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Lifestyle Nutrition: Eating for Good Health by Lowering the Risk of Chronic Diseases (Lifestyle Medicine)

by James M. Rippe

What individuals consume in their diet has profound implications on their health. Despite overwhelming evidence that plant-based diets yield multiple health benefits, physicians often feel ill-prepared to discuss nutrition with their patients. Authored by renowned cardiologist Dr. James M. Rippe, Lifestyle Nutrition: Eating for Good Health by Lowering the Risk of Chronic Diseases provides physicians with an evidence-based introduction to nutrition science with a practical emphasis on how to apply this information to improve the health of their patients and enhance their own lives.From nutrition and atherosclerosis to erectile dysfunction and chronic kidney disease to osteoporosis, this comprehensive guide covers a wide range of conditions influenced by diet. It delves into specialized areas, such as nutrition for physically active people to the elderly, ensuring relevance for diverse patient populations. The reader will find detailed analysis of the Dietary Guidelines for Americans 2020–2025 and their applications and strategies for adopting healthy plant-based diets, such as Mediterranean, DASH, and vegan.Each chapter begins with key points and concludes with clinical applications, making it valuable to clinicians. As part of the esteemed Lifestyle Medicine Series, this is an indispensable resource for any healthcare provider committed to enhancing patient care through informed dietary practices.

Lifestyle Psychiatry: Through the Lens of Behavioral Medicine (Lifestyle Medicine)

by Gia Merlo Christopher P. Fagundes

Lifestyle medicine is a practice which adopts evidence-based lifestyle interventions as a primary modality to prevent, treat, and reverse chronic diseases. The six main pillars of this specialty include physical activity, nutrition, stress resilience, cessation or risk reduction of substance use, quality sleep, and connectivity. Lifestyle Psychiatry: Through the Lens of Behavioral Medicine is grounded in the same pillars, drawing upon theories, methods, and empirical findings from health psychology and behavioral medicine. Lifestyle psychiatry is a rapidly emerging area within healthcare informed by rigorous research within the social and biological sciences, public health, and medicine. A volume in the Lifestyle Medicine series, this book uses a comprehensive biopsychosocial approach to prevent and treat psychiatric disorders and promote mental and physical well-being through evidence-based lifestyle interventions. Features: Draws upon theories, methods, and empirical findings from health psychology and behavioral medicine. Provides evidence-based research on the bi-directionality of mental and physical health. Addresses fundamental neuroscience concepts and applies them to practical aspects of lifestyle practices, mental health, and brain health. Appropriate for clinicians, primary care physicians, and those practicing in specialized areas, the information in this book provides users with practical tools to help explain, prevent, and treat psychiatric disorders and associated maladaptive health behaviors in patients.

Lifestyle and Medicine in the Enlightenment: The Six Non-Naturals in the Long Eighteenth Century (Routledge Studies in the History of Science, Technology and Medicine)

by James Kennaway Rina Knoeff

The biggest challenges in public health today are often related to attitudes, diet and exercise. In many ways, this marks a return to the state of medicine in the eighteenth century, when ideals of healthy living were a much more central part of the European consciousness than they have become since the advent of modern clinical medicine. Enlightenment advice on healthy lifestyle was often still discussed in terms of the six non-naturals – airs and places, food and drink, exercise, excretion and retention, and sleep and emotions. This volume examines what it meant to live healthily in the Enlightenment in the context of those non-naturals, showing both the profound continuities from Antiquity and the impact of newer conceptions of the body.

Lifestyle in Medicine (Critical Studies in Health and Society)

by Gary Easthope Emily Hansen

In Western societies, 'lifestyle' as an explanation for health and illness has become increasingly popular. Lifestyle in Medicine explores the ambiguity of the term 'lifestyle' and the way it is conceived and applied within medicine. Based on real doctor-patient consultations and in-depth interviews with doctors, the book discusses: the history behind current medical use of lifestyle the variable usage of the 'lifestyle' concept in different medical settings critical writings and recent shifts in sociological thinking about lifestyle public and government concerns about unhealthy lifestyles the ways in which health is discussed, doctor to patient. Evidence-based in its approach, this book uses original research to highlight this topical issue and provides professional and lay perspectives on health and illness. It is essential reading for students and academics of medical sociology, health and allied health studies and anyone interested in health and society.

Life’s Blood: The Story of Hemoglobin

by Michael H. Rosove

Life’s Blood: The Story of Hemoglobin encompasses the entire clinically relevant story of hemoglobin, the only molecule we have that captures oxygen from the air we breathe and delivers it to our tissues to generate the energy without which we would not exist. Dr. Rosove covers first the discoveries of oxygen, hemoglobin, and circulation of the blood, then the structure and function of human hemoglobin, together with comparisons to other oxygen transporters in the animal kingdom. He examines the red blood cell and how it protects hemoglobin, with an in-depth look at malaria and the hemoglobin and red cell mutations malaria forced us to make defending ourselves against it, particularly sickle cell disease and the thalassemias. The author also explores adaptations to the oxygen-poor environment of high altitude; lessons from freak hemoglobin mutations; hemoglobin toxins including carbon monoxide and chemicals and drugs that cause oxidant damage; and the quest for a hemoglobin substitute. Life’s Blood is a comprehensive resource for physicians, nurses, and other health professionals, at any and every stage of career development. Even seasoned hematologists, internists, and hospitalists will find something new and informative on practically every page. The book’s approachable, engaging style will also appeal to science-minded readers who will appreciate being awakened to the workings of hemoglobin, a miraculous molecule.

Lifting Suspicion

by Gill Sanderson

All Dr. Megan Taylor wants is to carry on with her work as a SHO in the Obs and Gyne department of her hospital. She knows that on occasion people take advantage of her good nature, but she can cope with it. Then her happy world seems to be about to collapse when her former consultant is accused of a crime he cannot defend himself against, and Megan is named as his conspirator. New consultant Christian Firth is her complete opposite - while she is calm and docile, he enjoys a fight, but Megan finds herself drawn to him. When he shows an interest in her, he is more wary than she is - while they are falling in love with each other, he can't fully trust her until she clears her name.

Lifting Suspicion: An Opposites Attract Medical Romance (Medical Romances #11)

by Gill Sanderson

Another heartwarming medical romance from best-selling author Gill Sanderson! Perfect for fans of Mia Faye, Laura Scott, Helen Scott Taylor, Grey's Anatomy and ER.Readers LOVE Gill's gripping medical romances!'Empathy, sympathy, sensitivity! This writer has it all and more!' 5* reader review'A very easy enjoyable book to read, couldn't put it down' 5* reader review'Remarkable writer!!' 5* author review All Dr. Megan Taylor wants is to carry on with her work as a SHO in the Obs and Gyne department of her hospital. She knows that on occasion people take advantage of her good nature, but she can cope with it. Then her happy world seems to be about to collapse when her former consultant is accused of a crime he cannot defend himself against, and Megan is named as his conspirator. New consultant Christian Firth is her complete opposite - while she is calm and docile, he enjoys a fight, but Megan finds herself drawn to him. When he shows an interest in her, he is more wary than she is - while they are falling in love with each other, he can't fully trust her until she clears her name. Don't miss Gill Sanderson's enthralling medical romances, including the A Lakeland Practice and the Good, Bad and Ugly series.

Lifting Techniques in Plastic Surgery: A Practical Guide on Thread Lifting, Mini-Lifting and Rhytidectomy

by Won Lee Kyu Hwa Jung

This book discusses all the lifting procedures within the field of plastic surgery. It provides a simplified and easily understandable differentiation of traditional surgical rhytidectomy, as well as less invasive options such as mini-lifting and the globally popular thread lifting. The book compares the advantages and disadvantages of these methods, highlighting the limitations and outcomes of each surgical technique through photographic comparisons, enabling readers to determine the most suitable procedure for their patients. The book will also covers essential anatomy related to lifting, the aging process of patients, and the materials used in thread lifting. The aim is for this book to become a valuable resource for practitioners performing lifting procedures.

Ligamentous Injuries of the Foot and Ankle: Diagnosis, Management and Rehabilitation

by Kenneth J. Hunt Pieter D’Hooghe Jeremy J. McCormick

Aimed at sports medicine and foot and ankle clinicians globally who see and treat ligamentous injuries to the foot and ankle, the focus of this comprehensive text is on cutting-edge techniques in both non-surgical and surgical treatment, rehabilitation, and safe and expeditious return to sport. Techniques and technology move very rapidly in this space, and this book serves as a ready resource on current surgical and rehabilitation techniques for these conditions. Opening with a review of the relevant anatomy and biomechanics of the foot and ankle, as well as current imaging techniques, the text then turns to the diagnosis, management and rehabilitation of specific ligamentous injuries and conditions. Multiple management techniques are presented for lateral ankle sprains and instability, syndesmotic injuries, deltoid and spring ligament injuries, Lisfranc injuries, and plantar plate and sesamoid injuries. Generous clinical photographs and illustrations highlight current techniques and diagnostic algorithms, and selected chapter-associated video segments are included, demonstrating surgical and rehabilitation techniques and equipment. Written and edited by experts in the field who routinely manage these injuries using the most effective techniques, Ligamentous Injuries of the Foot and Ankle is a terrific resource for orthopedic and sports medicine clinicians and rehabilitation providers at all levels.

Ligaments of the Knee: A Machine-Generated Literature Overview

by Giles R. Scuderi Alfred J. Tria

This is the first machine-generated literature overview on the ligaments of the knee. Introduced and curated by experts in knee surgery, it provides a sound summary of the current knowledge base on knee ligamentous anatomy, kinematics and surgical procedures. The auto-summaries have been generated by a recursive clustering algorithm via the Dimensions Auto-summarizer by Digital Science handled by Subject Matter Experts and the editors of this book. The editors of this book selected which SN content should be auto-summarized and decided its order of appearance. Please be aware that these are extractive auto-summaries, which consist of original sentences, but are not representative of its original paper, since we do not show the full length of the publication. Also note that only published SN content is represented here, and that machine-generated books are still at an experimental stage.

Light Harvesting in Photosynthesis (Foundations of Biochemistry and Biophysics)

by Rienk Van Grondelle Roberta Croce Herbert Van Amerongen Ivo Van Stokkum

This landmark collective work introduces the physical, chemical, and biological principles underlying photosynthesis: light absorption, excitation energy transfer, and charge separation. It begins with an introduction to properties of various pigments, and the pigment proteins in plant, algae, and bacterial systems. It addresses the underlying physics of light harvesting and key spectroscopic methods, including data analysis. It discusses assembly of the natural system, its energy transfer properties, and regulatory mechanisms. It also addresses light-harvesting in artificial systems and the impact of photosynthesis on our environment. The chapter authors are amongst the field’s world recognized experts.Chapters are divided into five main parts, the first focused on pigments, their properties and biosynthesis, and the second section looking at photosynthetic proteins, including light harvesting in higher plants, algae, cyanobacteria, and green bacteria. The third part turns to energy transfer and electron transport, discussing modeling approaches, quantum aspects, photoinduced electron transfer, and redox potential modulation, followed by a section on experimental spectroscopy in light harvesting research. The concluding final section includes chapters on artificial photosynthesis, with topics such as use of cyanobacteria and algae for sustainable energy production.

Light Pollution as a New Risk Factor for Human Breast and Prostate Cancers

by Boris A. Portnov Abraham Haim

Humans are diurnal organisms whose biological clock and temporal organization depend on natural light/dark cycles. Changes in the photoperiod are a signal for seasonal acclimatization of physiological and immune systems as well as behavioral patterns. The invention of electrical light bulbs created more opportunities for work and leisure. However, exposure to artificial light at night (LAN) affects our biological clock, and suppresses pineal melatonin (MLT) production. Among its other properties, MLT is an antioncogenic agent, and therefore its suppression increases the risks of developing breast and prostate cancers (BC&PC). To the best of our knowledge, this book is the first to address the linkage between light pollution and BC&PC in humans. It explains several state-of-the-art theories, linking light pollution with BC&PC. It also illustrates research hypotheses about health effects of light pollution using the results of animal models and population-based studies.

Light Therapies: A Complete Guide to the Healing Power of Light

by Jacob Liberman Anadi Martel

A comprehensive guide to the therapeutic benefits of light and color and how they affect our physical and psychological well-being • Shares scientific research on how different wavelengths of light influence our cells, brain function, sleep patterns, and emotional stability • Examines several forms of light therapy, including chromotherapy, heliotherapy, actinotherapy, and thermotherapy • Explains how to use light and color therapy, maximize the benefits of sunlight, and avoid the health risks of new light sources such as compact fluorescents and LEDs Beginning with sun worship in prehistory and sunshine therapies in ancient Egypt, Greece, and India, light has long been associated with the sublime, the divine, and healing. Yet only recently have we begun to understand how different parts of the light spectrum, from infrared to ultraviolet, can affect our physical and psychological well-being. Covering the historic, scientific, and spiritual aspects of light and its role in energy medicine, Anadi Martel explores the vibrational nature of light and the interaction between light, biology, and consciousness. He demonstrates light’s incredible effects on the physical, energetic, and cognitive dimensions of life and examines several forms of light therapy, including chromotherapy (color therapy), heliotherapy (sun therapy), actinotherapy (ultraviolet therapy), and thermotherapy (infrared therapy). He details how to use light therapy daily, get optimal benefits from sunlight, and avoid the health risks of new artificial lighting such as compact fluorescents and LEDs. Combining his own 30 years of research with practical insight from the many phototherapy pioneers he’s encountered, the author examines scientific studies on how specific wavelengths of light influence our cells and DNA, brain function, sleep patterns, and emotional stability; speed the healing of wounds; and are effective in the treatment of disease, including arthritis, stroke, Alzheimer’s, Parkinson’s, and brain and nerve injuries. Exploring the spiritual aspects of light, the author explains why auras and halos have been used to represent sages and saints of all traditions, revealing the intimate link between light and consciousness. Investigating the many laser, monochrome, audiovisual, and infrared machines designed to heal disease and treat emotional disorders, Martel also reveals promising medical applications for light that are currently in development, inviting the reader not only to appreciate the complexities of light but to maximize its therapeutic dimensions.

Light and Specular Microscopy of the Cornea

by Katerina Jirsova

The atlas of the light and specular microscopy of the cornea, particularly of the corneal endothelium presents healthy and pathological corneas as well as corneas prepared for grafting; photographs are taken from donor or patient's corneas. The first section of the atlas shows healthy cornea and its particular layers: the epithelium (superficial and basal cells, subepithelial nerve plexus), stroma and keratocytes, and the endothelium. Blood vessels or palisades of Vogt in limbus are shown as well. The second section that shows corneas processed for grafting is focused on the endothelial layer. The main causes of exclusion of corneas from grafting, such as the presence of dead cells, polymeghatism, pleomorphism, cornea guttata or stromal scars have been shown. The third section shows corneas before and after storage in tissue cultures or hypothermic conditions with the aim to assess suitability of tissue for grafting. Finally, the last section contains photographs of pathological corneal explants.

Light-Based Therapies for Skin of Color

by Elma Baron

Light-based therapies have been a major component of dermatologic practice. Historically, these treatment modalities have been mainly tailored to the treatment of patients with light skin. Principles governing use of light therapies in skin of color are less defined. However, there is a tremendous need to understand the benefits and limitations of these therapeutic options for dark-skinned patients as well. Demographic data in the United States alone indicate that the population and recipients of health care are rapidly changing with regard to skin phototype. Physicians who are involved in the delivery of care for patients with cutaneous problems that can be addressed by light treatments need to be able to fully understand the mechanisms, applications, risks, efficacy, adverse events, and other pertinent issues in considering treatment options for their patients with pigmented skin.

Light-Responsive Nanostructured Systems for Applications in Nanomedicine

by Salvatore Sortino

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Lighting Up the Brain: The Science of Optogenetics

by Marc Zimmer

What if neuroscientists could look inside the human brain and watch individual brain cells send signals to one another? What if they could then control these brain cells to direct thoughts and actions? This may sound like science fiction, but it's actually a scientific revolution called optogenetics. Neuroscientists would like to use this new technology on human brains to uncover secrets about how the brain processes information and drives human behavior. Doctors hope to use optogenetics to restore sight and to treat Alzheimer's disease, Parkinson's disease, depression, and other debilitating or deadly health problems. Discover how the innovative work of leaders in the field is poised to radically transform science, medicine, and human health.

Lightning Flowers: My Journey to Uncover the Cost of Saving a Life

by Katherine E. Standefer

Lightning Flowers weighs the impact modern medical technology has had on the author's life against the social and environmental costs inevitably incurred by the mining that makes such innovation possible — &“utterly spectacular.&” (Rachel Louise Snyder, author of No Visible Bruises) What if a lifesaving medical device causes loss of life along its supply chain? That's the question Katherine E. Standefer finds herself asking one night after being suddenly shocked by her implanted cardiac defibrillator. In this gripping, intimate memoir about health, illness, and the invisible reverberating effects of our medical system, Standefer recounts the astonishing true story of the rare diagnosis that upended her rugged life in the mountains of Wyoming and sent her tumbling into a fraught maze of cardiology units, dramatic surgeries, and slow, painful recoveries. As her life increasingly comes to revolve around the internal defibrillator freshly wired into her heart, she becomes consumed with questions about the supply chain that allows such an ostensibly miraculous device to exist. So she sets out to trace its materials back to their roots. From the sterile labs of a medical device manufacturer in southern California to the tantalum and tin mines seized by armed groups in the Democratic Republic of the Congo to a nickel and cobalt mine carved out of endemic Madagascar jungle, Lightning Flowers takes us on a global reckoning with the social and environmental costs of a technology that promises to be lifesaving but is, in fact, much more complicated. Deeply personal and sharply reported, Lightning Flowers takes a hard look at technological mythos, healthcare, and our cultural relationship to medical technology, raising important questions about our obligations to one another, and the cost of saving one life.

Lightning Injuries: Electrical, Medical, and Legal Aspects

by Christopher Joh Andrews

Lightning Injuries: Electrical, Medical, and Legal Aspects presents a thorough examination of injuries inflicted by lightning strikes. The expertise of acknowledged world authorities from three continents have been brought together to create this truly remarkable volume. Lightning Injuries: Electrical, Medical, and Legal Aspects begins with a short historical review featuring a discussion of the physics of lightning phenomena and the aspects of electrical circuit theory. This review provides the background for following chapters, which address topics such as the epidemiology of lightning injury, the pathogenesis of the features of lightning injury, the clinical aspects of managing patients with lightning injury, and lightning injury mediated by communications systems (including telephones). The book also describes the problem of finding protection against lightning strikes and the issues that arise in legal liability as a result of lightning strikes. The book is written for a diverse audience and includes material that makes it appropriate for all professionals in medical, legal, and technical fields. Never before has such a comprehensive collation of related facets of lightning injury been published within a single volume.

Lights Out: Sleep, Sugar, and Survival

by T. S. Wiley Bent Formby

When it comes to obesity, diabetes, heart disease, cancer, and depression, everything you believe is a lie. With research gleaned from the National Institutes of Health, T. S. Wiley and Bent Formby deliver staggering findings: Americans really are sick from being tired. Diabetes, heart disease, cancer, and depression are rising in our population. We're literally dying for a good night's sleep. Our lifestyle wasn't always this way. It began with the invention of the lightbulb. When we don't get enough sleep in sync with seasonal light exposure, we fundamentally alter a balance of nature that has been programmed into our physiology since Day One. This delicate biological rhythm rules the hormones and neurotransmitters that determine appetite, fertility, and mental and physical health. When we rely on artificial light to extend our day until 11 PM, midnight, and beyond, we fool our bodies into living in a perpetual state of summer. Anticipating the scarce food supply and forced inactivity of winter, our bodies begin storing fat and slowing metabolism to sustain us through the months of hibernation and hunger that never arrive. Our own survival instinct, honed over millennia, is now killing us. Wiley and Formby also reveal: That studies from our own government research prove the role of sleeplessness in diabetes, heart disease, cancer, infertility, mental illness, and premature aging; Why the carbohydrate-rich diets recommended by many health professionals are not only ridiculously ineffective but deadly; Why the lifesaving information that can turn things around is one of the best-kept secrets of our day. Lights Out is one wake-up call none of us can afford to miss.

Lights and Sirens

by Kevin Grange

A true account of going through UCLA's famed Daniel Freeman Paramedic Program--and practicing emergency medicine on the streets of Los Angeles.Nine months of tying tourniquets and pushing new medications, of IVs, chest compressions, and defibrillator shocks--that was Kevin Grange's initiation into emergency medicine when, at age thirty-six, he enrolled in the "Harvard of paramedic schools": UCLA's Daniel Freeman Paramedic Program, long considered one of the best and most intense paramedic training programs in the world.Few jobs can match the stress, trauma, and drama that a paramedic calls a typical day at the office, and few educational settings can match the pressure and competitiveness of paramedic school. Blending months of classroom instruction with ER rotations and a grueling field internship with the Los Angeles Fire Department, UCLA's paramedic program is like a mix of boot camp and med school. It would turn out to be the hardest thing Grange had ever done--but also the most transformational and inspiring.An in-depth look at the trials and tragedies that paramedic students experience daily, Lights and Sirens is ultimately about the best part of humanity--people working together to help save a human life.

Lignocellulosic Ethanol Production from a Biorefinery Perspective: Sustainable Valorization of Waste

by Deepansh Sharma Anita Saini

This book provides an overview of the multi-dimensional approach for the production of ethanol from lignocellulosic biomass. The sustainability of this biofuel, the current and future status of the technology and its role in waste valorization are also addressed.Bioethanol from lignocellulosic material has emerged as an alternative to the traditional first-generation bioethanol. The book also discusses various pretreatment methods for effective separation of the various components of lignocellulosic feedstock as well as their advantages, and limitations. It describes the valorization of lignocellulosic waste through the production of bioethanol and emphasizes the significance of waste utilization in managing the production cost of the fuel. Finally, the utilization of genetically engineered plants and microorganisms to increase the conversion efficiency is reviewed.

Like Sound Through Water

by Edward M. Hallowell Karen J. Foli

Ben was a bright, happy little boy. Yet he was easily distracted, he wouldn't make eye contact, and he couldn't comprehend the simplest things said to him. At age three he still hadn't started talking. Finally, Karen Foli knew she had to act, and she took her son to a speech and hearing clinic. What the clinicians reported chilled her: Ben's speech and language were delayed by one to two years. Testing results and speech therapists suggested problems that included the words "probably retarded and perhaps autistic." But Karen, trusting her mother's intuition, knew that Ben was intelligent and that he was frustrated by his inability to communicate, so she continued to try to help her son. She discovered that he possessed the hallmarks of auditory processing disorder, the aural equivalent of dyslexia. Like Sound Through Water is the story of Karen's struggle to get Ben the help he needed to learn the most basic skill of all: to communicate with the world. She ran the gauntlet of medical disbelievers and pediatric therapists who refused to understand the very new Þndings of auditory processing disorder. Even her husband, a psychiatrist specializing in children's afÞictions, had never heard of APD. Despite this, he kept a steadfast faith in his son. Now, after years of intensive treatment for APD, Ben is an academically successful, hardworking little boy with a bright future to look forward to. Like Sound Through Water is a testament to a mother's love and her devotion to her son's care; it is also an instructive journey for those who are discovering the world of APD and a guidebook to negotiating the land mines of its treatment. Above all, it is a beautifully written tale of hope and optimism.

Likelihood and Bayesian Inference: With Applications in Biology and Medicine (Statistics for Biology and Health)

by Leonhard Held Daniel Sabanés Bové

This richly illustrated textbook covers modern statistical methods with applications in medicine, epidemiology and biology. Firstly, it discusses the importance of statistical models in applied quantitative research and the central role of the likelihood function, describing likelihood-based inference from a frequentist viewpoint, and exploring the properties of the maximum likelihood estimate, the score function, the likelihood ratio and the Wald statistic. In the second part of the book, likelihood is combined with prior information to perform Bayesian inference. Topics include Bayesian updating, conjugate and reference priors, Bayesian point and interval estimates, Bayesian asymptotics and empirical Bayes methods. It includes a separate chapter on modern numerical techniques for Bayesian inference, and also addresses advanced topics, such as model choice and prediction from frequentist and Bayesian perspectives. This revised edition of the book “Applied Statistical Inference” has been expanded to include new material on Markov models for time series analysis. It also features a comprehensive appendix covering the prerequisites in probability theory, matrix algebra, mathematical calculus, and numerical analysis, and each chapter is complemented by exercises. The text is primarily intended for graduate statistics and biostatistics students with an interest in applications.

Likely to Die (An Alexandra Cooper Novel #2)

by Linda Fairstein

The real-life work of sex-crimes prosecutor Linda Fairstein brought "riveting authenticity" (Vanity Fair) to her bestselling debut novel, Final Jeopardy. Now Fairstein's fictional counterpart -- smart and savvy assistant D.A. Alexandra Cooper -- returns in "[a] Grisham-esque page turner" (Time) that puts Alex in the line of fire. New York City's oldest and largest medical center is the scene of a ghastly attack: top neurosurgeon Gemma Dogen is found in her blood-soaked office, where she has been sexually assaulted, stabbed, and designated by the cops as a "likely to die." By the time Alex has plunged into the case, it's a high-profile, media-infested murder investigation with a growing list of suspects from among those who roam the hospital's labyrinthine halls. As Alex's passion to find the killer intensifies, she discovers this hospital is not a place of healing but of deadly peril -- and that she is the next target for lethal violence. A high-style thriller that sweeps from Manhattan to London to Martha's Vineyard, Likely to Die is an exhilarating tale from a justice system insider and provocative novelist.

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