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Floored: A Woman's Guide to Pelvic Floor Health at Every Age and Stage
by Sara Reardon'A transformative guide to understanding and caring for the often-overlooked pelvic floor. A must-read for reclaiming comfort, dignity, and vitality' DR MARY-CLAIRE HAVER'should be required reading for everyone with a pelvic floor - which is everyone' Professor Emily OsterThe definitive guide to pelvic floor health, written by pelvic floor physical therapist and creator of the Vagina Whisperer, Dr Sara Reardon.Too many women put up with pelvic floor discomfort, thinking their symptoms are 'just part of motherhood and aging'. And for far too long, our health care system has normalized pelvic problems, leaving women feeling hopeless, ashamed and suffering in silence. Board-certified pelvic floor physical therapist Dr Sara Reardon helps women prevent and overcome common pelvic floor issues so they can trust and enjoy their bodies again.Floored is a rallying cry for women's health and the authoritative guide for the pelvic floor, a critical group of muscles involved in day-to-day functions, from wee-ing and poo-ing and sex and childbirth to menstruation and menopause. Whether you're navigating post-partum recovery, seeking relief from urinary incontinence or aiming to enhance sexual pleasure, this comprehensive resource provides the insights and strategies every woman needs.Inside the pages of this book, you will find:Education on pelvic floor anatomy and its critical role in your overall health. Practical advice for pelvic floor self-assessment and signs of potential issues.Exercises to strengthen, rehabilitate and maintain pelvic floor health across different life stages.Tips for treating common pelvic floor symptoms, such as involuntary urine leakage and painful sex.With clear and engaging guidance, Dr Reardon demystifies the complexities of pelvic floor care and provides everything you need to ensure your pelvic well-being.Learn about a variety of topics related to pelvic floor health, including:MenopauseMenstruationPregnancy and childbirthPostpartum carePainful sexIncontinence and prolapseVaginal hygieneThe time to take control of your pelvic health is now.
Florence Nightingale at Home
by Paul Crawford Anna Greenwood Richard Bates Jonathan MemelWinner of the 2021/2022 People's Book Prize Best Achievement AwardHomes can be both comforting and troubling places. This timely book proposes a new understanding of Florence Nightingale’s experiences of domestic life and how ideas of home influenced her writings and pioneering work. From her childhood homes in Derbyshire and Hampshire, she visited the poor sick in their cottages. As a young woman, feeling imprisoned at home, she broke free to become a woman of action, bringing home comforts to the soldiers in the Crimean War and advising the British population on the home front how to create healthier, contagion-free homes. Later, she created Nightingale Homes for nursing trainees and acted as mother-in-chief to her extended family of nurses. These efforts, inspired by her Christian faith and training in human care from religious houses, led to major changes in professional nursing and public health, as Nightingale strove for homely, compassionate care in Britain and around the world. Shedid most of this work from her bed after contracting the debilitating illness, brucellosis, in the Crimea, turning her various private homes into offices and ‘households of faith’. In the year of the bicentenary of her birth, she remains as relevant as ever, achieving an astonishing cultural afterlife.
Florence Nightingale: In Tribute to the Century of Women
by Daisaku IkedaFlorence Nightingale exemplified the incredible strength and capacity of a person fully awakened to her life's mission. Drawing inspiration from her life, eminent Buddhist philosopher and teacher Daisaku Ikeda shares insights that provide valuable lessons for men and women in today's world.
Florence Under Siege: Surviving Plague in an Early Modern City
by John HendersonA vivid recreation of how the governors and governed of early seventeenth-century Florence confronted, suffered, and survived a major epidemic of plaguePlague remains the paradigm against which reactions to many epidemics are often judged. Here, John Henderson examines how a major city fought, suffered, and survived the impact of plague. Going beyond traditional oppositions between rich and poor, this book provides a nuanced and more compassionate interpretation of government policies in practice, by recreating the very human reactions and survival strategies of families and individuals.From the evocation of the overcrowded conditions in isolation hospitals to the splendor of religious processions, Henderson analyzes Florentine reactions within a wider European context to assess the effect of state policies on the city, street, and family. Writing in a vivid and approachable way, this book unearths the forgotten stories of doctors and administrators struggling to cope with the sick and dying, and of those who were left bereft and confused by the sudden loss of relatives.
Flourishing: Health, Disease, and Bioethics in Theological Perspective
by Neil MesserWe use such words as "health," "disease," and "illness" all the time without stopping to consider exactly what we understand by them. Yet their meanings are far from straightforward, and disagreements over them have important practical consequences in health care and bioethics.In this book Neil Messer develops a distinctive and innovative theological account of these concepts. He engages in earnest with debates in the philosophy of medicine and disability studies and draws on a wide array of theological resources including Barth, Bonhoeffer, Aquinas, and recent disability theologies.By enabling us to understand health in the wider perspective of the flourishing and ultimate destiny of human beings, Messer's Flourishing sheds new light on a range of practical bioethical issues and dilemmas.
Flow Chemistry in Drug Discovery (Topics in Medicinal Chemistry #38)
by Antonio de la Hoz Jesus Alcazar Angel Díaz-OrtizThis book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development.
Flow Controlled Ventilation Mode Through a Straw Size Tube
by Nabil A. ShallikThis book focuses on Flow-controlled Ventilation (FCV), the most recent innovation in the field of airway management and ventilation. In this book, the authors explain how ventilation through a straw-size or ultra-thin endotracheal tube is possible with FCV along with the clinical application of FCV in managing complex cases, particularly those presenting for head and neck surgery for a narrow airway diameter, totally obstructed airway and various cases of “cannot intubate, cannot oxygenate” situation. Readers will learn: the physical and physiological principles governing how FCV works; how to prepare and setup the FCV ventilators to be used with ultra-thin tube (outer diameter 4.4 mm and inner diameter 2.4 mm); identifying commonly encountered issues and troubleshooting; how to manage various cases of difficult airway encountered in various settings (prehospital or intra-operatively); how to tackle a “Cannot intubate, Cannot oxygenate” scenario in a simple way. The book is intended to be a reference guide that could be easily carried during the daily clinical work with the aim of providing a better healthcare and promoting patients’ safety. It is intended for healthcare providers working in various clinical settings including but not limited to intensivists, anaesthetists, pulmonary physicians, medical residents, medical students, medical fellows, anaesthesia residents, nurses, anaesthesia technical staff, respiratory therapists, certified registered nurses in anaesthesia, and paramedics.
Flow Cytometry Basics for the Non-Expert (Techniques in Life Science and Biomedicine for the Non-Expert)
by Christine Goetz Christopher Hammerbeck Jody BonnevierThis first edition volume demystifies the complex topic of flow cytometry by providing detailed explanations and nearly 120 figures to help novice flow cytometry users learn and understand the bedrock principles necessary to perform basic flow cytometry experiments correctly.The book divides the topic of flow cytometry into easy to understand sections and covers topics such as the physics behind flow cytometry, flow cytometry lingo, designing flow cytometry experiments and choosing appropriate fluorochromes, compensation, sample preparation and controls and ways to assess cellular function using a variety of flow cytometry assays. Written as a series of chapters whose concepts sequentially build off one another, using the list of materials contained within each section along with the readily reproducible laboratory protocols and tips on troubleshooting that are included, readers should be able to reproduce the data figures presented throughout the book on their way to mastering sound basic flow cytometry techniques. Easy to understand and comprehensive, Flow Cytometry Basics for the Non-Expert will be a valuable resource to novice flow cytometry users as well as experts in other biomedical research fields who need to familiarize themselves with a basic understanding of how to perform flow cytometry and interpret flow cytometry data. This book is written for both scientists and non-scientists in academia, government, biotechnology, and medicine.
Flow Cytometry Today: Everything You Need to Know about Flow Cytometry
by Claudio OrtolaniThis book covers all the technical aspects of flow cytometry needed to set-up the instrument, solve problems encountered in daily work, or necessary for exam preparation. It provides the reader with an in-depth look at the device and its applications. Each component and its function is described in an easy-to-understand manner, giving the reader a sound basic knowledge of this instrument. The practical examples given, simplify and enhance the learning process. This book is a unique resource of knowledge for biomedical engineers and biotechnologists, flow cytometry operators, laboratory technicians and biomedical researchers, both biologists as well as medical doctors, and can also be a helpful tool for companies and manufacturers.
Flow Cytometry in Drug Discovery and Development
by Virginia Litwin Philip MarderThis book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one on flow cytometry and one on biomarkers, as well as a chapter on recent advances in flow cytometry. The second section focuses on the unique challenges and added benefits associated with the use of flow cytometry in the drug development process. The third section contains a single chapter presenting an in depth discussion of validation considerations and regulatory compliance issues associated with drug development.
Flow Cytometry in Neoplastic Hematology: Morphologic-Immunophenotypic Correlation, Third Edition
by Wojciech GorczycaThis third edition is the product of the author’s 25 years of experience with flow cytometry; although it covers the wide spectrum of hematopoietic tumors, the focus remains on most important clinical diagnoses, such as acute promyelocytic leukemia, identification of blasts, identification of clonal B-cell population, differentiating mature versus immature T-cell proliferations, deferential diagnosis between hematogones and B-ALL or distinction between chronic and acute monocytic proliferations. All hematopathologists and neoplastic hematologists will find this an important resource for keeping up to date with developments in clinical practice.
Flow Cytometry in Neoplastic Hematology: Morphologic-Immunophenotypic-Genetic Correlation
by Wojciech GorczycaThis fourth edition presents an updated and expanded text and illustrations to reflect continued morphologic, immunophenotypic, and especially molecular advances in the field of neoplastic hematology, mostly due to the rapidly expanding application of next-generation sequencing. Those advances not only allow a more reliable diagnosis of the majority of tumors and identification of early changes such as monoclonal B-cell lymphocytosis or clonal hematopoiesis of indeterminate potential (CHIP), but also in many cases identify mutations or phenotypic changes in tumors that can be targeted by mutation-specific or antigen-specific drugs. This edition incorporates the updated WHO classification of hematopoietic tumors and new immunophenotypic and molecular markers to provide a thorough pathologic overview of hematologic neoplasms while focusing on flow cytometric features. Special emphasis has been put on hematological neoplasms with crucial clinical significance such as acute promyelocytic leukemia, other acute leukemias, and difficult areas in flow cytometry. Flow cytometric features in AML, MDS, CMML, CLL and measurable residual disease were significantly expanded. There are many new comparative tables, illustrations, and diagrams of algorithmic approaches.
Flow Cytometry of Hematological Malignancies
by Claudio OrtolaniFlow Cytometry of Hematological Malignancies contains an array of graphical outputs produced by the technique in the study of the most (and the least) common diseases. The images included allow you to compare your own results with a third party reference pattern. There is a detailed description of the main leukocyte antigens, together with a description of their distribution amongst normal and abnormal blood cells. The book also provides a comprehensive description of the phenotype of every neoplastic blood disease recorded in the WHO classification system, including all the instructions needed to recognise and classify even the least common entity.Designed to be practical, the book is perfect for quick consultation and is divided into two main sections. Section I deals with the direct object of immunophenotyping, and Section II deals with the ultimate target of the analysis. More than 50 antigens are covered and every antigen is dealt with in three main parts: general features, cytometric features and practical hints.This authoritative and state-of-the-art reference will be invaluable for clinicians directly involved in the diagnosis and analysis of hematological diseases, including hematologists, hematopathologists, oncologists, pathologists and technicians working in diagnostic laboratories.
Flow Cytometry of Hematological Malignancies
by Claudio OrtolaniFlow cytometric analysis is often integral to the swift and accurate diagnosis of leukemias and lymphomas of the blood, bone marrow, and lymph nodes. However, in the fast-moving and expanding field of clinical hematology, in can be challenging to remain up to speed with the latest biological research and technological innovations. Flow Cytometry of Hematological Malignancies has been designed to provide all those working in hematological oncology with a practical, cutting-edge handbook, featuring clear and fully illustrated guidance on all aspects of cytometry’s role in diagnosis and analysis. This essential second edition includes: Explorations of more than 70 antigens Full-color illustrations throughout New descriptions of recently discovered markers WHO classifications of hematological neoplastic diseases Helpful tips for result interpretation and analysis Featuring all this and more, Flow Cytometry of Hematological Malignancies, Second Edition, is an invaluable resource for both trainee and experienced hematologists, hematopathologists, oncologists, and pathologists, as well as medical students and diagnostic lab technicians.
Flow Cytometry: Advanced Research and Clinical Applications, Volume I
by Andrew YenThe current technology and its applications in flow cytometry are presented in this comprehensive reference work. Described in explicit detail are the instrumentation and its components, and applications of the technology in cell biology, immunology, pharmacology, genetics, hematology and clinical medicine. Methods for data analysis, including both hardware and software, and explicit experimental techniques for making specific measurements are presented.Material is divided by topic into two volumes: Volume I covers instrumentation, genetics, and cell structure; Volume II contains material on cell function studies by flow cytometry.This reference is essential for both the novice and the experienced investigator using flow cytometry in research, and for students of cell biology, biomedical engineering, and medical technology.
Flow Cytometry: Advanced Research and Clinical Applications, Volume II
by Andrew YenThe current technology and its applications in flow cytometry are presented in this comprehensive reference work. Described in explicit detail are the instrumentation and its components, and applications of the technology in cell biology, immunology, pharmacology, genetics, hematology and clinical medicine. Methods for data analysis, including both hardware and software, and explicit experimental techniques for making specific measurements are presented.Material is divided by topic into two volumes: Volume I covers instrumentation, genetics, and cell structure; Volume II contains material on cell function studies by flow cytometry.This reference is essential for both the novice and the experienced investigator using flow cytometry in research, and for students of cell biology, biomedical engineering, and medical technology.
Flow Cytometry: Applications in Cellular and Molecular Toxicology
by Ab Pant Puneet Khare Alok Kumar PandeyThe book explores the role of flow cytometry in varied fields, from clinical diagnosis to toxicology. This comprehensive book offers insights into biomarkers, cellular analysis, and safety evaluations. Organized into fifteen chapters, this book explores flowcytometry's historical journey, scientific validation, and implementation in toxicity studies with case studies, technical and applied approaches, pictorial representations, informative tables, and simple language, It will be an invaluable resource for researchers, academia, biopharma industries, graduate and postgraduate students, Ph.D., and post-doctoral fellows working in the fields of toxicology/biosafety, and biomedical research.
Flow Sensing in Air and Water
by Horst Bleckmann Joachim Mogdans Sheryl L. CoombsIn this book, leading scientists in the fields of sensory biology, neuroscience, physics and engineering explore the basic operational principles and behavioral uses of flow sensing in animals and how they might be applied to engineering applications such as autonomous control of underwater or aerial vehicles. Although humans possess no flow-sensing abilities, countless aquatic (e. g. fish, cephalopods and seals), terrestrial (e. g. crickets and spiders) and aerial (e. g. bats) animals have flow sensing abilities that underlie remarkable behavioral feats. These include the ability to follow silent hydrodynamic trails long after the trailblazer has left the scene, to form hydrodynamic images of their environment in total darkness, and to swim or fly efficiently and effortlessly in the face of destabilizing currents and winds.
Flu Therapy: (A Storey Country Wisdom Bulletin A-266) (Storey Country Wisdom Bulletin Ser.)
by Elizabeth Wotton N.D.Since 1973, Storey's Country Wisdom Bulletins have offered practical, hands-on instructions designed to help readers master dozens of country living skills quickly and easily. There are now more than 170 titles in this series, and their remarkable popularity reflects the common desire of country and city dwellers alike to cultivate personal independence in everyday life.
Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It
by Gina KolataVeteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease.In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out.Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.
Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics
by Paul E. Smith Enrico Matteoli John P. O’ConnellThere are essentially two theories of solutions that can be considered exact: the McMillan-Mayer theory and Fluctuation Solution Theory (FST). The first is mostly limited to solutes at low concentrations, while FST has no such issue. It is an exact theory that can be applied to any stable solution regardless of the number of components and their co
Fluency Plus: Managing Fluency Disorders in Individuals With Multiple Diagnoses
by Kathleen Scaler ScottFluency disorders such as stuttering, cluttering, and atypical disfluency are often accompanied by concomitant speech and language disorders, as well as other disorders impacting and interacting with fluency. Despite this common presentation, there is little training for speech-language pathologists to confidently treat fluency disorders and concomitant disorders together. Fluency Plus: Managing Fluency Disorders in Individuals with Multiple Diagnoses fills this much-needed gap, providing a strong research base along with practical strategies and treatment activities to guide speech-language pathologists in managing clients with fluency and concomitant disorders.Dr. Kathleen Scaler Scott brings her years of clinical experience and her research in the areas of stuttering, cluttering and atypical disfluencies to Fluency Plus, designing it to act as both a textbook for students and a practical guide for the clinician. The comprehensive review of current definitions of fluency disorders and the evidence base for treatments will be of great help to students, while clinicians will appreciate the specific guidelines, strategies, and activities for managing fluency in concomitant disorders.After reviewing general principles and covering how executive functions relate to the management of these multiple concerns, the text addresses seven concomitant disorder areas the speech-language pathologist may encounter in practice. For each disorder category, an overview of potential fluency problems is provided, myths regarding treatment of fluency disorders in each population are debunked, and effective treatment activities are recommended.Some Concomitant Disorders Covered: Intellectual Disability Speech Sound Disorders (apraxia, phonological, articulation disorders) Learning Disabilities, Auditory Processing and Language Disorders Attention Deficit Hyperactivity Disorder Autism Spectrum Disorder Selective Mutism Fluency Plus: Managing Fluency Disorders in Individuals with Multiple Diagnoses helps close an education and training gap for students and clinicians alike by increasing their confidence, knowledge, and skills when dealing with fluency disorders and complex combinations of concomitant disorders.
Fluid Balance, Hydration, and Athletic Performance
by Flavia MeyerAthletes and nonathletes frequently consume too little water or fluids, affecting exercise performance as well as overall health. This book comprehensively reviews the aspects relating to body fluid balance, rehydration, and physical exercise. It provides background on body water balance and turnover, topics related to electrolyte balance, and sweating as the basis for thermoregulatory and fluid homeostasis during exercise. In addition, chapters cover body water balance evaluation and regulation; cardiovascular and metabolic responses to fluid imbalance; effects of dehydration on aerobic power, muscle strength, and cognitive function; fluid intake timing; and optimal beverage selection.
Fluid Mechanics for Cardiovascular Engineering: A Primer
by Gianni PedrizzettiThis book provides a guiding thread between the distant fields of fluid mechanics and clinical cardiology. Well rooted in the science of fluid dynamics, it drives the reader across progressively more realistic scenarios up to the complexity of routine medical applications. Based on the author’s 25 years of collaborations with cardiologists, it helps engineers learn communicating with clinicians, yet maintaining the rigor of scientific disciplines. This book starts with a description of the fundamental elements of fluid dynamics in large blood vessels. This is achieved by introducing a rigorous physical background accompanied by examples applied to the circulation, and by presenting classic and recent results related to the application of fluid dynamics to the cardiovascular physiology. It then explores more advanced topics for a physics-based understanding of phenomena effectively encountered in clinical cardiology. It stands as an ideal learning resource for physicists and engineers working in cardiovascular fluid dynamics, industry engineers working on biomedical/cardiovascular technology, and students in bio-fluid dynamics. Written with a concise style, this textbook is accessible to a broad readership, including students, physical scientists and engineers, offering an entry point into this multi-disciplinary field. It includes key concepts exemplified by illustrations using cutting-edge imaging, references to modelling and measurement technologies, and includes unique original insights.
Fluid Resuscitation: State of the Science for Treating Combat Casualties and Civilian Injuries
by Institute of MedicineHistorically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood loss--hemorrhage--is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties.In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research.The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.