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Knowledge Management in the Pharmaceutical Industry: Enhancing Research, Development and Manufacturing Performance
by Elisabeth Goodman John RiddellThe Pharmaceutical Industry has been undergoing a major transformation since the heady days of 'big pharma' in the 1970s and 80s. Patent expiry, the rise of generics, and the decline of the blockbuster drug have all changed the landscape over the last 10-15 years. It's an environment where products can take 10 years or more to come to market, billions are spent on research and development, jobs are being shed in the western pharma homelands and regulators and the public are more demanding than ever. So what part is Knowledge Management playing and going to play in this vital international industry? Knowledge Management (KM) has many facets from providing comprehensive knowledge bases for workers, through the sharing of advice and problem solving, to providing an environment for innovation and change. This book, focusing on research and development, and manufacturing-based companies, explores how a range of techniques and approaches have been applied in the unique environment of the Pharmaceutical Industry, and examine how it can help the industry in the 21st century. Whilst the book is centered on the Pharmaceutical Industry, its objective will be to discuss and demonstrate how Knowledge Management can be applied in a variety of environments, and with a range of cultural issues. KM practitioners, and potential practitioners, both within and outside the Pharmaceutical Industry, will be able to gain valuable guidance and advice from both the examples of good practice and the lessons learned by the authors and contributors.
Knowledge Representation for Health Care
by David Riaño Richard Lenz Silvia Miksch Mor Peleg Manfred Reichert Annette Ten TeijeThis book constitutes the thoroughly refereedpost-workshop proceedings of two workshops held at the International Conferenceon Artificial Intelligence in Medicine, AIME 2015, held in Pavia, Italy, inJune 2015: the 7th International Workshop on Knowledge Representation forHealth Care, KR4HC 2015, and the 8th International Workshop on Process-orientedInformation Systems in Healthcare, ProHealth 2015. The 10 revised full papers were carefullyreviewed and selected from 26 submissions. The papers are organized in topicalsections on knowledge-driven health IT and simulation, clinical guideline andclinical pathway support, mobile process and decision support, and healthinformation systems and clinical data.
Knowledge Representation for Health Care
by David Riaño Silvia Miksch Annette Ten TeijeThis book constitutes the refereed proceedings of the 6th International Workshop on Knowledge Representation for Health Care, KR4HC 2014, held as part of the Vienna Summer of Logic, VSL 2014, in Vienna, Austria, in July 2014. The workshop aimed at attracting the interest of novel research and advances contributing in the definition, representation and exploitation of health care knowledge in medical informatics. The 12 revised full research papers and 4 short papers presented in this book were carefully reviewed and selected from 26 submissions.
Knowledge Sharing in Chinese Hospitals
by Lihong Zhou José Miguel Baptista NunesThis book aims to identify, understand and qualify barriers to the patient-centred knowledge sharing (KS) in interprofessional practice of Traditional Chinese Medicine (TCM) and Western Medicine (WM) healthcare professionals in Chinese hospitals. This collaboration is particularly crucial and unique to China since, contrary to Western practice, these two types of professionals actually work together complimentary in the same hospital. This study adopted a Grounded Theory approach as the overarching methodology to guide the analysis of the data collected in a single case-study design. A public hospital in central China was selected as the case-study site, at which 49 informants were interviewed by using semi-structured and evolving interview scripts. The research findings point to five categories of KS barriers: contextual influences, hospital management, philosophical divergence, Chinese healthcare education and interprofessional training. Further conceptualising the research findings, it is identified that KS is mostly prevented by philosophical and professional tensions between the two medical communities. Therefore, to improve KS and reduce the effects of the identified barriers, efforts should be made targeted at resolving both types of tensions. The conclusion advocates the establishment of national policies and hospital management strategies aimed at maintaining equality of the two medical communities and putting in place an interprofessional common ground to encourage and facilitate communication and KS.
Knowledge Transformation in Health and Social Care: Putting Mindlines to Work
by Andrée Le May John GabbayThe term ‘mindlines’ has become common currency in the world of research implementation and evidence-based practice. This book updates, develops and applies the mindlines model more widely. It sheds light on how we can realistically mobilise and transform research-based evidence into practice in context. This illuminating book shows how the mindlines model can be put to work. It highlights how practitioners collectively share and internalise implicit, flexible ways of rapidly handling complex clinical situations. Drawing on research and reflective studies from practice, education, and guidelines-development across a wide range of international health and care settings, the authors unpack the general components of mindlines. They find practical ways to uncover, bring together and apply specific mindlines to improve practice; and to develop evidence-based healthcare policy, practice and education in ways that capitalise on the crucial role of mindlines. Closely edited by the originators of the mindlines model, this book brings together the work of a cohesive group of researchers and practitioners to showcase and develop its theory and consequences. It is an essential read for all those interested in knowledge mobilisation, evidence-based practice, and research implementation both within healthcare and beyond.
Knowledge Translation in Health Care: Moving from Evidence to Practice
by Ian D. Graham Jacqueline Tetroe Sharon E. StrausHealth care systems worldwide are faced with the challenge of improving the quality of care. Providing evidence from health research is necessary but not sufficient for the provision of optimal care and so knowledge translation (KT), the scientific study of methods for closing the knowledge-to-action gap and of the barriers and facilitators inherent in the process, is gaining significance. Knowledge Translation in Health Care explains how to use research findings to improve health care in real life, everyday situations. The authors define and describe knowledge translation, and outline strategies for successful knowledge translation in practice and policy making. The book is full of examples of how knowledge translation models work in closing the gap between evidence and action. Written by a team of authors closely involved in the development of knowledge translation this unique book aims to extend understanding and implementation worldwide. It is an introductory guide to an emerging hot topic in evidence-based care and essential for health policy makers, researchers, managers, clinicians and trainees.
Knowledge Translation in Health Care: Moving from Evidence to Practice
by Ian D. Graham Jacqueline Tetroe Sharon E. StrausKnowledge Translation in Health Care is a practical introduction to knowledge translation for everyone working and learning within health policy and funding agencies, and as researchers, clinicians and trainees. Using everyday examples, it explains how to use research findings to improve health care in real life. This new second edition defines the principles and practice of knowledge translation and outlines strategies for successful knowledge translation in practice and policy making. It includes relevant real world examples and cases of knowledge translation in action that are accessible and relevant for all stakeholders including clinicians, health policy makers, administrators, managers, researchers, clinicians and trainees. From an international expert editor and contributor team, and fully revised to reflect current practice and latest developments within the field, Knowledge Translation in Health Care is the practical guide for all health policy makers and researchers, clinicians, trainee clinicians, medical students and other healthcare professionals seeking to improve healthcare practice.
Knowledge Translation in Nursing and Healthcare: A Roadmap to Evidence-informed Practice
by Ian D. Graham Margaret B. HarrisonKnowledge Translation in Nursing and Healthcare provides authoritative guidance on the implementation of evidence-informed practice, covering issue identification and clarification, solution building and implementation, evaluation, and sustainment. Integrating theory, empirical research, and experiential knowledge, this hands-on resource assists nurses and healthcare practitioners in collecting quality evidence, transforming it into a useable, customized recommendation, and then applying best practice in various point-of-care settings. Written by highly experienced implementation researchers working with practitioners, the book demonstrates how the synthesis and translation of evidence supports improvement of existing care and service delivery models, and produces increased benefit for both patients and health services. Examples drawn from the authors' first-hand experience—such as pressure injury prevention in acute care, transition of care for people with heart failure, and community leg ulcer care—illustrate the use of best practice in addressing care and quality issues. This important reference and guide: Outlines a planning framework that activates research and evidence in practice settings, moving knowledge into action and sustaining the use of best practice Introduces the framework that enables effective evidence-informed methodology and decision-making Features numerous illustrative field examples of both successful and unsuccessful implementations in a variety of practical situations Offers perspectives on best practice implementation from experienced practitioners and researchers Knowledge Translation in Nursing and Healthcareis a must-have for those wanting to implement, evaluate, and sustain best practice in the delivery of evidence-informed healthcare to patients, families, and communities.
Knowledge in the Time of Cholera: The Struggle Over American Medicine in the Nineteenth Century
by Owen WhooleyVomiting. Diarrhea. Dehydration. Death. Confusion. In 1832, the arrival of cholera in the United States created widespread panic throughout the country. For the rest of the century, epidemics swept through American cities and towns like wildfire, killing thousands. Physicians of all stripes offered conflicting answers to the cholera puzzle, ineffectively responding with opiates, bleeding, quarantines, and all manner of remedies, before the identity of the dreaded infection was consolidated under the germ theory of disease some sixty years later. These cholera outbreaks raised fundamental questions about medical knowledge and its legitimacy, giving fuel to alternative medical sects that used the confusion of the epidemic to challenge both medical orthodoxy and the authority of the still-new American Medical Association. In Knowledge in the Time of Cholera, Owen Whooley tells us the story of those dark days, centering his narrative on rivalries between medical and homeopathic practitioners and bringing to life the battle to control public understanding of disease, professional power, and democratic governance in nineteenth-century America.
Knowledge-Based Bioinformatics
by Gil Alterovitz Marco RamoniThere is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in personalized medicine.Key Features:Explores the fundamentals and applications of knowledge-based and statistical approaches in bioinformatics and systems biology.Helps readers to interpret genomic, proteomic, and metabolomic data in understanding complex biological molecules and their interactions.Provides useful guidance on dealing with large datasets in knowledge bases, a common issue in bioinformatics.Written by leading international experts in this field.Students, researchers, and industry professionals with a background in biomedical sciences, mathematics, statistics, or computer science will benefit from this book. It will also be useful for readers worldwide who want to master the application of bioinformatics to real-world situations and understand biological problems that motivate algorithms.
Knowledge-Driven Board-Level Functional Fault Diagnosis
by Krishnendu Chakrabarty Fangming Ye Zhaobo Zhang Xinli GuThis book provides a comprehensive set of characterization, prediction, optimization, evaluation, and evolution techniques for a diagnosis system for fault isolation in large electronic systems. Readers with a background in electronics design or system engineering can use this book as a reference to derive insightful knowledge from data analysis and use this knowledge as guidance for designing reasoning-based diagnosis systems. Moreover, readers with a background in statistics or data analytics can use this book as a practical case study for adapting data mining and machine learning techniques to electronic system design and diagnosis. This book identifies the key challenges in reasoning-based, board-level diagnosis system design and presents the solutions and corresponding results that have emerged from leading-edge research in this domain. It covers topics ranging from highly accurate fault isolation, adaptive fault isolation, diagnosis-system robustness assessment, to system performance analysis and evaluation, knowledge discovery and knowledge transfer. With its emphasis on the above topics, the book provides an in-depth and broad view of reasoning-based fault diagnosis system design. * Explains and applies optimized techniques from the machine-learning domain to solve the fault diagnosis problem in the realm of electronic system design and manufacturing; * Demonstrates techniques based on industrial data and feedback from an actual manufacturing li≠ * Discusses practical problems, including diagnosis accuracy, diagnosis time cost, evaluation of diagnosis system, handling of missing syndromes in diagnosis, and need for fast diagnosis-system development.
Koenig and Schultz's Disaster Medicine
by Kristi L. Koenig Carl H. Schultz Koenig, Kristi L. and Schultz, Carl H.As societies become more complex and interconnected, the global risk for catastrophic disasters is increasing. Demand for expertise to mitigate the human suffering and damage these events cause is also high. A new field of disaster medicine is emerging, offering innovative approaches to optimize disaster management. Much of the information needed to create the foundation for this growing specialty is not objectively described or is scattered among multiple different sources. Now, for the first time, a coherent and comprehensive collection of scientific observations and evidence-based recommendations with expert contributors from around the globe is available in Koenig and Schultz's Disaster Medicine: Comprehensive Principles and Practices. This definitive work on disaster medicine identifies essential subject matter, clarifies nomenclature, and outlines necessary areas of proficiency for healthcare professionals handling mass casualty crises. It also describes in-depth strategies for the rapid diagnosis and treatment of victims suffering from blast injuries or exposure to chemical, biological, and radiological agents.
Koenig and Schultz's Disaster Medicine: Comprehensive Principles and Practices
by Kristi L. Koenig Carl H. SchultzAs societies become more complex and interconnected, the global risk for catastrophic disasters is increasing. Demand for expertise to mitigate the human suffering and damage these events cause is also high. A new field of disaster medicine is emerging, offering innovative approaches to optimize disaster management. Much of the information needed to create the foundation for this growing specialty is not objectively described or is scattered among multiple different sources. Now, for the first time, a coherent and comprehensive collection of scientific observations and evidence-based recommendations with expert contributors from around the globe is available in Koenig and Schultz's Disaster Medicine: Comprehensive Principles and Practices. This definitive work on Disaster Medicine identifies essential subject matter, clarifies nomenclature, and outlines necessary areas of proficiency for healthcare professionals handling mass casualty crises. It also describes in-depth strategies for the rapid diagnosis and treatment of victims suffering from blast injuries or exposure to chemical, biological, and radiological agents.
Kognitiv-behaviorale Psychotherapie von Ängsten: Kurztherapie mit Hypnose - die Praxisanleitung (Psychotherapie: Praxis)
by Hans-Christian KossakIn diesem Praxismanual erfahren Psychotherapeuten, wie sie mit Kurztherapie bei vielen Patienten mit Ängsten schnell und dauerhaft wirksam werden können. Dr. Kossak kombiniert die beiden effektiven Methoden Hypnose und kognitive Verhaltenstherapie: Sie wirkt meist bereits unmittelbar nach nur einer Sitzung. Klar gegliedert führt der Autor in die zugrundeliegenden Theorien der Methode ein, die dann im umfangreichen Praxisteil direkt nutzbar werden. Die Falldarstellungen mit Studienfragen machen diese Behandlung konkret nachvollziehbar. Die Effektivität ist durch große, anhaltende Katamnesezeiträume belegt. Geschrieben für ... Psychotherapeuten, Ärzte, Psychiater, Psychologen, Zahnärzte, Coaches und Studierende in diesen Fächern. Über den Autor: Dr. Hans-Christian Kossak, Dipl.-Psych., Psychologischer Psychotherapeut und Kinder- und Jugendlichenpsychotherapeut mit Ausbildungszertifikaten in Verhaltenstherapie, Gesprächspsychotherapie, Hypnosetherapie. Gründer der Psychotherapie in der Kombination von kognitiver Verhaltenstherapie und Hypnose. Schwerpunkt: Ängste, Psychosomatik, Lern- und Leistungsstörungen. Er war Leiter der Katholischen Beratungsstelle für Erziehungs- und Familienfragen, Bochum; Dozent und Ausbilder von Psychotherapeuten in Hypnose und Verhaltenstherapie; Referent auf Fachkongressen. Autor zahlreicher wissenschaftlicher Fachartikel und Fachbücher.
Kognitive Erhaltungstherapie bei rezidivierender Depression
by Ulrich Stangier Thomas Heidenreich Martin Hautzinger Anne Kathrin RischRezidivierende Depression: Rückfälle verhindern, psychische Gesundheit erhalten Depressionen gehören zu den häufigsten psychischen Störungen. Von dem Anteil der Betroffenen, die Therapie erhalten, erlebt eine hohe Anzahl Rückfälle - das ist anstrengend für Betroffene und Therapeuten. Und das ist teuer für Krankenkassen und Arbeitgeber. Problem: Die "Rückfälligen" werden bisher jeweils wie akut Erkrankte behandelt, ohne dass die Vorgeschichte berücksichtigt wird. Neue Forschungen zeigen: Erst die Mischung von klassisch verhaltenstherapeutischen Interventionen mit Maßnahmen aus dem nichtklinischen Bereich (z.B. Achtsamkeit, Akzeptanz, psychologisches Wohlbefinden, Werteorientierung) bringt den vollen Erfolg. Praxisorientiert: Aufbau am Bedarf der Praktiker orientiert Dieses Buch ist geschrieben für Verhaltenstherapeuten in Ausbildung und Praxis, klinische Psychologen, Psychiater, psychologische und ärztliche Psychotherapeuten - und gliedert sich in 3 Teile: Symptomatik, Klassifikation, Epidemiologie, Diagnostik der rezidivierenden Depression.Therapieprogramm in 6 Modulen (für die Arbeit im Einzelsetting).Alle nötigen Arbeitsmaterialien (und zwei Hörbeispiele für angeleitete Übungen), die der Therapeut bei seiner Arbeit braucht (auf CD-ROM).Mit CD-ROM: Alle Arbeitsblätter zum Ausdrucken plus 2 Podcasts mit Übungen
Kognitive Verhaltenstherapie bei Hypochondrie und Krankheitsangst: Mit 18 Abbildungen, 23 Tabellen Und 26 Arbeitsbla¨ttern (Psychotherapie: Praxis)
by Florian Weck Gaby BleichhardtDas Behandlungsmanual gibt Psychotherapeuten eine umfassende Anleitung zum Umgang mit krankheitsängstlichen Patienten. Von Ärzten und Psychotherapeuten wird diese Klientel zum Teil als schwierig empfunden – umso wichtiger ist die fachkundige, auf die Patientengruppe abgestimmte psychotherapeutische Behandlung. Die Angst vor Krankheit und Tod kennt jeder, es sind Urängste des Menschen. Massive und andauernde Krankheitsangst ist eine ernstzunehmende psychische Störung, die mit persönlichem Leid und psychosozialen Beeinträchtigungen einhergehen kann.Aus dem Inhalt: I Grundlagen: (1) Symptome des Störungsbildes – (2) Diagnostik, Epidemiologie, kognitiv-behaviorales Gesamtmodell – (3) Aktueller wissenschaftlicher Stand zu Hypochondrie und Krankheitsangst. – II Praxis: (1) Manualisiertes, kognitiv-behaviorales Programm für die Einzeltherapie, plus Übungen und Module für Therapiegruppen – (2) Hilfestellung für mögliche Komplikationen und Spezialfälle (z. B. Krankheitsangst bei vorhandenen Krankheiten) – (3) Verhaltensübungen, Formulierungsvorschläge und Dialogbeispiele, Arbeits- und Informationsblätter (zum Download und Ausdrucken im Internet).Über die Autoren: Dr. Gaby Bleichhardt arbeitet in der Leitung der Psychotherapie-Ambulanz Marburg an der Philipps-Universität Marburg. Prof. Dr. Florian Weck leitet die Abteilung für Klinische Psychologie und Psychotherapie an der Universität Potsdam.
Kognitive Verhaltenstherapie bei medizinisch unerklärten Körperbeschwerden und somatoformen Störungen
by Wolfgang Hiller Maria Kleinstäuber Petra Thomas Michael WitthöftJeder fünfte Patient in Deutschland leidet an organischen Beschwerden, ohne dass jemals eine Ursache gefunden wird. Um unnötige diagnostische Verfahren und falsche Behandlungen zu vermeiden, bieten sich vor allem die kognitiven Therapien an. Dieses erste Manual seiner Art liefert einen Leitfaden zur kognitiven Verhaltenstherapie in sieben strukturierten Einzelmodulen und gibt Therapeuten klare Anweisungen. Der Band enthält Arbeitsblätter und weitere Materialien zur unmittelbaren Nutzung.
Kognitive Verhaltenstherapie depressiven Grübelns
by Ruth Von Brachel Tobias Teismann Ulrike Willutzki Sven HanningGrübeln gilt als ein zentraler Faktor sowohl für die Entstehung und Fortdauer depressiver Störungen wie auch für Rückfälle. Das Manual bietet die erste deutschsprachige Anleitung zur Therapie depressiven Grübelns. Basierend auf aktuellen Befunden der Grundlagenforschung wird die Gestaltung einer gruppentherapeutischen Behandlung detailliert beschrieben und theoretisch fundiert erläutert. Die vorgeschlagenen therapeutischen Strategien lassen sich auch bei Einzeltherapien einsetzen. Mit Arbeitsmaterial und Hörübungen auf beiliegender CD-ROM.
Kognitive Verhaltenstherapie depressiven Grübelns
by Ruth Von Brachel Tobias Teismann Ulrike Willutzki Sven HanningDieses Buch zeigt Psychotherapeuten, Psychiatern und Beratern detailliert die Gestaltung einer gruppentherapeutischen Behandlung und ist angepasst an die Behandlung von Patienten, die an leichteren Formen unipolarer Depressionen leiden. Sämtliche der beschriebenen therapeutischen Strategien lassen sich zudem im einzeltherapeutischen Kontext nutzen. Die Arbeitsblätter im Buch stehen im Internet zum Download zur Verfügung. Dort finden sich auch vier Hörübungen für Patienten.Aus dem InhaltI Theorie – II Praxis und Behandlungsmanual – Teilnehmermaterialien.
Kognitive Verhaltenstherapie für Patienten mit leichter Alzheimer-Demenz und ihre Angehörigen
by Simon Forstmeier Tanja RothDieses Manual bietet erstmals ein umfassendes psychotherapeutisches Behandlungsprogramm für Personen mit einer beginnenden Alzheimer-Demenz und ihre Angehörigen auf Basis der kognitiven Verhaltenstherapie. Das Therapiekonzept beinhaltet sowohl etablierte verhaltenstherapeutische Interventionen wie Aktivitätenaufbau, aber auch alterspsychotherapeutische Elemente wie einen strukturierten Lebensrückblick sowie paartherapeutische Interventionen. Das Behandlungsprogramm wurde bereits erfolgreich wissenschaftlich evaluiert. Der Leser findet eine Anleitung für jede Sitzung und alle dazugehörigen Arbeitsmaterialien für die Patienten.Geschrieben für Psychologische und Ärztliche Psychotherapeuten, Psychiater, Hausärzte mit gerontologischem Schwerpunkt, Klinische Neuropsychologen.Aus dem InhaltI Grundlagen – II Therapie – III Materialien. Alle Materialien zum Download im Internet.
Kognitives Training bei psychiatrischen Erkrankungen: Empfehlungen für Psychiater, Neuropsychologen und Ergotherapeuten (Psychotherapie: Manuale)
by Daniela Roesch-Ely Katlehn BaumZahlreiche psychiatrische Erkrankungen gehen mit kognitiven Störungen einher, die die Alltagsfunktionalität der Patienten teils erheblich einschränken. In diesem Buch geben die Herausgeberinnen einen Überblick über kognitive Störungen bei ausgewählten Erkrankungen wie Schizophrenie, affektiven Erkrankungen, adultem ADHS und Autismus-Spektrum-Störungen und präsentieren praxisnahe Empfehlungen zu Planung, Struktur und praktischer Umsetzung entsprechender kognitiver Trainingsprogramme. Abgerundet wird das Manual durch entsprechende Fallbeispiele sowie verschiedene Informations- und Arbeitsblätter, die zum Download zur Verfügung stehen.Dieses Manual entstand in der Psychiatrischen Ambulanz für Kognitives Training (PAKT) des Universitätsklinikums Heidelberg und richtet sich an Psychiater, Neuropsychologen und Ergotherapeuten, die Patienten mit psychiatrischen Erkrankungen und assoziierten kognitiven Defiziten behandeln.
Kognitives Training in der Ergotherapie: Praktische Übungen zur Verbesserung der Konzentration
by Steffen KerskenDieses Praxisbuch liefert alles Wesentliche für das kognitive Training in der Ergotherapie. Welche Assessments sind zur Erfassung der Hirnleistung sinnvoll? Eignet sich eine ergotherapeutische Übung zur Förderung von Konzentration? Wie kann ich meine Patient*innen hinsichtlich Problemlösungs- und Entscheidungsfähigkeit unterstützen? Hier finden Sie die Antworten zu allen Aspekten des Hirnleistungstrainings. Aus dem Inhalt: Kreative und handlungsorientierte Übungen auf Basis eines sechssäuligen Therapiekonzeptes, Berufsbelastungsübungen, Präsentationen und Arbeitsstrategien, Förderung von Konzentration, Belastbarkeit und Aufmerksamkeit, Pausen- und Energiemanagement, Stressbewältigung mit zusätzlichen Arbeitsblättern zum Download.Gönnen Sie sich und Ihren Patient*innen etwas Abwechslung und bereichern Sie Ihr Behandlungsrepertoire um eine Vielzahl von kreativen Übungen.
Koht, Sloan, Toleikis's Monitoring the Nervous System for Anesthesiologists and Other Health Care Professionals
by Christoph N. Seubert Jeffrey R. BalzerAs a single-source volume on intraoperative neurophysiological monitoring (IOM), previous editions of this celebrated resource amounted to a mission statement from the pioneer generation in intraoperative neurophysiology, converting insights, techniques, and perspectives into tools providing clinical utility for the assessment of the nervous system in patients who could not be assessed by a standard neurological examination. Now directed by a new generation of experts, this thoroughly illustrated Third Edition is updated with new case material, images, videos, practice guidelines, references, and technologies, and is intended for those who encounter IOM in the operating room and intensive care unit, including anesthesiologists, technologists, neurophysiologists, surgeons, and nurses, as well as graduate students and trainees. Offering topical, applicable information, this accessible reference and teaching tool provides practical knowledge to help students, trainees, and team members better understand one another’s roles, thereby improving patient safety and care.
Koku in Food Science and Physiology: Recent Research on a Key Concept in Palatability
by Toshihide Nishimura Motonaka KurodaThis is the first book to explore the science underlying the concept of “koku”, which is central to an understanding of the palatability of food within Japanese cuisine and is attracting increasing interest among food scientists and professionals worldwide. Koku may be defined as the sensation that results from the complexity of the food (i.e., its richness or body), its lingering aftertaste or persistence, and its heartiness in terms of taste, aroma, and texture. A variety of substances have been found to impact significantly on koku, including umami substances, phytosterols, certain aromatic compounds, and kokumi substances. In Koku – Food Science and Physiology, readers will find full explanation of the conceptual aspects and the latest research results on a wide range of topics, including the relevant flavor chemistry and sensory analysis. Written by leading scientists in the field, the book will be a valuable resource for students and researchers in the fields of food chemistry, nutritional science, taste physiology, and neuroscience, as well as for professionals in the food industry.
Kokumi Substance as an Enhancer of Koku: Biochemistry, Physiology, and Food Science
by Motonaka KurodaThis book provides the basic concepts and latest findings on kokumi substances. It covers not only the topics related to food chemistry, but also the biochemical and physiological mechanisms of the perception of kokumi substances. Food palatability is determined by many factors, including taste, aroma, texture, color, physiological condition, and circumstances. The attribute called “koku” is used in Japan to express delicious foods. The definition of koku attribute was previously proposed to be caused by the sensation of richness, body, lingering (continuity), and mouthfulness in terms of taste, aroma, and texture. Kokumi substance is one of the taste-related koku enhancers and is defined as a substance that enhances complexity, richness (body), and lastingness (continuity), although it has no taste itself at the dose. The topics in this book cover physiological studies, including the receptor mechanism, taste nerve recording, and human brain responses using functional MRI. It also discusses the sensory characteristics of kokumi substances when added to foods and the effect of kokumi substances on the satiety. The intended readers are university students, researchers and technologists in food science, food chemistry, nutritional sciences, taste physiology, and neuroscience. Non-expert readers interested in food palatability and the deliciousness of foods may also find this book useful.