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Helicobacter pylori
by Nayoung KimThis book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection and recrudescence rate after H. pylori eradication, the effect of H. pylori and its eradication on the gastric microbiota and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. In addition, readers can understand the interaction between H. pylori and other gut microbiota during chronic infection and after H. pylori eradication. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.
Helicobacter pylori Research
by Steffen Backert Yoshio YamaokaThis book provides the currentupdated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori isa class I carcinogen and one of the most common infections in the world. Whilemost people colonized by H. pylori willremain asymptomatic, up to 20 % of them may develop serious gastroduodenaldisease such as peptic ulcers or gastric cancer. H. pylori isthe only known bacterium linked to the development of cancer and consequentlyis an important focus of research. Outstanding international experts fromdiverse scientific disciplines contribute here to give detailed insights intothe current understanding concerning the physiology and role of this pathogen. Both basic science and clinical research with actual practical consequences aretaken into account. The chapters target microbiology, epidemiology, genetics,biochemistry, interactions with the immune system, signal transduction,pathogenic mechanisms in the gastroduodenal mucosa, gastric diseasedevelopment, and therapy including antibiotics or probiotics treatment as wellas vaccination strategies. This book is an important reference not only forclinicians but also microbiologists. It provides in a single volume anup-to-date summary of our current knowledge of this microbe and the multipleways in which it impacts upon public health in all parts of the world.
Helicobacter pylori and Gastric Cancer (Current Topics in Microbiology and Immunology #444)
by Steffen BackertThis volume explores in detail the molecular biology, genetics and immunology of the bacterium Helicobacter pylori that causes serious gastric diseases such as gastric cancer. The book provides in-depth insights into the mechanisms of H. pylori-induced pathogenicity, gives an overview of how the bacterium colonizes the human gut, how it manages to persist in the body and which factors play a role in the development of H. pylori-induced gastric cancer. Furthermore, the interaction between the Gram-negative bacterium and the human gut microbiome is explored, and clinical management and treatment strategies to combat gastric cancer are discussed.Helicobacter pylori is an extremely successful pathogen that persistently colonizes the gut of about 50% of the world’s population. H. pylori and its human host share a long co-evolutionary relationship that dates back for at least last 100,000 years and possibly longer. Infection by this bacterium is a high-risk factor for the development of gastric diseases, including gastric cancer. Gastric cancer is associated with high morbidity and mortality and represents the 5th most common malignant tumour and the 4th leading cause of cancer-related death worldwide. H. pylori is the first bacterium that has been classified as a type-I carcinogen by the International Agency for Research on Cancer (IARC). Recent research progress identified crucial bacterial, host and environmental factors which control H. pylori-induced gastric malignancy. New studies also suggest that specific human germline mutations and other genetic aberrations have an important impact on H. pylori-induced pathology. In this volume, all these recently discovered mechanisms are reviewed in the light of gastric cancer development, and H. pylori epidemiology, virulence factors, immune evasion, pathophysiology, cancer signalling and novel therapeutic protocols are presented. This volume is aimed at researchers in the fields of immunology, genetics, microbiology and medicine who are interested in the detailed mechanisms of the pathogenicity of this carcinogenic stomach bacterium.
Helicobacter pylori in Human Diseases: Advances in Microbiology, Infectious Diseases and Public Health Volume 11 (Advances in Experimental Medicine and Biology #1149)
by Steffen Backert Shigeru KamiyaThis book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.
Hell and High Water: A blistering Swedish crime thriller, with the most original heroine you'll meet this year
by Christian UngeThe first in a new Swedish crime series featuring Tekla Berg, a fearless doctor with a remarkable photographic memory"A taut and blistering thriller with the most memorable protagonist ever. Christian Unge is in total control of his environment. It deserves to be huge" Imran Mahmood, author of You Don't Know Me"Watch your blood pressure! A tense and clever thriller" Lilja SigurðardóttirWith 85% per cent burns to his body and a 115% risk of dying, it's a miracle the patientis still alive.He only made it this far thanks to Tekla Berg, an emergency physician whose unorthodox methods and photographic memory are often the difference between life and death.Convinced that the fire was a terrorist attack - and that the patient was involved - the police are determined to question him. Almost as determined as those who would silence him at any cost. And while Tekla battles to keep him breathing, she can't shake the thought that something about him is strangely familiar . . .Tekla has always hidden her remarkable mind from her hospital colleagues, resorting to amphetamines to take the edge off the endless whirl of lucid memories. But now she'll need to call on all her wits as she's drawn into a mystery involving corrupt police, the godfather of the Uzbek mafia, and her beloved but wayward brother.Translated from the Swedish by George Goulding
Hell and High Water: A blistering Swedish crime thriller, with the most original heroine you'll meet this year
by Christian UngeThe first in a new Swedish crime series featuring Tekla Berg, a fearless doctor with a remarkable photographic memory"A taut and blistering thriller with the most memorable protagonist ever. Christian Unge is in total control of his environment. It deserves to be huge" Imran Mahmood, author of You Don't Know Me"Watch your blood pressure! A tense and clever thriller" Lilja SigurðardóttirWith 85% per cent burns to his body and a 115% risk of dying, it's a miracle the patientis still alive.He only made it this far thanks to Tekla Berg, an emergency physician whose unorthodox methods and photographic memory are often the difference between life and death.Convinced that the fire was a terrorist attack - and that the patient was involved - the police are determined to question him. Almost as determined as those who would silence him at any cost. And while Tekla battles to keep him breathing, she can't shake the thought that something about him is strangely familiar . . .Tekla has always hidden her remarkable mind from her hospital colleagues, resorting to amphetamines to take the edge off the endless whirl of lucid memories. But now she'll need to call on all her wits as she's drawn into a mystery involving corrupt police, the godfather of the Uzbek mafia, and her beloved but wayward brother.Translated from the Swedish by George Goulding & Sarah de Senarclens
Hello I Want to Die Please Fix Me: Depression in the First Person
by Anna Mehler PapernyAward-winning journalist Anna Mehler Paperny's stunning memoir chronicles with courageous honesty and uncommon eloquence her experience of depression and her quest to explore what we know and don't know about this disease that afflicts almost a fifth of the population--providing an invaluable guide to a system struggling to find solutions. As fascinating as it is heartrending, as outrageously funny as it is serious, it is a must-read for anyone impacted by depression--and that's pretty much everybody. Depression is a havoc-wreaking illness that masquerades as personal failing and hijacks your life. After a major suicide attempt in her early twenties, Anna Mehler Paperny resolved to put her reporter's skills to use to get to know her enemy, setting off on a journey to understand her condition, the dizzying array of medical treatments on offer and a medical profession in search of answers. Charting the way depression wrecks so many, she maps competing schools of therapy, pharmacology, cutting-edge medicine, the pill-popping pitfalls of long-term treatment, the glaring unknowns and the institutional shortcomings that both patients and practitioners are up against. She interviews leading medical experts across Canada and the US, from psychiatrists to neurologists, brain-mapping pioneers to family practitioners, and others dabbling in strange hypotheses--and shares compassionate conversations with fellow sufferers.Hello I Want to Die Please Fix Me tracks Anna's quest for knowledge and her desire to get well. Impeccably reported, it is a profoundly compelling story about the human spirit and the myriad ways we treat (and fail to treat) the disease that accounts for more years swallowed up by disability than any other in the world.
Hello New You: Eat Better, Drink Less, Exercise More
by Katherine BeboBeing healthy doesn’t have to be hard. Eating junk food, drinking too much and rarely (or barely) exercising – we’ve all been there. Sometimes you just need a bit of help, some practical advice and a few words of encouragement to get yourself back on track. Intended for anyone with a busy life, this handbook gets straight to the point, gathering together useful tips, motivational quotes and achievable steps towards a healthier body and a happier mind. No matter where you’re starting from or aiming for, there’s something here to spur you on, including:Dietary hacks to avoid overeating, improve sleep and reach your ideal weightGood guidance on fats and carbs, which are often misunderstoodAn honest look at how alcohol can affect your health (and your finances)Easy ways to reduce your alcohol consumptionClever ideas for matching your workout to suit your mood and scheduleSound advice on choosing exercises that keep you motivated
Hello Sleep: The Science and Art of Overcoming Insomnia Without Medications
by Jade WuA practical and compassionate guide to repairing your relationship with sleepFor the twenty-five million Americans who struggle with insomnia, each night feels like a battle with their racing minds instead of a blissful surrender into sleep. Hello Sleep is a guide for the tired but wired people who just want sleep to be easy. Dr. Jade Wu, an internationally recognized behavioral sleep medicine specialist, walks you through the science of how the brain sleeps (or doesn’t); shares stories from the clinic of real people’s journeys to better sleep; and lays out a step-by-step program for overcoming insomnia and letting go of sleeping pills. Using her years of clinical expertise, she problem-solves your common pitfalls, soothes your anxieties, and tailors recommendations for your special sleep circumstances (e.g., pregnancy, menopause, chronic pain, depression, etc.). Hello Sleep empowers the sleepless with the latest knowledge and most effective tools, allowing them to trust themselves and their own sleep again. It will answer these burning questions and more:• Why can’t I fall asleep even though I’m tired? How can I quiet my mind?• What should I do when I wake up at 2:00 A.M. and can’t get back to sleep?• Should I nap? What can I do about my fatigue during the day?• How do I get off sleep medications safely and without rebound insomnia?
Helminth Infections and their Impact on Global Public Health
by Fabrizio BruschiHelminths are long-lived multicellular organisms that have co-evolved with humans over many thousands of years They are responsible for infections which affect around one third of the human population, at global level. Despite the huge efforts in research during the last years, effective control of helminth infections is still far from optimal standards and the resulting diseases remain neglected. This book aims to give an up-date overview to the epidemiology (including molecular typing), specific biological, immunological and immunopathological aspects, diagnosis and perspectives of control of the most common helminth infections.
Helminth Infections and their Impact on Global Public Health
by Fabrizio BruschiThis is a thoroughly revised edition of a well-received reference work on helminthiases and their impact on worldwide public health. The carefully presented collection covers both common and neglected helminth infections. Readers will discover an up-date overview to helminth epidemiology (including molecular typing), specific biological, immunological and immunopathological aspects, diagnosis and latest perspectives of control. New contributions give particular attention to economic consequences of helminthiases, deworming programs and future public health approaches, as well as most recent findings in host immune responses. Helminths are long-lived multicellular organisms that have co-evolved with humans over many thousands of years. They are responsible for infections which affect around one fourth of the human population, at global level. Despite the huge efforts in research during the last years, effective control of helminth infections is still far from optimal standards and the resulting diseases remain neglected. The highly readable link of parasitological background and clinical application makes this book a valuable read not only for parasitologists but also physicians and medical students, health professionals as well as experts in public health issues.Moreover, all readers concerned with combating neglected parasitoses towards the Sustainable Development Goal SDG 3 (Good Health and Well-being) will understand the significance of this renewed volume.
Help Heal Yourself from Cancer: Partner Smarter with Your Doctor, Personalize Your Treatment Plan, and Take Charge of Your Recovery
by William Sears Martha SearsCancer can make you feel powerless. Survival rate statistics can leave you feeling helpless and afraid. But you are a person, not a percentage. And you are not powerless—you have the ability to help yourself heal. In Help Heal Yourself from Cancer, cancer survivors and trusted medical professionals Bill and Martha Sears help you go from patient to partner in your cancer-healing journey. They outline the steps you can take, both in working with your cancer-care providers and on your own, to maximize your chances of not just beating cancer, but thriving in its wake. This comprehensive guide will help you: Develop a conquer-cancer mindset. The science is clear: cancer healing begins with the brain. Believing you will heal is the first step. Personalize your treatment plan. Find out what tests to ask for, which advice to pay attention to (and what to ignore), and how to talk to your oncologist about designing a plan that&’s perfectly tailored to you and your cancer. LEAN in to supporting your immune system. Learn how to best support your natural cancer-fighting army through lifestyle, exercise, and nutrition—giving chemotherapy and radiation the best chance of success. With eye-catching illustrations to boost understanding and special sections on breast, colon, lung, and brain cancers, this book gives you the tools you need to stop fearing your cancer and start boosting your immune system, fine-tuning your treatment plan, and taking charge of your healing—all so you can ultimately Help Heal Yourself from Cancer.
Help Me Live, Revised: 20 Things People with Cancer Want You to Know
by Lori HopeAlmost all of us know someone with cancer. And, of course, we want nothing more than to offer comfort and support, and foster hope. But we don&’t always know how—and may feel uncomfortable asking. Following her own treatment for cancer, Lori Hope created a survey for cancer survivors addressing issues they wanted their families, friends, and caregivers to understand. The results of the newly expanded survey are presented with honesty, insight, and humor, and complemented by scores of compelling personal stories from survivors of diverse ages and backgrounds. If you are a caregiver, Help Me Live will help you communicate more effectively and respond more compassionately. And if you are a survivor, it will help you feel validated, empowered, and, ultimately, hopeful.
Help Your Teenager Beat an Eating Disorder
by Daniel Le Grange James LockIf your teenager shows signs of having an eating disorder, you may hope that, with the right mix of love, encouragement, and parental authority, he or she will just "snap out of it." If only it were that simple. To make matters worse, certain treatments assume you've somehow contributed to the problem and prohibit you from taking an active role. But as you watch your own teen struggle with a life-threatening illness, every fiber of your being tells you there must be some part you can play in restoring your child's health. In Help Your Teenager Beat an Eating Disorder, James Lock and Daniel Le Grange--two of the nation's top experts on the treatment of eating disorders--present compelling evidence that your involvement as a parent is critical. In fact, it may be the key to conquering your child's illness. Help Your Teenager Beat an Eating Disorder provides the tools you need to build a united family front that attacks the illness to ensure that your child develops nourishing eating habits and life-sustaining attitudes, day by day, meal by meal. Full recovery takes time, and relapse is common. But whether your child has already entered treatment or you're beginning to suspect there is a problem, the time to act is now. This book shows how.
Help Your Teenager Beat an Eating Disorder
by James Lock Daniel Le GrangeEating disorders are among the most dangerous--and misunderstood--adolescent mental health problems. When your teenager shows signs of an eating disorder, where can you turn? Now in a revised and updated third edition, this trusted resource helps you separate fact from myth and play an active role in your child's recovery. Treatment experts James Lock and Daniel Le Grange spell out what parents need to know about anorexia nervosa, bulimia nervosa, binge-eating disorder, and avoidant/restrictive food intake disorder (ARFID). They guide you step by step to find the right care, monitor your teen's eating and exercise habits, manage family meals, end weight-related power struggles, and team successfully with professionals. The revised third edition incorporates key research and treatment advances, new vignettes, and expanded coverage of ARFID. When families work together to get the most out of treatment and prevent relapse, eating disorders can be beat--this book is your essential roadmap.
Help Your Teenager Beat an Eating Disorder, Second Edition
by Daniel Le Grange James LockTens of thousands of parents have turned to this compassionate guide for support and practical advice grounded in cutting-edge scientific knowledge. Top experts James Lock and Daniel Le Grange explain what you need to know about eating disorders, which treatments work, and why it is absolutely essential to play an active role in your teen's recovery--even though parents have often been told to take a back seat. Learn how to monitor your teen's eating and exercise, manage mealtimes, end weight-related power struggles, and partner successfully with health care providers. When families work together to get the most out of treatment and prevent relapse, eating disorders can be beat. This book is your essential roadmap. Featuring the latest research, resources, and diagnostic information, the second edition has been expanded to cover binge-eating disorder.
Help for Worried Kids
by Cynthia LastIf your son begs to stay home from school to avoid speaking in front of the class, should you be worried? If your daughter insists on crossing the street whenever she sees a dog, what should you do? A simple evaluation devised by renowned psychologist Dr. Cynthia G. Last can help you determine if you have reason to be concerned. If so, you can use Dr. Last's checklists and examples to figure out the type and severity of your child's anxiety, identify contributing factors, and tackle the problem head on. Strategies tailored for different kinds of anxiety will guide you in preventing new episodes, calming your child when a problem arises, and keeping anxieties in check as your son or daughter matures. Dr. Last delivers powerful advice and insightful information gleaned from 25 years of experience working with worried kids and their families, including coping and relaxation skills your child can use to reduce stress and worry, and tips for encouraging kids to approach--not avoid--their fears. Whether your son or daughter can't go on sleepovers, gets nervous around peers, or just plain worries about "everything," this reassuring and compassionate book will teach you how to soothe your child's immediate fears and instill lasting confidence.
Help je kind met mindfulness angst te overwinnen
by C. MccurryGebaseerd op acceptance and commitment therapy (ACT) worden in dit praktische en toegankelijke boek diverse technieken aan ouders en (professionele) opvoeders geleerd. Deze technieken worden gebruikt door kinderpsychologen om kinderen vanaf vier jaar te helpen om angstige gevoelens los te laten en zich in plaats daarvan te richten op vriendschappen, nieuwe leerervaringen op school en plezier maken.
Help your Child or Teen Get Back On Track: What Parents and Professionals Can Do for Childhood Emotional and Behavioral Problems
by Kenneth TalanHelp Your Child or Teen Get Back on Track offers specific self-help interventions and a wide-ranging, practical discussion of the types of professional help available for a child or adolescent with emotional and behavioral problems. The book covers topics that would be discussed during a consultation with a child psychiatrist. The first section offers practical guidance and ideas to help parents understand their child's problems and learn to distinguish between normal disruption and that which warrants professional treatment. The second section of the book includes useful information for those parents who are considering, seeking, or already involved with professional help for their child. Essential reading for parents who are worried about a child or adolescent with emotional and behavioral problems, this book is also a useful resource for social workers, psychologists, school counselors, pediatricians, and adult psychiatrists.
Help! Het ziekenhuis verdwijnt: Een nieuwe kijk op de medisch-specialistische zorg van de toekomst
by F.H. HeyningMoet een ziekenhuis perse een gebouw zijn? Kunnen we moderne digitale technieken niet nog veel meer inzetten voor het allerbelangrijkste: onze gezondheid? Wat als we goede en toegankelijke gezondheidszorg breder interpreteren en daar ook goede voeding en een gezonde leefomgeving bij betrekken?Vanuit haar persoonlijke ervaring als internist-hematoloog en als bestuurder in de ziekenhuiswereld beschrijft dr. Fenna Heyning hoe het ziekenhuis zich heeft ontwikkeld van een gasthuis waar langdurig patienten verpleegd worden tot een modern technisch bolwerk, tegenwoordig meestal een groot gebouw met veel glas en staal. Maar gek genoeg zijn er nog veel wachtkamers in de ziekenhuizen, moeten patienten met toch al een zwakke conditie regelmatig van ver naar het ziekenhuis reizen en worden digitale technieken nog (te) weinig gebruikt. Dat kan dat dus beter. In dit boek leest u prachtige voorbeelden van hoe het ziekenhuis van de toekomst eruit kan zien, een ziekenhuis waar zorg zoveel mogelijk thuis wordt gegeven, met goede warme menselijke zorg voor iedereen die dat nodig heeft, dankzij de inzet van creativiteit, durf en slimme techniek.
Helping Abused and Traumatized Children
by Eliana GilPresenting an integrative model for treating traumatized children, this book combines play, art, and other expressive therapies with ideas and strategies drawn from cognitive-behavioral and family therapy. Eliana Gil demonstrates how to tailor treatment to the needs of each child by using both directive and nondirective approaches. Throughout, practical clinical examples illustrate ways to target trauma-related symptomatology while also helping children process painful feelings and memories that are difficult to verbalize. The book concludes with four in-depth cases that bring to life the unique situation of each child and family, the decision making process of the therapist, and the applications of developmentally informed, creative, and flexible interventions.
Helping Bereaved Children, Third Edition
by Nancy WebbThis acclaimed work presents a range of counseling and therapy approaches for children who have experienced loss. Practitioners and students are given practical strategies for helping preschoolers through adolescents cope with different forms of bereavement, including death in the family, school, or community. Grounded in the latest research on child therapy, bereavement, trauma, and child development, the volume clearly explains the principles that guide interventions. Featuring a wealth of new content, the third edition retains the case-based format and rich descriptions of the helping process that have made the book so popular as a practitioner guide and text. New to This Edition Significantly revised and updated to reflect new information and approaches; 9 new topics covered. Covers additional types of loss war-related death in the family, deaths connected to natural disasters, and the loss of a pet. Additional therapy modalities cognitive-behavioral therapy and play therapy; conjoint caregiver child treatment; and bereavement groups and camps. Addresses how to help parents and teachers meet bereaved children's needs. Includes 11 reproducible assessment tools and handouts that can also be downloaded and printed from Guilford's website.
Helping Children and Young People Who Experience Trauma: Children of Despair, Children of Hope
by Panos VostanisThis groundbreaking new book brings together policy, evidence, practice, service development and children's narrative to provide a far-reaching overview of this vulnerable and traumatised group. It combines powerfully written, moving scenarios and draws on evidence-based research to fully illustrate concepts and present practical ideas for change t
Helping Children and Young People who Self-harm: An Introduction to Self-harming and Suicidal Behaviours for Health Professionals
by Tim McDougall Marie Armstrong Gemma TrainorEvery year thousands of children and young people attend emergency departments with problems resulting from self-harm. More still come to the attention of CAMHS teams, school nurses and other community-based services. Helping Children and Young People who Self-harm provides clear and practical guidance for health professionals and other members of the children’s workforce who are confronted by this complex and difficult area. Providing accessible evidence-based advice, this textbook looks at: what we mean by self-harm and its prevalence the legal background what works for young people who self-harm what children and young people think about self-harm assessment and interventions for self-harm prevention of self-harm service provision and care pathways. Essential for all those working with children and young people, this textbook contains a glossary of terms, practical strategies and case studies.
Helping Couples Get Past the Affair
by Donald Baucom Douglas SnyderFrom leading marital therapists and researchers, this unique book presents a three-stage therapy approach for clinicians working with couples struggling in the aftermath of infidelity. The book provides empirically grounded strategies for helping clients overcome the initial shock, understand what happened and why, think clearly about their best interests before they act, and move on emotionally, whether or not they ultimately reconcile. The volume is loaded with vivid clinical examples and carefully designed exercises for use both during sessions and at home.