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Handbook of ELISPOT: Methods and Protocols (Methods in Molecular Biology #2768)
by Alexander E. KalyuzhnyThis fourth edition volume expands on the previous editions with discussions on the latest protocols that can be applied in different laboratory landscapes ranging from purely research to clinical diagnostic environments. This volume particularly focuses on ELISpot validation and evaluation of antibodies used in this assay. The chapters in this volume cover topics such as peptides in T-Cell assays and ELISpot applications for monitoring infectious diseases like tuberculosis and SARS-CoV2; FluoroSpot; the use of AI for studying ELISpot; and comparing ELISpot with flow cytometry, feline coronavirus (FCoV2), and memory b-cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Handbook of ELISPOT: Methods and Protocols, Fourth Edition is a valuable resource to aid in the advancement of science and technology, and inspire scientists and researchers to determine and pursue new discoveries in this developing field.Chapters 5, 7, 11, 13, and 15 are available open access under Creative Commons Attribution 4.0 International License via link.springer.com.
Handbook of Early Intervention for Autism Spectrum Disorders: Research, Policy, and Practice (Autism and Child Psychopathology Series)
by Johnny L. Matson Peter Sturmey Dennis R. DixonThe Second Edition of this handbook provides significantly updated and expanded content and coverage, including new chapters on the changing epidemiology of autism spectrum disorder (ASD), measurement and assessment of problem behaviors, value-based care for ASD, conceptual foundations of evidence-based practices, the use of technology, and functional behavior assessment in ASD treatment. This unique volume addresses basic questions in salient detail, from epidemiology and diagnosis to guiding treatment decisions. In addition, it examines treatment delivery systems and new technologies to support individuals with ASD. Key areas of coverage include: History of the evolving diagnostic criteria for ASD. Early screening and diagnostic measures and practices. Ethics and economics of early intervention. Detailed descriptions of evidence-based practices in treating the behavioral deficits and excesses associated withASD. Interdisciplinary collaboration to address co-occurring conditions and treat the whole patient. Caregiver collaboration to foster treatment integrity and consistency to improve outcomes. The Second Edition of the Handbook of Early Intervention for Autism Spectrum Disorders is a must-have comprehensive reference for researchers, professors, and graduate students as well as clinicians and other scientist-practitioners in clinical child, developmental, and school psychology, child and adolescent psychiatry, social work, public health, pediatric medicine, rehabilitation, and special education.
Handbook of Early Pregnancy Care
by George Condous Tom BourneProblems in early pregnancy are among the most common conditions in gynecology and - with management becoming less invasive and depending more on accurate ultrasound and a good understanding of serum biochemistry - many countries now recommend that all maternity units have an early pregnancy section dedicated to managing these conditions. In additi
Handbook of Eating Disorders and Obesity
by Stephan Herpertz Stephan Zipfel Martina De ZwaanThis book covers the entire spectrum of eating disorders, including obesity, in a psychotherapy procedure-independent manner and is based on the latest treatment guidelines. All disorders are presented on the basis of current evidence and treatment guidelines that combine psychotherapeutic and pharmacological interventions to provide therapists with clear recommendations for treatment. The 3rd edition has been completely revised to include important current topics and chapters, such as the inclusion of eating disorders in ICD 11/DSM 5, the role of the microbiome and the role of modern media e.g. ehealth in prevention and treatment. In addition, the editors and authors address, among other topics, systemic therapy as a new evidence-based psychotherapy and the discussion of addiction mechanisms in eating and weight disorders, and provide an outlook on the role of neurostimulation procedures to address current developments in obesity and eating disorders. The book is suitable as a reference for physicians in training, educators, and psychologists, especially colleagues from the field of psychosomatics, psychiatrists, and psychotherapists in research, clinic and practice.
Handbook of Eicosanoids: Volume I, Part A (CRC Press Revivals)
by A. L. WillisBuilding upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text.
Handbook of Eicosanoids: Volume I, Part B (CRC Press Revivals)
by A. L. WillisBuilding upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text.
Handbook of Electroporation
by Damijan MiklavčičThis major reference work is a one-shot knowledge base on electroporation and the use of pulsed electric fields of high intensity and their use in biology, medicine, biotechnology, and food and environmental technologies. The Handbook offers a widespread and well-structured compilation of 156 chapters ranging from the foundations to applications in industry and hospital. It is edited and written by most prominent researchers in the field. With regular updates and growing in its volume it is suitable for academic readers and researchers regardless of their disciplinary expertise, and will also be accessible to students and serious general readers. The Handbook's 276 authors have established scholarly credentials and come from a wide range of disciplines. This is crucially important in a highly interdisciplinary field of electroporation and the use of pulsed electric fields of high intensity and its applications in different fields from medicine, biology, food processing, agriculture, process engineering, energy and environment. An Editorial Board of distinguished scholars from across the world has selected and reviewed the various chapters to ensure the highest quality of this Handbook.The book was edited by an international team of Section Editors: P. Thomas Vernier, Boris Rubinsky, Juergen Kolb, Damijan Miklavcic, Marie-Pierre Rols, Javier Raso, Richard Heller, Gregor Serša, Dietrich Knorr, and Eugene Vorobiev.
Handbook of Emergency Neurology: Handbook For Emergency Physicians
by Thomas P. Campbell Kevin M. KellyPatients with neurologic symptoms are frequently seen in the emergency department and require rapid and thorough evaluation. Appropriate assessment with tailored history-taking, localization of the neurological problem, differential diagnosis, focused testing, and urgent treatment when indicated are essential to prevent patient morbidity. Neurological examination and testing of patients are covered in-depth, along with common neurological presentations using a symptom-based approach, such as coma, dizziness and gait disturbance. Specific neurological disorders are also explored, including traumatic brain injury, ischemic stroke and transient ischemic attack and neurotoxicology. Chapters follow a basic outline, including an introduction and a pearls and pitfalls section, providing a succinct overview and key takeaway points for the busy clinician. This well organized handbook will serve as a concise, valued reference for the clinician to use in assisting the evaluation of the most common neurology related emergency department visits.
Handbook of Emergency Ophthalmology
by Brit Long Alex KoyfmanThis book provides emergency physicians with an easy-to-use guide for diagnosing and treating ophthalmologic conditions in the emergency department. Ophthalmologic complaints are very common, but many emergency physicians are not as confident as they would like to be when evaluating and managing these conditions. This book answers that need by giving step-by-step instructions on how to diagnose and treat common eye conditions, including glaucoma, infections, neuro-ophthalmologic conditions, and trauma. For each disorder, the book discusses presentation/symptoms, physical examination techniques, lab and imaging findings, differential diagnoses, treatment guidelines, and referral suggestions. The text is filled with images that clearly present these common ophthalmologic complaints and conditions and guide the emergency physician to an accurate and swift diagnosis. Handbook of Emergency Ophthalmology is an essential resource for emergency physicians, residents, medical students, nurses, and other healthcare workers who evaluate and manage patients with ophthalmologic conditions.
Handbook of Emotion Regulation
by Ross A. Thompson James J. GrossThis authoritative volume provides a comprehensive road map of the important and rapidly growing field of emotion regulation. Each of the 30 chapters in this handbook reviews the current state of knowledge on the topic at hand, describes salient research methods, and identifies promising directions for future investigation. The contributors who are the foremost experts in the field address vital questions about the neurobiological and cognitive bases of emotion regulation, how we develop and use regulatory strategies across the lifespan, individual differences in emotion regulation, social psychological approaches, and implications for psychopathology, clinical interventions, and health.
Handbook of Emotion Regulation, Second Edition
by James J. GrossReviewing the state of the science in a dynamic, thriving field, this influential handbook integrates knowledge from multiple psychological subdisciplines. Foremost experts address the neurobiological and cognitive bases of emotion regulation and examine how individuals develop and use regulatory strategies across the lifespan. The social context of emotion regulation is explored, as are personality processes and individual differences. Critical implications are discussed for psychopathology, psychosocial interventions, and health. Including helpful cross-referencing among chapters, the volume describes cutting-edge methods and identifies promising directions for future investigation. New to This Edition *Incorporates significant scientific advances and many new topics. *Greatly expanded coverage of clinical issues and applications. *Chapters on neural systems, delay of gratification, decision making, and health. *Chapters on adolescence, social baseline theory, and desire regulation, plus more.
Handbook of Emotion Regulation, Second Edition
by James J. GrossReviewing the state of the science in a dynamic, thriving field, this influential handbook integrates knowledge from multiple psychological subdisciplines. Foremost experts address the neurobiological and cognitive bases of emotion regulation and examine how individuals develop and use regulatory strategies across the lifespan. The social context of emotion regulation is explored, as are personality processes and individual differences. Critical implications are discussed for psychopathology, psychosocial interventions, and health. Including helpful cross-referencing among chapters, the volume describes cutting-edge methods and identifies promising directions for future investigation. As a special bonus, purchasers of the second edition can download a supplemental e-book featuring several notable, highly cited chapters from the first edition. New to This Edition *Incorporates significant scientific advances and many new topics. *Greatly expanded coverage of clinical issues and applications. *Chapters on neural systems, delay of gratification, decision making, and health. *Chapters on adolescence, social baseline theory, and desire regulation, plus more.
Handbook of Emotional Development
by Koraly Pérez-Edgar Vanessa LoBue Kristin A. BussThis handbook offers a comprehensive review of the research on emotional development. It examines research on individual emotions, including happiness, anger, sadness, fear, and disgust, as well as self-conscious and pro-social emotions. Chapters describe theoretical and biological foundations and address the roles of cognition and context on emotional development. In addition, chapters discuss issues concerning atypical emotional development, such as anxiety, depression, developmental disorders, maltreatment, and deprivation. The handbook concludes with important directions for the future research of emotional development. Topics featured in this handbook include:The physiology and neuroscience of emotions.Perception and expression of emotional faces.Prosocial and moral emotions.The interplay of emotion and cognition.The effects of maltreatment on children’s emotional development.Potential emotional problems that result from early deprivation. The Handbook of Emotional Development is an essential resource for researchers, clinicians/professionals, and graduate students in child and school psychology, social work, public health, child and adolescent psychiatry, pediatrics, and related disciplines.
Handbook of Emotional Disorders in Later Life: Assessment and Treatment
by Bob Knight Ken LaidlawAlthough the perceptions and realities of ageing have changed markedly over the last few decades, for practitioners working with older people, emotional problems remain a major factor of health and happiness in later life. This handbook provides a concise, authoritative and up to date guide to best practice in therapy for older people, for a wide range of mental health professionals. The editors bring together chapters by experienced trainers and clinicians that cover all the significant problems and issues in the assessment and treatment of emotional disorders in later life. The introductory chapters examine the individual, social, cultural and physical experience of ageing, and provide an essential background for a caring and professional understanding of related emotional disorders and their effective treatment. Throughout the book, key research and clinical experience is reported as underlying evidence based treatment, but the emphasis is on practical guidance for assessment and interventions, rather than detailed discussion of methodological issues. With each chapter written by a specialist in their field, a range of expertise is provided in a single source, making this book an invaluable resource for anyone dealing with the mental health needs of older people.
Handbook of Emotions, Fourth Edition
by Michael Lewis Lisa Feldman Barrett Jeannette M. Haviland-JonesRecognized as the definitive reference, this handbook brings together leading experts from multiple psychological subdisciplines to examine one of today's most dynamic areas of research. Coverage encompasses the biological and neuroscientific underpinnings of emotions, as well as developmental, social and personality, cognitive, and clinical perspectives. The volume probes how people understand, experience, express, and perceive affective phenomena and explores connections to behavior and health across the lifespan. Concluding chapters present cutting-edge work on a range of specific emotions. Illustrations include 10 color plates. New to This Edition *Chapters on the mechanisms, processes, and influences that contribute to emotions (such as genetics, the brain, neuroendocrine processes, language, the senses of taste and smell). *Chapters on emotion in adolescence, older age, and in neurodegenerative dementias. *Chapters on facial expressions and emotional body language. *Chapters on stress, health, gratitude, love, and empathy. *Many new authors and topics; extensively revised with the latest theoretical and methodological innovations.
Handbook of Emotions, Third Edition
by Michael Lewis Jeannette Haviland-JonesWidely regarded as the standard reference in the field, this handbook comprehensively examines all aspects of emotion and its role in human behavior. The editors and contributors are foremost authorities who describe major theories, findings, methods, and applications. The volume addresses the interface of emotional processes with biology, child development, social behavior, personality, cognition, and physical and mental health. Also presented are state-of-the-science perspectives on fear, anger, shame, disgust, positive emotions, sadness, and other distinct emotions. Illustrations include seven color plates.
Handbook of Encapsulation and Controlled Release (Encapsulation and Controlled Release)
by Munmaya MishraThe field of encapsulation, especially microencapsulation, is a rapidly growing area of research and product development. The Handbook of Encapsulation and Controlled Release covers the entire field, presenting the fundamental processes involved and exploring how to use those processes for different applications in industry. Written at a level comp
Handbook of Endobronchial Ultrasound: Diagnosis and Interventions
by Madhusmita Mohanty Mohapatra Pratap UpadhyaThis easy-to-use pocket book covers all aspects of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), a preferred diagnostic procedure for many pulmonary and mediastinal conditions. Chapters include topics ranging from anatomy and lymph node stations to detailed insights on endobronchial ultrasound instrumentation. The book discusses the indications and contraindications of EBUS, patient preparation, the technical aspect of scope insertion into airways, manipulation and sampling, and complications. Additionally, it provides the latest EBUS-related guidelines and serves as a handy clinical reference for practitioners. The book is relevant for postgraduate students of general and pulmonary medicine, thoracic surgeons, radiologists, nurses, EBUS technicians, and practitioners alike performing EBUS-TBNA.
Handbook of Endocrinology, Second Edition, Volume I
by George H. Gass Harold M. KaplanStay on top of the rapid changes sweeping endocrinology today with the latest information on important selected topics in The Handbook of Endocrinology. This extensive two-volume text provides an impressive breadth and depth of coverage difficult to find in other sources. After a broad survey of the functions of major endocrine glands, the book launches into detailed reviews of both established and hot, new research areas. Selected topics include:
Handbook of Endovascular Interventions
by Amit Kumar Kenneth OurielHandbook of Endovascular Interventions presents a step-wise approach to the techniques of peripheral vascular interventions. Covering interventions in all major organ systems, this concise and comprehensive resource provides the rationale on why these approaches have been adopted by most practicing vascular interventionalists. This volume also presents key information on intervention techniques and pitfalls, complications and their management, surgical management options, as well as landmark papers on the topic. Unique to this book is the inclusion of sections building an endovascular suite, and coding as well as international training paradigms across the globe. Authored by international experts from around the globe, Handbook of Endovascular Interventions is a true how-to book for the busy interventionalist.
Handbook of Endovascular Peripheral Interventions
by Yerem Yeghiazarians Christopher D OwensThe Handbook of Endovascular Peripheral Interventions has been written to serve as a comprehensive guide for both the beginner and advanced interventionalist. Covering all aspects of percutaneous peripheral vascular interventions, each chapter of this highly illustrated book provides a brief background, etiology, clinical presentation, imaging, and percutaneous treatment of different vascular conditions. Importantly, Tips of the Trade and How I Do It sections within each chapter make the handbook practical for daily use. These invaluable pearls are provided by contributing chapter authors who are experts in the field. Edited by Dr. Christopher D. Owens (Division of Vascular Surgery) and Dr. Yerem Yeghiazarians (Division of Interventional Cardiology), from the University of California San Francisco School of Medicine, the Handbook of Endovascular Peripheral Interventions is a collaborative effort between cardiologists, vascular surgeons, and radiologists. Since each subspecialty brings unique expertise and experience to the field, this handbook will be a valuable resource for all physicians currently working in peripheral vascular interventions.
Handbook of Epidemiology
by Iris Pigeot Wolfgang AhrensThis 5-volume reference covers the entire field of epidemiology, from statistical methods and study design, to specialized areas such as molecular epidemiology, and applications in clinical medicine and health services research. This updated edition of the Handbook of Epidemiology adds20 new chapters on: History of Epidemiological Methods and Concepts, Cluster Randomized Trials, Internet-Based Epidemiology, Misclassification, Sensitivity Analysis and Bias Analysis, Emergency and Disaster Health Surveillance, Statistical Inference, Data Management in Epidemiology, Bayesian Methods in Epidemiology, Generalized Estimating Equations, Directed Acyclic Graphs, Life Course Epidemiology, Physical Activity Epidemiology, Radiation Epidemiology, Epidemiology of Obesity, Epidemiology of Respiratory Allergies and Asthma, Epidemiology of Dental Diseases, Epidemiology of Digestive Diseases, Epidemiology of Psychiatric Disorders, Epidemiology of Diabetes. All other chapters are extensively revised from the 1st edition. This is a reference for epidemiological researchers and graduate students in public health. "
Handbook of Epilepsy Treatment
by Simon ShorvonMake your way through the epilepsy maze Epilepsy is a complex neurological condition. There are many modern treatment options, and treatment should nowadays be tailored to an individual patient. But identification of the best therapy can be a labyrinthine process. The Handbook of Epilepsy Treatment provides a practical pathfinder for treating epilepsy based on published evidence and the author’s 30 years of specialist clinical experience. Direct in style but comprehensive in content, with ample tables and summaries, the Handbook of Epilepsy Treatment covers: Treatment of the different forms and causes of epilepsy Treatment in the different commonly encountered clinical situations Treatment in children, in adults, in the elderly, in women, in epilepsy syndromes and in those with special needs and requirements Epilepsy drugs – their pharmacology, kinetics, side effects, effectiveness and practical usage in the clinic Epilepsy surgery – the various types, the indications, assessment and outcome A succinct pharmacopeia summarizes the entire range of anti-epileptic medications with emphasis on effective prescribing in the clinical setting. The Handbook of Epilepsy Treatment will help you and your patient find the best path to control epilepsy for each individual’s situation.
Handbook of Equine Parasite Control
by Martin K. Nielsen Craig R. ReinemeyerHandbook of Equine Parasite Control, Second Edition offers a thorough revision to this practical manual of parasitology in the horse. Incorporating new information and diagnostic knowledge throughout, it adds five new sections, new information on computer simulation methods, and new maps to show the spread of anthelmintic resistance. The book also features 30 new high-quality figures and expanded information on parasite occurrence and epidemiology, new diagnostics, treatment strategies, clinical significance of infections, anthelmintic resistance, and environmental persistence. This second edition of Handbook of Equine Parasite Control brings together all the details needed to appropriately manage parasites in equine patients and support discussions between horse owners and their veterinarians. It offers comprehensive coverage of internal parasites and factors affecting their transmission; principles of equine parasite control; and diagnosis and assessment of parasitologic information. Additionally, the book provides numerous new case histories, covering egg count results from yearlings, peritonitis and parasites, confinement and deworming, quarantine advice, abdominal distress in a foal, and more. A clear and concise user-friendly guide to equine parasite control for veterinary practitioners and students Fully updated with new knowledge and diagnostic methods throughout Features brand new case studies Presents 30 new high-quality figures, including new life-cycle charts Provides maps to show the spread of anthelmintic resistance Handbook of Equine Parasite Control is an essential guide for equine practitioners, veterinary students, and veterinary technicians dealing with parasites in the horse.
Handbook of Equine Parasite Control
by Craig Reinemeyer Martin NielsenA must-have guide for any equine veterinarian, this is a practical and concise handbook on the control of equine parasites. It enables you to advise your clients effectively on evidence-based parasite control programs. The first section of the book reviews the basic biology of internal parasites and the factors influencing their transmission. The second section discusses the general principles of parasite control. The third section provides diagnostic and assessment tools for interpreting clinical, historical and laboratory information. Finally the fourth section contains 20 case studies reflecting the full range of parasites and providing detailed answers and discussions, providing you with the opportunity to practice the application of knowledge and illustrating the concepts of modern parasite control.Handbook of Equine Parasite Control is an invaluable companion for equine veterinary practitioners, veterinary students, equine veterinary technicians and nurses, researchers in equine parasitology, horse owners, and farm and stable managers.