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Laboratory Design Handbook
by E. Crawley CooperLaboratory Design Handbook describes the process, motivation, constraints, challenges, opportunities, and specific design data related to the creation of a modern research laboratory. The information presented is based on a large pool of experience in the development of new and renovated laboratory buildings for universities, teaching hospitals, ph
Laboratory Guide to Enzymology
by Geoffrey A. Holdgate Antonia Turberville Alice LanneLABORATORY GUIDE TO ENZYMOLOGY An accessible guide to understanding the foundations of enzymology at its application in drug discovery Enzymes are highly specialized proteins necessary for performing specific biochemical reactions essential for life in all organisms. In disease, the functioning of these enzymes can become altered and, therefore, enzymes represent a large class of key targets for drug discovery. In order to successfully target dysfunctional enzymes pharmaceutically, the unique mechanism of each enzyme must be understood through thorough and in-depth kinetic analysis. The topic of enzymology can appear challenging due its interdisciplinary nature combining concepts from biology, chemistry, and mathematics. Laboratory Guide to Enzymology brings together the theory of enzymology and associated lab-based work to offer a practical, accessible guide encompassing all three scientific disciplines. Beginning with a brief introduction to proteins and enzymes, the book slowly immerses the reader into the foundations of enzymology and how it can be used in drug discovery using modern methods of experimentation. The result is a detailed but highly readable volume detailing the basis of drug discovery research. Laboratory Guide to Enzymology readers will also find: Descriptions of key concepts in enzymology Examples of drugs targeting different enzymes via different mechanisms Detailed discussion about many areas of enzymology such as binding and steady-state kinetics, assay development, and enzyme inhibition and activation Laboratory Guide to Enzymology is ideal for all pharmaceutical and biomedical researchers working in enzymology and assay development, as well as advanced students in the biochemical or biomedical sciences looking to develop a working knowledge of this field of research.
Laboratory Guide to the Methods in Biochemical Genetics
by Nenad Blau Frédéric M. VazNow in its 2nd edition, this manual describes laboratory methodology for the diagnosis of inherited metabolic diseases. The book describes a spectrum of tests, from simple screening methods via classical methods that are operational in most (if not all) biochemical laboratories, to analytical methods that depend on technologies that very few are currently employing in their labs, but are certainly the functional techniques in a biochemical laboratory in this post-genomics era. Each chapter is sufficiently detailed to be self-contained, thus enabling laboratory specialists to adopt the method in their own laboratory and obviating the need for additional methods or references. The second updated edition of the book is unique in that it is the first of its kind to be published in the last 13 years, and individual chapters have been developed by experts in the field citing both established and cutting-edge (omics) technology. Thus, it is an indispensable resource for researchers and clinicians working on the field of inherited metabolic diseases and those interested in laboratory diagnoses.
Laboratory Hematology Practice
by Bruce Davis Kandice Kottke-MarchantExpertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.
Laboratory Hemostasis
by Sterling T. Bennett Christopher M. Lehman George M. RodgersCoagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anticoagulant monitoring and management. This handbook provides practical information and guidance on topics relevant to directing a coagulation laboratory, filling a void in the literature. Since the first edition, all chapters have been updated and an entirely new chapter is included on pharmacogenomics and pharmacogenetics. The book will aid pathologists, clinical laboratory scientists and other physicians serving as laboratory directors to understand and carry out their responsibilities. It will also assist residents and fellows in learning the basics of coagulation testing and serve as a useful day-to-day reference for coagulation laboratory supervisors, technologists, and technicians. Finally, clinicians may find aspects of the book helpful in understanding the role of the coagulation laboratory in patient evaluation and monitoring.
Laboratory Imaging & Photography: Best Practices for Photomicrography & More (Applications in Scientific Photography)
by Michael PeresLaboratory Imaging and Photography: Best Practices for Photomicrography and More is the definitive guide to the production of scientific images. Inside, the reader will find an overview of the theory and practice of laboratory photography, along with useful approaches to choosing equipment, handling samples, and working with microscopic subjects. Drawing from over 150 years of combined experience in the field, the authors outline methods of properly capturing, processing and archiving the images that are essential to scientific research. Also included are chapters on applied close-up photography, artificial light photography and the optics used in today’s laboratory environment, with detailed entries on light, confocal and scanning electron microscopy. A lab manual for the digital era, this peerless reference book explains how to record visual data accurately in an industry where a photograph can serve to establish a scientific fact. Key features include: Over 200 full-color photographs and illustrations A condensed history of scientific photography Tips on using the Adobe Creative Suite for scientific applications A cheat sheet of best practices Methods used in computational photography
Laboratory Investigations of Thrombophilia: Clinical and Practical Aspects
by Akbar Dorgalaleh Anvarjon SamadovThis comprehensive book offers an in-depth overview of laboratory diagnoses for both inherited and acquired thrombophilias, illuminating the complex interplay between genetic and environmental factors that contribute to venous thromboembolism. Beginning with foundational concepts in thrombophilia testing, the book systematically covers the diagnosis of key anticoagulant deficiencies, including protein C, protein S, protein Z, antithrombin, and plasminogen, as well as the critical evaluation of prothrombin G20210A and factor V Leiden mutations and other factors involved in thrombosis. It also addresses acquired thrombophilia, highlighting the significant impact of factors such as hyperhomocysteinemia and the influence of medications, lifestyle choices, and underlying health conditions on thrombosis risk. Each chapter clarifies the principles behind various laboratory assays, detailing the preanalytical variables that can affect results and guiding the interpretation of findings. Real-world challenges in thrombophilia testing such as during pregnancy, the use of oral contraceptives, and monitoring anticoagulation therapy are specifically examined. Written in a clear yet comprehensive style, this book is aimed at thrombosis specialists, hematologists, laboratory scientists, and students. It provides extensive knowledge, practical guidance, and evidence-based protocols for thrombophilia testing, ensuring accurate diagnosis and effective management of this life-threatening disorder.
Laboratory Manual For Anatomy And Physiology Featuring Martini Art, Main Version
by Michael WoodThis laboratory manual is designed to serve the lab course that accompanies the two-semester anatomy and physiology lecture course. It provides students with comprehensive coverage of anatomy and physiology, beautiful full-color art and photographs, and an intuitive pedagogical framework. The primary goals of this manual are to provide students with hands-on experiences that reinforce the information they learn in the lecture course and to help them understand three-dimensional relationships, visualize complex structures, and comprehend intricate physiological processes. The manual is written to correspond to all current two-semester anatomy and physiology textbooks, although those students and instructors using Fundamentals of Anatomy & Physiology, Tenth Edition, by Frederic H. Martini, Judi L. Nath, and Edwin F. Bartholomew will recognize here some of the superb art from that text by William Ober and Claire Garrison, Martini's renowned biomedical illustrators. This sixth edition manual is available in three separate versions. The Main Version covers the full two-semester A&P curriculum, including dissections of the cow eye and of the sheep heart, brain, and kidney. The Cat Version includes all of the same material plus an additional section of nine cat dissection exercises encompassing the major body systems. The Pig Version, similarly, includes all of the material from the Main Version with a separate section of nine fetal pig dissection exercises. The Cat and Pig Versions make the manual more useful to instructors whose students perform animal dissections in the lab. The outstanding dissections and accompanying photographs are by Shawn Miller and Mark Neilsen and I thank each of them for their expertise.
Laboratory Manual For Clinical Kinesiology And Anatomy (Fourth Edition)
by Lynn S. Lippert Mary Alice Duesterhaus MinorDivided into three sections, it will help you to prepare for lab, guide you through lab activities, and serve as an after-lab review that ensures you build a solid knowledge base of kinesiology.
Laboratory Manual for Biotechnology and Laboratory Science: The Basics, Revised Edition
by Lisa A. Seidman Mary Ellen Kraus Diana Lietzke Brandner Jeanette MoweryProvides the basic laboratory skills and knowledge to pursue a career in biotechnology. Written by four biotechnology instructors with over 20 years of teaching experience, it incorporates instruction, exercises, and laboratory activities that the authors have been using and perfecting for years. These exercises and activities help students understand the fundamentals of working in a biotechnology laboratory. Building skills through an organized and systematic presentation of materials, procedures, and tasks, the manual explores overarching themes that relate to all biotechnology workplaces including forensic, clinical, quality control, environmental, and other testing laboratories.Features:• Provides clear instructions and step-by-step exercises to make learning the material easier for students. There are Lab Notes for Instructors in the Support Material (see tab below).• Emphasizes fundamental laboratory skills that prepare students for the industry.• Builds students’ skills through an organized and systematic presentation of materials, procedures, and tasks.• Updates reflect recent innovations and regulatory requirements to ensure students stay up to date.• Supplies skills suitable for careers in forensic, clinical, quality control, environmental, and other testing laboratories.
Laboratory Manual for Classification and Morphology of Rumen Ciliate Protozoa
by B.A. DehorityThe only rumen protozoa lab guide featuring line drawings created by a leading scientist in the fieldLaboratory Manual for Classification and Morphology of Rumen Ciliate Protozoa is a unique lab guide for learning how to count and identify rumen protozoa. In this guide, Professor Dehority has created line drawings of rumen protozoa that emphasize morphological features and size measurements. The book also provides keys for identifying genera and species, and it contains classifications and descriptions of the different orders and families of rumen ciliate protozoa. Procedures for counting rumen protozoa and identifying individual species are included as well.Laboratory Manual for Classification and Morphology of Rumen Ciliate Protozoa will be an excellent identification guide for protozoologists, microbiologists, dairy scientists, and any researcher or student working with rumen protozoa.
Laboratory Manual for Clinical Anatomy and Physiology for Veterinary Technicians
by Joanna M. Bassert Thomas ColvilleLearn to apply your A&P learning in the lab setting with Colville and Bassert’s Lab Manual for Clinical Anatomy and Physiology for Veterinary Technicians, 3rd Edition. This practical laboratory resource features a variety of activities, such as crossword puzzles, , terminology exercises, illustration identification and labeling, case presentations, and more to help reinforce your understanding of veterinary anatomy and physiology. The lab manual also features vivid illustrations, lists of terms and structures to be identified, and step-by-step dissection guides to walk you through the dissection process. <P><P> Clinically-oriented learning exercises help readers become familiar with the language of anatomy and physiology as you identify structures and learn concepts. Clear step-by-step dissection instructions for complex organs such as the heart familiarize readers with the dissection process in a very visual, easy-to-understand format. Learning objectives, the clinical significance of the content, and lists of terms and structures to be identified appear at the beginning of each chapter. Comprehensive glossary appears at the end of the lab manual and provides accurate, concise. High quality, full color illustrations provides a firm understanding of the details of anatomic structure. Review activities and study exercises are included in every chapter to reinforce important information. Clinical Application boxes are threaded throughout the lab manual and demonstrate the clinical relevance of anatomic and physiologic principles. Companion Evolve site includes answers to the Test Yourself questions in the textbook and crossword puzzles. NEW! Overview at a Glance sections outline the main proficiencies of each chapter and include a list of all exercises in the chapter.
Laboratory Manual for Clinical Anatomy and Physiology for Veterinary Technicians
by Joanna M. Bassert Thomas P. ColvilleLearn to apply your A&P learning in the lab setting with the Laboratory Manual for Clinical Anatomy and Physiology for Veterinary Technicians, 4th Edition. This practical laboratory resource features a variety of activities, such as terminology exercises, illustration identification and labelling, case presentations, and more to help reinforce your understanding of veterinary anatomy and physiology. The laboratory manual also features vivid illustrations, lists of terms and structures to be identified, and step-by-step dissection guides to walk you through the dissection process. <p><p> Clinically oriented learning exercises introduce you to the language of anatomy and physiology as you identify structures and learn concepts. <p><p>Clear, step-by-step dissection instructions for complex organs such as the heart familiarize you with the dissection process in a very visual, easy-to-understand format. <p><p>Learning objectives, the clinical significance of the content, and lists of terms and structures to be identified appear at the beginning of each chapter. <p><p>Review activities and study exercises are included in every chapter to reinforce important information. <p><p>High-quality, full-color illustrations provide a solid understanding of the details of anatomic structure.
Laboratory Manual for Mohs Micrographic Surgery: Frozen Tissue Processing
by Kishwer S. Nehal Camille McKayThis manual provides a thorough and up-to-date reference on the Mohs tissue processing technique. Mohs micrographic surgery is a distinct surgical and tissue processing technique that allows comprehensive margin control for high-risk skin cancers with the highest cure rate. Mohs micrographic surgery entails expertise in Mohs tissue frozen section processing in a fully licensed Mohs laboratory.Laboratory Manual for Mohs Micrographic Surgery Frozen Tissue Processing provides extensive practical guidance on optimal management from the leading experts in the field including perspectives from Mohs technicians, laboratory managers, Mohs surgeons and regulatory affairs. It covers the Mohs lab training curriculum for technicians and Micrographic Surgery and Dermatologic Oncology fellows and therefore is an extremely valuable resource for any healthcare professional in the Mohs micrographic surgery field.
Laboratory Manual for Seeley's Anatomy and Physiology (11th Edition)
by Eric WiseLaboratory Manual For Seeley's Anatomy And Physiology, Eleventh Edition
Laboratory Methodology in Biochemistry: Amino Acid Analysis and Protein Sequencing
by Carlo FiniProvides information on methodologies and techniques concerning the biochemical laboratory, as well as improvements or advancements made on existing methodologies. Original methodologies for the purification of biological macromolecules and methodologies for metabolic pathways and enzyme kinetics are covered. The application of biochemical and biophysical methodologies for the structural and dynamic characterization of biological macromolecules is considered. The elaboration of automated systems for biochemical research and computer programs for the management and processing of experimental data are both reviewed. Development of instruments and equipment for biochemical research is also presented.
Laboratory Models for Foodborne Infections (Food Microbiology)
by Dongyou Liu Laszlo EndrenyiResulting from ingestion of inappropriately prepared or stored foods containing pathogenic viruses, bacteria, fungi and parasites, foodborne infections have become a significant source of human morbidity and mortality worldwide in recent decades. This may be largely attributable to the remarkable popularity of convenient, ready-to-eat food products, the dramatic expansion of international food trades, and the continuing growth of immuno-suppressed population groups. Although anti-microbial treatments have played a crucial part in the control of foodborne infections in the past, the emergence and spread of anti-microbial resistance render the existing treatments ineffective. Additionally, our limited understanding of the molecular mechanisms of foodborne infections has thwarted our efforts in the development of efficacious vaccines for foodborne pathogens. Given the obvious benefits of laboratory models in foodborne disease research, a great number of experiments have been conducted toward the elucidation of host-pathogen interactions in and pathogenic mechanisms of foodborne infections. Forming part of the Food Microbiology series, Laboratory Models for Foodborne Infections presents a state-of-the-art review of laboratory models that have proven valuable in deciphering the life cycle, epidemiology, immunobiology, and other key aspects of foodborne pathogens. Written by scientists with respective expertise in foodborne pathogen research, each chapter includes a contemporary summary of a particular foodborne viral, bacterial, fungal, or parasitic infection in relation to its life cycle, epidemiology, clinical features, pathogenesis, host-pathogen interactions, and other related aspects. Besides providing a trustworthy source of information for undergraduates and postgraduates in food microbiology, Laboratory Models for Foodborne Infections offers an invaluable guide for scientists and food microbiologists with interest in exploiting laboratory models for detailed study of foodborne infections.
Laboratory Mouse Procedural Techniques: Manual and DVD
by John J. Bogdanske Scott Hubbard-Van Stelle Margaret Rankin Riley Beth SchiffmanThis combination manual and DVD provides much-needed training on the proper handling of mice used in biomedical research. The DVD includes narrated video clips that demonstrate and describe each procedural technique. The manual contains handouts with color illustrations and descriptive text for each technique, including the purpose and application
Laboratory Pathology Words and Phrases
by Sally Crenshaw PitmanBook useful for medical transcriptionists. Includes laboratory terminology, tables of bones, muscles, nerves and more.
Laboratory Procedures for Veterinary Technicians (5th edition)
by Charles M. Hendrix Margi SiroisFive American academics contribute nine chapters to an updated text for practicing veterinary technicians, veterinary assistants, and veterinary technology students. The text covers principles and procedures for laboratory diagnostics in the areas of clinical chemistry, microbiology, hematology, homeostasis, parasitology, urinalysis, immunology, and cytology. It assumes a basic understanding of the anatomy and physiology of common species. The new edition has been significantly updated with expanded information reflecting the latest developments in the veterinary clinical laboratory since publication of the 2002 edition. It includes new sections on laboratory mathematics, hematopoiesis, molecular diagnostics, and the physiologic basis of immunity; expanded information on clinical analyzers and quality assurance; and information on professional associations related to veterinary clinical pathology. Illustrated with full color and b&w photomicrographs, charts, and diagrams. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)
Laboratory Procedures for Veterinary Technicians - Elsevier on VitalSource
by Charles M. Hendrix Margi SiroisClearly presents the fundamentals of microbiology, hematology, urinalysis, immunology, parasitology, and cytology along with the laboratory procedures used to perform tests in these fields.Features the latest information on the most widely used tests, including complete blood count, urinalysis, and immunology assays.Features step-by-step procedure boxes, for quick mastery of essential skills.Extensive full-color illustrations enhance descriptions of normal and abnormal findings.New co-author Margi Sirois is a respected author and renowned speaker on laboratory procedures, particularly clinical pathology.Now in full-color with hundreds of vivid illustrations that demonstrate key concepts.New smaller size is more convenient and portable.Features expanded sections on laboratory safety and quality control, all routine CBC and coagulation tests, serum chemistry tests, electrolyte and endocrine function testing, innate and adaptive immune systems, bone marrow evaluation, and cytology sample collection and handling.New sections include the formation of blood cells, histograms produced by automated cell counters, bacterial and fungal morphology, microorganisms, molecular diagnostics, radioimmunoassay and fluorescent antibody (FA) testing, the physiology of immunity, and algorithms for the evaluation of cytology samples.Dozens of new chemistry, hematology, and microbiology boxes and tables synthesize essential information.Key Points summarize important concepts for quick review.
Laboratory Rat Procedural Techniques: Manual and DVD
by John J. Bogdanske Scott Hubbard-Van Stelle Margaret Rankin Riley Beth SchiffmanThis combination manual and downloadable resources provide much-needed training on the proper handling of rats used in biomedical research. The downloadable resources include narrated video clips that demonstrate and describe each procedural technique. The manual contains handouts with color illustrations and descriptive text for each technique, including the purpose and application of the procedure, recommended skills, and necessary supplies. It can be used as a training resource and refresher for lab animal veterinarians, veterinary technicians, animal care staff, trainers, and research investigators and staff who work with rats.
Laboratory Science with Space Data
by Martin Zell Luigi Carotenuto Jack J.W.A. van Loon Daniel BeysensFor decades experiments conducted on space stations like MIR and the ISS have been gathering data in many fields of research in the natural sciences, medicine and engineering. The EU-sponsored Ulisse Internet Portal provides metadata from space experiments of all kinds and links to the data. Complementary to the portal, this book will serve as handbook listing space experiments by type of infrastructure, area of research in the life and physical sciences, data type, what their mission was, what kind of data they have collected and how one can access this data through Ulisse for further research. The book will provide an overview of the wealth of space experiment data that can be used for research, and will inspire academics (e.g. those looking for topics for their PhD thesis) and research departments in companies for their continued development.
Laboratory Skills for Science and Medicine: An Introduction
by Susan Greenfield Maxine Lintern Vern BarnetThis work contains a Foreword by Baroness Susan Greenfield, Director, Royal Institution of Great Britain, Fullerian Professor of Physiology, Senior Research Fellow Lincoln College and Honorary Fellow, St. Hilda's College, University of Oxford. This practical, concise and up-to-date guide is ideal as a quick reference. It is easy to read, refer to and comprehend - the perfect text to have on hand in the laboratory. "Laboratory Skills for Science and Medicine" contains useful equations, overviews of various techniques, and tips to help research run smoothly. Undergraduate and postgraduate students of science, medicine and biomedical science will find this manual invaluable, as will PhD candidates and researchers returning to laboratory work. 'Becoming a good biomedical researcher, like everything else in life, doesn't just happen overnight. Exploring your knowledge and skills base, and the gaps therein allows you to develop your approach to research in a systematic and productive manner. By taking advantage of the experience bundled into this volume, you are giving yourself the advantage of both an increased factual knowledge and useful practical applications which will help you on the road to achieving your goals, whether that is a good first degree, your first publication, that first grant or a Noble prize! If you want to give yourself a flying start in your lab career, then this book is for you.' - Maxine Lintern, in the Introduction.
Laboratory Tests for the Assessment of Nutritional Status (Modern Nutrition Ser. #21)
by Howerde E. SauberlichProper nutrition is the single most important component of preventative health care. Heart disease, diabetes, and other ailments are all linked to dietary habits. Accurate nutritional assessment can be a matter of life or death. Laboratory Tests for the Assessment of Nutritional Status explores the expanded number of nutrients that can now be evaluated. The author makes a compelling case for the practice and advancement of this critical health care tool. Nutritional assessment identifies undernutrition, overnutrition, specific nutrition deficiencies, and imbalances. Diligent assessment determines the appropriate nutrition intervention and monitors its effects. This book is a total revision of the 1974 version of the same title co -authored by Sauberlich. Since then, remarkable progress has been made on the methodologies applicable to nutrition status assessment and to the expanded number of nutrients that can be evaluated, especially trace elements. The introduction of high-performance liquid chromatography, amperometric detectors, and other technologies has advanced nutritional assessment by leaps and bounds. Today, nutritionists can gauge the value of microminerals, trace elements, and ultratrace elements. Sauberlich's revision updates the reader to the latest and most important trends in nutrition. These laboratory methods for the assessment of nutritional status are vital for identifying individuals as well as populations with nutritional risks.