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Handbook of Adaptive Designs in Pharmaceutical and Clinical Development
by Shein-Chung Chow Annpey PongIn response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development. Handbook of Adaptive Designs in Pharmaceutical and Clinical Development provides a comprehensive and unified presentation of the princip
Handbook of Addiction, Recovery and Quality of Life: Cross-cutting Perspectives from Around the Globe (International Handbooks of Quality-of-Life)
by Maria Florence Wouter Vanderplasschen Mansoo Yu Jessica De Maeyer Shazly SavahlThis handbook brings together research and innovation across two important and related fields, quality of life (QoL) and addiction recovery. Though both fields of research are equally vibrant, this volume brings together the advancing scholarly exploration of the intersection between QoL and addiction recovery. It provides comprehensive coverage of the theoretical perspectives on QoL in the field of addiction and recovery; instruments and methodologies to assess QoL; different types of addiction in specific populations and QoL; and practices and interventions for supporting recovery and promoting QoL. It importantly includes international and intercultural perspectives on QoL and addiction recovery. By including sound theoretical, conceptual, historical, empirical and cross-cultural contributions on QoL and addictions, the volume offers many opportunities for advancing support, treatment and recovery of persons with addiction problems based on their subjective perspectives and experiences. This handbook is a go-to resource for a wide interdisciplinary readership interested in quality-of-life research, subjective well-being, public health, and addiction research.
Handbook of Adhesive Technology
by Antonio Pizzi Kashmiri L. MittalThis classic reference examines the mechanisms driving adhesion, categories of adhesives, techniques for bond formation and evaluation, and major industrial applications. Integrating recent innovation and improved instrumentation, the work offers broad and comprehensive coverage. This edition incorporates several new adhesive classes, new application topics, and recent developments with nanoadhesives and bio-based adhesives. Existing chapters are thoroughly updated, revised, or replaced and authored by top specialists in the field. Abundant figures, tables, and equations appear throughout the work.
Handbook of Adolescent Behavioral Problems
by Thomas P. Gullotta Robert W. Plant Melanie A. EvansThe Second Edition of the Handbook of Adolescent Behavioral Problems clarifies the current state of treatment and prevention through comprehensive examinations of mental disorders and dysfunctional behaviors as well as the varied forces affecting their development. New or revised chapters offer a basic framework for approaching mental health concerns in youth and provide the latest information on how conditions (e. g. , bipolar disorder, suicidality, and OCD) and behaviors (e. g. , sex offenses, gang activities, dating violence, and self-harm) manifest in adolescents. Each chapter offers diagnostic guidance, up-to-date findings on prevalence, biological/genetic aspects, risk and resilience factors, and a practical review of prevention and treatment methods. Best-practice recommendations clearly differentiate among what works, what might work, what doesn't work, and what needs further research across modalities, including pharmacotherapy. Key topics addressed include: Families and adolescent development. Adolescent mental health and the DSM-5. Oppositional Defiant Disorder and Conduct Disorder. Autism spectrum disorder. Media and technology addiction. School failure versus school success. Bullying and cyberbullying. The Second Edition of the Handbook of Adolescent Behavior Problems is a must-have reference for researchers, clinicians, allied practitioners and professionals, and graduate students in school and clinical child psychology, education, pediatrics, psychiatry, social work, school counseling, and public health.
Handbook of Adolescent Health Psychology
by William T. O'Donohue Lauren Woodward Tolle Lorraine T. BenutoAdolescence is a pivotal period of development with respect to health and illness. It is during adolescence that many positive health behaviors are consolidated and important health risk behaviors are first evident; thus, adolescence is a logical time period for primary prevention. In addition, the predominant causes of morbidity and mortality in adolescence are quite different from those of adults, indicating that early identification and treatment of adolescent health problems must be directed to a unique set of targets in this age group. Moreover, because of the particular developmental issues that characterize adolescence, intervention efforts designed for adults are often inappropriate or ineffective in an adolescent population. Even when chronic illnesses are congenital or begin in childhood, the manner in which the transition from childhood to adolescence to young adulthood is negotiated has important implications for disease outcomes throughout the remainder of the person's life span. Organized in five major sections (General Issues, Developmental Issues, Treatment and Training, Mental Health, and Physical Health) and 44 chapters, Handbook of Adolescent Health Psychology addresses the common and not so common health issues that tend to affect adolescents. Coverage includes: Context and perspectives in adolescent health psychology Health literacy, health maintenance, and disease prevention in adolescence Physical disorders such as asthma, obesity, physical injury, and chronic pain Psychological disorders such as substance abuse, attention deficit hyperactivity disorder, depression, and eating disorders Congenital chronic diseases such as type 1 diabetes and spina bifida Handbook of Adolescent Health Psychology is the definitive reference for pediatricians, family physicians, health psychologists, clinical social workers, rehabilitation specialists, and all practitioners and researchers working with adolescents.
Handbook of Adult Resilience
by John Reich Alex ZautraThe first book to move beyond childhood and adolescence to explore processes of resilience across the lifespan, this cutting-edge volume synthesizes the best current research in the field. Contributors offer a comprehensive examination of resilience at multiple levels of analysis, from genetic and physiological factors through individual, family, and community processes. Compelling topics include Whether resilience is best understood as a trait, a dynamic developmental process, an outcome, or all of the above. How resilience intersects with health and well-being across the adult life cycle. Cross-cultural issues in conceptualization and measurement. Ways to enhance adult resilience, including reviews of exemplary programs.
Handbook of Adverse Childhood Experiences: A Framework for Collaborative Health Promotion (Issues in Clinical Child Psychology)
by Michael C. Roberts Sharon G. Portwood Michael J. LawlerThis handbook explores ways to unify the study and application of adverse childhood experiences (ACEs) across multiple fields and disciplines, including clinical child and adolescent psychology, school psychology, pediatrics, social work, public health, education, and other health and human services. The book outlines a cohesive framework that organizes critical ACEs concepts throughout individual chapters, highlighting key issues and themes across settings and disciplines as well as gaps in current knowledge. Chapters examine interdisciplinary and collaborative approaches to ACEs and their impact on health and well-being within a specific topic area or setting. In addition, chapters review the foundations and development of the relevant science and provide examples of ACEs research and intervention applications as well as suggestions for continued advancement in this field. Key areas of coverage include: Definition and measurement of ACEs. Theory and models guiding ACEs research and practice. Applications of ACEs science across settings, including healthcare, mental and behavioral health, schools, justice system, and child welfare system. Applications of ACEs to public health and policy issues. Prevention strategies and policy approaches to ACEs. Handbook of Adverse Childhood Experiences is an essential resource for researchers, professors, and graduate students as well as clinicians and related mental health and medical therapists and professionals in developmental and clinical child and adolescent psychology, school psychology, child and adolescent psychiatry, social work, child and family studies, public health, pediatrics, and all interrelated disciplines.
Handbook of African American Health
by Sandra Taylor Wornie Reed Anthony J. LemelleThe U.S. Census Bureau reports particular demographic, social, and health conditions for African Americans. Population-wide, the African American community has a higher mortality rate from cancer and diabetes than the rest of the population, a higher infant mortality rate, and a lower vaccination rate for influenza and pneumonia. The contributions to this comprehensive Handbook of African American Health uncover the specific demographic conditions of the African American population, and outline social interventions for both physical and mental health at the primary, secondary, and tertiary levels. The 26 contributions to this comprehensive volume cover interventions for a diverse range of health problems, including: -obesity and cardiovascular disease -diabetes -asthma and other respiratory diseases -smoking, alcohol, and recreational drug abuse -risky sexual behaviors -cancer screening, prevention, and survivorship -infant mortality -community and interpersonal violence -mental health From a healthcare standpoint, it also examines specific interventions for treatment compliance, health care access, and community collaborations. This volume will be an invaluable resource for researchers in medical sociology, mental health studies, public health, health behavior, and African American studies.
Handbook of African American Health
by Thomas Gullotta Robert HamptonWith a focus on how to improve the effectiveness and cultural competence of clinical services and research, this authoritative volume synthesizes current knowledge on both the physical and psychological health of African Americans today. In chapters that follow a consistent format for easy reference, leading scholars from a broad range of disciplines review risk and protective factors for specific health conditions and identify what works, what doesn't work, and what might work (i.e., practices requiring further research) in clinical practice with African Americans. Historical, sociocultural, and economic factors that affect the quality and utilization of health care services in African American communities are examined in depth. Evidence-based ways to draw on individual, family, and community strengths in prevention and treatment are highlighted throughout.
Handbook of Agricultural Productivity: Volume II: Animal Productivity (Crc Series In Nutrition And Food)
by Miloslav RechciglThe greatest challenge of our time is to produce sufficient food ot keep pace with the rapidly growing population. In the opinion of experts, during the next 25 years there will be a need for as much food as was produced in the entire history of mankind to date. Of the various measures available, improvement in agricultural productivity is judged as the ultimate means of augmenting food production and supplies. In this Handbook, an international team of experts consider the most important factors affecting production of both crops and livestock. This Handbook is intended as a scientific guide to practitioners and students, as well as to researchers, who should find here stimulating ideas for further exploration.
Handbook of Air Quality and Climate Change
by Hajime Akimoto Hiroshi TanimotoThis handbook covers the air quality/air pollution from the viewpoints of causing impacts on human/ecosystem health and climate change. Traditionally, air pollution has been a concern mainly in terms of its impacts on human health, and it is still an immediate public and governmental concern in most Asian countries. However, in recent years so-called extreme weather events, such as stronger tropical cyclones, flooding, drought, and other phenomena, have been manifested causing tremendous losses of human lives and properties. Importantly, climate models tell us that such extreme weather events are actually induced by anthropogenic global warming. It has been pointed out that mitigation or alleviation of such climate change leading to the extreme weather events in the next 30 years can be possible only by reducing air pollutants with positive radiative forcing such as ozone or methane, which are called short-lived climate pollutants (SLCPs). Here, concerns about mitigation of air pollutants from the points of human health and climate change have merged. This book covers different kinds of air pollutants and radiative forcers and how they can be measured. It also mentions the situation of air pollutants in different continents and their regional impacts to human health, environment and economy as well as their link to extreme weather events. The book presents how the air pollution and climate change can be mitigated and how clean air technologies and international initiatives for co-controlling air pollution and climate change have been developed.
Handbook of Alcoholism (Handbooks in Pharmacology and Toxicology)
by Gerald Zernig Alois Saria Martin Kurz Stephanie S. O’MalleyWhile the war on drugs continues to attract world attention, it is often overlooked that alcoholism remains a major worldwide health concern. No matter what your expertise, the CRC Handbook of Alcoholism can help you acquire the necessary skills to treat problem drinkers and alcohol-dependent patients.In three sections - Patient Care, Research,
Handbook of Alcoholism Treatment Approaches: Effective Alternatives, Third Edition
by William R. Miller Reid K. HesterThe Handbook of Alcoholism Treatment Approaches is a comprehensive, results-based guide to alcohol treatment methods. This handbook surveys the various models that have been used to define alcoholism, ending with a discussion of what the authors call "an informed eclecticism. " Using this approach, clinicians develop a spectrum of treatment approaches that have proved effective in practice, then match specific clients with the treatment methods that offer the greatest opportunities for success in these specific circumstances. This new edition of this handy reference provides both practitioners and researchers with a rich source of information on treatment interventions demonstrated to be the most successful. Clinical Psychologists and Alcohol Treatment Specialists.
Handbook of Algal Technologies and Phytochemicals: Volume I Food, Health and Nutraceutical Applications
by Gokare A. Ravishankar Ambati Ranga RaoKey features: The most comprehensive resource available on the biodiversity of algal species, their industrial production processes and their use for human consumption in food, health and varied applications. Emphasis on basic and applied research, addressing aspects of scale-up for commercial exploitation for the development of novel phytochemicals (phytochemicals from algae). Addresses the underexplored and underutilized potential of chemicals from marine sources for health benefits. Each chapter, written by expert contributors from around the world, includes Summary Points, Figures and Tables, as well as up-to-date references. The first book in this two-volume set explores the diversity of algal constituents for health and disease applications. The commercial value of chemicals of value to food and health is about $6 billion annually, of which 30 percent relates to micro and macro algal metabolites and products for health food applications. This comprenhensive volume looks in detail at algal genomics and metabolomics as well as mass production of microalgae. As a whole, the two-volume set covers all micro and macro algal forms and their traditional uses; their constituents which are of value for food, feed, specialty chemicals, bioactive compounds for novel applications, and bioenergy molecules. Bio-business and the market share of algae-based products are also dealt with, providing global perspectives.
Handbook of Algal Technologies and Phytochemicals: Volume II Phycoremediation, Biofuels and Global Biomass Production
by Gokare A. Ravishankar Ambati Ranga RaoKey Features The most comprehensive resource available on the biodiversity of algal species, their industrial production processes and their use for human consumption in food, health and varied applications. Emphasis on basic and applied research, addressing aspects of scale-up for commercial exploitation for the development of novel phytochemicals (phytochemicals from algae). Addresses the underexplored and underutilized potential of chemicals from marine sources for health benefits. Each chapter, written by expert contributors from around the world, includes a Dictionary of Terms, Key Facts, Summary Points, Figures and Tables, as well as up-to-date references. The second book in this two-volume set explores phycoremedation applications, and the sustainable use of algae for biofuels and other products of economic value. It also looks at aspects such as macro- and micro algal impact on marine ecosystem and remote sensing of algal blooms. The commercial value of chemicals of value to food and health is about $6 billion annually, of which 30 percent relates to micro and macro algal metabolites and products for health food applications. As a whole, the two volumes explore the aspects of diversity of micro and macro algal forms, their traditional uses; their constituents which are of value for food, feed, specialty chemicals, bioactive compounds for novel applications, and bioenergy molecules. Bio-business and the market share of algae-based products are also dealt with, providing global perspectives.
Handbook of Analysis of Oligonucleotides and Related Products
by Jose V. Bonilla G. Susan SrivatsaOligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essen
Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (CRC Press Revivals)
by Steven H.Y. Wong Irving SunshineAdapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.
Handbook of Analytical Validation
by Michael E. Swartz Ira S. KrullWritten for practitioners in both the drug and biotechnology industries, the Handbook of Analytical Validation carefully compiles current regulatory requirements on the validation of new or modified analytical methods. Shedding light on method validation from a practical standpoint, the handbook:Contains practical, up-to-date guidelines for analyti
Handbook of Anatomical Models for Radiation Dosimetry (Series in Medical Physics and Biomedical Engineering)
by Keith F. Eckerman Xie George XuOver the past few decades, the radiological science community has developed and applied numerous models of the human body for radiation protection, diagnostic imaging, and nuclear medicine therapy. The Handbook of Anatomical Models for Radiation Dosimetry provides a comprehensive review of the development and application of these computational mode
Handbook of Angioplasty and Stenting Procedures
by Robert A. Morgan Eric WalserThe Techniques in Interventional Radiology series of handbooks describes in detail the various interventional radiology procedures and therapies that are in current practice. The series comprises four titles, which in turn cover procedures in angioplasty and stenting, transcatheter embolization and therapy, biopsy and drainage and ablation. Each book is laid out in bullet point format, so that the desired information can be located quickly and easily. Interventional radiologists at all stages, from trainees through to specialists, will find this book a valuable asset for their practice. The Handbook of Angioplasty and Stenting Procedures first discusses the basic tools and principles of these procedures, then moves onto describing each operation that can be performed using these techniques. Dr. Robert Morgan is Consultant Radiologist at St Georges' Hospital, London, UK, and Dr. Eric Walser is Professor of Radiology at the Mayo Clinic in Florida, USA.
Handbook of Animal Diversity
by Richard E. BlackwelderThis book is a summary of the diversity between and within the classes of animals. It is intended for reference on all aspects of animals that can be studied comparatively, but such comparisons requires that the occurrence of the feature in question beknown for more than just one or two groups. It is in large part a book on invertebrate animals because the vertebrates from only a small part of the diversity of animals.
Handbook of Animal Models and its Uses in Cancer Research
by Surajit Pathak Antara Banerjee Atil BisginThis reference book compiles together different animal models in cancer research. It provides knowledge and a better understanding of the advancement of the molecular and cellular mechanisms associated with the progression, formation, and clinical results of various types of cancer from the evidence collected from animal models utilized for cancer research. It discusses animal models for screening anti-cancer drugs and exploration of gene therapy. It presents different methods used to construct cancer animal models and the progress of each animal model in tumor research. The book also highlights the applications of genetic engineering, including CRISP/Cas9, in designing and developing animal models for cancer research. Further, it discusses strategies for modeling animals for investigating growth, metastasis, tumor-associated inflammation and microenvironment, cancer stem cells, tumor heterogeneity, and therapeutic resistance. This book is s a valuable resource for basic and translational cancer researchers, clinicians, and health care.
Handbook of Animal Models in Transplantation Research
by Donald V. Cramer Luis G. Podesta Leonard MakowkaHandbook of Animal Models in Transplantation Research is a new surgical handbook that provides detailed information concerning the transplantation of a variety of tissues in experimental animals. The text provides a practical guide for experienced investigators to develop new surgical transplantation models for application in a laboratory setting. Each chapter gives consistent descriptions of the anatomical considerations, the surgical model, and potential applications of the procedure. The organ systems covered include the heart and/or lung, liver, small bowel, kidneys, and bone marrow. The species selected for representation of each experimental model is based upon the usefulness and frequency of the model for studies in transplantation research. This book is important for all experimental surgeons, transplantation biologists, and students of surgical research.
Handbook of Animal Models of Renal Failure
by Stephen R. AshThis text presents a variety of methods of creation of renal failure, by the author‘s experience in the study and support of laboratory animal models of renal failure. This text also discusses three studies on the mechanisms of renal damage and renal failure in animal models.
Handbook of Anthropometry
by Victor R. PreedyAlthough its underlying concept is a relatively simple one--the measurement of the human body and its parts--anthropometry employs a myriad of methods and instruments, and is useful for a variety of purposes, from understanding the impact of disease on individuals to tracking changes in populations over time. The first interdisciplinary reference on the subject, the Handbook of Anthropometry brings this wide-ranging field together: basic theory and highly specialized topics in normal and abnormal anthropometry in terms of health, disease prevention, and intervention. Over 140 self-contained chapters cover up-to-date indices, the latest studies on computerized methods, shape-capturing systems, and bioelectrical impedance, data concerning single tissues and whole-body variables, and reports from different areas of the world. Chapters feature helpful charts and illustrations, cross-references to related chapters are included, and key points are presented in bullet form for ease of comprehension. Together, the Handbook's thirteen sections entail all major aspects of anthropometrical practice and research, including: Tools and techniques. Developmental stages, from fetus to elder. Genetic diseases, metabolic diseases, and cancer. Exercise and nutrition. Ethnic, cultural, and geographic populations. Special conditions and circumstances. The Handbook of Anthropometry is an invaluable addition to the reference libraries of a broad spectrum of health professionals, among them health scientists, physicians, physiologists, nutritionists, dieticians, nurses, public health researchers, epidemiologists, exercise physiologists, and physical therapists. It is also useful to college-level students and faculty in the health disciplines, as well as to policymakers and ergonomists.