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Handbook of Laboratory Animal Management and Welfare
by Sarah Wolfensohn Maggie LloydThis bestseller has been an essential book for all those working with laboratory animals since it was first published in 1994. This fourth edition retains all the classic features that have made it a must-have reference including emphasis on best practice in order to improve animal welfare. The contents have been thoroughly updated and reorganised to make sure it is a really practical book for day-to-day use in the laboratory. The first section of the book covers principles applicable to all species, for example husbandry, handling and the education and training required by scientists and technical staff working with animals in the laboratory. Later chapters focus on specific species or groups of species.New to this edition:* Reflects changes in European legislation and their impact on national legislation* Covers recommendations for the education and training of those carrying out animal experiments across Europe * New chapters on ethical considerations and balancing animal welfare with science* New information on environmental enrichment for laboratory animals* Covers advancements in anaesthesia and analgesia and techniques* Spiral bound for ease-of-use as a bench-top referenceThis book is ideal for all personnel carrying out scientific procedures using animals, particularly during training and also for the new researcher. It will also be essential reading for study directors designing research programmes, animal technicians and veterinarians working with laboratory animal species.
Handbook of Laboratory Animal Science: Essential Principles and Practices
by Jann HauBuilding upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide. It covers the essential principles and practices of Laboratory Animal Science as well as selected animal models in scientific disciplines where much progress has been made in recent years. Each individual chapter focuses on an important subdiscipline of laboratory animal science, and the chapters can be read and used as stand-alone texts, with only limited necessity to consult other chapters for information. With new contributors at the forefront of their fields, the book reflects the scientific and technological advances of the past decade. It also responds to advances in our understanding of animal behavior, emphasizing the importance of implementing the three Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort. This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university veterinarians, and for other specialists in laboratory animal science.
Handbook of Lasers in Dermatology
by Keyvan NouriThis book discusses lasers and light technologies in dermatology. The innovation is due to the book format: a handbook. It is the first handbook of lasers in dermatology, facilitating access to information to all individuals interested in lasers in this specific medical field . The most recent lasers devices and its applications will be discussed. Illustrations and tables will make the book didactic and comprehensive. Lasers in dermatology are a constantly evolving field. Over the past few decades, novel devices have been developed and new indications for their use have emerged. A broad understanding of the relationship between science and laser principles is the foundation of a solid dermatologic practice. The Lasers in Dermatology Handbook is a tool to understand the use of lasers in clinical practice. Important topics such as vascular lesions, warts, acne, scars, and pigmented lesions are presented and discussed in all aspects. The wide spectrum of laser and light technologies available for skin resurfacing and rejuvenation will be covered as well. Written by internationally renowned authors, this handbook serves as a cornerstone for laser applications and provides updated information for all physicians, particularly dermatologists, interested in implementing lasers in their practice.
Handbook of Life Course Health Development
by Richard M. Lerner Neal Halfon Christopher B. Forrest Elaine M. FaustmanThis book is open access under a CC BY 4. 0 license. This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors' research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women's cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.
Handbook of Life Course Occupational Health (Handbook Series in Occupational Health Sciences)
by Morten Wahrendorf Tarani Chandola Alexis DescathaThis handbook provides a comprehensive overview of recent developments in research on the relationship between occupational trajectories over the life course and health. It uncovers the impact of far-reaching changes of work and employment, as evidenced by increased flexibility, discontinuity, and technological innovation, and offers insights into recent theoretical and methodological developments addressing this challenge. In its main parts, it presents the best evidence to readers about the following topics: early life influences on (un)healthy work, chronic exposure to occupational risks; nonstandard employment and poor health; work continuation with chronic disease; occupational determinants of healthy aging. In its final part, it discusses policy implications of current knowledge and points to the need of developing new solutions in research and practice, not least in times of climate crisis and the new pandemic.The important handbook has been prepared by a distinguished editorial team, with chapters written by prominent international experts. Despite its continuous reference to scientific knowledge it addresses its content to a broader, non-specialized readership.
Handbook of Lipid Bilayers
by Derek MarshNow in its second edition, the Handbook of Lipid Bilayers is a groundbreaking work that remains the field's definitive text and only comprehensive source for primary physicochemical data relating to phospholipid bilayers. Along with basic thermodynamic data, coverage includes both dynamic and structural properties of phospholipid bilayers. It is an
Handbook of Lipid Membranes: Molecular, Functional, and Materials Aspects
by Cyrus R. Safinya Joachim O. RädlerThis handbook provides a unique overview of lipid membrane fundamentals and applications. The fascinating world of lipids that harbor and govern so many biological functionalities are discussed within the context of membrane structures, interactions, and shape evolution. Beyond the fundamentals in lipid science, this handbook focuses on how scientists are building bioinspired biomimetic systems for applications in medicine, cosmetics, and nanotechnology. Key Features: Includes experimental and theoretical overviews on the role of lipids, with or without associated biomolecules, as structural components imparting distinct membrane shapes and intermembrane interactions Covers the mechanisms of lipid-membrane curvature, by peptide and protein binding, and the roles of signalling lipids and the cytoskeleton in plasma membrane shape evolution Covers advanced X-ray and force measurement techniques Discusses applications in biomedicine, cosmetics, and nanotechnology, including lipid vectors in nucleic acid, drug delivery in dermal applications, and lipid-based sensors and artificial biointerfaces Covers artificial membranes from block copolymers, synthetic copolypeptides, and recombinant proteins Includes an exciting section that explores the role of lipids in the origin of life in hydrothermal conditions This book is a highly informative companion for professionals in biophysics, biochemistry, physical chemistry, and material and pharmaceutical sciences and bioengineering.
Handbook of Listeria Monocytogenes
by Dongyou LiuOnce feared as a deadly intracellular bacterium with the extraordinary capacity to survive a wide array of arduous external stressors, Listeria monocytogenes is increasingly recognized as a preferred vector for delivering anti-infective and anti-cancer vaccine molecules. A reliable, single-source reference on the fundamental aspects of
Handbook of Long Term Care of The Childhood Cancer Survivor
by Grace A. Mucci Lilibeth R. TornoThis authoritative reference examines in depth the myriad challenges facing pediatric cancer survivors and proposes a robust framework for structured follow-up of these patients through adulthood. Approaches to long-term follow-up include both established models of care and targeted models of lifelong surveillance of late effects by bodily systems and neurological outcomes. Sections devoted to quality of life and re-entry after treatment focus on key concerns such as health risk behaviors, school and career issues, psychological challenges, and care disparities. And a robust resources section adds extra usefulness to the expert coverage. Among the Handbook's topics: Developmental considerations in the transition from child and adolescent to adult survivorship. Long-term follow-up roadmaps by disease and treatment. Neuropsychological effects of pediatric brain tumors and associated treatment. Building resiliency in childhood cancer survivors: a clinician's perspective. School issues and educational strategies for survivors of childhood cancer. Educating and preparing the childhood cancer survivor for long-term care: a curriculum model for cancer centers. A work of rare scope, scholarship, and clinical acumen, the Handbook of Long-Term Care of the Childhood Cancer Survivor is a rewarding, practice-building resource essential to a wide range of healing professionals, including pri mary care physicians, pediatricians, oncologists, nurses, psychologists, neuropsychologists, child psychologists, and licensed therapists.
Handbook of Lower Extremity Reconstruction: Clinical Case-Based Review and Flap Atlas
by Dennis P. Orgill Scott T. Hollenbeck Peter B. ArnoldThis focused, concise book offers an in-depth analysis of lower extremity reconstruction alongside region-specific photos and illustrations. As an anatomical atlas, it seeks to aid the visual learner in showcasing the key steps in setting up and raising the flap for a given defect.Organized into two sections, opening chapters are arranged by general location, focusing specifically on the lower limb. Each general location of a wound is accompanied by an examination of relevant anatomy, including blood supply, nerve supply, arc of rotation of the tissue, and local flap options. Following a description of the anatomy, subsequent paragraphs explain the application of relevant local flap options. Section two incorporates flap demonstration and application into each chapter, offering a more detailed description, true and specific to each anatomical site of the technique.Supplemented by high-quality images and figures, Handbook of Lower Extremity Reconstruction: Clinical Case-Based Review and Flap Atlas is an invaluable reference for practicing plastic and orthopedic surgeons and residents in training.
Handbook of Lumbar Spine and Lower Extremity Examination: A Practical Guide
by Roger PillemerIn addition to complementary radiographic imaging, the physical exam is an essential diagnostic element for the orthopedic surgeon. As such, learning to perform this exam thoroughly is of utmost importance to medical students, residents and interns on an orthopedic rotation and in later practice.This practical text succinctly presents all of the necessary information regarding the physical examination of the lower extremity and lumbar spine. The lower spine, hip, knee, and foot and ankle are discussed in dedicated thematic sections, with each section comprised of three main chapters. The initial chapter describes the musculoskeletal anatomy and function of the joint, presenting the tests themselves along with the rationale for performing them. The second chapter presents the systematic examinations carried out in every case, and the third chapter describes examinations for specific conditions relating to the joint, including tendinopathies, osteoarthritis, neurological conditions, deformities and more. Plentiful bullet points and color images throughout the text describe and illustrate each test and physical sign.Convenient and user-friendly, Handbook of Lumbar Spine and Lower Extremity Examination is a valuable, portable guide to this all-important diagnostic tool for students and practitioners alike.
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences
by Yashwant PathakHandbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems
Handbook of MRI Technique
by Catherine WestbrookNow entering its fourth edition, the market-leading Handbook of MRI Technique has been fully revised and updated to incorporate new technologies and developments essential to good practice. Written specifically for technologists and highly illustrated, it guides the uninitiated through scanning techniques and helps more experienced technologists to improve image quality.The first part of the book considers the main aspects of theory that relate to scanning and also includes practical tips on gating, equipment use, patient care and safety, and information on contrast media. The second half provides step-by-step instruction for examining each anatomical area, beginning with a basic anatomy section followed by sections on indications, patient positioning, equipment, artefacts and tips on optimizing image quality.Written by an international team of technologists from the United States, United Kingdom and EuropeSuitable for users for all types of MRI systemsNow includes key points throughout for quick referenceCompanion website at www.wiley.com/go/westbrook/mritechnique with self-assessment and image flashcardsHandbook of MRI Technique continues to be the ideal support both for radiographers new to MRI and for regular users looking for information on alternative techniques and suggestions on protocol modifications.
Handbook of MRI Technique
by Catherine WestbrookThe progress of magnetic resonance imaging (MRI) as a clinical tool has been extraordinary, out-stripping the rate of development of any other imaging technique. There has been a huge increase in the practical applications of MRI techniques and its uses look likely to extend even further with the development of high speed gradients and pulse sequences. The Handbook of MRI Technique has proved highly successful in guiding the uninitiated through scanning techniques and helping more experienced technologists to improve image quality. The third edition of this highly successful book has been fully revised and updated to consider new technologies and developments essential to good practice. The book is split into two parts. Part 1 considers the main aspects of theory that relate to scanning and also includes practical tips on gating, equipment use, patient care and safety, and information on contrast media. Part 2 provides step by step instruction for examining each anatomical area, beginning with a basic anatomy section, followed by sections on indications, patient positioning, equipment, artefacts and tips on optimizing image quality. A section of problem-solving exercises completes the book. Now in full color throughout with over 200 illustrations this book will continue to appeal to radiographers new to MRI and regular users who are looking for information on alternative techniques and suggestions on protocol modifications. Completely revised and updated Over 100 brand new photographs and line drawings Written by technologists for technologists With contributions from MRI technologists in the USA and Australia Suitable for users of all types of MRI systems
Handbook of MRI Technique
by Catherine WestbrookHANDBOOK OF MRI TECHNIQUE FIFTH EDITION Distinguished educator Catherine Westbrook delivers a comprehensive and intuitive resource for radiologic technologists in this newly revised Fifth Edition of the Handbook of MRI Technique. With a heavy emphasis on protocol optimisation and patient care, the book guides the uninitiated through scanning techniques and assists more experienced technologists with image quality improvement. The new edition includes up-to-date scanning techniques and an additional chapter on paediatric imaging. The latest regulations on MRI safety are referenced and there are expanded sections on slice prescription criteria. The book also includes the contributions of several clinical experts, walking readers through key theoretical concepts, discussing practical tips on cardiac gating, equipment use, patient care, MRI safety, and contrast media. Step-by-step instruction is provided on scanning each anatomical area, complete with patient positioning and image quality optimisation techniques. The book includes: A thorough introduction to the concepts of parameters and trade-offs, as well as pulse sequences, flow phenomena, and artefacts Comprehensive explorations of cardiac gating and respiratory compensation techniques, patient care and safety, contrast agents, and slice prescription criteria Practical discussions of a wide variety of examination areas, including the head and neck, spine, chest, abdomen, pelvis, the upper and lower limbs, and paediatric imaging A companion website with self-assessment questions and image flashcards Perfect for radiography students and newly qualified practitioners, as well as practitioners preparing for MRI-based certification and examination, the Handbook of MRI Technique will also prove to be an invaluable addition to the libraries of students in biomedical engineering technology and radiology residents.
Handbook of Magnetic Resonance Spectroscopy In Vivo: MRS Theory, Practice and Applications
by John R. Griffiths Paul A. BottomleyThis handbook covers the entire field of magnetic Resonance Spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms-including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage
Handbook of Mammalian Metabolism of Plant Compounds (CRC Press Revivals)
by Ronald R. SchelineHandbook of Mammalian Metabolism of Plant Compounds provides an extensive survey of how mammals metabolize compounds found in higher plants. Information about these compounds is important to researchers in pharmacology, toxicology, medical and natural products chemistry, and food sciences. Although there is plenty of literature about mammalian metabolism of plant compounds, it is scattered, and summaries of specific plant compounds are often difficult to obtain. This book contains 11 chapters discussing the metabolic fate of individual plant compounds grouped according to chemical class. It also features structural formulas of the compounds and their metabolites, including probable pathways of metabolism. This book provides a convenient single-volume reference source that will benefit all researchers requiring this type of information.
Handbook of Management of Zoonoses
by Krishna Gopal Narayan Dharmendra Kumar Sinha Dhirendra Kumar SinghThis book reviews the etiology of major zoonotic diseases, their impact on human health, and control mechanisms for better management. It also examines factors influencing transmission, diagnosis, treatment, management, and prevention of zoonotic diseases caused by different human pathogens, including bacteria, viruses, fungi, protozoans, and parasites. It also introduces zoonoses with a wildlife reservoir and discusses different transmission modes, and factors that influence the epidemiology of zoonoses. It further discusses the holistic strategies for the cost-effective prevention and control of these zoonoses. Towards the end, the book also discusses infections that have spread from non-human primates to humans and strategies to improve disease control and elimination. This book is very useful for students, academicians, and researchers of veterinary sciences, veterinary medicine, and, veterinary public health.
Handbook of Marine Natural Products
by Ernesto Fattorusso Orazio Taglialatela-Scafati William H. Gerwick"Handbook of Marine Natural Products" takes a fresh approach to describing the major themes of research in this rapidly developing field. This two volume reference work begins with a section that provides a taxonomic survey of the secondary metabolites of diverse marine life including microbes, algae, and invertebrates. This is followed by a demonstration of the techniques and strategies employed in modern structure elucidation of complex natural products. The natural roles of marine natural products are then explored in a series of focused chapters which include the topics of symbiosis, anti-predation and antifouling, chemical interactions, and defence against UV stress. Various routes which facilitate the understanding of marine natural product biosynthesis are subsequently explained and these are followed by an extensive set of chapters on the biomedical potential of marine natural products. The latter portion of this section considers the technologies and scientific disciplines necessary for advancing bioactive marine natural product lead compounds into actual pharmaceuticals. The reference work finishes with a selection of chapters describing marine toxins and their impact on public health and seafood resources. Final thoughts presented at the end of the second volume focus on the future of this field of investigation and discovery research. This publication is presented as a reference handbook and general concepts are emphasized and illustrated with numerous interesting examples, graphical information, and a comprehensive index. "Handbook of Marine Natural Products" introduces students who are at advanced undergraduate and entry graduate student levels to this fascinating multidisciplinary field. It is an ideal desk companion for courses focusing on this contemporary area.
Handbook of Material Engineering in Nanobiomedicine and Diagnostics
by Pranjal Chandra Uday Pratap AzadThe book is about the application of nanotechnology in the field of medicine, with a focus on diagnosis and therapy. The first few chapters introduce the basics of material engineering and nanobiomedicine, followed by chapters on different types of engineered nanomaterials and their surface modification strategies for biomedicine. The book then covers the application of nanobiomedicines and nanodiagnostics in clinical settings, and how functionalized nanomaterials can be used in microfluidic biosensors and diagnosis devices. The latter half of the book discusses various nanobiomaterials used in cancer diagnosis and therapy, as well as regenerative medicine, infectious diseases, and bioimaging. The book concludes with a chapter on the commercial aspects of nanobiomedicines.
Handbook of Mathematical Methods in Imaging
by Otmar ScherzerThe Handbook of Mathematical Methods in Imaging provides a comprehensive treatment of the mathematical techniques used in imaging science. The material is grouped into two central themes, namely, Inverse Problems (Algorithmic Reconstruction) and Signal and Image Processing. Each section within the themes covers applications (modeling), mathematics, numerical methods (using a case example) and open questions. Written by experts in the area, the presentation is mathematically rigorous. The entries are cross-referenced for easy navigation through connected topics. Available in both print and electronic forms, the handbook is enhanced by more than 150 illustrations and an extended bibliography. It will benefit students, scientists and researchers in applied mathematics. Engineers and computer scientists working in imaging will also find this handbook useful.
Handbook of Measurement Error Models (Chapman & Hall/CRC Handbooks of Modern Statistical Methods)
by Grace Y. YiMeasurement error arises ubiquitously in applications and has been of long-standing concern in a variety of fields, including medical research, epidemiological studies, economics, environmental studies, and survey research. While several research monographs are available to summarize methods and strategies of handling different measurement error problems, research in this area continues to attract extensive attention. The Handbook of Measurement Error Models provides overviews of various topics on measurement error problems. It collects carefully edited chapters concerning issues of measurement error and evolving statistical methods, with a good balance of methodology and applications. It is prepared for readers who wish to start research and gain insights into challenges, methods, and applications related to error-prone data. It also serves as a reference text on statistical methods and applications pertinent to measurement error models, for researchers and data analysts alike. Features: Provides an account of past development and modern advancement concerning measurement error problems Highlights the challenges induced by error-contaminated data Introduces off-the-shelf methods for mitigating deleterious impacts of measurement error Describes state-of-the-art strategies for conducting in-depth research
Handbook of Media for Clinical Microbiology
by Ronald M. Atlas James W. SnyderWhile evolving molecular diagnostic methods are being heralded for the role they will play in improving our ability to cultivate and identify bacteria, fungi, and viruses, the reality is that those new methods are still beyond the technical and financial reach of most clinical laboratories. Most clinical microbiology laboratories still rely upon cu
Handbook of Media for Clinical and Public Health Microbiology
by Ronald M. Atlas James W. SnyderThe detection and/or isolation and identification of pathogenic microorganisms is critical for the laboratory diagnosis of infectious diseases. With growth-dependant methods providing reliable means for identifying pathogens, traditional culturing continues to play an integral role in the detection and characterization of known and "new" microbial
Handbook of Medical Aspects of Disability and Rehabilitation for Life Care Planning
by Richard Bowman Steven Barna Virgil Robert May IIIThis textbook is an essential resource for life care planners in understanding and assessing a range of medical disabilities, life care planning as a health care service delivery practice, certification under the International Commission on Health Care Certification, and the path to rehabilitation for mild to catastrophic injuries.Written by a team composed of expert physicians and doctoral-level practitioners, the book covers the key areas of traumatic injury and resultant disability that life care planners so often face. From acquired brain injury and spinal disorders to amputation, chronic pain, posttraumatic debilitating headaches, and plastic reconstructive surgery, the book provides a road map not only to the treatment options available but also the strategies that can lead to rehabilitation and a possible return to work. Each chapter also discusses possible complications, allowing a holistic perspective on each issue.Also including chapters on medical cost projection analysis and functional capacity evaluation, this is the complete text for both professionals in the fields of rehabilitation services and life care planning, as well as students training to qualify.