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Imaging and Focal Therapy of Early Prostate Cancer
by Thomas J. PolascikImaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy, ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer.
Imaging and Imagining the Fetus: The Development of Obstetric Ultrasound
by Malcolm Nicolson John E. FlemingHow engineers and clinicians developed the ultrasound diagnostic scanner and how its use in obstetrics became controversial.To its proponents, the ultrasound scanner is a safe, reliable, and indispensable aid to diagnosis. Its detractors, on the other hand, argue that its development and use are driven by the technological enthusiasms of doctors and engineers (and the commercial interests of manufacturers) and not by concern to improve the clinical care of women. In some U.S. states, an ultrasound scan is now required by legislation before a woman can obtain an abortion, adding a new dimension to an already controversial practice. Imaging and Imagining the Fetus engages both the development of a modern medical technology and the concerted critique of that technology.Malcolm Nicolson and John Fleming relate the technical and social history of ultrasound imaging—from early experiments in Glasgow in 1956 through wide deployment in the British hospital system by 1975 to its ubiquitous use in maternity clinics throughout the developed world by the end of the twentieth century. Obstetrician Ian Donald and engineer Tom Brown created ultrasound technology in Glasgow, where their prototypes were based on the industrial flaw detector, an instrument readily available to them in the shipbuilding city. As a physician, Donald supported the use of ultrasound for clinical purposes, and as a devout High Anglican he imbued the images with moral significance. He opposed abortion—decisions about which were increasingly guided by the ultrasound technology he pioneered—and he occasionally used ultrasound images to convince pregnant women not to abort the fetuses they could now see.Imaging and Imagining the Fetus explores why earlier innovators failed where Donald and Brown succeeded. It also shows how ultrasound developed into a "black box" technology whose users can fully appreciate the images they produce but do not, and have no need to, understand the technology, any more than do users of computers. These "images of the fetus may be produced by machines," the authors write, "but they live vividly in the human imagination."
Imaging and Interventional Radiology for Radiation Oncology (Medical Radiology)
by Regina G. H. Beets-Tan Wim J. G. Oyen Vincenzo ValentiniThis book, edited by leading experts in radiology, nuclear medicine, and radiation oncology, offers a wide-ranging, state of the art overview of the specifics and the benefits of a multidisciplinary approach to the use of imaging in image-guided radiation treatments for different tumor types. The entire spectrum of the most important cancers treated by radiation are covered, including CNS, head and neck, lung, breast, gastrointestinal, genitourinary, and gynecological tumors. The opening sections of the book address background issues and a range of important technical aspects. Detailed information is then provided on the use of different imaging techniques for T staging and target volume delineation, response assessment, and follow-up in various parts of the body. The focus of the book ensures that it will be of interest for a multidisciplinary forum of readers comprising radiation oncologists, nuclear medicine physicians, radiologists and other medical professionals.
Imaging and Pathology of Pancreatic Neoplasms
by Mirko D'Onofrio Paola Capelli Paolo PederzoliAlthough interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example. Diagnosis depends on the structure of the pancreatic lesion, which can be directly visualized on US, CT or MR images. This atlas, which encompasses both the imaging and the pathology of pancreatic neoplasms, will therefore be invaluable in enabling radiologists and sonographers to understand the underlying pathology and in allowing pancreatic pathologists to understand the imaging translation. The emphasis in the atlas is very much on the pathological and imaging appearances, with most of the text concentrated at the beginning of the chapters. A comprehensive overview is provided of typical and atypical presentations and diverse aspects of common and uncommon pancreatic neoplasms, including ductal adenocarcinoma, neuroendocrine neoplasms, intraductal papillary mucinous neoplasms, cystic neoplasms, metastases and lymphoma.
Imaging and Pathology of Pancreatic Neoplasms: A Pictorial Atlas
by Mirko D’Onofrio Paola Capelli Paolo PederzoliThe second edition of this atlas focuses on imaging methods and techniques, new diagnostic concepts and therapeutic approaches in management of pancreatic neoplasms. Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, less is known about it than about, for example, liver pathology. Diagnosis depends on the structure of the pancreatic lesion, which can be directly visualized in US, CT or MR images.The book’s focus is very much on the imaging and pathological appearances, with most of the text concentrated at the beginning of the book followed by images gallery. A comprehensive overview is provided of typical and atypical presentations and diverse aspects of common and rare pancreatic tumors, including ductal adenocarcinomas with dedicated chapter to ductal adenocarcinoma downstaging, neuroendocrine neoplasms, cystic pancreatic neoplasms and intraductal papillary mucinous neoplasms. The Verona “Pancreas Centre,” the first institute of its kind in Italy and one of very few in the world, pursues an interdisciplinary approach to treating the problems of this organ, focusing on the patient, on research, and on teaching. A dedicated center that can look back on 40 years of tradition, many of its respected specialists have made essential contributions in surgery, gastroenterology, oncology, pathology, and radiology. Given its scope, this atlas will be an invaluable asset, helping radiologists understand the underlying pathology and helping pancreatic pathologists understand the imaging translation.
Imaging and Quantifying Neuronal Autophagy (Neuromethods #171)
by Ben Loos Esther WongThe volume aims to explore the dynamic nature of the autophagy pathway, and the latest techniques that allow researchers to capture and quantify this process in neurons. The chapters in this volume cover topics such as fundamental, historical, and functional approaches that began in baker’s yeast; Saccharomyces cerevisiae; the role of both electron microscopy and live-cell imaging using fluorescently tagged autophagy proteins; and the rate of puncta appearance and its correlation with the rate of autophagosome formation. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Imaging and Quantifying Neuronal is a valuable resource that provides insights into the power of microscopy tools, live-cell imaging, and photoactivation and correlative techniques.
Imaging and Technology in Urology
by Steve Payne Kieran O'Flynn Ian EardleyImaging and Technology: Principles and Clinical Applications is a practical and user-friendly consolidated source book for urologists, and urologists in training, regarding the basic science of imaging modalities used on a day-to-day basis in urological practice. Similarly, the intention is to provide an introduction to the technology that is used in the practice of urological surgery and the management of urological patients in the clinical setting. This knowledge level is appropriate for certification for independent consultant practice in urology in the UK. The book is also valuable to urologists and urological trainees outside of the UK and in other surgical specialities.
Imaging and Technology in Urology
by Sotonye Tolofari Dora Moon Benjamin Starmer Steve PayneThis book offers a new edition of the hugely successful title, Imaging & Technology in Urology--Principles and Clinical Applications edited by Steve Payne, Ian Eardley, Kieran O'Flynn in 2012. Essential reading for preparation of exit exams in Urology, it is used worldwide by exam candidates. Fully updated in essential areas of the book following on from recent developments in the last decade, it helps give preparation to candidates. The most comprehensive and reliable source of information on this particular topic.
Imaging and Tracking Stem Cells: Methods and Protocols (Methods in Molecular Biology #2150)
by Kursad TurksenThis fully updated book brings together protocols to arm stem cell biologists with tools and approaches to continue uncovering the intricacies and regulatory mechanisms underlying stem cell biology. Through various models and organ systems, the volume reflects the numerous recent advances in cell lineage and lineage tracking. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Imaging and Tracking Stem Cells: Methods and Protocols, Second Edition is an ideal guide for novices and experts alike who are working to expand our knowledge in the field of stem cells.
Imaging and Urodynamics of the Lower Urinary Tract
by Uday PatelThis book is a practical text covering the imaging techniques and the range of urodynamic problems the trainee and practising urologist is likely to encounter including; congenital abnormalities of the bladder, functional abnormalities of the bladder, intraluminal abnormalities and staging of bladder cancer. The urethra and lower urinary tract are also dealt with. Although these disorders are covered in the major reference works, there is a need for a practical, accessible, user friendly text which provides clear and unambiguous guidelines on the best practice available.
Imaging and Visualization in The Modern Operating Room
by Yuman Fong Pier Cristoforo Giulianotti Jason Lewis Bas Groot Koerkamp Thomas ReinerThis text provides a state of the art overview of tools for guiding surgeons in the modern operating room. The text explains how many modalities in the current armamentarium of radiologic imaging have been brought to the operating room for real time use. It also explains the current use of near infrared, fluorescent, and chemo-luminescent imaging to guide minimally invasive and open surgery to improve outcome. The book is separated into two sections. The first, discusses the biologic principles that underlie novel visualization of normal organs and pathology. The currently available equipment and equipment anticipated in the near future is covered. The second section summarizes current clinical applications of advanced imaging and visualization in the OR. Novel means of visualizing normal anatomic structures such as nerves, bile duct, and vessels that enhance safety of many operations are covered. Novel biologic imaging using radio-labeled and fluorescent-labeled molecular probes that allow identification of inflammation, vascular abnormalities, and cancer are also discussed. Authored by scientists who pioneer research in optics and radiology, tool makers who use this knowledge to make surgical equipment, and surgeons who innovate the field of surgery using these new operative tools, Imaging and Visualization in the Modern Operating Room is a valuable guide for surgeons, residents and fellows entering the field.
Imaging Atlas of Ophthalmic Tumors and Diseases
by J. Matthew DebnamThis atlas describes an array of tumors and diseases that affect the orbit and associated cranial nerves. Often lacking in radiology residency and fellowship training is teaching of the anatomy of the orbit and cranial nerves, as well as the imaging appearance of orbital tumors and diseases that affect these regions. This atlas fills this gap of knowledge with tumors and diseases encountered and treated at MD Anderson Cancer Center, providing a review of the imaging anatomy and the appearance of the tumors and diseases that should aid in formatting a differential diagnosis. The text consists of ten chapters divided into separate anatomic sections followed by an eleventh chapter describing the treated orbit and tumor recurrence. Each of the first ten chapters begins with a description of the relevant anatomy, labeled CT and MRI images and drawings to highlight important anatomic considerations. This is an ideal guide for practicing general radiologists, neuroradiologists and trainees, as well as ophthalmologists, head and neck surgeons, neurosurgeons, medical and radiation oncologists, and pathologists who interpret or review orbital images as part of their daily practice.
Imaging Atlas of the Normal Gallbladder and Its Variants
by J.W. MeilstrupAn in-depth knowledge of the wide spectrum of normal gallbladder appearances is vital to appropriate clinical workup and the correct diagnosis of patients with upper abdominal symptoms. This book covers the range of appearances of the normal gallbladder and its variants, including discussions of anatomy, embryology, and imaging techniques to promote a better understanding of the subject. Anomalies of number, location, and form are each addressed in separate chapters, and discussions of imaging artifacts of the gallbladder and pseudolesions, which can mimic gallbladder disease, are also included. A short chapter on the appearance of the fetal gallbladder is included to round out this comprehensive volume.
Imaging Biomarkers in Epilepsy
by Andrea Bernasconi Neda Bernasconi Matthias KoeppEpilepsy is a prevalent and serious neurological disorder. This vital textbook addresses the role of neuroimaging as a unique tool to provide in vivo biomarkers aimed at furthering our understanding of causes and consequences of epilepsy in a day-to-day clinical context. Unique in its approach, this translational book presents a critical appraisal of advanced pre-clinical biomarkers that allows capturing epileptogenesis at molecular, cellular, and neuronal system levels. The book is divided into four sections. Part I includes a series of chapters focused on imaging of early disease stages. Part II discusses lesion detection and network analysis methods. Part III focuses on imaging methods used to predict response to antiepileptic drugs and surgery. Finally, Part IV presents imaging techniques used to evaluate disease consequence.
Imaging Brain Diseases: A Neuroradiology, Nuclear Medicine, Neurosurgery, Neuropathology and Molecular Biology-based Approach
by Serge Weis Michael Sonnberger Andreas Dunzinger Eva Voglmayr Martin Aichholzer Raimund Kleiser Peter StrasserThis book illustrates in a unique way the most common diseases affecting the human nervous system using different imaging modalities derived from radiology, nuclear medicine, and neuropathology. The features of the diseases are visualized on computerized tomography (CT)-scans, magnetic resonance imaging (MRI)-scans, nuclear medicine scans, surgical intraoperative as well as gross-anatomy and histology preparations. For each disease entity, the structural changes are illustrated in a correlative comparative way based on the various imaging techniques. The brain diseases are presented in a systematic way allowing the reader to easily find the topics in which she or he is particularly interested. In Part 1 of the book, the imaging techniques are described in a practical, straightforward way. The morphological built-up of the normal human brain and its vascular supply are presented in Part 2. The chapters of the subsequent Parts 3 to 10 deal with the following diseases involving the nervous system including: hemodynamic, vascular, infectious, neurodegenerative, demyelination, epilepsy, trauma and intoxication, and tumors. The authors incite the clinician to see the cell, the tissue, the organ, the disorder by enabling him to recognize brain lesions or interpreting histologic findings and to correlate this knowledge with molecular biologic concepts. Thus, this book bridges the gap between neuro-clinicians, neuro-imagers and neuro-pathologists. The information provided will facilitate the understanding of the disease processes in the daily routine work of neurologists, neuroradiologists, neurosurgeons, neuropathologists, and all allied clinical disciplines.
Imaging Brain Function With EEG
by Rodrigo Quian Quiroga Walter FreemanThe scalp and cortex lie like pages of an open book on which the cortex enciphers vast quantities of information and knowledge. They are recorded and analyzed as temporal and spatial patterns in the electroencephalogram and electrocorticogram. This book describes basic tools and concepts needed to measure and decipher the patterns extracted from the EEG and ECoG. This book emphasizes the need for single trial analysis using new methods and paradigms, as well as large, high-density spatial arrays of electrodes for pattern sampling. The deciphered patterns reveal neural mechanisms by which brains process sensory information into precepts and concepts. It describes the brain as a thermodynamic system that uses chemical energy to construct knowledge. The results are intended for use in the search for the neural correlates of intention, attention, perception and learning; in the design of human brain-computer interfaces enabling mental control of machines; and in exploring and explaining the physicochemical foundation of biological intelligence.
Imaging Complications of Gastrointestinal and Biliopancreatic Endoscopy Procedures
by Massimo TonoliniThis practically oriented book illustrates and reviews the imaging appearances of the common and unusual complications that may occur after upper gastrointestinal endoscopy, endoscopic retrograde cholangiopancreatography (ERCP), colonoscopy, polypectomy, stricture dilatation, and stent placement. Detailed attention is devoted to the assessment of complications after percutaneous endoscopic gastrostomy (PEG) positioning, the issues associated with video capsule retention after small bowel capsule endoscopy, and iatrogenic colonic perforations in patients with inflammatory bowel diseases. A dedicated chapter explains the expanding role and possibilities of interventional radiology in the treatment of such complications. The pivotal role of multidetector computed tomography (CT) in the detection and grading of endoscopy-specific iatrogenic complications is highlighted. In addition, normal imaging appearances are presented for comparison and information is provided on such aspects as the mechanisms of complications, patient- and procedure-related risk factors, clinical features, and treatment options according to established guidelines. The book will be invaluable in enabling gastroenterologists, general surgeons, and radiologists to diagnose and treat endoscopy-related complications in timely fashion.
Imaging Coronary Arteries
by David A. Dowe Massimo Fioranelli Paolo PavoneIn non-fatal cases, cardiovascular diseases are associated with a decreased quality of life as well as a substantial economic burden to society. Most sudden cardiac events are related to the complications of a non-stenosing marginal plaque. For this reason, the ability to properly identify the atherosclerotic plaque with rapid, non-invasive techniques is of utmost clinical interest in diagnostic workup and therapeutic planning of symptomatic patient. Nowadays CT produces high-quality images of the coronary arteries, in addition to defining their location and the extent of the atherosclerotic involvement. This new edition is enriched with two important additions. Firstly, dedicated chapters on intravascular ultrasound (IVUS), catheter angiography, and nuclear imaging have been included, with some discussions on theoretical techniques such as optical coherence tomography (OCT) and magnetic resonance imaging (MRI). Secondly, a completely new section comprising more than 70 clinical cases remarkably expands the horizons reached by the previous edition. This volume provides general practitioners and cardiologists with a basic understanding of the imaging techniques. For radiologists with no direct experience in cardiac imaging, the book serves as an important source of information on coronary pathophysiology and anatomy.
Imaging Coronary Atherosclerosis
by Stephen J. Nicholls Tim CroweFor over 50 years, coronary angiography has been the mainstay of diagnosing and quantifying the extent of coronary artery disease However appreciation of the inherent limitations of conventional angiography has led to a plethora of new imaging modalities, each with their relative strengths and potential pitfalls. Advances in these techniques have given clinicians, as well as researchers, an overwhelming amount of information and the need for thoughtful interpretation. This outstanding book provides a comprehensive overview of the current status of imaging of coronary atherosclerosis Covering the wide variety of available imaging modalities, the book provides state-of-the-art knowledge from leading authorities in each area In their discussion, the authors include both invasive and non-invasive modalities, including the gold standard coronary angiography, the growing field of IVUS, and novel techniques such as functional imaging, molecular imaging, and the integration of biomarkers. The key concepts and practical information given in this volume will provide the reader with the necessary understanding to choosing appropriate imaging studies and building confidence in their skill set with each.
Imaging Dementia: Essentials for Clinical Practice
by Massimo Filippi Federica AgostaThis book helps physicians select from among the currently available imaging tools, promoting the correct and cost-saving diagnosis and management of common dementias. Magnetic resonance (MR) and nuclear medicine techniques are routinely used to facilitate diagnosis, select therapies, provide information regarding the prognosis, and monitor therapy response in patients with cognitive impairment and dementia. Furthermore, the advent of quantitative MR techniques, such as diffusion-weighted imaging, perfusion imaging, etc. have opened up new opportunities to diagnose neurological diseases based on objective findings, and offer unique new insights into the main neurodegenerative diseases of the human brain. However, the practical value of various neuroimaging techniques in clinical practice has yet to be clearly defined, and their potential for future development is not yet fully appreciated.To help remedy the situation, this book offers practical and useful algorithms and rules that can be directly applied in the clinical setting. It provides concise content, together with a wealth of clinical case material.
Imaging Diagnostics in Pancreatic Cancer: A Clinical Guide (Clinical Gastroenterology)
by Naveen Anand Peter DarwinThis book provides a comprehensive, state-of-the-art overview of imaging modalities used in the diagnosis, staging, and management of pancreatic cancer. In addition to profiling the most commonly-used imaging modalities for pancreatic cancer, the text reviews recent advances in endoscopic ultrasound, staging characteristics utilized in determining appropriate treatment options, and reviews the role of imaging in pancreatic cancer screening in specialized patient populations. The book also spotlights the use of radiation therapy for pancreatic cancer in patients who cannot have surgery, as well as when fiducial marker placement should be considered in targeting a malignancy. Written by experts in the field, Imaging Diagnostics in Pancreatic Cancer: A Clinical Guide is a valuable resource for gastroenterologists, surgeons, oncologists, radiologists, and other practitioners who manage patients with pancreatic cancer.
Imaging Drug Action in the Brain
by Edythe D. LondonImaging Drug Action in the Brain is an outstanding reference that provides detailed methodological information and presents a current review of information obtained using various methods to delineate the neuroanatomy of drug action. It presents material covering selective lesioning and intracranial injections in intact animals. It examines various applications of receptor binding techniques and their importance in pharmacology. In vivo metabolic mapping studies to delineate the distributions of action of psychoactive drugs in animals are reviewed in detail. Imaging Drug Action in the Brain presents recent advances in extending these types of studies to human investigations, using positron emission tomography (PET) scanning and electrophysiological imaging techniques. Applications of immunocytochemical and molecular biology techniques in studies of drug action are explained. Imaging Drug Action in the Brain is the only book that encompasses all of these techniques with up-to-date examples of their applications. It is an essential resource for researchers in the fields of neuropharmacology, neuroanatomy, neurophysiology, and nuclear medicine.
Imaging Endocrine Diseases in Children
by Fred AvniThis book is a unique resource that will help pediatric radiologists, pediatricians, and pediatric endocrinologists to optimize the work-up and treatment of pediatric patients with endocrine disorders. Acclaimed experts in the field present and discuss the imaging findings obtained in disorders of the various endocrine systems, including the hypothalamo-pituitary axis, the thyroid and parathyroids, the adrenals, and the pancreas. Detailed advice is also provided on the assessment of bone growth and on imaging of the fetal glands, ambiguous genitalia, and the female pelvis in the context of precocious puberty. Throughout, care is taken to highlight characteristic findings and diagnostic clues. All of the currently used imaging techniques are covered, with clear explanation of their benefits and limitations. The informative text is supported by a wealth of high-quality illustrations, the large majority of them in color.
Imaging for Patient-Customized Simulations and Systems for Point-of-Care Ultrasound: International Workshops, BIVPCS 2017 and POCUS 2017, Held in Conjunction with MICCAI 2017, Québec City, QC, Canada, September 14, 2017, Proceedings (Lecture Notes in Computer Science #10549)
by M. Jorge Cardoso, Tal Arbel, João Manuel R.S. Tavares, Stephen Aylward, Shuo Li, Emad Boctor, Gabor Fichtinger, Kevin Cleary, Bradley Freeman, Luv Kohli, Deborah Shipley Kane, Matt Oetgen and Sonja PujolThis book constitutes the refereed joint proceedings of the International Workshop on Bio-Imaging and Visualization for Patient-Customized Simulations, BIVPCS 2017, and the International Workshop on Point-of-Care Ultrasound, POCUS 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Québec City, QC, Canada, in September 2017. The 12 full papers presented at BIVPCS 2017 and the 7 full papers presented at POCUS 2017 were carefully reviewed and selected. The papers feature research from complementary fields such as signal and image processing, mechanics, computational vision, mathematics, physics, informatics, computer graphics, bio-medical-practice, psychology and industry as well as ultrasound image systems applications.
Imaging for Pediatricians
by Antonio Martínez-Valverde Luisa Ceres-Ruiz María I. Martínez-LeónThe book, written by expert pediatricians and radiologists, is divided into ten chapters covering neurology, cardiology, neonatology, interventional radiology, the abdomen, the musculoskeletal system, the thorax, the genitourinary system, the fetus, and emergencies. Each chapter comprises ten cases that are presented in a standard way. After discussion of the disorder in question, four representative images are displayed and described with special attention to distinctive features. In addition, informative key references are provided, including a book or book chapter, a web link, and ten recent articles.