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Infektionskrankheiten in der Pädiatrie – 50 Fallstudien
by Cihan Papan Johannes HübnerVon Patientengeschichten lernen: Dieses Buch präsentiert spannende Kasuistiken aus der pädiatrischen Infektiologie, wie sie sich in jeder Kinder- und Jugendarztpraxis oder in der Notfallambulanz einer Kinderklinik ereignen könnten. Die Breite an Symptomen und resultierenden Diagnosen macht das Fallbuch besonders abwechslungsreich. Das klare Aufbauschema ermöglicht, sich die Fälle zu erarbeiten, beginnend mit dem führenden Symptom. Anamnese, Untersuchungsbefund, Laborwerte und Bildgebung umreißen das klinische Bild. Fragen zum Mitdenken fordern zu differenzialdiagnostischen Überlegungen heraus. Zum Schluss verraten die Autorinnen und Autoren die Diagnose und ziehen ein Fazit, in dem das Krankheitsbild noch einmal kompakt aufgearbeitet wird.
Infektionskrankheiten: Geschichte, Medizin, Wissenschaft, Wirtschaft, Politik und ihre Wechselwirkungen
by Heiko HerwaldAuch wenn die Medizin in den letzten Jahrzehnten enorme Fortschritte erzielt hat und gegen viele Krankheiten neue und effiziente Behandlungsmethoden entwickelt wurden, stellen schwere Infektionskrankheiten heute Ärzte vor ein fast unlösbares Problem.Glaubte man noch Mitte des 20. Jahrhunderts, dass Antibiotika ein Wundermittel seien, mit denen man das Problem von bakteriellen Infektionen in den Griff bekommen könne, so weiß man jetzt, dass sich dieses Wunschdenken als falsch erwiesen hat. Mit der rasanten Ausbreitung von antibiotikaresistenten Bakterien, müssen Forscher und Ärzte nach Alternativen suchen, um den Ausbruch von neuen Seuchen zu verhindern. Die Pestausbrüche im Mittelalter, die zum Tode von vielen Millionen Menschen geführt haben, weisen auf die Dringlichkeit einer erfolgreichen Bekämpfung von Infektionskrankheiten hin. Die Entwicklung von neuen Behandlungsmethoden ist kostenaufwendig und bedarf auch politischer Maßnahmen. Aufgrund marktstrategischer und gesundheitspolitischer Überlegungen hat die Pharmaindustrie jedoch nur ein geringes Interesse, ihre Forschungs- und Entwicklungsaktivitäten in diesem Sektor zu intensivieren. Dies und der falsche Einsatz von Antibiotika, wie z.B. in der Massentierhaltung, haben zur Folge, dass Infektionskrankheiten immer häufiger auftreten, die mit Antibiotika nicht mehr behandelt werden können. Ziel dieses Buches ist es, auf die Problematik aufmerksam zu machen und neue Ansätze aufzuzeigen, mit denen man in Zukunft bakterielle Infektionskrankheiten erfolgreich bekämpfen kann.
Inference Principles for Biostatisticians (Chapman & Hall/CRC Biostatistics Series)
by Ian C. MarschnerDesigned for students training to become biostatisticians as well as practicing biostatisticians, Inference Principles for Biostatisticians presents the theoretical and conceptual foundations of biostatistics. It covers the theoretical underpinnings essential to understanding subsequent core methodologies in the field.Drawing on his extensive exper
Inference for Diffusion Processes
by Christiane FuchsDiffusion processes are a promising instrument for realistically modelling the time-continuous evolution of phenomena not only in the natural sciences but also in finance and economics. Their mathematical theory, however, is challenging, and hence diffusion modelling is often carried out incorrectly, and the according statistical inference is considered almost exclusively by theoreticians. This book explains both topics in an illustrative way which also addresses practitioners. It provides a complete overview of the current state of research and presents important, novel insights. The theory is demonstrated using real data applications.
Inference on the Hurst Parameter and the Variance of Diffusions Driven by Fractional Brownian Motion
by Corinne Berzin Alain Latour José R. LeónThis book is devoted to a number of stochastic models that display scale invariance. It primarily focuses on three issues: probabilistic properties, statistical estimation and simulation of the processes considered. It will be of interest to probability specialists, who will find here an uncomplicated presentation of statistics tools and to those statisticians who wants to tackle the most recent theories in probability in order to develop Central Limit Theorems in this context; both groups will also benefit from the section on simulation. Algorithms are described in great detail, with a focus on procedures that is not usually found in mathematical treatises. The models studied are fractional Brownian motions and processes that derive from them through stochastic differential equations. Concerning the proofs of the limit theorems, the "Fourth Moment Theorem" is systematically used, as it produces rapid and helpful proofs that can serve as models for the future. Readers will also find elegant and new proofs for almost sure convergence. The use of diffusion models driven by fractional noise has been popular for more than two decades now. This popularity is due both to the mathematics itself and to its fields of application. With regard to the latter, fractional models are useful for modeling real-life events such as value assets in financial markets, chaos in quantum physics, river flows through time, irregular images, weather events and contaminant diffusio n problems.
Inferenzstatistik verstehen: Von A wie Signifikanztest bis Z wie Konfidenzintervall (Springer-lehrbuch Ser.)
by Markus Janczyk Roland PfisterWas bedeutet eigentlich dieser p-Wert? Und was ist ein signifikantes Ergebnis? Dieses Buch bietet eine kompakte und verständnisorientierte Einführung in die Inferenzstatistik und beantwortet Fragen wie diese. Ein Schwerpunkt ist dabei die Logik, die der Inferenzstatistik und dem Testen von Hypothesen zugrunde liegt: Die Leserin und der Leser lernen die am häufigsten verwendeten Verfahren (t-Test, Varianzanalyse mit und ohne Messwiederholung, Korrelation/Regression) sowie die Tücken der Datenauswertung kennen und entwickeln das nötige Verständnis, um Ergebnisse korrekt interpretieren zu können. Die einzelnen Kapitel werden durch konkrete Auswertungsbeispiele aus dem Forschungsalltag ergänzt – inklusive exemplarischer Umsetzung mit den Programmen SPSS und R. Neben den klassischen Methoden sind auch Querverweise auf aktuelle Entwicklungen der psychologischen Methodenforschung enthalten. Die 3. Auflage bietet inhaltliche Überarbeitungen und Ergänzungen, etwa zur Bayes-Statistik.
Inferiority Feelings: In the Individual and the Group (International Library Of Psychology Ser.)
by Oliver BrachfeldIncluding volumes originally published between 1910 and 1957, the Abnormal and Clinical Psychology set of the International Library of Psychology clearly shows the evolution of approaches to, and definitions of, conditions such as nervous anxiety, neuroses, hysteria, delinquency, insanity and mental illness, It provides a compelling insight into how attitudes to such states have changed during this century. Other subjects covered include psychotherapy with children, personality, abnormal psychology, the relationship between brain and personality and psychotic art.
Inferno: A Doctor's Ebola Story
by Steven Hatch"Hatch packs a wealth of knowledge into the book...poignant." -Associated PressDr. Steven Hatch, an infectious disease specialist, first came to Liberia in November 2013 to work at a hospital in Monrovia. Six months later, several of the physicians he had served with were dead or unable to work, and Ebola had become a world health emergency. Inferno is his account of the epidemic that nearly consumed a nation, as well as its deeper origins.Hatch returned with the aid organization International Medical Corps to help establish an Ebola Treatment Unit. Alongside a devoted staff of expats and Liberians in a hastily constructed facility nestled into the jungle, Hatch witnessed the unit's physicians, nurses, other caregivers, and patients selflessly helping others, preserving hope in the face of fear, and maintaining dignity across the divide of health and illness. And, over repeated visits during the course of the outbreak, Hatch came to understand the Ebola catastrophe not only as a contagious virus but as a product of Liberia's violent history and America's role in it.Powerful and clear-eyed, Inferno not only explores a deadly virus and an afflicted country, but also reveals how the Ebola outbreak stoked nativist anxieties that were exploited for political gain in the United States and around the world. In telling one doctor's story, Inferno demonstrates how generations of inequality left Liberia vulnerable to crisis, and how similar circumstances might fuel another plague elsewhere. By understanding and alleviating those circumstances, Hatch writes, we may help smother the fire next time.
Inferno: A Memoir of Motherhood and Madness
by Catherine ChoA New York Times Book Review Editors’ Choice "Inferno is a disturbing and masterfully told memoir, but it’s also an important one that pushes back against powerful taboos. . ." --The New York Times Book Review "Explosive" --Good Morning America"Sublime" --Bookpage (starred review) When Catherine Cho and her husband set off from London to introduce their newborn son to family scattered across the United States, she could not have imagined what lay in store. Before the trip’s end, she develops psychosis, a complete break from reality, which causes her to lose all sense of time and place, including what is real and not real. In desperation, her husband admits her to a nearby psychiatric hospital, where she begins the hard work of rebuilding her identity. In this unwaveringly honest, insightful, and often shocking memoir Catherine reconstructs her sense of self, starting with her childhood as the daughter of Korean immigrants, moving through a traumatic past relationship, and on to the early years of her courtship with and marriage to her husband, James. She masterfully interweaves these parts of her past with a vivid, immediate recounting of the days she spent in the ward.The result is a powerful exploration of psychosis and motherhood, at once intensely personal, yet holding within it a universal experience – of how we love, live and understand ourselves in relation to each other.
Infertility
by Emre SeliHelp your patients through the maze of infertility treatmentsInfertility is suffered by around 1 in 7 couples and can be a source of confusion for both partners, providing high stress on relationships. 25% of cases are explained through male infertility, 50% through female infertility, whilst 25% are generally unexplained. The possible causes and solutions are many and complex.Infertility, one of the first in the new Gynecology in Practice series, assists gynecologists and family practitioners to better care for their patients who have trouble conceiving. The authors provide a strong focus on effective diagnosis and management. Following a review of the factors that affect fertility, Infertility takes a practical approach to:Evaluation of fertilityManagement and treatmentComplicationsPre-implantation screeningFertility preservationGynecology in PracticeThe Gynecology in Practice series provides clinical 'in the office' or 'at the bedside' guides to effective patient care for gynecologists. The tone is practical, not academic, with authors offering guidance on what might be done and what should be avoided. The books are informed by evidence-based practice and feature:Algorithms and guidelines where they are appropriate''Tips and Tricks' boxes - hints on improving outcomes'Caution' warning boxes - hints on avoiding complications'Science Revisited' - quick reminder of the basic science principlesSummaries of key evidence and suggestions for further reading
Infertility Around the Globe: New Thinking on Childlessness, Gender, and Reproductive Technologies
by Marcia C. Inhorn Frank Van BalenThis collection of essays breaks examines the global impact of infertility as a major reproductive health issue, one that has profoundly affected the lives of countless women and men. Based on original research by seventeen internationally acclaimed social scientists, it investigates the use of reproductive technologies in non-Western countries.
Infertility Counseling
by Sharon N. Covington Linda Hammer BurnsInfertility Counseling: A Comprehensive Handbook for Clinicians, second edition, is a comprehensive, multidisciplinary textbook for all health professionals providing care for individuals facing reproductive health issues. It is the most thorough and extensive book currently available for clinicians in the field of infertility counseling, providing an exhaustive and comprehensive review of topics. It addresses both the medical and psychological aspects of infertility, reviewing assessment approaches, treatment strategies, counseling for medical conditions impacting fertility, third-party reproduction, alternative family building and post infertility counseling issues. Each chapter follows the same format: introduction, historical overview, literature review, theoretical framework, identification of clinical issues, suggestions for therapeutic interventions, and future implication. This edition also includes extensive appendixes of clinical tools useful to the clinician, including an Internet database of resources and an extensive glossary of terminology.
Infertility and Multiple Miscarriages: Diagnosis Treatment Options and How to Cope (ACOG Patient Education)
by AcogInfertility is a common problem, and it can happen even if you' ve been pregnant before. In the United States, as many as 15 in 100 couples have trouble getting pregnant. If you are trying to have a baby and have not gotten pregnant, you and your partner may need an infertility evaluation. Exams and tests can be done to try to find the reason why you and your partner have not gotten pregnant. In this booklet, you' ll learn how pregnancy works, some possible causes of infertility and multiple miscarriages, what tests you might need, and what treatments are available.
Infertility in Early Modern England
by Daphna Oren-MagidorThis book explores the experiences of people who struggled with fertility problems in sixteenth and seventeenth-century England. Motherhood was central to early modern women's identity and was even seen as their path to salvation. To a lesser extent, fatherhood played an important role in constructing proper masculinity. When childbearing failed this was seen not only as a medical problem but as a personal emotional crisis. Infertility in Early Modern England highlights the experiences of early modern infertile couples: their desire for children, the social stigmas they faced, and the ways that social structures and religious beliefs gave meaning to infertility. It also describes the methods of treating fertility problems, from home-remedies to water cures. Offering a multi-faceted view, the book demonstrates the centrality of religion to every aspect of early modern infertility, from understanding to treatment. It also highlights the ways in which infertility unsettled the social order by placing into question the gendered categories of femininity and masculinity.
Infertility in Practice (Reproductive Medicine and Assisted Reproductive Techniques Series)
by Adam H BalenThis text has been written as a practical guide, based on the author’s experience over the last 40 years of daily clinical practice and aiming to place the modern approach to the management of infertility in the context of sound theory and evidence-based therapy. It provides the reader with a comprehensive classification of the causes of infertility, their investigation, and their management. This new edition covers many advances in the understanding and management of infertility and other updates to practice--for example, a greater understanding of the pathophysiology of ovarian aging and ovarian reserve testing; the classification of disorders of ovulation and management of polycystic ovary syndrome; the refinement of regimens for superovulation, improved embryo culture systems, and the use of artificial intelligence for the selection of embryos; assessments for endometrial receptivity and management of recurrent implantation failure; pre-implantation genetic testing (PGT) as a therapeutic tool opening up the possibility for aneuploidy screening; as well as the latest thoughts on nutritional health, periconception care, and the exciting new world of the microbiome.
Infertility in Women with Polycystic Ovary Syndrome
by Stefano PalombaThis book presents up-to-date knowledge on infertility in the context of polycystic ovary syndrome (PCOS) and provides clear evidence-based guidance on its treatment. The book opens by discussing anovulation, oocyte quality, and the endometrium in women with PCOS, infertility and subfertility cofactors, and the impact of PCOS phenotypes on fertility. All aspects of management are then thoroughly addressed. The available medical treatments for PCOS-related infertility - including antiestrogens, aromatase inhibitors, insulin-sensitizing drugs, and gonadotropins - are reviewed, and other potential therapeutic approaches, such as acupuncture and laparoscopic ovarian drilling, are assessed. Careful attention is also devoted to the role of lifestyle interventions. The use of controlled ovarian stimulation in infertile PCOS patients undergoing intrauterine insemination or in vitro fertilization is examined in detail, as are the benefits of in vitro maturation of oocytes. This book will be of value to all who are involved in the care of women with PCOS and related infertility issues.
Infertility in the Male
by Larry I. Lipshultz Stuart S. Howards Craig S. NiederbergerThis complete reference book covers all aspects of male reproductive biology and applied clinical diagnosis and therapy and includes a lab manual. Chapters are authored by physicians in the fields of urology, gynecology and endocrinology providing in-depth discussions on the latest developments in male infertility. All causes of male infertility are addressed.
Infertility in the Male
by Larry I. Lipshultz Stuart S. Howards Craig S. Niederberger Dolores J. LambThis gold standard text has kept its readers abreast of rapid advancements in reproductive medicine and surgery since 1983. Continuing this tradition, this fifth edition has been fully updated and revised to provide clear, didactic advice on best practice for a variety of clinical situations faced by practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice who see men with suboptimal fertility and reproductive problems. Completely restructured to include pedagogical features such as easily accessible key concepts that cement understanding and real-world use. Covering everything from foundations of anatomy and embryology, through clinical evaluation, diagnostic approaches, treatment and fertility care in context within the healthcare system and society, thrilling advances and future directions are also included. This new edition is an essential reference for all who are working in this young and rapidly evolving field.
Infertility: Tracing the History of a Transformative Term (RSA Series in Transdisciplinary Rhetoric #3)
by Robin E. JensenThis book explores the arguments, appeals, and narratives that have defined the meaning of infertility in the modern history of the United States and Europe. Throughout the last century, the inability of women to conceive children has been explained by discrepant views: that women are individually culpable for their own reproductive health problems, or that they require the intervention of medical experts to correct abnormalities. Using doctor-patient correspondence, oral histories, and contemporaneous popular and scientific news coverage, Robin Jensen parses the often thin rhetorical divide between moralization and medicalization, revealing how dominating explanations for infertility have emerged from seemingly competing narratives. Her longitudinal account illustrates the ways in which old arguments and appeals do not disappear in the light of new information, but instead reemerge at subsequent, often seemingly disconnected moments to combine and contend with new assertions.Tracing the transformation of language surrounding infertility from “barrenness” to “(in)fertility,” this rhetorical analysis both explicates how language was and is used to establish the concept of infertility and shows the implications these rhetorical constructions continue to have for individuals and the societies in which they live.
Infertility: Women Speak Out About Their Experiences of Reproductive Medicine (Routledge Library Editions: Women in Society)
by Renate D. KleinOriginally published in 1989, Infertility looks at how fertility treatments fail women. At the time there was disturbing evidence of medical malpractice and invasive technologies which violated women’s bodies and took a heavy toll on their lives.Here for the first time, women – from all over the world – tell their own stories about: the pain and stigma of infertility; never-ending cycles of drugs and hormone injections; the trauma of the ‘test-tube baby’ method (IVF); their unmet hopes when technology fails – yet again; the damage caused by experimental medicine and surgery; how they have been exploited as so-called ‘surrogate’ mothers.These shocking stories shattered the myths of benevolent doctors working in the interests of women.The women who speak out in this book offer support and suggest alternative strategies for other people with fertility problems. Their experiences show that we urgently need to resist the false promise of reproductive technologies if all women are not to become test-sites for medical experimentation and scientific ambition. Still often discussed today it is considered a classic in the field.
Infiltrating Healthcare: How Marketing Works Underground to Influence Nurses
by Quinn GrundyHow sales representatives from Big Pharma and other healthcare companies circumvent public and regulatory scrutiny by forging relationships with nurses.Awarded second place in the 2019 AJN Book of the Year Award in the Professional Issues Category by the American Journal of NursingIt was once common for pharmaceutical companies and medical device makers to treat doctors to lavish vacations or give them new cars; companies would do virtually anything to buy influence so that their medications or devices would be used in a doctor’s office or hospital. But with growing public scrutiny of kickbacks to doctors, the huge giveaways have disappeared. In Infiltrating Healthcare, Quinn Grundy shows that sales representatives are working instead behind the scenes. It is to nurses that these companies now market. Nurses, Grundy argues, are the perfect target for sales reps: their work is largely invisible and frequently undervalued, yet they wield a great deal of influence over treatment and purchasing decisions. Furthermore, there are no legal restrictions on marketing to most nurses. Grundy describes how, under the guise of education or product support, and through gifts and free samples, sales representatives influence nurses in the course of day-to-day clinical practice. Grundy argues that the very presence of sales reps in operating rooms, purchasing committee meetings, and patient care units blurs the boundaries between patient care and medical sales. Helpfully, she also describes ways that nurses can be aware of (and resistant to) their influence. Infiltrating Healthcare is a call to action to protect the clinical spaces where we are at our most vulnerable—and the decisions that take place there—from the pursuit of profit at any cost. This is a timely book that shines a light on a practice that often goes unseen, and which has tangible implications for healthcare policy and practice.
Infinite Dimensions: Stories
by Jessica TreadwayTwelve short stories delving into the minds of characters struggling as they attempt to build their lives on shaky ground.A female bank executive, who thinks she&’s placed her struggles with mental illness behind her, must make a tough decision when her former hospital roommate shows up for a job interview. A college student struggling with his philosophy assignment asks a relative for help only to be troubled by the results. A recovering alcoholic author teeters on the edge of self-sabotage as she travels to a dinner meeting with an influential editor. A woman longs to have a brain tumor so that she might get some attention . . .These are just a few of the characters inhabiting Infinite Dimensions, from thewinner of the Flannery O&’Connor Award for Short Fiction for Please Come Back to Me. In this collection, Jessica Treadway links her stories with vulnerable characters in similar settings, featuring themes of fidelity, betrayal, and self-delusion. And throughout all of it, she reveals her stunning grasp of human psychology in all its complex forms.Praise for Infinite Dimensions&“Jessica Treadway&’s intense and moving stories are connected by an intriguing thread, yet each one stands alone as a gem of intuition and empathy. This is a stellar collection.&” —Hilma Wolitzer, author of Today a Woman Went Mad in the Supermarket&“What an exquisite gift. . . . A masterclass in the story form, Treadway&’s riveting collection awakens us to the marvel of our ordinary lives, even as it demonstrates how little it takes to shatter them. . . . This book is simply astonishing.&” —E. J. Levy, author of The Cape Doctor and Love, in Theory&“Treadway&’s dynamic collection . . . intuitively explores the vulnerabilities of her characters. . . . These stories are powerful and believable.&” —Publishers Weekly
Inflamed: Deep Medicine and the Anatomy of Injustice
by Raj Patel Rupa MaryaRaj Patel, the New York Times bestselling author of The Value of Nothing, teams up with physician, activist, and co-founder of the Do No Harm Coalition Rupa Marya to reveal the links between health and structural injustices--and to offer a new deep medicine that can heal our bodies and our world.The Covid pandemic and the shocking racial disparities in its impact. The surge in inflammatory illnesses such as gastrointestinal disorders and asthma. Mass uprisings around the world in response to systemic racism and violence. Rising numbers of climate refugees. Our bodies, societies, and planet are inflamed.Boldly original, Inflamed takes us on a medical tour through the human body—our digestive, endocrine, circulatory, respiratory, reproductive, immune, and nervous systems. Unlike a traditional anatomy book, this groundbreaking work illuminates the hidden relationships between our biological systems and the profound injustices of our political and economic systems. Inflammation is connected to the food we eat, the air we breathe, and the diversity of the microbes living inside us, which regulate everything from our brain’s development to our immune system’s functioning. It’s connected to the number of traumatic events we experienced as children and to the traumas endured by our ancestors. It’s connected not only to access to health care but to the very models of health that physicians practice.Raj Patel, the renowned political economist and New York Times bestselling author of The Value of Nothing, teams up with the physician Rupa Marya to offer a radical new cure: the deep medicine of decolonization. Decolonizing heals what has been divided, reestablishing our relationships with the Earth and one another. Combining the latest scientific research and scholarship on globalization with the stories of Marya’s work with patients in marginalized communities, activist passion, and the wisdom of Indigenous groups, Inflamed points the way toward a deep medicine that has the potential to heal not only our bodies, but the world.
Inflammasome Signaling and Bacterial Infections
by Steffen BackertThis volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.
Inflammation
by Björn E. Clausen Jon D. LamanThis volume presents a broad selection of cutting-edge methods and tools that will enable the reader to investigate the multi-faceted manifestations of inflammation. Inflammation: Methods and Protocols is divided into four sections: the first three sections describe protocols investigating immune-mediated inflammatory disease models affecting barrier organs to the environment; the skin, the lung, and the intestinal and oral mucosa. The fourth section illustrates inflammatory disease models of the brain, joints, and vasculature. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and practical, Inflammation: Methods and Protocols aims to inspire the experienced investigator and the young experimenter alike to disentangle the fascinating process of inflammation.