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Functional Mitral and Tricuspid Regurgitation
by Kok Meng John ChanThis book covers in detail all aspects of functional mitral and tricuspid regurgitation, from its pathophysiology and natural history, to its assessment, medical and surgical treatment, and long term results. Functional Mitral and Tricuspid Regurgitation encompasses information and knowledge from a diverse background including cardiology, cardiac surgery and basic science. This is necessary for a full understanding of the subject in order to optimally manage patients with this condition.
Functional Movement Disorder: An Interdisciplinary Case-Based Approach (Current Clinical Neurology)
by Kathrin LaFaver Carine W. Maurer Timothy R. Nicholson David L. PerezThis book is a practical manual for clinical practitioners seeking to take an interdisciplinary and multidisciplinary approach to the diagnosis and management of functional movement disorder (FMD). It discusses case vignettes, reviews the diagnostic approach, provides an update on available treatments, highlights clinical pearls and details references for further reading.Organized into three parts, the book begins with a framework for conceptualizing FMD - including its historical context, the biopsychosocial model and an integrated neurologic-psychiatric perspective towards overcoming mind-body dualism. Part II then provides a comprehensive overview of different FMD presentations including tremor, dystonia, gait disorders, and limb weakness, as well as common non-motor issues such as pain and cognitive symptoms. The book concludes with chapters on updated practices in delivering the diagnosis, working with patients and care partners to achieve shared understanding of a complex condition, as well as an overview of evidence-based and evolving treatments. Supplemented with high-quality patient videos, Functional Movement Disorder is written for practicing neurologists, psychiatrists, psychologists, allied mental health professionals, and rehabilitation experts with an interest in learning more about diagnosis and management of FMD.
Functional Nanomaterials for Regenerative Tissue Medicines (Emerging Materials and Technologies)
by Mariappan RajanThis book covers nanomaterials in tissue engineering for regenerative therapies of heart, skin, eye, skeletal muscle, and the nervous system. The book emphasizes fundamental design concepts and emerging forms of nanomaterials in soft- and hard-tissue engineering. FEATURES Fills a gap in the literature related to the application of nanomaterials in hard- and soft-tissue regeneration, repair, and restructure Discusses a variety of applications, including cardiac, kidney, liver, bone, wound healing, artificial organs, and dental Presents advantages and limitations of various nanomaterials alongside future challenges Functional Nanomaterials for Regenerative Tissue Medicines is essential for academics and industry professionals working in tissue engineering, biomedicine, biopharmaceuticals, and nanotechnology. It is primarily intended for materials researchers (to develop the platforms related to tissue regeneration) as well as clinicians (to learn and apply nanomaterials in their practice) and industrial scientists (to develop commercial blood substitute products).
Functional Neuroimaging in Exercise and Sport Sciences
by Charles H. Hillman Henning Boecker Lukas Scheef Heiko K. StrüderRegular physical exercise is associated with substantial health benefits. Recent evidence not only holds for cardiovascular effects promoting "physical health", but also for the central nervous system believed to promote "brain health". Moderate physical exercise has been found to improve learning, memory, and attentional processing, with recent research indicating that neuroprotective mechanisms and associated plasticity in brain structure and function also benefit. Physical exercise is also known to induce a range of acute or sustained psychophysiological effects, among these mood elevation, stress reduction, anxiolysis, and hypoalgesia. Today, modern functional neuroimaging techniques afford direct measurement of the acute and chronic relation of physical exercise on the human brain, as well as the correlation of the derived physiological in vivo signals with behavioral outcomes recorded during and after exercise. A wide range of imaging techniques have been applied to human exercise research, ranging from electroencephalography (EEG), magnetoencephalography (MEG), near infrared spectroscopy (NIRS), magnetic resonance imaging (MRI) to positron emission tomography (PET). All of these imaging methods provide distinct information, and they differ considerably in terms of spatial and temporal resolution, availability, cost, and associated risks. However, from a "multimodal imaging" perspective, neuroimaging provides an unprecedented potential to unravel the neurobiology of human exercise, covering a wide spectrum ranging from structural plasticity in gray and white matter, network dynamics, global and regional perfusion, evoked neuronal responses to the quantification of neurotransmitter release. The aim of this book is to provide the current state of the human neuroimaging literature in the emerging field of the neurobiological exercise sciences and to outline future applications and directions of research.
Functional Neuroimaging in Whiplash Injury: New Approaches
by Andreas OtteThis book, now in its second, completely revised and updated edition, offers a critical approach to the challenging interpretation of the latest research data obtained using functional neuroimaging in whiplash injury. Such a comprehensive guide to recent and current international research in the field is more necessary than ever, given that the confusion regarding the condition and the medicolegal discussions surrounding it have increased further despite the publication of much literature on the subject. In recent decades especially the functional imaging methods – such as single-photon emission tomography, positron emission tomography, functional MRI, and hybrid techniques – have demonstrated a variety of significant brain alterations. Functional Neuroimaging in Whiplash Injury - New Approaches covers all aspects, including the imaging tools themselves, the various methods of image analysis, different atlas systems, and diagnostic and clinical aspects. The book will help physicians, patients and their relatives and friends, and others to understand this condition as a disease.
Functional Neuroimaging in Whiplash Injury: New Approaches
by Andreas OtteThis book, now in its third, completely revised and updated edition, offers a critical approach to the challenging interpretation of the latest research data obtained using functional neuroimaging in whiplash injury. Such a comprehensive guide to recent and current international research in the field is more necessary than ever, given that the confusion regarding the condition and the medicolegal discussions surrounding it have increased further despite the publication of much literature on the subject. In recent decades especially the functional imaging methods – such as single-photon emission tomography, positron emission tomography, functional MRI, and hybrid techniques – have demonstrated a variety of significant brain alterations. Functional Neuroimaging in Whiplash Injury - New Approaches covers all aspects, including the imaging tools themselves and the various methods of image analysis. Details on biomechanics, including the finite element method and facts on historical whiplash experiments and crash tests have now been added to this new edition. The book will continue to help physicians, patients and their relatives and friends, and others to understand this condition as a disease.
Functional Neuroimaging: A Clinical Approach
by Andrei HolodnyThe first text designed specifically with clinical practitioners in mind, Functional Neuroimaging demonstrates the clinical application and utilization of functional neuroradiology for early diagnosis, neurological decision-making, and assessing response to cancer therapy. Edited by the Founding President of American Society of Functional Neuroradi
Functional Neuroradiology
by Feroze B. Mohamed Scott H. Faro John T. Ulmer Meng LawFunctional Neuroradiology: Principles and Clinical Applications, is a follow-up to Faro and Mohamed's groundbreaking work, Functional (BOLD)MRI: Basic Principles and Clinical Applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divided into 9 major sections, including: Physical principles of all key functional techniques, Lesion characterization using Diffusion, Perfusion, Permeability, MR spectroscopy, and Positron Emission Tomography, an overview of BOLD fMRI physical principles and key concepts, including scanning methodologies, experimental research design, data analysis, and functional connectivity, Eloquent Cortex and White matter localization using BOLD fMRI and Diffusion Tensor Imaging, Clinical applications of BOLD fMRI in Neurosurgery, Neurology, Psychiatry, Neuropsychology, and Neuropharmacology, Multi-modality functional Neuroradiology, Beyond Proton Imaging, Functional spine and CSF imaging, a full-color Neuroanatomical Brain atlas of eloquent cortex and key white matter tracts and BOLD fMRI paradigms. By offering readers a complete overview of functional imaging modalities and techniques currently used in patient diagnosis and management, as well as emerging technology, Functional Neuroradiology is a vital information source for physicians and cognitive neuroscientists involved in daily practice and research.
Functional Neuroradiology: Principles and Clinical Applications
by Feroze B. Mohamed Scott H. FaroThis new edition fully updates and expands Faro and Mohamed’s Functional Neuroradiology, a gold standard, comprehensive introduction to the state-of-the-art functional imaging in neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divided into 12 major sections, including: Diffusion and Perfusion Imaging, Magnetic Resonance Spectroscopy and Chemical Exchange Saturation Transfer Imaging, Multi-Modality Functional Neuroradiology, BOLD Functional MRI, Diffusion Tensor Imaging, Presurgical Brain Tumor Mapping, Emerging neuroimaging techniques, Functional Spine and Hydrocephalus imaging, and Neuroanatomical Gray and White matter Brain Atlases. This second edition is fully updated throughout and includes more than 15 new chapters on topics such as: Brain tumor Radiogenomics, CNS Tumor Surveillance and Functional MR Perfusion Imaging, CNS Machine Learning, Focused Ultrasound therapy, TBI Sports Related Injury, and CNS Lymphatic system. By offering readers a complete overview of functional imaging modalities and techniques currently used in patient diagnosis and management, as well as emerging technology, Functional Neuroradiology is a vital information source for physicians and cognitive neuroscientists involved in daily practice and research.
Functional Nucleic Acid Based Biosensors for Food Safety Detection
by Yunbo LuoThis book highlights the development of a functional nucleic acid based biosensor detection method in the context of food safety. Although there have been major advances in food processing technology in both developed and developing countries, food safety assurance systems are generally becoming more stringent, in response to growing (both real and perceived) food safety problems. These problems are due in part to foodborne microorganisms, heavy metals, and small chemical molecules (biological toxins, pesticide residues, and veterinary drug residues), etc. In addition, the nucleic acid biomarkers (DNA methylation, microRNA, and circRNA) induced by these risk factors are also closely related to food safety. Accordingly, this book offers a brief guide to targets and strategies in functional nucleic acid based biosensors for food safety detection. Divided into several chapters that focus on various respective targets, it will be a valuable resource for students and researchers in the fields of biosensor detection, food science etc.
Functional Nucleic Acids Detection in Food Safety
by Wentao XuThis book focuses on the development of functional nucleic acids and their applications of molecular detection methods in the context of food safety. The book has been expanded to 24 chapters based on the first edition including five newly-added chapters, of which involving the systematic introduction of currently-fashionable functional nucleic acid elements, the basic mechanism of diverse amplification technologies, and the novel design strategies of detection methods from the latest research findings for food safety. Offering a comprehensive overview of nucleic acids detection method in food safety for professionals and members of the public interested in this area.
Functional Ophthalmic Disorders
by William Morris Thomas O'Donnell Robert Enzenauer Jill MontreyThis is a practical manual for diagnostic testing, focusing on the historical and contemporary research on functional disorders in general, and functional visual disorders in particular. Functional Ophthalmic Disorders: Ocular Malingering and Visual Hysteria is a how-to manual that is written for the practicing ophthalmologist and optometrist, complete with color photos that allow the reader to see pictures of select diseases. In addition to the photos, videos are provided online to illustrate the various tests and possible results conducted on a mock patient to assist in the differential diagnosis. Written and edited by leaders in the field, some of the topics covered include history of functional disorders, ophthalmologic examination in malingering and techniques and tests for functional and simulated defects.
Functional Performance in Older Adults (Third Edition)
by Bette R. Bonder Vanina Dal Bello-Haas Marilyn B. Wagner Bette Bonder Vanina Bello-Haas"The contributors represent diverse disciplines, however their messages create a coherent, integrated work of universal interest and application. I highly recommend the use of this text for allied health students who are studying geriatric rehabilitation and for clinicians who wish to renew their knowledge. "--Carole Knight, MEd, OTR/L, Occupational Therapy in Health Care Journal, Volume 16, Number 2/3 February 2003, review of the 2nd Edition. The ideal resource for rehabilitation professionals who are working with or preparing to work with older adults! It describes the normal aging process, illustrates how health and social factors can impede an aging person's abilities, and demonstrates how to develop mechanisms for maximizing the well-being of older adults.
Functional Protein Microarrays in Drug Discovery (Drug Discovery Series)
by Paul F. PredkiAn ideal text for biotechnologists, protein chemists, and biochemists, Functional Protein Microarrays in Drug Discovery explores all aspects of functional protein microarrays, including basic principles, methods, and applications. The book discusses the generation of functional protein content and describes both standard and state-of-the-art fabrication methods. It reviews current and next generation approaches to assay detection and presents a wide range of applications, from biomolecular interaction discovery and characterization to immune response profiling. The book also addresses several fundamental computational issues, bioinformatics and data analysis.
Functional Reconstruction of the Female Urinary Tract and Gynaeco-Urology
by Christopher R. Chapple Nadir I. Osman Richard T. Turner-WarwickOverview of female urological reconstructive surgery with illustrations, photographs, and diagrams spanning all surgical procedures in the field Functional Reconstruction of the Female Urinary Tract and Gynaeco-Urology is a comprehensive reference text encompassing the entire field of reconstructive female urology, delivering in-depth knowledge of structure, function, and dysfunction of the female urinary tract and imparting a thorough understanding of the principles of urodynamics related to lower urinary tract reconstruction. In this Second Edition, authors Christopher Chapple and Nadir Osman have retained many of the original descriptions from the first edition in tribute to the work of Richard Turner-Warwick, who is considered the father of functional urological reconstruction in the United Kingdom. Where appropriate, the text and comments have been updated to reflect developments in the field. In Functional Reconstruction of the Female Urinary Tract and Gynaeco-Urology, readers will find: Detailed descriptions of surgical principles and procedures with 1600 colour illustrations based on original drawings by Paul Richardson.“Tricks of the trade”, “pearls of wisdom”, and other original concepts related to the field.The principles, art, and philosophy of surgery, as well as details on instruments and surgical access to the urinary tract.Information on surgical management of conditions that a specialist surgeon working in this field will encounter in their clinical practice. Functional Reconstruction of the Female Urinary Tract and Gynaeco-Urology is an essential one-of-a-kind reference for surgeons at any level of practice, regardless of training or experience. The text is also valuable for advanced students in related programmes of study.
Functional Respiratory Disorders
by Ran D AnbarMany patients with pulmonary complaints fail to improve despite physicians' best efforts. Sometimes, we ascribe this failure to lack of adherence with therapy, or to the severity of the condition. What we often fail to appreciate, however, is that sometimes the lack of improvement can be explained by the patients' psychological states. The first section of Functional Respiratory Disorders: When Respiratory Symptoms Do Not Respond to Pulmonary Treatment will help clinicians recognize functional respiratory symptoms that can arise as a result of both organic and psychological causes. The second section of this book provides detailed discussions of such disorders, links to video examples of laryngoscopic evaluation of patients with vocal cord issues, case studies and quizzes. Examples and exercises that should strengthen the clinician's confidence in identifying and treating these functional conditions are also provided. Finally, the third section of the book will help the clinician differentiate the patients for whom referral to a mental health provider is mandatory from those for whom other approaches may be useful. For the latter group, the book teaches clinicians to empower themselves by learning how to incorporate various therapies for functional disorders into their practice, including biofeedback, breathing techniques, basic cognitive behavioral therapy techniques, and hypnosis. Links are provided to instructive video examples of biofeedback, hypnosis, and speech therapy. Practical strategies for obtaining training in these modalities are provided in the appendix. Functional Respiratory Disorders: When Respiratory Symptoms Do Not Respond to Pulmonary Treatment is an important new book that will help clinicians consider the possible impact of functional contributions to the clinical presentation of every patient with respiratory symptoms and identified respiratory disease.
Functional Selectivity of G Protein-Coupled Receptor Ligands
by Kim NeveFunctional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, and for the design of experiments to characterize receptor function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessible and authoritative, Functional Selectivity of G Protein-Coupled Receptors is a valuable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function.
Functional Smart Nanomaterials and Their Theranostics Approaches (Smart Nanomaterials Technology)
by Rajendra Prasad Azamal Husen Alle Madhusudhan Shiv Dutt PurohitThis book covers a number of engineered nanotheranostics platforms and nanomedicines applications of FDA-approved medicines for early-stage diagnosis and treatment of cancer. The book focuses on (i) the basic design and bioengineering of safe medicines, (ii) physicochemical understanding of surface engineered medicines and their characteristics, (iii) various examples for site-specific bioimaging and multimode therapies, (iv) stimuli-responsive approaches for targeted drug delivery applications, (v) targeted therapeutics approaches for cancer cells or solid tumor ablations, (vi) targeted mechanisms of administrative biomedicines, (vii) impact of surface modification or engineering of biomedicines for site-selective tumor binding ability, and (vii) requirements for clinical trials and FDA approval. The content of this book appeal to readers who are interested in recent developments of FDA-approved cost-effective rapid cancer imaging and therapeutic platforms.
Functional Somatic Symptoms in Children and Adolescents: A Stress-System Approach to Assessment and Treatment (Palgrave Texts in Counselling and Psychotherapy)
by Stephen Scher Kasia Kozlowska Helene HelgelandThis open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.
Functional Symptoms in Pediatric Disease: A Clinical Guide
by Ran D. AnbarMany children with medical conditions fail to improve despite physicians' best efforts. Sometimes, we ascribe this failure to lack of adherence to therapy or to the severity of the condition. What we often fail to appreciate, however is that sometimes the lack of improvement can be explained by the patients' psychological states. The first section of Functional Symptoms in Pediatric Disease: A Clinical Guide teaches children's health care providers to recognize functional symptoms that can complicate organic disease as well as symptoms that are believed to be purely functional in origin. Literature reviews, case studies and quizzes are provided in each chapter, with video demonstrations included in some of the chapters. The second section of the book will help clinicians differentiate the patients for whom referral to a mental health provider is mandatory from those for whom other approaches may be useful. For the latter group, the book teaches clinicians to empower themselves by learning how to incorporate various therapies for functional disorders into their practice, including biofeedback, basic cognitive behavioral therapy techniques, hypnosis, acupressure, yoga and meditation. Practical strategies for obtaining training in these modalities are provided in the appendix. Useful for practicing clinicians including pediatricians, family practitioners, pediatric subspecialists, child psychiatrists, psychologists, other mental health care providers and practitioners of alternative and complementary medicine, Functional Symptoms in Pediatric Disease: A Clinical Guide is an important new book that will help children's health care providers consider the possible impact of functional contributions to the clinical presentation of their patients.
Functional Urologic Surgery in Neurogenic and Oncologic Diseases
by Antonio Carbone Giovanni Palleschi Antonio Luigi Pastore Aurel MessasThis book offers a comprehensive guide to state-of-the-art techniques in functional urologic surgery that minimize functional damage to the urinary tract and are of particular value in patients with oncologic or neurogenic diseases. It describes the main minimally invasive surgical techniques currently available step by step, while also offering guidance on indications and how to select appropriate surgical devices to achieve specific oncological and functional outcomes. Further, the book presents data from relevant case series, documenting the favorable functional and oncologic results achieved with these techniques and devices as well as the low associated morbidity and positive impacts on quality of life. Lastly, it offers advice on preoperative assessment and postoperative care, and presents specific diagnostic algorithms of value in daily clinical practice. The contributing authors represent an international mix of respected experts carefully selected for their knowledge of the topics discussed.
Functional Vision: A Practitioner's Guide To Evaluation And Intervention
by Amanda Hall LueckAn essential tool for anyone working in the area of low vision, Functional Vision presents a systematic, comprehensive, integrated approach to assessing an individuals functional vision and delivering the appropriate services determined by the assessment results. Based on groundbreaking work by distinguished professionals who have developed the specific principles and procedures for helping people of all ages with low vision, including those with multiple disabilities, the text explains how to link intervention to assessment findings and to teach compensatory skills through everyday activities at school, work, home, and in the community. This detailed and practical guide provides case examples, charts, figures, and sample forms that enable practitioners to apply expert methods in their work with clients
Functional and Motility Disorders of the Gastrointestinal Tract
by Brian E. Lacy Michael D. Crowell John K. DibaiseThis volume covers the myriad of functional and motility gastrointestinal disorders in a comprehensive manner. The book is divided into seven major sections, with each section beginning with a brief case presentation highlighting the specific disorder to be reviewed. Appropriate criteria is highlighted, followed by a brief review on the epidemiology, etiology, pathophysiology, diagnosis and treatment of each specific disorder. 2-3 key teaching "pearls", test questions and key references are also provided for each chapter. The book is organized so that each chapter can stand on its own and be used as a quick reference source in the clinic. Alternatively, it can be read cover to cover as an authoritative textbook on gastrointestinal functional and motility disorders. Written by international experts in the field of motility disorders, Functional and Motility Disorders of the Gastrointestinal Tract: A Case Study Approach is an invaluable resource for experienced physicians, students, residents, fellows, nurse practitioners and physician assistants.
Functional and Neural Mechanisms of Interval Timing (Frontiers in Neuroscience)
by Warren H. MeekUnderstanding temporal integration by the brain is expected to be among the premier topics to unite systems, cellular, computational, and cognitive neuroscience over the next decade. The phenomenon has been studied in humans and animals, yet until now, there has been no publication to successfully bring together the latest information gathered from
Functionalized Materials Applications in Biomedicine
by Petrica Vizureanu Andrei Victor Sandu Seiji Yamaguchi Madalina Simona Baltatu Gültekin Göller Camilo Zamora-Ledezma Iulian-Vasile AntoniacThis book offers an in-depth exploration of biomaterials with a primary focus on recent developments. It begins by providing a comprehensive background on the basic principles of biomaterials, followed by the synthesis, properties, and performance of various biomaterials. Subsequent chapters discuss topics such as biocompatibility, the interaction of biomaterials with the human body, and the role of biomaterials in regenerative medicine. It also addresses the technological advancements in biomaterials, novel fabrication methods, and surface modification techniques backed by case studies.Features: Presents the latest advancements in biomaterials, including novel fabrication methods, innovative materials, and groundbreaking applications in medical devices and regenerative medicine Offers a holistic view of the biomaterials field, bridging various disciplines such as biology, chemistry, materials science, and medicine Illustrates practical applications of biomaterials in tissue engineering, drug delivery systems, and medical imaging Delves into the ethical, regulatory, and commercial dimensions of biomaterials Includes detailed case studies on topics such as thermal properties, corrosion resistance, and industrial coatings This book is aimed at researchers and graduate students of bioengineering, biomaterials, and materials science.