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Evolutionary Genomics
by Maria AnisimovaTogether with early theoretical work in population genetics, the debate on sources of genetic makeup initiated by proponents of the neutral theory made a solid contribution to the spectacular growth in statistical methodologies for molecular evolution. Evolutionary Genomics: Statistical and Computational Methods is intended to bring together the more recent developments in the statistical methodology and the challenges that followed as a result of rapidly improving sequencing technologies. Presented by top scientists from a variety of disciplines, the collection includes a wide spectrum of articles encompassing theoretical works and hands-on tutorials, as well as many reviews with key biological insight. Volume 2 begins with phylogenomics and continues with in-depth coverage of natural selection, recombination, and genomic innovation. The remaining chapters treat topics of more recent interest, including population genomics, -omics studies, and computational issues related to the handling of large-scale genomic data. Written in the highly successful Methods in Molecular BiologyTM series format, this work provides the kind of advice on methodology and implementation that is crucial for getting ahead in genomic data analyses. Comprehensive and cutting-edge, Evolutionary Genomics: Statistical and Computational Methods is a treasure chest of state-of the-art methods to study genomic and omics data, certain to inspire both young and experienced readers to join the interdisciplinary field of evolutionary genomics.
Evolutionary Gerontology and Geriatrics: Why and How We Age (Advances in Studies of Aging and Health #2)
by Giacinto Libertini Graziamaria Corbi Valeria Conti Olga Shubernetskaya Nicola FerraraThis book provides concrete scientific basis that we can conceive the possibility of modifying or even completely canceling aging process, despite the fact that aging is commonly regarded as the result of the overall effects of many uncontrollable degenerative phenomena. The authors illustrate in detail the mechanisms by which cells and the whole organism age. Actions by which it is possible, or will be possible within a limited time, to operate for modifying aging are also debated.The discussion is conducted within the frame and the concepts of evolutionary medicine, which is also indispensable for distinguishing between the manifestations of aging and: (i) diseases that worsen with age, and (ii) acceleration of normal aging rates, caused by unhealthy lifestyle habits and other avoidable factors. The book also discusses the impact of aging on overall mortality and the strange situation that, according to official statistics, aging does not exist as cause of death.This book is a turning point between a gerontology and geriatrics conceived as the study and vain treatment of an incurable condition and one in which these disciplines examine the how and why of a physiological phenomenon that can be modified up to a possible total control. This means transforming the medical prevention and treatment of physiological aging from the greatest failure to the greatest success of medicine.
Evolutionary Psychiatry: Current Perspectives on Evolution and Mental Health
by Riadh Abed St John-Smith, PaulEvolutionary psychiatry attempts to explain and examine the development and prevalence of psychiatric disorders through the lens of evolutionary and adaptationist theories. In this edited volume, leading international evolutionary scholars present a variety of Darwinian perspectives that will encourage readers to consider 'why' as well as 'how' mental disorders arise. Using insights from comparative animal evolution, ethology, anthropology, culture, philosophy and other humanities, evolutionary thinking helps us to re-evaluate psychiatric epidemiology, genetics, biochemistry and psychology. It seeks explanations for persistent heritable traits shaped by selection and other evolutionary processes, and reviews traits and disorders using phylogenetic history and insights from the neurosciences as well as the effects of the modern environment. By bridging the gap between social and biological approaches to psychiatry, and encouraging bringing the evolutionary perspective into mainstream psychiatry, this book will help to inspire new avenues of research into the causation and treatment of mental disorders.
Evolutionary Statistical Procedures
by Irene Poli Roberto Baragona Francesco BattagliaThis proposed text appears to be a good introduction to evolutionary computation for use in applied statistics research. The authors draw from a vast base of knowledge about the current literature in both the design of evolutionary algorithms and statistical techniques. Modern statistical research is on the threshold of solving increasingly complex problems in high dimensions, and the generalization of its methodology to parameters whose estimators do not follow mathematically simple distributions is underway. Many of these challenges involve optimizing functions for which analytic solutions are infeasible. Evolutionary algorithms represent a powerful and easily understood means of approximating the optimum value in a variety of settings. The proposed text seeks to guide readers through the crucial issues of optimization problems in statistical settings and the implementation of tailored methods (including both stand-alone evolutionary algorithms and hybrid crosses of these procedures with standard statistical algorithms like Metropolis-Hastings) in a variety of applications. This book would serve as an excellent reference work for statistical researchers at an advanced graduate level or beyond, particularly those with a strong background in computer science.
Evolutionary Systems Biology
by Orkun S. SoyerThe book aims to introduce the reader to the emerging field of Evolutionary Systems Biology, which approaches classical systems biology questions within an evolutionary framework. An evolutionary approach might allow understanding the significance of observed diversity, uncover "evolutionary design principles" and extend predictions made in model organisms to others. In addition, evolutionary systems biology can generate new insights into the adaptive landscape by combining molecular systems biology models and evolutionary simulations. This insight can enable the development of more detailed mechanistic evolutionary hypotheses.
Evolutionary Thinking in Medicine
by Alexandra Alvergne Crispin Jenkinson Charlotte FaurieThe aim of this edited book is to provide health professionals, across a wide variety of specialisms, with a targeted access to evolutionary medicine. Throughout the book, the views of both medical and evolutionary scientists on the latest relevant research is presented with a focus on practical implications. The inclusion of boxes explaining the theoretical background as well as both a glossary for technical terms and a lay summary for non- specialists enable medical researchers, public health professionals, policy makers, physicians, students, scholars and the public alike to quickly and easily access appropriate information. This edited volume is thus relevant to anyone keen on finding out how evolutionary medicine can improve the health and well-being of people.
Evolutionary and Comparative Neuroendocrinology (Masterclass in Neuroendocrinology #17)
by Valery Grinevich Rui F. OliveiraThis book delves into the intricate journey of neuroendocrine evolution, from its rudimentary origins in single-celled organisms to the complex systems found in mammals. It offers a comprehensive exploration of how neuropeptides and their receptors have evolved, highlighting the pivotal role of the hypothalamus and pituitary gland in this process. Key concepts covered include the evolution of neuropeptide signaling, insights from invertebrate hypothalamic-pituitary systems, and the functional trajectories of ancient peptide ligand-receptor systems. The book addresses critical questions such as the organization and evolution of neurotransmitter volume transmission, the form and function of growth hormone-releasing hormone across vertebrates, and the co-evolution of neuroendocrine signaling dyads. Chapters on the melanocortin system, corticotropin-releasing hormone, and nonapeptide regulation of social behavior in teleost fish provide a deep dive into specific pathways and their evolutionary significance. Aimed at researchers and professionals in neuroscience, endocrinology, and evolutionary biology, this text serves as an invaluable resource for anyone interested in the comparative anatomy and physiology of neuroendocrine systems. This is the seventeenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Evolutionäre Medizin: Eine Einführung für Mediziner und Biologen (essentials)
by Werner BuselmaierWerner Buselmaier erläutert, dass die evolutionäre Medizin den Menschen als Ergebnis einer langen Entwicklung sieht. Diese Betrachtungsweise im Licht der Evolution ist für das Verständnis der Natur des gesunden wie des kranken Menschen von außerordentlicher Bedeutung. Die zunehmende Erkenntnis, dass es zum vollständigen Verständnis einer Krankheit sowohl unmittelbarer als auch evolutionsbiologischer Erklärungen bedarf, wird in allerjüngster Zeit auch in die Medizinerausbildung eingebracht.
Evolving Eldercare in Contemporary China
by Lin ChenWith an increasing number of elders moving into nursing homes, the shift from family to nursing home care calls for an exploration of caregiving decision-making in urban China. This study examines how a rapidly growing aging population, the one-child policy, and economic reform in urban China pose unprecedented challenges to the country's ingrained tradition of family caregiving. It presents interviews of matched elders and their children from a government-sponsored nursing home in Shanghai and analyzes the decision-making process of institutionalization. This book offers fresh insight into the evolving culture and arrangements of caregiving in contemporary Chinese society, illuminating the diverse needs for long-term care of Chinese elders-the world's largest aging population-in the coming decades.
Evolving Psychosis: Different Stages, Different Treatments (The International Society for Psychological and Social Approaches to Psychosis Book Series)
by Jan Olav Johannessen Brian V. Martindale Johan CullbergCan early, need-adapted treatment prevent the long-terms effects of psychosis? How important is phase-specific treatment? Evolving Psychosis explores the success of psycho-social treatments for psychosis in helping patients recover more quickly and stay well longer. Mental health professionals from all over the world share their clinical experience and scientific findings to shed new light on the issues surrounding need-specific treatment. They cover: The Nature of Psychosis, Early Intervention in Psychosis, Phase-Specific Treatment of Psychosis and The Need for Integration. Particular attention is paid to the how treatment can be improved with individually tailored treatment programmes, early intervention, more integration between psychological treatments, and new and better diagnostic concepts. This book incorporates new and controversial ideas which will stimulate discussion regarding the benefits of early, need-adapted treatment. It will be of interest to psychologists, psychiatrists and other mental health professionals interested in psycho-social approaches to psychosis.
Evolving Role of AI and IoMT in the Healthcare Market
by Manoj Kumar Fadi Al-Turjman Akashdeep Bhardwaj Thompson StephanThis book is a proficient guide to understanding artificial intelligence (IoT) and the Internet of Medical Things (IoMT) in healthcare. The book provides a comprehensive study on the applications of AI and IoT in various medical domains. The book shows how the implementation of innovative solutions in healthcare is beneficial, and IoT, together with AI, are strong drivers of the digital transformation regardless of what field the technologies are applied in. Therefore, this book provides a high level of understanding with the emerging technologies on the Internet of Things, wearable devices, and AI in IoMT, which offers the potential to acquire and process a tremendous amount of data from the physical world.
Ewing Sarcoma: Methods and Protocols (Methods in Molecular Biology #2226)
by Florencia Cidre-Aranaz Thomas G.P. GrünewaldThis volume aims at providing a selection of the most effective and widely employed protocols used in the Ewing sarcoma field. Chapters are divided into five sections detailing the molecular biology techniques used to analyze Ewing sarcoma including tissue preservation and methods used in morpho-molecular diagnostics and routine immune-histological analysis. Additional wet-lab protocols comprise in vitro techniques including re-expression and functional analyses of target genes together with in vivo tools and models such as patient-derived xenografts (PDX) and orthotopic xenografts for metastasis assessment in Ewing sarcoma. A full section on bioinformatic approaches to Ewing sarcoma covering ChIPseq, epigenetic and systems biology analyses finalizes this volume. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and clearly written, Ewing sarcoma: Methods and Protocols aims to provide methods to further the study of Ewing sarcoma and bring researchers one step forward in the quest to fight this devastating disease.
Ewing's Analytical Instrumentation Handbook, Fourth Edition
by Sonia Rodriguez Nelu GrinbergThis handbook is a guide for workers in analytical chemistry who need a starting place for information about a specific instrumental technique. It gives a basic introduction to the techniques and provides leading references on the theory and methodology for an instrumental technique. This edition thoroughly expands and updates the chapters to include concepts, applications, and key references from recent literature. It also contains a new chapter on process analytical technology.
Ex Vivo Engineering of the Tumor Microenvironment
by Amir R. Aref David BarbieThis volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
Exam Cram: NCLEX-PN (3rd Edition)
by Wilda Rinehart Diann Sloan Clara HurdSucceed with topical reviews, practice exams, and preparation tools "The book offers a quick 'cram' approach to the NCLEX that is user friendly and not time intensive. The overall approach is learner-centered and the content is well paced. " --Catherine Dearman, RN, PhD Covers exactly what you need to know to score higher on your NCLEX-PN® exam. Includes 400 sample test questions to help you determine whether you're ready to take the actual exam. Our popular Cram Sheet tearcard helps you remember key concepts. Exam Alerts provide important information found on the exam. Simplifies pharmacology for easy learning. Written by Leading Nursing Experts! Wilda Rinehart has R. N. , B. S. N. , M. S. N. , F. N. C. , and F. P. N. P. degrees. Her experience includes staff nurse in surgery, labor and delivery; public-health nurse; and family-planning nurse practitioner. She also was an instructor of surgical and obstetrical nursing. Diann Sloan has R. N. , B. S. N. , M. S. N. , F. N. C. , as well as MS. Ed. and Ph. D. in Education degrees. She has worked as a staff nurse in surgical nursing, pediatrics, and neonatal intensive care and as a pediatric nurse clinician. She has also been an instructor of pediatric and psychiatric nursing. Clara Hurd has M. S. N. , R. N. , and C. N. E. degrees. She has worked with Pearson as a consultant on item writing. She has 31 years of experience and has worked as a staff nurse in medical-surgical nursing and the surgical intensive care unit. Ms. Hurd has taught in associate and baccalaureate nursing programs. Score Higher on the NCLEX-PN® Exam! The CD features innovative Computer Adaptive Testing software, giving you an effective tool to assess your readiness for the NCLEX-PN® exam. Key features include: Detailed explanations of correct and incorrect answers Multiple test modes Random questions and order of answers System Requirements: Microsoft Windows XP, Microsoft Vista or Microsoft Windows 7 Pentium class 1GHz processor (or equivalent) 256MB RAM 30MB Hard Drive Space Category: Test Preparation and Review Covers: Nursing NCLEX-PN® is a registered trademark of the National Council of State Boards of Nursing, Inc. (NCSBN), which does not sponsor or endorse this product.
Exam Review for Beck's Theory and Practice of Therapeutic Massage, 5th edition
by Mark F. BeckThis printed exam review is created to offer students a fast and convenient way to prepare for licensing exams. Tens of thousands of students have successfully used our exam reviews to pass their exams with flying colors. Each exam review contains chapter-by-chapter questions in a multiple-choice format to help students prepare for their exams. The answer key at the back of the book allows students to check accuracy and identify weak areas.
Examination Notes in Psychiatry
by Peter Buckley Glynn Harrison Del Prewette Jonathan ByrdOver the last 20 years, Examination Notes in Psychiatry has become one of the leading texts for trainee psychiatrists. The 4th edition maintains the core of valuable information that is required by any would-be psychiatrist, but has been completely revised and updated. Assessment and diagnosis form the foundation to each section, but are now enhanc
Examination Of Orthopedic And Athletic Injuries
by Chad Starkey Sara D. Brown"This is by far the most comprehensive and user-friendly text for both professor and student! I am continuing to use it in my Athletic Training Program, and beginning next year, I will institute it into my PT courses in Ortho I & II."—Vincent J. Hudson, MS, PT, ATC, MBA, University of Central Florida, Orlando, Florida, review of a previous edition. Completely revised and updated, the 4th Edition of the field’s standard resource brings you all field’s most current knowledge and an all-new full-color art program. Its superb combination of detailed illustrations and precise language makes even the most complicated concepts and techniques clear. Organized by body region, each chapter begins with a review of anatomy and biomechanics; proceeds through clinical evaluation, pathologies, and related special tests; and concludes with a discussion of on-field or initial management of specific injuries. The Plus Code inside new, printed texts gives you access to the instructor and student resources online at DavisPlus, including your Davis Digital Version, range of motion animations, and review questions for every chapter.
Examination Questions and Answers in Basic Anatomy and Physiology: 2000 Multiple Choice Questions
by Martin CaonThis second edition provides 2400 multiple choice questions on human anatomy and physiology, and some physical science, separated into 40 categories. The answer to each question is accompanied by an explanation. Each category has an introduction to set the scene for the questions to come. However, not all possible information is provided within these Introductions, so an Anatomy and Physiology textbook is an indispensable aid to understanding the answers. The questions have been used in end-of-semester examinations for undergraduate anatomy and physiology courses and as such reflect the focus of these particular courses and are pitched at this level to challenge students that are beginning their training in anatomy and physiology.The question and answer combinations are intended for use by teachers, to select questions for their next examinations, and by students, when studying for an upcoming test. Students enrolled in the courses for which these questions were written include nursing, midwifery, paramedic, physiotherapy, occupational therapy, nutrition and dietetics, health sciences, exercise science, and students taking an anatomy and physiology course as an elective.
Examination Questions and Answers in Basic Anatomy and Physiology: 2900 Multiple Choice Questions and 64 Essay Topics
by Martin CaonThis third edition provides 2900 multiple choice questions on human anatomy and physiology, and some biophysical science, separated into 20 chapters and 68 categories. In addition, there are 64 essay topics. The answer to each question is accompanied by an explanation. Each chapter has an introduction to set the scene for the questions to come. However, not all possible information is provided within these Introductions, so an Anatomy and Physiology textbook is an indispensable aid to understanding the answers. The textbook offers a more holistic approach to the subjects of anatomy and physiology by also including biomechanics, biophysics and biochemistry. The questions have been used in end-of-semester examinations for undergraduate anatomy and physiology courses, and as such, reflect the focus of these particular courses and are pitched at this level to challenge students that are beginning their training in anatomy and physiology. The question and answer combinations are intended for use by teachers, to select questions for their next examinations, and by students, when studying for an upcoming test. Students enrolled in the courses for which these questions were written include nursing, midwifery, paramedic, physiotherapy, occupational therapy, nutrition and dietetics, health sciences, exercise science, and students taking an anatomy and physiology course as an elective.
Examination Review for Ultrasound: Abdomen And Obstetrics And Gynecology
by Steven PennyThis updated 2nd Edition of Examination Review for Ultrasound: Abdomen & Obstetrics and Gynecology helps students prepare for—and excel on—the ARDMS and ARRT certification exams. Focusing on only the information needed for exam success, this proven resource includes a concise, narrative approach, content based on the current exam, and an online exam simulator with registry-style questions.
Examination Review for Ultrasound: Abdomen and Obstetrics & Gynecology
by Steven M. PennyPrepare for—and excel on—the American Registry for Diagnostic Medical Sonography (ARDMS) and American Registry of Radiologic Technologists (ARRT) certification exams! Steven M. Penny’s Examination Review for Ultrasound: Abdomen & Obstetrics and Gynecology, 3rd Edition, focuses only on the information that you’ll see on these exams, saving you valuable study time. Now in full color throughout, it uses a concise, narrative approach and features an online exam simulator with hundreds of registry-style questions.
Examination Review for Ultrasound: Sonographic Principles And Instrumentation (spi)
by Steven Penny Traci FoxThis updated 2nd Edition of Examination Review for Ultrasound: Sonographic Principles & Instrumentation helps students prepare for—and excel on— the Sonography Principles and Instrumentation (SPI) certification examination offered by the ARDMS. Taking a concise, narrative approach, this proven resource aligns with the SPI revised content outline and format. An online exam simulator with registry-style questions makes it easy to create mock exams that allow unlimited practice.
Examination of Intraocular Fluid
by Yong Tao De-Kuang HwangThis book discusses the theory and new techniques in the examination of intraocular fluid. In the first part, authors introduce the collection, preservation and transportation of intraocular fluid, items of examination and common laboratory testing methods. In the second part, the diagnosis of infectious uveitis, non-infectious intraocular inflammation, masquerade syndrome and other diseases are covered. In each clinical case, fundus photography and ultrasound photos are also provided.
Examination of the Newborn
by Anne LomaxA practical, evidence-based guide for students and practitioners to undertake safe and effective neonatal examination Revised and updated throughout in line with current national and Nursing and Midwifery Council guidelines Full colour photographs and illustrations, as well as clinical case studies at the end of each chapter to help guide and illustrate good practice A new companion website contains a wealth of information on all aspects of examining the newborn, including safeguarding, early warning systems, and tongue tie, as well as interactive multiple choice questions, and links to videos