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Handbook Methods For Oxygen Radical Research

by Robert A. Greenwald

This volume is divided into five sections. Section I deals with preparative methodology for isolation and purification of the components of the oxy radical experimental systems use most frequently, including all three forms of SOD and several other important scavengers. Section II provides the experimenter with a choice of a dozen oxy radical generating systems which can be used for testing of scavengers or for evaluation of the effects of oxy radicals on target tissues. The reader will note that in this section, as well as in most of the rest of the volume, the orientation is primarily biochemical, biologic, and medical, rather than pure chemistry or pure physics. Nevertheless, the techniques are widely applicable to a variety of disciplines.

Handbook Of Adolescent Inpatient Psychiatric Treatment

by Harinder S. Ghuman Richard M. Sarles

First published in 1994. Routledge is an imprint of Taylor & Francis, an informa company.

Handbook Of Child And Adolescent Outpatient, Day Treatment A

by Harinder S. Ghuman Richard M. Sarles

In the past few years, there has been a major shift in the mental health care of child and adolescents from inpatient care to non-hospital community ambulatory settings. Economic pressures have primarily driven this change in service delivery. Insurance companies and managed care organizations have not only restricted access to hospitalization and limited length of stays but additionally have sharply reduced reimbursements for treatments. State and federal policies for inpatient treatment and reimbursement have followed similar trends. As a result, mental health planners have attempted to develop programs to deal with this trend of restricted inpatient care shifting treatment of children and adolescents to home and community settings. Some of these new programs are well planned and others are hastily planned and implemented. The pitfall to this community approach is that there is a population of chronically disturbed children and adolescents, and highly stressed parents often lacking adequate personal and family resource who may not respond to these new less restrictive, less costly community approaches which potentially may lead to an unsafe and dangerous situation for the child, adolescent, family and the community.With this in mind, the purpose of this book is to provide comprehensive and up-to-date information regarding child and adolescent outpatient, day treatment and community psychiatry. The emphasis of this book is to provide practical knowledge through clinical case illustrations and to explain various strategies in a detailed fashion.

Handbook Of Clinical Psychopharmacology For Therapists

by John D. Preston John H. O'Neal Mary C. Talaga

This book is intended primarily for mental health professionals and those in graduate training in psychology, social work, psychiatric nursing, and counseling. The professional goal of most readers will be to provide services that aim to reduce emotional pain, to promote psychological growth and healing

Handbook Of Clinical Psychopharmacology For Therapists

by John D. Preston John H. O'Neal Mary C. Talaga

A comprehensive professional resource for mental health treatment―now in a fully revised and updated ninth editionThe Handbook of Clinical Psychopharmacology for Therapists is the gold standard for mental health clinicians looking for clear, reliable information about the pharmacological treatment of mental health issues. Organized by disorder and, within each disorder, by medication, this book is designed to familiarize clinicians and students with the basic terminology and models of psychopharmacology. This fully revised and updated ninth edition provides essential information on new medications and treatment options and includes the latest research on side effects, contraindications, and efficacy of all major medications prescribed for mental health disorders. You’ll also find new chapters on sleep disorders and experimental treatments, updated information on child and adolescent psychopharmacology and the latest best practices for treating pregnant and breastfeeding patients and patients with substance use disorders.This handbook makes it simple to: get the facts about drug interactions and side effects; find out how medications affect adults, children, and adolescents differently; learn how different cultures view medical treatment, vital information for anyone who treats clients from a variety of backgrounds; and discontinue medication safely when needed.This essential guide to psychopharmacology has been adopted as a textbook at universities nationwide and is an important resource for every therapist’s library.

Handbook Of Good Psychiatric Management For Borderline Personality Disorder

by John G. Gunderson Paul S. Links

The Handbook of Good Psychiatric Management for Borderline Personality Disorder teaches clinicians what to do and how to do it, as well as what not to do and how to avoid it. The author, a renowned researcher and clinician, has developed a new evidence-based treatment, Good Psychiatric Management (GPM) that comfortably utilizes cognitive, behavioral, and psychodynamic interventions that are practical and simple to implement. Because psychoeducation is an important component of GPM, the book teaches clinicians how to educate their patients about BPD, including the role of genetics and the expected course of the disease. This approach offers advantages both to practitioners, who become more adept at honest communication, and to patients, who are encouraged to have realistic hopes and to focus on strategies for coping with BPD in daily life.

Handbook Of Nursing Diagnosis 14th Edition

by Lynda Juall Carpenito

The ideal quick reference, this handbook offers practical guidance on nursing diagnoses and associated care. Sections cover Nursing Diagnoses, Health Promotion/Wellness Nursing Diagnoses, and Diagnostic Clusters--medical conditions with relevant collaborative problems and nursing diagnoses. NEW! The newest nursing diagnoses approved by NANDA International for 2012-2014 are included in this edition.

Handbook Of Stress, Trauma, And The Family (Routledge Psychosocial Stress)

by Don R. Catherall

The Handbook of Stress, Trauma, and the Family is broken down into three sections, compiling research, theory and practice. The first section focuses on how traumatic stress affects intimate others, what familial characteristics affect individual susceptibility to trauma, as well as evaluation of the effectiveness of various interventions. The section on theory explores concepts of stress and intrapsychic processes underlying the intergenerational transmission of trauma, addressesing how families can buffer or enhance anxiety. The final section, entitled practice, covers assessment (presenting both the Circumplex Model and Bowenian family theory models), treatment models and treatment formats for specific populations. The major family treatment models applicable to stress and trauma are discussed, including contextual, object relations, emotionally focused and critical interaction therapy.

Handbook Positive Health in Primary Care: The Dutch Example

by Machteld Huber Hans Peter Jung Karolien van den Brekel-Dijkstra

Increasing numbers of general practitioners are discovering the benefits of working with Positive Health. It helps to talk with patients in a different way, with a focus on possibilities rather than on the impossibilities related to a particular health problem. This is good for the patient. And for the general practitioner. But how do we apply Positive Health? This handbook provides useful tools!The book is full of tips, tells the story of how the concept was first developed and gives practical examples. It explains the underlying scientific basis of Positive Health — with a clear emphasis on what is meaningful to patients. And, above all, this book invites you to start working with Positive Health on various levels — in your consulting room, your practice and in the local community. Because cooperation and combined effort are key. You will experience how Positive Health seamlessly fits the core values and challenges of all aspects of primary care. The handbook is intended for all primary care professionals as well as those who are still in training. It describes the Dutch health care system and the experiences related to inspiration, implementation and the anchoring of the Positive Health concept into this system. The publication is indispensable for anyone who wants to provide meaningful primary care using the Positive Health concept. ‘When I heard about Positive Health and the spider web, I felt that it gave us a much wanted tool to empower our patients and the community.’ Elínborg Bárðardóttir, general practitioner & programme director primary care training, Primary Healthcare in Iceland

Handbook for Chemical Process Industries

by Himanshu J Patel

Chemical processing industry plays a pivotal role in the economy of a country, as chemicals are required in every sphere of our lives. This book covers chemical processing of dyes, pigments, drugs and pharmaceutical products, fermented products, agrochemicals, explosives, polymers, Period II and III chemicals, chemicals, sugar, coatings, starches, soaps and detergents, paper, pulp, glass, and cement. It includes sources of natural materials, collection process, purification, and extraction of different chemicals from natural materials like petroleum, coal and ores from the Earth. It includes manufacturing details of C1 to C4 and aromatic compounds obtained from natural materials. The book covers both traditional and modern sectors of the chemical processing industry. It provides knowledge on the properties of the chemical and manufacturing process (such as raw materials, chemical reactions, quantitative requirement, flow sheet diagram, procedure) and its uses. The book is based on the author's expertise and has been developed with an awareness of the quantitative requirement for manufacturing chemicals. Data has been collected from industry, thus it will be useful to industry personnel, research groups, academicians and institutional organizations.

Handbook for Chemical Process Research and Development

by Wenyi Zhao

The Handbook for Chemical Process Research and Development focuses on developing processes for chemical and pharmaceutical industries. Forty years ago there were few process research and development activities in the pharmaceutical industry, partially due to the simplicity of the drug molecules. However, with the increasing structural complexity, especially the introduction of chiral centers into the drug molecules and strict regulations set by the EMA and FDA, process R&D has become one of the critical departments for pharmaceutical companies. This book assists with the key responsibility of process chemists to develop chemical processes for manufacturing pharmaceutical intermediates and final drug substances for clinical studies and commercial production.

Handbook for Chemical Process Research and Development, Second Edition

by Wenyi Zhao

This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies. Features: This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner. Promotes an industrial mindset concerning safety and commercial viability when developing methods. The author discusses development strategies with case studies and experimental procedures. Focuses on mechanism-guided process development which provides readers with practical strategies and approaches. Addresses more common process issues such as safety, cost, robustness, and environmental impact. This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.

Handbook for Clinical Investigators

by Christopher Kirkpatrick

This text is aimed at potential clinical investigators usually physicians, especialy those thinking about doing clinical trials to evaluate new drugs - mostly sponsored by pharmaceutical companies.

Handbook for Clinical Trials of Imaging and Image-Guided Interventions

by Nancy A. Obuchowski G. Scott Gazelle

Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual 'Clinical Trials Methodology Workshop' for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.

Handbook for Culturally Competent Care

by Larry D. Purnell Eric A. Fenkl

This concise, easy-to-read book tackles the potentially awkward subject of culture in a direct, non-intimidating style. It prepares all health professionals in any clinical setting to conduct thorough assessments of individual from culturally specific population groups, making it especially valuable in today's team-oriented healthcare environment. The book is suitable for healthcare workers in all fields, particularly nurses who interact with the patients 24 hours a day, every day of the week. Based on the Purnell Model for Cultural Competence, it explores 26 different cultures and the issues that healthcare professionals need to be sensitive to. For each group, the book includes an overview of heritage, communication styles, family roles and organization, workforce issues, biocultural ecology, high-risk health behaviors, nutrition, pregnancy and child bearing, death rituals, spirituality, healthcare practices, and the views of healthcare providers. It also discusses the variant characteristics of culture that determine the diversity of values, beliefs, and practices in an individual's cultural heritage in order to help prevent stereotyping. These characteristics include age, generation, nationality, race, color, gender, religion, educational status, socioeconomic status, occupation, military status, political beliefs, urban versus rural residence, enclave identity, marital status, parental status, physical characteristics, sexual orientation, gender issues, health literacy, and reasons for migration. Each chapter offers specific instructions, guidelines, tips, intervention strategies, and approaches specific to a particular cultural population.

Handbook for Culturally Competent Care

by Larry D. Purnell Eric A. Fenkl

The second edition of this incisive book, based on the Purnell Model for Cultural Competence, addresses the potentially challenging topic of culture in a forthright style. It is a valuable resource in today's team-based healthcare environment, preparing health professionals, regardless of setting, to conduct in-depth assessments of individuals and families from culturally specific population groups. This book will appeal to all healthcare workers in all fields, and it is particularly suitable for nurses interacting with patients in very diverse settings. This book delves into 32 different cultures and areas of support common to all individuals and families that health professionals must recognize and consider. African American, American Indian, Brazilian, Cuban, Chinese, Korean and Filipino, but also Arab, Hindu or Haitian, as well as many European heritages are examined among others. Brand new chapters explore Greek, Italian, Jamaican, Thai, and Ukrainian heritages. For each culture, chapters detail communication styles, family roles, workforce issues, biocultural ecology and high-risk health behaviours. Also discussed are nutrition, pregnancy and child bearing, death rituals, spirituality, healthcare practices, and the perceptions of traditional, magico-religious, and bio-medical healthcare providers. Culture’s characteristics - such as age, generation, gender, religion, educational/marital/parental/socioeconomic or even military status, but also political beliefs, physical characteristics, sexual orientation or gender issues - determining the diversity of values, beliefs, and practices in an individual's cultural heritage in order to help prevent stereotyping are discussed. At the end of each chapter, readers are provided with specific instructions, guidelines, tips, intervention strategies, and approaches specific to a particular cultural population. Additionally, reflective exercises help the reader reinforce the concepts presented in each chapter. For this second edition, most of the chapters are authored by individuals who either identify with the culture being addressed in the chapter or have personal knowledge of the culture via life experiences.

Handbook for Health Care Ethics Committees

by Jeffrey Blustein Linda Farber Post

How can dedicated ethics committees members fulfill their complex roles as moral analysts, policy reviewers, and clinical consultants?The Joint Commission (TJC) accredits and certifies more than 19,000 health care organizations in the United States, including hospitals, nursing homes, and home care agencies. Each organization must have a standing health care ethics committee to maintain its status. These interdisciplinary committees are composed of physicians, nurses, attorneys, ethicists, administrators, and interested citizens. Their main function is to review and provide resolutions for specific, individual patient care problems. Many of these committees are well meaning but may lack the information, experience, skills, and formal background in bioethics needed to adequately negotiate the complex ethical issues that arise in clinical and organizational settings.Handbook for Health Care Ethics Committees was the first book of its kind to address the myriad responsibilities faced by ethics committees, including education, case consultation, and policy development. Adopting an accessible tone and using a case study format, the authors explore serious issues involving informed consent and refusal, decision making and decisional capacity, truth telling, the end of life, palliative care, justice in and access to health care services, and organizational ethics.The authors have thoroughly updated the content and expanded their focus in the second edition to include ethics committees in other clinical settings, such as long-term care facilities, small community hospitals, rehabilitation centers, and hospices. They have added three new chapters that address reproduction, disability, and the special needs of the elder population, and they provide additional specialized policies and procedures on the book’s website. This guide is an essential resource for all health care ethics committee members.

Handbook for Health Care Ethics Committees

by Jeffrey Blustein Linda Farber Post

How can dedicated health care ethics committees increase their effectiveness and demonstrate their value as essential moral resources for their organizations?Among the most effective and increasingly valued resources in the health care decision-making process is the institutional ethics committee. The Joint Commission (TJC) accredits and certifies more than 19,000 health care organizations in the United States, including hospitals, nursing homes, and home care agencies. As a condition of accreditation, TJC requires health care organizations to have available a standing multidisciplinary ethics committee, composed of physicians, nurses, attorneys, ethicists, administrators, and interested lay citizens. Many of these committees are well meaning but may lack the information, experience, skills, and formal background in bioethics needed to effectively address the range and complexity of the ethical issues that arise in clinical and organizational settings.Handbook for Health Care Ethics Committees was conceived in 2007 to address the myriad responsibilities assumed by ethics committees. Using sample cases and accessible language, Linda Farber Post and Jeffrey Blustein explored applied bioethics, including informed consent and refusal, decision making and decisional capacity, truth telling, care at the beginning and end of life, palliation, justice in and access to health care services, and organizational ethics.In the third edition, Post and Blustein have thoroughly updated and reorganized the content and expanded the scope of the material, with special attention to changes in the health care landscape since the second edition was published in 2015. They also focus on communication between and among patients, care providers, and families, the demands of professionalism, the essential role that ethics committees can and should play, and how their effectiveness and value can be assessed. An entirely new chapter examines research ethics. The book also addresses the challenging ethical issues raised by the ongoing COVID-19 pandemic. This guide remains an essential resource for all health care ethics committee and their members.

Handbook for Principles and Practice of Gynecologic Oncology

by Douglas A. Levine Lillie Lin Stephanie Gaillard

Sized to fit in your pocket for quick reference, Handbook for Principles and Practice of Gynecologic Oncology, 3rd Edition, is packed with the essential information you need on the diagnosis and management of gynecologic cancers. Now in full color for the first time, this bestselling handbook features coverage of the most recent developments in the field, clear and concise data that support treatment recommendations, and numerous algorithms and tables throughout. Fellows, residents, and specialist trainees will benefit from authoritative coverage in an easily accessible format.

Handbook for Venous Thromboembolism

by Gregory Piazza Benjamin Hohlfelder Samuel Z. Goldhaber

​This book has been developed over numerous iterations within the Brigham and Women's Hospital to provide the most critical information for trainees and physicians, and thus it represents a truly practical guidebook for anyone who needs the key information on the diagnosis, management and prevention of venous thromboembolism. Specific areas of focus include understanding the risk factors for VTE and the role of the right ventricle in PE pathophysiology. Efficient algorithms for diagnosis and exclusion of DVT and PE are emphasized. An state-of-the-art review of current techniques for the management of high risk VTE, including submassive and massive PE, is presented. The novel oral anticoagulants are revolutionizing the way VTE is treated and are covered in detail. ​

Handbook of 200 Medicinal Plants: A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications

by Shahid Akbar

This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.

Handbook of 3D Printing in Biomedical Applications

by R. A. Ilyas A. N. Aufa Mohamad Zaki Hassan

3D printing is a promising fabrication technique capable of creating objects with precise structures and shapes based on 3D model data, allowing for versatile alterations and production of intricate shapes while also reducing the consumption of feedstock, particularly crucial in the cost-sensitive realm of medicine. In the biomedical sphere the use of 3D printing spans various applications, from artificial organs to sensors and orthopedic implants. This handbook explores the transformative role of technology in healthcare, focusing on materials, design, and innovation. It covers diverse applications like prosthetics, devices, tissue engineering, and medicine. This comprehensive resource highlights cutting-edge advancements, ethical considerations, and future trends, offering insights for researchers, professionals, and students. Explores the latest advances, technologies, and practical applications of additive manufacturing in biomedical engineering, including its impact on tissue engineering, drug delivery systems, regenerative medicine, and orthodontics Covers polymer 3D bioprinting techniques and advanced materials pivotal for successful biomedical implants in clinical settings Discusses the integration of smart materials and their applications including point-of-care solutions Encompasses various facets of medical technology, including diagnostic instruments, therapeutic devices, tissue engineering, and regenerative medicine Examines both in vivo and in vitro studies related to 3D printing, unraveling their significance and implications in various contexts Considers challenges and future perspectives With its comprehensive approach, this handbook serves as the definitive resource for researchers, practitioners, and advanced students, fostering a deeper appreciation and understanding of the transformative power of 3D printing in shaping the future of biomedical engineering.

Handbook of AI and Data Sciences for Sleep Disorders (Springer Optimization and Its Applications #216)

by Panos M. Pardalos Richard B. Berry Xiaochen Xian

The rise of lifestyle changes resulting from constant connectivity, irregular work schedules, heightened stress, and disruptive sleep patterns, have contributed to increasing insomnia rates. Exacerbated by the COVID-19 pandemic, sleep disorders are more prevalent than ever. This handbook offers a comprehensive exploration of the fusion of Artificial Intelligence (AI) and data science within the realm of sleep disorders, presenting innovative approaches to diagnosis, treatment, and personalized care. The interdisciplinary nature of this handbook fosters collaboration between experts from diverse fields, including computer science, engineering, neuroscience, medicine, public health, AI, data science, and sleep medicine. Each chapter delves into specific aspects of sleep disorder analysis, innovative methodologies, novel insights, and real-world applications that showcase the transformative potential of AI and data science in sleep medicine, from analyzing sleep patterns and predicting disorder risk factors to utilizing big data analytics for large-scale epidemiological studies. This handbook hopes to offer a comprehensive resource for researchers, clinicians, and policymakers striving to address the challenges in sleep medicine.

Handbook of Active Ageing and Quality of Life: From Concepts to Applications (International Handbooks of Quality-of-Life)

by Fermina Rojo-Pérez Gloria Fernández-Mayoralas

This handbook presents an overview of studies on the relationship of active ageing and quality of life. It addresses the new challenges of ageing from the paradigm of positive ageing (active, healthy and successful) for a better quality of life. It provides theoretical perspectives and empirical studies, including scientific knowledge as well as practical experiences about the good ageing and the quality of later life around the world, in order to respond to the challenges of an aged population. The handbook is structured in 4 sections covering theoretical and conceptual perspectives, social policy issues and research agenda, methods, measurement instrument-scales and evaluations, and lastly application studies including domains and geographical contexts. Chapter 5 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Handbook of Acute Pain Management

by Howard S. Smith Jennifer A. Elliott

Pain is a pervasive symptom present in multiple areas of medicine. It is imperative that physicians not only evaluate and diagnose the source of pain, but that they also recognize how to manage the actual pain symptoms with effective treatment. Handbook of Acute Pain Management is an essential reference for professionals to enhance their knowledge

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