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Heart Failure
by Johann Bauersachs Javed Butler Peter SandnerClinical Heart Failure Management is designed to provide clinically useful information and guiding principles to assist physicians in the treatment of the typical heart failure patient who presented most often with complex co-morbidities. The authors have based their discussion of heart failure management on pathophysiologic principles, whenever possible. Evidence-based guidelines, including the 2016 ACC/AHA/HFSA Focused Update on New Pharmacologic Therapy for Heart Failure and the 2016 ESC heart failure diagnosis and treatment guidelines, are reviewed in detail. In addition, clinical guidance and prioritization of treatment options is also provided on managing patient who don't fall neatly into guideline directed therapy.
Heart Failure
by Jordan T. Shin Marc J. SemigranHeart Failure, Second Edition has been updated to provide the latest advancements in heart failure research. Supplemented by more than 200 high-quality figures and illustrations, the book helps cardiologists and emergency care physicians quickly and accurately identify the cause and severity of a patient's cardiac impairment.New topics in this edit
Heart Failure
by José Marín-GarcíaHeart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease. An authoritative contribution to the field, this book provides a detailed description of new findings and emerging methodologies, as well as a critical clinical evaluation of the complex HF syndrome and future therapies. Heart Failure: Bench to Bedside includes a primer on gene profiling and bioenergetics of the normal heart and a discussion of the molecular, genetic, biochemical and cellular techniques critical to understanding HF. Further chapters discuss cardiac remodeling, oxidative stress, and alterations in other organs and systems that are often associated with HF. This book thoughtfully evaluates current and forthcoming diagnostic techniques and therapies, pharmaceutical and pharmacogenomic-based individualized medicine, gene and cell-based therapies, and the search for new frontiers. Heart Failure: Bench to Bedside presents a clear view of up-to-date approaches to clinical diagnosis and treatment, as well as offering insightful critiques of original and creative scientific thoughts on post-genomic HF research.
Heart Failure
by Richard L. MabryWhen her fiancé's dangerous secretsturn her work upside down, a beautiful doctor must choose between her ownsafety and the man she loves--and thought she knew. Dr. Carrie Markham's heart was brokenby the death of her husband two years ago. Now, just as her medical practice istaking off, her fresh engagement to paralegal Adam Davidson seems almost toogood to be true . . . until a drive-by shooting leaves Carrie on the floor ofhis car with glass falling around her. When he confesses that Adam isn't hisreal name and that he fled the witness protection program, Carrie is left withan impossible choice: should she abandon the fiancé she isn't sure she reallyknows, or accept his claim of innocence and helphim fight back against this faceless menace? While Carrie struggles to decidewhether to follow her heart or her head, the threats against them continue toescalate. Her life--as well as Adam's--depends on making the right choice . . .and the clock is ticking.
Heart Failure (Cardiovascular Medicine)
by David S. Feldman Paul MohacsiThis textbook offers an up-to-date, user-friendly guide on the evaluation, diagnosis and treatment of heart failure. Each chapter is dedicated to providing comprehensive coverage of every aspect of heart failure from cardiac signs and symptoms through imaging and the genetic basis for disease to surgery, interventions, treatment and preventative cardiology. Heart Failure provides the trainee and practising cardiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients with a valuable resource featuring extensive guidance on the diagnosis and management of a range of conditions related to heart failure.
Heart Failure Management: The Neural Pathways
by Edoardo Gronda Emilio Vanoli Alexandru CosteaThis book describes the most recent insights into heart failure and the role played by autonomic nervous system pathophysiology in it, discussing the therapeutic implications. While current therapeutic approaches are able to control the effects of excessive adrenergic activation in heart failure syndrome, the underlying abnormalities of adrenergic control remain unaltered and can still cause progression to unmanageable end-stage heart failure. New therapeutic pathways are therefore being explored with a view to developing interventions that can directly modulate adrenergic over-activity and restore a more appropriate balance in neural control of the cardiovascular system. The book opens by examining current heart failure therapies. Advances in our understanding of autonomic regulation/dysregulation in heart failure are then discussed in detail, in the context of the search for more effective therapies. A concluding section addresses the role of autonomic nervous system denervation in heart failure. The authors are top scientists from leading research centers.
Heart Failure Updates
by John Jv McMurray Marc A PfefferGiven the ever-advancing development of new pharmacological agents to treat heart conditions, clinicians could use a practical report on newly available treatments. The authors here address that need, profiling every pharmacological therapy in use to date for the treatment of heart failure. Renowned as experts in the field, these prominent academic
Heart Failure and Palliative Care: A Team Approach, Second Edition
by Richard Lehman Tiny Jaarsma Miriam Johnson Karen HoggThis book is a guide to help clinicians caring for people with advanced heart failure develop a team approach for a group of people who, despite the increased awareness, remains disadvantaged in accessing support to help them live with, and support them as they die from, this serious illness.
Heart Failure in Adult Congenital Heart Disease (Congenital Heart Disease in Adolescents and Adults)
by Lorna Swan Alexandra A. FrogoudakiThis book sheds new light on the diagnosis and treatment of Heart Failure in adult patients with congenital heart disease. This is a rapidly growing clinical issue for this group of patients and the clinical teams caring for them. The book highlights the major clinical dilemmas in diagnosing heart failure in patients with a lifelong cardiac condition and describes in details the utility of biomarkers, complex imaging and functional tests, e.g. the cardiopulmonary exercise testing. A step-wise approach to treatment is described from drug therapy through to devices and transplantation. As such, the book offers an essential guide for cardiologists and cardiac surgeons looking to optimize the management of patients with delicate physiology and complex disease.
Heart Failure in Clinical Practice
by Michael Y. HeneinHeart Failure in Clinical Practice provides a toolkit for clinicians to guide them in the diagnosis and treatment of patients with suspected heart failure. Algorithms and flow diagrams are included to give the reader an illustrated snapshot of the decisions involved in the management of these patients.
Heart Failure in Congenital Heart Disease:
by Robert. E ShaddyThis book will provide both an evidence base and practical recommendations for the treatment of patients with congenital heart disease. It will be a resource to all health care providers, including pediatric cardiologists, pediatric intensivists, pediatric heart surgeons, fetal specialists, maternal fetal medicine specialists, neonatologists, nurses, advanced practice nurses, in addition to trainees in the field. It will summarize world knowledge on the topic of heart failure in patients with congenital heart disease. It will provide an in depth analysis of the current methods of diagnosis and treatment of heart failure. Now that surgical results are at record success rates, more patients with congenital heart disease are surviving, and thus at risk for sequelae from their disease, including heart failure. It will provide evidence based and practical recommendations to the practitioner for the management of heart failure signs and symptoms.
Heart Failure: An Essential Clinical Guide
by Andreas P. Kalogeropoulos, MD, MPH, PhD, FACC, FHFSA, FASEThis "patient-oriented" book was written as a meeting ground for practicing clinicians, allied health professionals, and clinical researchers to provide a practical guide for the contemporary assessment and management of patients with heart failure and cardiomyopathy. It revolves around broad patient scenarios to elegantly (or expertly) guide diagnostic and management strategies. Combining the talents of over one-hundred experts in the field, the book also endeavors to challenge the reader with areas of current controversies and opportunities for clinical investigation with the goals of both orienting clinicians and stimulating their research passions. Key Features Provides practical guidance based on real-life heart failure scenarios Discusses both acute and chronic care patient-oriented scenarios Covers up-to-date and novel concepts in heart failure Features the perspectives of current debates and controversies in heart failure Highlights the opportunities for research in this field
Heart Failure: Volume 3 (Advances in Experimental Medicine and Biology #1067)
by Md. Shahidul Islam“Heart Failure: From Research to Clinical Practice” contains chapters that describe the current views on the biological mechanisms, clinical assessment, diagnosis and evidence-based treatments of the condition. Topics in this volume range from basic research at cell and molecular level to patient care in everyday clinical practice and provide essential background information and analyses of recent advances for a deeper understanding of the issues involved. With contributions from international experts in their specified fields and are suitable for both beginners and more advanced readers. This volume includes not only the essential information for clinical practice but also the latest information from the contemporary guidelines and the recommendations from leading societies. It also covers ongoing research and puts forward new hypotheses that can be tested in future research. This comprehensive volume will provide a valuable resource for both research students and expert clinicians.
Heart Genomics (Translational Bioinformatics #16)
by Hong Jiang Ming LiuThis book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a series of important breakthroughs in various heart diseases. Applying unbiased genomics, combined with a disease-focused and hypothesis-driven approach, represents a promising way to advance our understanding of cardiac diseases. The book offers an important reference work on introducing genomics in heart disease for all scientists and graduate students whose work involves genomics and cardiology, as well as for clinical physicians.
Heart Healers
by James S ForresterOne Australian dies from heart disease every twelve minutes. But hundreds of thousands have lived thanks to the greatest medical breakthrough of our lives.World-renowned cardiologist Dr James Forrester tells the dramatic story of the misfits, mavericks and rebels who defied the accumulated scientific wisdom of the day to begin conquering heart disease. In The Heart Healers, he describes the risks these rebels took with their own lives and the lives of others to heal the most elemental of human organs.
Heart Mechanics: Magnetic Resonance Imaging—Advanced Techniques, Clinical Applications, and Future Trends
by El-Sayed H. IbrahimBased on research and clinical trials, this book details the latest research in magnetic resonance imaging (MRI) tagging technology related to heart mechanics. It covers clinical applications and examines future trends, providing a guide for future uses of MRI technology for studying heart mechanics.
Heart Mechanics: Magnetic Resonance Imaging—Mathematical Modeling, Pulse Sequences, and Image Analysis
by El-Sayed H. IbrahimMRI techniques have been recently introduced for non-invasive qualification of regional myocardial mechanics, which is not achievable with other imaging modalities. Covering more than twenty-three years of developments in MRI techniques for accessing heart mechanics, this book provides a plethora of techniques and concepts that assist readers choose the best technique for their purpose. It reviews research studies and clinical trials that implemented MRI techniques for studying heart mechanics.
Heart Proteomics
by Fernando VivancoThe use of proteomics to study complex diseases such as cardiovascular disease, the leading cause of death in developed countries, has grown exponentially in recent years. Proteomics is a rapidly expanding investigation platform in cardiovascular medicine and is becoming integrated and incorporated into cardiovascular research. The proteomics field continues to develop with major improvements in mass spectrometry instrumentation, methodology and data analysis. Heart Proteomics: Methods and Protocols complies a selection of techniques and methods that target the numerous processes implicated in the pathophysiology of heart. Chapters cover protocols and updated methods in the heart proteomic area with a particular focus on MS-based methods of protein and peptide quantification and the analysis of posttranslational modifications as well as descriptions of system biology approaches, which provide a better understanding of normal and pathological processes. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Heart Proteomics: Methods and Protocols is a representative selection of methods that will prove to be a useful resource for experienced proteomics practitioners and newcomers alike.
Heart Rate Variability
by Gernot ErnstThis book not only discusses clinical applications, but also links HRV to systems biology and theories of complexity. This publication should be interesting for several groups of clinicians and scientists, including cardiologists, anesthesiologists, intensivists and physiologists. Heart Rate Variability is in principle easy and cheap, making it interesting for all kind of hospitals and private practice. The book will be an example of using translational medicine (bench to bedside) where newest theoretical results are linked to newest clinical research.
Heart Rate Variability (HRV) Signal Analysis: Clinical Applications
by Markad V. Kamath Mari A. Watanabe Adrian R.M. UptonOpen a Window into the Autonomic Nervous SystemQuantifying the amount of autonomic nervous system activity in an individual patient can be extremely important, because it provides a gauge of disease severity in a large number of diseases. Heart rate variability (HRV) calculated from both short-term and longer-term electrocardiograms is an ideal win
Heart Rate Variability Analysis with the R package RHRV (Use R!)
by Xosé A. Vila Leandro Rodríguez-Liñares Constantino Antonio García Martínez Abraham Otero Quintana María José Lado Touriño Jesús María Rodríguez Presedo Arturo José Méndez PenínThis book introduces readers to the fundamental concepts of Heart Rate Variability (HRV) and its most important analysis algorithms using a hands-on approach based on the open-source RHRV software. HRV refers to the variation over time of the intervals between consecutive heartbeats. Despite its apparent simplicity, HRV is one of the most important markers of autonomic nervous system activity and it has been recognized as a useful predictor of several pathologies. The book discusses all the basic HRV topics, including the physiological contributions to HRV, clinical applications, HRV data acquisition, HRV data manipulation and HRV analysis using time-domain, frequency-domain, time-frequency, nonlinear and fractal techniques. Detailed examples based on real data sets are provided throughout the book to illustrate the algorithms and discuss the physiological implications of the results. Offering a comprehensive guide to analyzing beat information with RHRV, the book is intended for masters and Ph.D. students in various disciplines such as biomedical engineering, human and veterinary medicine, biology, and pharmacy, as well as researchers conducting heart rate variability analyses on both human and animal data. The second edition of the book has been updated to RHRV version 5.0. This version introduces a functionality to perform heart rate variability analysis on entire populations. This functionality automates and streamlines both the calculation of HRV indices in the time, frequency, and nonlinear domains, as well as the subsequent statistical analysis.
Heart Rate and Rhythm
by Michael C. Sanguinetti Onkar N. Tripathi Ursula RavensPathological heart rhythms are a major health issue. In this book experts from various fields provide an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms. Individual chapters cover a full range of topics, including the ionic basis of pacemaking, the role of specific channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ handling in response to disease, computer modeling of the action potentials of pacemaker and working cardiomyocytes, genetic and molecular basis of inherited arrhythmias and a review of established and novel antiarrhythmic agents. Due to the key importance of the specialized pacemaker cells and tissue (sinoatrial and atrioventricular nodes) in maintaining heart rate and rhythm, special emphasis is placed on the peculiar electrophysiology of these cells.
Heart Rate and Rhythm: Molecular Basis, Pharmacological Modulation and Clinical Implications
by Onkar N. Tripathi Ursula Ravens T. Alexander QuinnThis completely updated and expanded 2nd Edition provides all the information needed in order to understand the complex molecular, cellular and genetic mechanisms that underlie normal and abnormal cardiac rhythms. Its goal is to help physiologists and clinicians alike develop better preventive and treatment strategies. The respective chapters cover a broad range of topics, including the role of specific ion channels and transporters, gap junctions, intracellular Ca2+ handling in pacemaker activity, impulse conduction, and the activity of atrial and ventricular myocardium. Special emphasis is placed on the unique electrophysiology of specialized pacemaking cells and conducting fibers. In turn, several types of inherited and acquired ventricular arrhythmias are presented in detail. Clinicians will especially appreciate the updated information on even common disorders like atrial fibrillation and their impacts on human physiology. In closing, the book goes “one step further” and considers future prospects, e.g. novel antiarrhythmic agents and new concepts like optogenetics, in the context of heart rate regulation. Accordingly, it offers readers a solid reference guide to everything they need to know about human heart rate and rhythm.
Heart Rhythm Disorders: History, Mechanisms, and Management Perspectives
by J. Anthony GomesThis engaging book covers a multitude of topics related to heart rhythm disorders (HRDs) and uniquely familiarizes readers with the development of treatment modalities over the past several decades, including the evolution of anti-arrhythmic drugs, pacemakers, defibrillators, and catheter ablation. Organized in ten sections, this title serves as both an archival and a contemporary resource for clinicians. The first section describes the discovery of the circulatory system by William Harvey in 1628 and outlines the development and understanding of HRD since the advent of intra-cardiac electrophysiology. Subsequent sections discuss the historical evolution of abnormal heart rhythms, such as supra and ventricular rhythms and sudden cardiac death, their treatment with drugs, surgery, pacemakers, implantable defibrillators and catheter ablation. Section nine offers a fascinating narration of the clinical evolution of overcoming heart attacks and its impact on HRDs. The final section explores potential new frontiers in HRD and the factors that may contribute to the prospective rise of cardiovascular diseases. A ground-breaking and invaluable addition to the clinical literature, Heart Rhythm Disorders: History, Mechanisms and Management Perspectives details the pervasive nature of cardiovascular diseases in human history, their ramifications, and their projected effects on at-risk demographic populations and human health in general.
Heart Shock: Diagnosis and Treatment of Trauma with Shen-Hammer and Classical Chinese Medicine
by Ross Rosen Dr Leon HammerThis book describes in detail the effects and ongoing impacts of trauma on the body and mind and provides the 'missing piece' in the treatment of these stubborn conditions that every practitioner confronts. Heart Shock refers to the systemic impact that emotional and/or physical trauma has on one's physiology and psychology, interfering with one's ability to heal, and also directly attributable to a host of progressive pathology. Synthesizing the teachings of Jeffrey Yuen and the Shen-Hammer lineage and focusing heavily on psychology, Ross Rosen addresses how to identify, diagnose, and treat Heart Shock from multiple perspectives, providing a multi-faceted approach to treatment, including all the acupuncture channel systems, herbal medicine and the use of essential oils. The approach presented can also be expanded to treat any condition or disease process.