool, underscoring the essential need for a comprehensive understanding of these products in the realm of "green finance," to which the energy industry is integral. Lastly, the book thoroughly analyzes spatial smoothing and power purchase (PPA) contracts, addressing central issues in energy system planning and financial operations.Tailored for researchers, PhD students, and industry energy analysts, this volume equips readers with insights and tools to navigate the constantly evolving energy market landscape. It serves as a sequel to the earlier Quantitative Energy Finance book, featuring all-new chapters.

Quantitative Energy Finance: Modeling, Pricing, and Hedging in Energy and Commodity Markets

by Valery Kholodnyi Fred Espen Benth Peter Laurence

Finance and energy markets have been an active scientific field for some time, even though the development and applications of sophisticated quantitative methods in these areas are relatively new--and referred to in a broader context as energy finance. Energy finance is often viewed as a branch of mathematical finance, yet this area continues to provide a rich source of issues that are fuelling new and exciting research developments. Based on a special thematic year at the Wolfgang Pauli Institute (WPI) in Vienna, Austria, this edited collection features cutting-edge research from leading scientists in the fields of energy and commodity finance. Topics discussed include modeling and analysis of energy and commodity markets, derivatives hedging and pricing, and optimal investment strategies and modeling of emerging markets, such as power and emissions. The book also confronts the challenges one faces in energy markets from a quantitative point of view, as well as the recent advances in solving these problems using advanced mathematical, statistical and numerical methods. By addressing the emerging area of quantitative energy finance, this volume will serve as a valuable resource for graduate-level students and researchers studying financial mathematics, risk management, or energy finance.

Quantitative Epidemiology (Emerging Topics in Statistics and Biostatistics)

by Xinguang Chen

This book is designed to train graduate students across disciplines within the fields of public health and medicine, with the goal of guiding them in the transition to independent researchers. It focuses on theories, principles, techniques, and methods essential for data processing and quantitative analysis to address medical, health, and behavioral challenges. Students will learn to access to existing data and process their own data, quantify the distribution of a medical or health problem to inform decision making; to identify influential factors of a disease/behavioral problem; and to support health promotion and disease prevention. Concepts, principles, methods and skills are demonstrated with SAS programs, figures and tables generated from real, publicly available data. In addition to various methods for introductory analysis, the following are featured, including 4-dimensional measurement of distribution and geographic mapping, multiple linear and logistic regression, Poisson regression, Cox regression, missing data imputing, and statistical power analysis.

Quantitative Equity Portfolio Management: Modern Techniques and Applications (Chapman and Hall/CRC Financial Mathematics Series)

by Edward E. Qian Ronald H. Hua Eric H. Sorensen

Quantitative equity portfolio management combines theories and advanced techniques from several disciplines, including financial economics, accounting, mathematics, and operational research. While many texts are devoted to these disciplines, few deal with quantitative equity investing in a systematic and mathematical framework that is suitable for

Quantitative Ethnography

by David Williamson Shaffer

Quantitative Ethnography is an engaging introduction to research methods for students, an introduction to data science for qualitative researchers, and an introduction to the humanities for statisticians-but also a compelling philosophical and intellectual journey for anyone who wants to understand learning, culture and behavior in the age of big data.

Quantitative Evaluation of Fire and EMS Mobilization Times

by Robert Upson Kathy A. Notarianni

Quantitative Evaluation of Fire and EMS Mobilization Times presents comprehensive empirical data on fire emergency and EMS call processing and turnout times, and aims to improve the operational benchmarks of NFPA peer consensus standards through a close examination of real-world data. The book also identifies and analyzes the elements that can influence EMS mobilization response times. Quantitative Evaluation of Fire and EMS Mobilization Times is intended for practitioners as a tool for analyzing fire emergency response times and developing methods for improving them. Researchers working in a related field will also find the book valuable.

Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting (Chapman & Hall/CRC Biostatistics Series)

by Qi Jiang H. Amy Xia

State-of-the-Art Methods for Drug Safety AssessmentResponding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both clinical trials and observational studies in biopharmaceutical product deve

Quantitative Evaluation of Systems: 18th International Conference, QEST 2021, Paris, France, August 23–27, 2021, Proceedings (Lecture Notes in Computer Science #12846)

by Alessandro Abate Andrea Marin

This book constitutes the proceedings of the 18th International Conference on Quantitative Evaluation Systems, QEST 2021, held in Paris, France, in August 2021.The 21 full papers and 2 short papers presented together with 2 keynote papers were carefully reviewed and selected from 47 submissions. The papers are organized in the following topics: probabilistic model checking; quantitative models and metamodels: analysis and validation; queueing systems; learning and verification; simulation; performance evaluation; abstractions and aggregations; and stochastic models.

Quantitative Evaluation of Systems

by Gul Agha Benny Van Houdt

This book constitutes the proceedings of the 13th International Conference on Quantitative Evaluation Systems, QEST 2016, held in Quebec City, Canada, in August 2016. The 21 full papers and 3 tool demonstration papers presented were carefully reviewed and selected from 46 submissions. They are organized in topical sections entitled: Markov processes; tools; sampling, inference, and optimization methods; Markov decision processes and Markovian analysis; networks.

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