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Label-Free Biosensor Methods in Drug Discovery
by Ye FangThis volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but may introduce artifacts in assay results. Addressing several fundamental and practical aspects as to how to implement label-free methods in the drug discovery process, this book covers a wide range of topics, including binding kinetics determination, fragment screening, antibody epitope mapping, protein-protein interaction profiling and screening, receptor pathway deconvolution, drug pharmacology profiling and screening, target identification, drug toxicity assessment, and physical phenotype profiling and diagnostics based on various cellular processes such as cell adhesion, migration, invasion, infection, and inflammation. As part of the Methods in Pharmacology and Toxicology series, chapters aim to provide key detail and implementation advice to aid with progress in the lab. Practical and thorough, Label-Free Biosensor Methods in Drug Discovery provides a new avenue for rapid access to a focused collection of highly regarded contributions in the field.
Label-Free Monitoring of Cells in vitro (Bioanalytical Reviews #2)
by Joachim WegenerThis book is dedicated to label-free, non-invasive monitoring of cell-based assays and it comprises the most widely applied techniques. Each approach is described and critically evaluated by an expert in the field such that researchers get an overview on what is possible and where the limitations are. The book provides the theoretical basis for each technique as well as the most successful and exciting applications.Label-free bioanalytical techniques have been known for a long time as valuable tools to monitor adsorption processes at the solid-liquid interface in general – and biomolecular interaction analysis (BIA) in particular. The underlying concepts have been progressively transferred to the analysis of cell-based assays. The strength of these approaches is implicitly given with the name 'label-free': the readout is independent of any label, reagent or additive that contaminates the system under study and potentially affects its properties. Thus, label-free techniques provide an unbiased analytical perspective in the sense that the sample is not manipulated by additives but pure. They are commonly based on physical principles and read changes in integral physical properties of the sample like refractive index, conductivity, capacitance or elastic modulus to mention just a few. Even though it is not implied in the name, label-free approaches usually monitor the cells under study non-invasively meaning that the amplitude of the signal (e.g. electric field strength, mechanical elongation) that is used for the measurement is too low to interfere or affect. In contrast to label-based analytical techniques that are commonly restricted to a single reading at a predefined time point, label-free approaches allow for a continuous observation so that the dynamics of the biological system or reaction become accessible.
Label-Free Super-Resolution Microscopy (Biological and Medical Physics, Biomedical Engineering)
by Vasily AstratovThis book presents the advances in super-resolution microscopy in physics and biomedical optics for nanoscale imaging. In the last decade, super-resolved fluorescence imaging has opened new horizons in improving the resolution of optical microscopes far beyond the classical diffraction limit, leading to the Nobel Prize in Chemistry in 2014. This book represents the first comprehensive review of a different type of super-resolved microscopy, which does not rely on using fluorescent markers. Such label-free super-resolution microscopy enables potentially even broader applications in life sciences and nanoscale imaging, but is much more challenging and it is based on different physical concepts and approaches. A unique feature of this book is that it combines insights into mechanisms of label-free super-resolution with a vast range of applications from fast imaging of living cells to inorganic nanostructures. This book can be used by researchers in biological and medical physics. Due to its logically organizational structure, it can be also used as a teaching tool in graduate and upper-division undergraduate-level courses devoted to super-resolved microscopy, nanoscale imaging, microscopy instrumentation, and biomedical imaging.
Label-Free Technologies For Drug Discovery
by Matthew Cooper Lorenz M. MayrOver the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories.Label-Free Technologies For Drug Discovery summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery.Label-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult target classes, cell-based receptor/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.Label-Free Technologies For Drug Discovery is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis.
Labeling the Mentally Retarded: Clinical and Social System Perspectives on Mental Retardation
by Jane R. MercerThis eight-year study of an American city traces the answer to the question "Who is retarded?" by analyzing the labeling process in a large number of community agencies. Data for the study are drawn from a representative sample of 7,000 persons under fifty years of age who were tested ans screened for "symptoms" of mental retardation. The author finds that that schools label more persons as mentally retarded than any other agency and share their labels more widely with others in the community. Relying on IQ test scores for diagnosis, schools place many persons with scores above 70 and with no physical disabilities in the role of retardate. The author contends that both the statistical model of "normal" and the unicultural viewpoint of educators and clinicians work to the disadvantage of the poor and the ethnic minorities. Given the opportunity, many persons demonstrate by their ability to cope with the problems in other areas of life that they are not comprehensively incompetent. The author makes serval policy recommendations. First, she suggests lowering the IQ score cutoff point used by schools in determining who shall be labeled as retarded. Second, she recommends that the clinicians use the two-dimensional definition of retardation proposed by the American Association of Mental Deficiency, subnormality in both intellectual performance and adaptive behavior. Third, she concludes that pluralistic assessment procedures must be employed to take into account cultural biases in IQ tests designed to measure cognitive skills. This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1973.
Labioplastik – Topographie und Varianten: Von der Theorie zur klinischen Praxis
by Rafael Sánchez-Borrego Pablo Gonzales-IsazaDieses Buch bietet dem Leser eine Beschreibung der Hypertrophie der kleinen Schamlippen und der Verlängerung des Klitorismantels in Bezug auf anatomische Varianten. Die Expertenbeiträge stellen ihre Technik der topografischen Schamlippenkorrektur vor, die es dem Chirurgen ermöglicht, die chirurgischen Ergebnisse zu verbessern und Komplikationen sowie schlechte ästhetische Ergebnisse zu vermeiden. Dies ermöglicht es Chirurgen auch, die enormen anatomischen Varianten im Zusammenhang mit der Hypertrophie der kleinen Schamlippen und dem Klitorisfrenulum-Komplex zu verstehen, mit dem Ziel, ein besseres Ergebnis aus ästhetischer und funktioneller Sicht zu erzielen. Die achtzehn verständlich geschriebenen Kapitel umfassen eine kurze historische Recherche über die Geschichte der Schamlippenkorrektur, Klassifikationen der Hypertrophie der kleinen Schamlippen, Indikationen und Kontraindikationen für die Operation, anästhetische Überlegungen, chirurgische Instrumente, rekonstruktive Aspekte, Schamlippenkorrektur bei Teenagern und dem Einfluss auf die Sexualität. Das Buch enthält auch chirurgische Videos. Topografische Schamlippenkorrektur - Von der Theorie zur Praxis richtet sich an Fachärzte für Gynäkologie, plastische Chirurgie, Urogynäkologie und diejenigen, die sich für kosmetische Genitalchirurgie bei Frauen interessieren.
Labor and Delivery Care
by Wayne R. Cohen Emanuel A. FriedmanLabor and Delivery Care: A Practical Guide supports and reinforces the acquisition of the practical obstetric skills needed for aiding a successful birth.Beginning with the most important element of successful labor care, communicating with the patient, the authors guide you through normal delivery routines and examination techniques. They then address the best approaches to the full range of challenges that can arise during labor and delivery. Throughout, the 15 chapters provide concise practical guidance with:algorithmic decision treesclinical management tipsdetailed drawingsLabor and Delivery Care: A Practical Guide provides a thorough tour-de-force of the practical obstetric skills needed for best and safest practice based on clinical experience and evidence.
Labor of Love: Gestational Surrogacy and the Work of Making Babies
by Heather JacobsonWhile the practice of surrogacy has existed for millennia, new fertility technologies have allowed women to act as gestational surrogates, carrying children that are not genetically their own. While some women volunteer to act as gestational surrogates for friends or family members, others get paid for performing this service. The first ethnographic study of gestational surrogacy in the United States, Labor of Love examines the conflicted attitudes that emerge when the ostensibly priceless act of bringing a child into the world becomes a paid occupation. Heather Jacobson interviews not only surrogate mothers, but also their family members, the intended parents who employ surrogates, and the various professionals who work to facilitate the process. Seeking to understand how gestational surrogates perceive their vocation, she discovers that many regard surrogacy as a calling, but are reluctant to describe it as a job. In the process, Jacobson dissects the complex set of social attitudes underlying this resistance toward conceiving of pregnancy as a form of employment. Through her extensive field research, Jacobson gives readers a firsthand look at the many challenges faced by gestational surrogates, who deal with complicated medical procedures, delicate work-family balances, and tricky social dynamics. Yet Labor of Love also demonstrates the extent to which advances in reproductive technology are affecting all Americans, changing how we think about maternity, family, and the labor involved in giving birth. For more, visit http://www.heatherjacobsononline.com/
Laboratory Animal Medicine: Principles and Procedures
by Margi SiroisComprehensive coverage of a variety of topics such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations prepares readers for a career in laboratory animal medicine. Familiarizes readers with the handling, behavior, nutrition, and lab and treatment procedures for a large variety of common and nontraditional laboratory animals. The consistent organization of each species chapter makes it easy for readers to quickly identify similarities and differences among various laboratory animals. Laboratory exercises are included in a perforated section at the end of the book, allowing users to apply their knowledge and develop job skills. Features a wealth of user-friendly features such as a two-color design, learning objectives, key points, and review questions. Provides detailed information on specific legal and ethical requirements of lab animal care and use, including the ethics of pain management. Convenient boxes and tables provide quick access to,important anatomic and physiologic data for each species.
Laboratory Animal and Exotic Pet Medicine
by Margi SiroisLearn the veterinary technician's role in the care of exotic pets and animals used in biomedical research! Laboratory Animal and Exotic Pet Medicine: Principles and Procedures, 3rd Edition helps you gain the knowledge and skills needed to ensure animal health and well-being. It covers animal husbandry, restraint and handling, and diseases, and provides guidelines to key clinical procedures such as blood collection, medication administration, anesthesia, and diagnostic imaging. Research-related information addresses the ethical concerns of exotic pet ownership, as well as the benefits and humane use of animals in research. Written by noted veterinary technology educator Margi Sirois, this text is a must-have resource for all caretakers of lab animals. Comprehensive coverage prepares you to work with all types of animals by addressing a wide variety of species including rats, mice, rabbits, guinea pigs, ferrets, hamsters, gerbils, nonhuman primates, amphibians, fish, reptiles, birds, farm animals, and cats and dogs; it also covers topics such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations. Consistent organization of each species chapter makes it easy to quickly identify similarities and differences among various laboratory animals. Current information on legal, moral, and ethical issues includes legal requirements, the protocols guiding lab animal use, animal exploitation, and animal rights. Discussion of specific uses for each species in biomedical research provides a perspective that helps you explain the benefits of animal use in providing high-quality research data. Technician Notes highlight important points and provide helpful tips to improve your knowledge and skills. Learning objectives, key points, and chapter review questions make studying easier. NEW! Comprehensive coverage of poultry includes the increasingly popular backyard chickens, as well as commonly performed procedures and in-depth information on housing, restraint, nutrition, common diseases, diagnostics, and therapeutics. NEW photographs show the latest technology available in laboratory and exotic animal medicine.
Laboratory Auditing for Quality and Regulatory Compliance
by Donald C. Singer Raluca-Ioana Stefan Jacobus F. van StadenIdentifying current tools, techniques, and approaches for the evaluation of laboratory operations, this reference reviews the latest regulatory standards and auditing practices to test laboratory safety, quality, and performance.
Laboratory Biorisk Management: Biosafety and Biosecurity
by Reynolds M. Salerno Jennifer GaudiosoOver the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient.Setting the s
Laboratory Design Handbook
by E. Crawley CooperLaboratory Design Handbook describes the process, motivation, constraints, challenges, opportunities, and specific design data related to the creation of a modern research laboratory. The information presented is based on a large pool of experience in the development of new and renovated laboratory buildings for universities, teaching hospitals, ph
Laboratory Guide to Enzymology
by Geoffrey A. Holdgate Antonia Turberville Alice LanneLABORATORY GUIDE TO ENZYMOLOGY An accessible guide to understanding the foundations of enzymology at its application in drug discovery Enzymes are highly specialized proteins necessary for performing specific biochemical reactions essential for life in all organisms. In disease, the functioning of these enzymes can become altered and, therefore, enzymes represent a large class of key targets for drug discovery. In order to successfully target dysfunctional enzymes pharmaceutically, the unique mechanism of each enzyme must be understood through thorough and in-depth kinetic analysis. The topic of enzymology can appear challenging due its interdisciplinary nature combining concepts from biology, chemistry, and mathematics. Laboratory Guide to Enzymology brings together the theory of enzymology and associated lab-based work to offer a practical, accessible guide encompassing all three scientific disciplines. Beginning with a brief introduction to proteins and enzymes, the book slowly immerses the reader into the foundations of enzymology and how it can be used in drug discovery using modern methods of experimentation. The result is a detailed but highly readable volume detailing the basis of drug discovery research. Laboratory Guide to Enzymology readers will also find: Descriptions of key concepts in enzymology Examples of drugs targeting different enzymes via different mechanisms Detailed discussion about many areas of enzymology such as binding and steady-state kinetics, assay development, and enzyme inhibition and activation Laboratory Guide to Enzymology is ideal for all pharmaceutical and biomedical researchers working in enzymology and assay development, as well as advanced students in the biochemical or biomedical sciences looking to develop a working knowledge of this field of research.
Laboratory Guide to the Methods in Biochemical Genetics
by Nenad Blau Frédéric M. VazNow in its 2nd edition, this manual describes laboratory methodology for the diagnosis of inherited metabolic diseases. The book describes a spectrum of tests, from simple screening methods via classical methods that are operational in most (if not all) biochemical laboratories, to analytical methods that depend on technologies that very few are currently employing in their labs, but are certainly the functional techniques in a biochemical laboratory in this post-genomics era. Each chapter is sufficiently detailed to be self-contained, thus enabling laboratory specialists to adopt the method in their own laboratory and obviating the need for additional methods or references. The second updated edition of the book is unique in that it is the first of its kind to be published in the last 13 years, and individual chapters have been developed by experts in the field citing both established and cutting-edge (omics) technology. Thus, it is an indispensable resource for researchers and clinicians working on the field of inherited metabolic diseases and those interested in laboratory diagnoses.
Laboratory Hematology Practice
by Bruce Davis Kandice Kottke-MarchantExpertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.
Laboratory Hemostasis
by Sterling T. Bennett Christopher M. Lehman George M. RodgersCoagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anticoagulant monitoring and management. This handbook provides practical information and guidance on topics relevant to directing a coagulation laboratory, filling a void in the literature. Since the first edition, all chapters have been updated and an entirely new chapter is included on pharmacogenomics and pharmacogenetics. The book will aid pathologists, clinical laboratory scientists and other physicians serving as laboratory directors to understand and carry out their responsibilities. It will also assist residents and fellows in learning the basics of coagulation testing and serve as a useful day-to-day reference for coagulation laboratory supervisors, technologists, and technicians. Finally, clinicians may find aspects of the book helpful in understanding the role of the coagulation laboratory in patient evaluation and monitoring.
Laboratory Imaging & Photography: Best Practices for Photomicrography & More (Applications in Scientific Photography)
by Michael PeresLaboratory Imaging and Photography: Best Practices for Photomicrography and More is the definitive guide to the production of scientific images. Inside, the reader will find an overview of the theory and practice of laboratory photography, along with useful approaches to choosing equipment, handling samples, and working with microscopic subjects. Drawing from over 150 years of combined experience in the field, the authors outline methods of properly capturing, processing and archiving the images that are essential to scientific research. Also included are chapters on applied close-up photography, artificial light photography and the optics used in today’s laboratory environment, with detailed entries on light, confocal and scanning electron microscopy. A lab manual for the digital era, this peerless reference book explains how to record visual data accurately in an industry where a photograph can serve to establish a scientific fact. Key features include: Over 200 full-color photographs and illustrations A condensed history of scientific photography Tips on using the Adobe Creative Suite for scientific applications A cheat sheet of best practices Methods used in computational photography
Laboratory Investigations of Thrombophilia: Clinical and Practical Aspects
by Akbar Dorgalaleh Anvarjon SamadovThis comprehensive book offers an in-depth overview of laboratory diagnoses for both inherited and acquired thrombophilias, illuminating the complex interplay between genetic and environmental factors that contribute to venous thromboembolism. Beginning with foundational concepts in thrombophilia testing, the book systematically covers the diagnosis of key anticoagulant deficiencies, including protein C, protein S, protein Z, antithrombin, and plasminogen, as well as the critical evaluation of prothrombin G20210A and factor V Leiden mutations and other factors involved in thrombosis. It also addresses acquired thrombophilia, highlighting the significant impact of factors such as hyperhomocysteinemia and the influence of medications, lifestyle choices, and underlying health conditions on thrombosis risk. Each chapter clarifies the principles behind various laboratory assays, detailing the preanalytical variables that can affect results and guiding the interpretation of findings. Real-world challenges in thrombophilia testing such as during pregnancy, the use of oral contraceptives, and monitoring anticoagulation therapy are specifically examined. Written in a clear yet comprehensive style, this book is aimed at thrombosis specialists, hematologists, laboratory scientists, and students. It provides extensive knowledge, practical guidance, and evidence-based protocols for thrombophilia testing, ensuring accurate diagnosis and effective management of this life-threatening disorder.
Laboratory Manual For Anatomy And Physiology Featuring Martini Art, Main Version
by Michael WoodThis laboratory manual is designed to serve the lab course that accompanies the two-semester anatomy and physiology lecture course. It provides students with comprehensive coverage of anatomy and physiology, beautiful full-color art and photographs, and an intuitive pedagogical framework. The primary goals of this manual are to provide students with hands-on experiences that reinforce the information they learn in the lecture course and to help them understand three-dimensional relationships, visualize complex structures, and comprehend intricate physiological processes. The manual is written to correspond to all current two-semester anatomy and physiology textbooks, although those students and instructors using Fundamentals of Anatomy & Physiology, Tenth Edition, by Frederic H. Martini, Judi L. Nath, and Edwin F. Bartholomew will recognize here some of the superb art from that text by William Ober and Claire Garrison, Martini's renowned biomedical illustrators. This sixth edition manual is available in three separate versions. The Main Version covers the full two-semester A&P curriculum, including dissections of the cow eye and of the sheep heart, brain, and kidney. The Cat Version includes all of the same material plus an additional section of nine cat dissection exercises encompassing the major body systems. The Pig Version, similarly, includes all of the material from the Main Version with a separate section of nine fetal pig dissection exercises. The Cat and Pig Versions make the manual more useful to instructors whose students perform animal dissections in the lab. The outstanding dissections and accompanying photographs are by Shawn Miller and Mark Neilsen and I thank each of them for their expertise.
Laboratory Manual For Clinical Kinesiology And Anatomy (Fourth Edition)
by Lynn S. Lippert Mary Alice Duesterhaus MinorDivided into three sections, it will help you to prepare for lab, guide you through lab activities, and serve as an after-lab review that ensures you build a solid knowledge base of kinesiology.
Laboratory Manual for Biotechnology and Laboratory Science: The Basics, Revised Edition
by Lisa A. Seidman Mary Ellen Kraus Diana Lietzke Brandner Jeanette MoweryProvides the basic laboratory skills and knowledge to pursue a career in biotechnology. Written by four biotechnology instructors with over 20 years of teaching experience, it incorporates instruction, exercises, and laboratory activities that the authors have been using and perfecting for years. These exercises and activities help students understand the fundamentals of working in a biotechnology laboratory. Building skills through an organized and systematic presentation of materials, procedures, and tasks, the manual explores overarching themes that relate to all biotechnology workplaces including forensic, clinical, quality control, environmental, and other testing laboratories.Features:• Provides clear instructions and step-by-step exercises to make learning the material easier for students. There are Lab Notes for Instructors in the Support Material (see tab below).• Emphasizes fundamental laboratory skills that prepare students for the industry.• Builds students’ skills through an organized and systematic presentation of materials, procedures, and tasks.• Updates reflect recent innovations and regulatory requirements to ensure students stay up to date.• Supplies skills suitable for careers in forensic, clinical, quality control, environmental, and other testing laboratories.
Laboratory Manual for Classification and Morphology of Rumen Ciliate Protozoa
by B.A. DehorityThe only rumen protozoa lab guide featuring line drawings created by a leading scientist in the fieldLaboratory Manual for Classification and Morphology of Rumen Ciliate Protozoa is a unique lab guide for learning how to count and identify rumen protozoa. In this guide, Professor Dehority has created line drawings of rumen protozoa that emphasize morphological features and size measurements. The book also provides keys for identifying genera and species, and it contains classifications and descriptions of the different orders and families of rumen ciliate protozoa. Procedures for counting rumen protozoa and identifying individual species are included as well.Laboratory Manual for Classification and Morphology of Rumen Ciliate Protozoa will be an excellent identification guide for protozoologists, microbiologists, dairy scientists, and any researcher or student working with rumen protozoa.
Laboratory Manual for Clinical Anatomy and Physiology for Veterinary Technicians
by Joanna M. Bassert Thomas ColvilleLearn to apply your A&P learning in the lab setting with Colville and Bassert’s Lab Manual for Clinical Anatomy and Physiology for Veterinary Technicians, 3rd Edition. This practical laboratory resource features a variety of activities, such as crossword puzzles, , terminology exercises, illustration identification and labeling, case presentations, and more to help reinforce your understanding of veterinary anatomy and physiology. The lab manual also features vivid illustrations, lists of terms and structures to be identified, and step-by-step dissection guides to walk you through the dissection process. <P><P> Clinically-oriented learning exercises help readers become familiar with the language of anatomy and physiology as you identify structures and learn concepts. Clear step-by-step dissection instructions for complex organs such as the heart familiarize readers with the dissection process in a very visual, easy-to-understand format. Learning objectives, the clinical significance of the content, and lists of terms and structures to be identified appear at the beginning of each chapter. Comprehensive glossary appears at the end of the lab manual and provides accurate, concise. High quality, full color illustrations provides a firm understanding of the details of anatomic structure. Review activities and study exercises are included in every chapter to reinforce important information. Clinical Application boxes are threaded throughout the lab manual and demonstrate the clinical relevance of anatomic and physiologic principles. Companion Evolve site includes answers to the Test Yourself questions in the textbook and crossword puzzles. NEW! Overview at a Glance sections outline the main proficiencies of each chapter and include a list of all exercises in the chapter.
Laboratory Manual for Clinical Anatomy and Physiology for Veterinary Technicians
by Joanna M. Bassert Thomas P. ColvilleLearn to apply your A&P learning in the lab setting with the Laboratory Manual for Clinical Anatomy and Physiology for Veterinary Technicians, 4th Edition. This practical laboratory resource features a variety of activities, such as terminology exercises, illustration identification and labelling, case presentations, and more to help reinforce your understanding of veterinary anatomy and physiology. The laboratory manual also features vivid illustrations, lists of terms and structures to be identified, and step-by-step dissection guides to walk you through the dissection process. <p><p> Clinically oriented learning exercises introduce you to the language of anatomy and physiology as you identify structures and learn concepts. <p><p>Clear, step-by-step dissection instructions for complex organs such as the heart familiarize you with the dissection process in a very visual, easy-to-understand format. <p><p>Learning objectives, the clinical significance of the content, and lists of terms and structures to be identified appear at the beginning of each chapter. <p><p>Review activities and study exercises are included in every chapter to reinforce important information. <p><p>High-quality, full-color illustrations provide a solid understanding of the details of anatomic structure.